Donald Trump won the election. The House and Senate are in Republican hands. That means the GOP now owns the debt and its consequences. This responsibility, while too much for past politicians, presents the opportunity of a lifetime: namely, to be the ones who put the government back on fiscal…

An architectural project in Sutton aims to tackle the housing crisis while promoting sustainable development and social inclusion.

[SADC] The Southern African Development Community (SADC) will hold a Joint meeting of the SADC Ministers of Health and Ministers responsible for HIV & AIDS on 7th November 2024 in Harare, the Republic of Zimbabwe.

Fr. John offers a reflection on the recent tragedy in the Gulf of Mexico.

Bishops and priests are most accountable before God for the state of the church. But Fr Thomas reminds us that all of us share responsibility for our church communities and gives practical advice on how to remain faithful and focused.

City of Dreams Manila, part of the Melco Resorts and Entertainment Group, has taken the initiative to promote and observe responsible gaming practices in the Philippines.

A U.S. jury on Tuesday awarded $42 million to three former detainees of Iraq's notorious Abu Ghraib prison, holding a Virginia-based military contractor responsible for contributing to their torture and mistreatment two decades ago.

Is an alarm company responsible for injuries sustained on a routine maintenance call?

Milestone Systems held press meetings during the opening day of ISC West, April 10, for timely discussions on balancing technology innovation and responsibility.

Washington — The U.S. Department of Agriculture’s Food Safety Inspection Service in April approved 15 poultry processing plants’ requests to increase line speeds 25% – despite reported cases of COVID-19 among workers and at least one fatality related to the ongoing pandemic, according to a new policy brief from the National Employment Law Project.

After years of hard work and loyalty, some computers must finally retire. But since they can't take a pension and move to Florida, where do old computers end up?

Responsible extraction in South America’s Lithium Triangle  British Geological Survey

As new evidence about climate change and sea-level rise in South Florida continues to emerge, agencies responsible for the restoration of the Everglades should conduct a mid course assessment that rigorously analyzes scenarios of future change to the region’s ecosystem in its planning, says a new congressionally mandated report by the National Academies of Sciences, Engineering, and Medicine.

A government official said that during the deliberations one of the leaders wondered if AI "replaced or enhanced human skills" and suggested that it should be used in an ethical manner.

The Responsible Woman by James Christensen is a(n) Limited Edition. The Edition is Limited to Limited Edition of 2500 pcs

While hydronic systems have long been recognized for their energy-saving properties in HVAC and plumbing applications, designing an efficient hydronic system and narrowing down the necessary system components can be challenging.

In this excerpt from “That Librarian,” Amanda Jones offers a blueprint to battle book censorship in public libraries.

I've contributed... won't you?

Resemble AI, providers of a platform that uses generative AI to create realistic-sounding voices, in July released Resemble Detect, which can validate the authenticity of audio data to expose speech deepfakes in real time .

Fact-based dramas are bringing more realistic science to the small screen, at a time when we definitely need it.

Vistors to the North Coast 500 are being asked to sign a pledge amin concerns of speeding drivers

Democratic presidential nominee Joe Biden said that President Trump does bear some responsibility for catching COVID-19 last week due to his refusal of not taking social distancing guidelines and not wearing a mask seriously. “Look, anybody who contracts the virus by essentially saying, ‘masks don’t matter; social distancing doesn’t matter’ — I think is responsible […]

The post Biden: Trump Is ‘Responsible’ For Contracting Coronavirus appeared first on Hispolitica.

