A graph homomorphism is a map between two graphs that preserves adjacency relations. We consider the problem of sampling a random graph homomorphism from a graph $F$ into a large network $mathcal{G}$. We propose two complementary MCMC algorithms for sampling a random graph homomorphisms and establish bounds on their mixing times and concentration of their time averages. Based on our sampling algorithms, we propose a novel framework for network data analysis that circumvents some of the drawbacks in methods based on independent and neigborhood sampling. Various time averages of the MCMC trajectory give us various computable observables, including well-known ones such as homomorphism density and average clustering coefficient and their generalizations. Furthermore, we show that these network observables are stable with respect to a suitably renormalized cut distance between networks. We provide various examples and simulations demonstrating our framework through synthetic networks. We also apply our framework for network clustering and classification problems using the Facebook100 dataset and Word Adjacency Networks of a set of classic novels.

Factor analysis is a flexible technique for assessment of multivariate dependence and codependence. Besides being an exploratory tool used to reduce the dimensionality of multivariate data, it allows estimation of common factors that often have an interesting theoretical interpretation in real problems. However, standard factor analysis is only applicable when the variables are scaled, which is often inappropriate, for example, in data obtained from questionnaires in the field of psychology,where the variables are often categorical. In this framework, we propose a factor model for the analysis of multivariate ordered and non-ordered polychotomous data. The inference procedure is done under the Bayesian approach via Markov chain Monte Carlo methods. Two Monte-Carlo simulation studies are presented to investigate the performance of this approach in terms of estimation bias, precision and assessment of the number of factors. We also illustrate the proposed method to analyze participants' responses to the Motivational State Questionnaire dataset, developed to study emotions in laboratory and field settings.

King's Orphan Schools (New Town, Tas.)

Cheesman, John -- Family.

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There is an urgent need for new, potent anti-tuberculosis (TB) drugs with novel mechanisms of action that can be included in new regimens to shorten the treatment period for TB. After screening a library of carbostyrils, we optimized 3, 4-dihydrocarbostyril derivatives and identified OPC-167832 as having potent anti-tuberculosis activity. The minimum inhibitory concentrations of the compound for Mycobacterium tuberculosis ranged from 0.00024 to 0.002 μg/mL. It had bactericidal activity against both growing and intracellular bacilli, and the frequency of spontaneous resistance for Mycobacterium tuberculosis H37Rv was less than 1.91 x 10^-7. It did not show antagonistic effects with other anti-TB agents in an in vitro checkerboard assay. Whole genome and targeted sequencing of resistant isolates to OPC-167832 identified the decaprenylphosphoryl-β-D-ribose 2'-oxidase (DprE1), an essential enzyme for cell wall biosynthesis, as the target of this compound, and further studies demonstrated inhibition of the DprE1 enzymatic activity by OPC-167832. In a mouse model of chronic TB, OPC-167832 showed potent bactericidal activities starting at a dose of 0.625 mg/kg. Further, it exhibited significant combination effects in 2-drug combinations with delamanid, bedaquiline, or levofloxacin. Finally, 3-4 drug regimens comprised of delamanid and OPC-167832 as the core along with bedaquiline, moxifloxacin, or linezolid showed superior efficacy in reducing bacterial burden and preventing relapse compared to the standard treatment regimen. In summary, these results suggest that OPC-167832 is a novel and potent anti-TB agent and regimens containing OPC-167832 and new or repurposed anti-TB drugs may have the potential to shorten the duration of treatment for TB.

Consumers won nearly 90% of arbitration cases in 2019 The Delaware Department of Insurance announced that its arbitration services program earned residents $839,466 in awards during 2019. Considering overlap from the previous year, 354 settlements occurred, and 144 cases were heard. Residents prevailed in about 90% of all cases. In total, the Department opened 502 […]

आपल्या जगण्यात आपल्याला निश्चिंती हवी असते. आयुष्य चिंतामुक्त, सुखाचं सरावं आणि निर्भयतेनं या जगात आपल्याला वावरता यावं, ही आपली खरी ओढ असते. संत आणि सत्पुरुष आपल्याला तसे जगताना दिसतात.

SMYRNA (May 5, 2020) – The Delaware Division of Public Health (DPH) is announcing five additional fatalities related to coronavirus disease 2019 (COVID-19) and is providing an update on the number of positive cases and recovered individuals. All data reported through the daily updates are based on data received as of 6 p.m. the previous […]

The DoT sent a notice to GAIL soon after the February 14 hearing in the Supreme Court on dues owned by telecom companies such as Bharti Airtel and Vodafone Idea.

Chief among the problems is a lingering crisis at shadow banks that started in 2018, with a shocking default by then high-rated lender IL&FS. The woes mounted last year when major mortgage lender Dewan Housing Finance missed repayments.