Mammalian circadian clocks are driven by transcription/translation feedback loops composed of positive transcriptional activators (BMAL1 and CLOCK) and negative repressors (CRYPTOCHROMEs (CRYs) and PERIODs (PERs)). CRYs, in complex with PERs, bind to the BMAL1/CLOCK complex and repress E-box–driven transcription of clock-associated genes. There are two individual CRYs, with CRY1 exhibiting higher affinity to the BMAL1/CLOCK complex than CRY2. It is known that this differential binding is regulated by a dynamic serine-rich loop adjacent to the secondary pocket of both CRYs, but the underlying features controlling loop dynamics are not known. Here we report that allosteric regulation of the serine-rich loop is mediated by Arg-293 of CRY1, identified as a rare CRY1 SNP in the Ensembl and 1000 Genomes databases. The p.Arg293His CRY1 variant caused a shortened circadian period in a Cry1−/−Cry2−/− double knockout mouse embryonic fibroblast cell line. Moreover, the variant displayed reduced repressor activity on BMAL1/CLOCK driven transcription, which is explained by reduced affinity to BMAL1/CLOCK in the absence of PER2 compared with CRY1. Molecular dynamics simulations revealed that the p.Arg293His CRY1 variant altered a communication pathway between Arg-293 and the serine loop by reducing its dynamicity. Collectively, this study provides direct evidence that allosterism in CRY1 is critical for the regulation of circadian rhythm.

The ANC is fully and entirely responsible for the crisis of electricity in South Africa for the past 17 years, and electricity minister Kgosientsho Ramokgopa knows it, says Sikonathi Mantshantsha.

Prosecutors have secured indictments against four defendants charged with multiple carjackings, along with kidnapping, rape, and theft.   On June 5, the Department of Justice secured indictments against Defendants Tonnaire McNair-Matthews, 24, of Wilmington; David Hinson, 21, of Bear; Mahkiya Powell, 20, of Wilmington; and Michael Caldwell, 21, of Wilmington. The charges stem from an April, […]

When HIV virus is at untraceable levels then it is untransmittable, or "undetectable equals untransmittable" (U Equals U). This is the reality of every HIV patient.

Modest personal tax cuts, tighter superannuation concessions, and a pathway to lower corporate tax rates make this a responsible if not spectacular budget.

Chef Matt Orlando of Amass was in Bengaluru recently. He talks about how sustainable living can be a winnable goal

The Responsible Generative AI Toolkit is being expanded with new features to support responsible AI development across all LLMs, including SynthID Text for watermarking.

Hong Kong’s responsible AI framework comes amid increasing international competition and tensions affecting access to AI technology

Let’s take a look at how we can practice responsible tourism and avoid the exploitation of pristine ecosystems and its vulnerable dependents.

Emphasising the increased responsibility following a significant electoral victory, Modi promised to work harder and achieve greater outcomes 

Locally-grown vegetables find their way to My Farm, a farm-to-table set-up near Visakhapatnam, that adopts permaculture to promote sustainability as a way of life

Khan defends his decision to refer the University Amendment Bills to the President and says it was necessitated since the ‘government overstepped its limits’

'Krishna garu was completely broken after the death of his son Ramesh Babu and then, Indira Devi.''His second wife Vijaya Nirmala was also gone.''I think Krishna garu had lost the will to live.'

The future of AI will require new standards to ensure safe and responsible implementation

Environmental News FOR IMMEDIATE RELEASE

Carbon emissions in 2014 remained at the previous year’s levels of 32.3 billion metric tons — a milestone that points to the impact worldwide renewable energy investment is having in the face of a 1.5 percent annual increase in global energy consumption, according to a new report from REN21. The tenth annual Renewables 2015 Global Status Report cites “increased penetration of renewable energy” and improvements in energy efficiency as the chief reasons for the noted emissions stabilization.

Deputy Minister of National Planning and Economic Development, Dr. Khin San Yee, presented her country’s ambitious efforts to improve the investment climate at meetings of the OECD Investment Committee and Advisory Group on Investment and Development from 15-17 October 2013 in Paris.

Participants in this multi-stakeholder meeting reviewed and discussed the implementation of the OECD Due Diligence Guidance and in the 3Ts supply chain to ensure that companies avoid contributing to conflict through their mineral or metal purchasing decisions and practices.

18 November 2013 - Asia-Pacific Trade and Investment Week 2013 opened in Bangkok today with a regional conference on responsible business practices jointly organised by the United Nations Economic and Social Commission of Asia and the Pacific (ESCAP) and the Organisation for Economic Co-operation and Development (OECD).