A member of the holy trinity, that also included Chuni Goswami and Tulsidas Balaram, Banerjee was the last surviving scorer of the 1962 Asiad gold-winning team.

اس عالمی وبا کے مرکز چین میں اب تک 81ہزار518 افراد کے وائرس سے متاثر ہونے کی تصدیق اور 3305 افراد کی اس وائرس کی زد میں آنے کے بعد موت ہو چکی ہے۔

وزارت صحت کے بیماریوں کے کنٹرول اور روک تھام مرکز (كےسی ڈی سی) نے منگل کو بتایا کہ انفیکشن سے ایک اور شخص کی موت کے ساتھ مرنے والوں کی تعداد 237 ہو گئی جو مجموعی کیسز کا 2.22 فیصد ہے۔

ملک کی 32 ریاستوں اور مرکز کے زیر انتظام علاقوں میں کورونا وائرس کے اب تک کل 40263 کیسز کی تصدیق ہوئی ہے ۔ جن میں 111 غیر ملکی مریض ہیں ۔

ملک بھر میں عالمی وبا کورونا وائرس ’ كووڈ -19‘ کے کیسز میں تیزی سے اضافہ ہو رہا ہے اور گزشتہ 24 گھنٹوں کے دوران 3591 نئے کیسز سامنے آنے کے بعد متاثرین کی تعداد 52,952 ہو چکی ہے

Secunia Security Advisory - A vulnerability has been reported in Inout PPC Engine, which can be exploited by malicious people to conduct cross-site request forgery attacks.

Ubuntu Security Notice 4183-2 - USN-4183-1 fixed vulnerabilities in the Linux kernel. It was discovered that the kernel fix for CVE-2019-0155 was incomplete on 64-bit Intel x86 systems. This update addresses the issue. Various other issues were also addressed.

CentOS Control Web Panel version 0.9.8.836 suffers from a privilege escalation vulnerability.

CentOS Control Web Panel version 0.9.8.836 suffers from an authentication bypass vulnerability.

CentOS Control Web Panel version 0.9.8.838 suffers from a user enumeration vulnerability.

CentOS-WebPanel.com Control Web Panel (CWP) version 0.9.8.836 suffers from a remote command execution vulnerability.

CentOS version 7.6.1810 with Control Web Panel version 0.9.8.837 suffers from a persistent cross site scripting vulnerability.

CentOS version 7.6.1810 with Control Web Panel version 0.9.8.837 suffers from a cross site request forgery vulnerability.

Secunia Security Advisory - A vulnerability has been reported in Juniper Networks Secure Access, which can be exploited by malicious people to bypass certain security restrictions.

Secunia Security Advisory - A vulnerability has been reported in Juniper JunosE, which can be exploited by malicious people to cause a DoS (Denial of Service).

Red Hat Security Advisory 2019-2836-01 - Dovecot is an IMAP server for Linux and other UNIX-like systems, written primarily with security in mind. It also contains a small POP3 server, and supports e-mail in either the maildir or mbox format. The SQL drivers and authentication plug-ins are provided as subpackages. Issues addressed include an out of bounds write vulnerability.

This python script is a fuzzer for the ISO-8385 financial protocol. It is compatible with sulley and bofuzz and is now part of the official bofuzz release.

Red Hat Security Advisory 2019-1833-01 - Red Hat CloudForms Management Engine delivers the insight, control, and automation needed to address the challenges of managing virtual environments. CloudForms Management Engine is built on Ruby on Rails, a model-view-controller framework for web application development. Action Pack implements the controller and the view components. This update fixes various bugs and adds enhancements.

Secunia Security Advisory - A vulnerability has been reported in Apple iPhone iOS, which can be exploited by malicious people to compromise a vulnerable device.

The Moon Jae-in government has decided to pay 100,000 won (US$88) a month per child younger than 5 years beginning in July next year. The basic pension payment of 200,000 won currently given to low-income (lower 70% of income scale) senior citizens older than 65 years will be increased to 250,000 won from April next year.  The additional expenses for these two items will be 13.4 trillion won for children's allowance and 29.5 trillion won for senior citizen pension payments for the next...

(MENAFN - IANS) Jammu, May 9 (IANS) Thirteen more persons tested positive for coronavirus on Saturday in Jammu and Kashmir, taking the patients ta... ......

[Shabelle] The Somali health ministry on Tuesday confirmed 79 new cases of COVID-19, bringing the total number of infections to 835.

PIC18FXXQ83/84 Family Programming Specification

EMC1833

TC3683

TC2683

TC1683

ATA6834C

ATA6833C

MIC833