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Thankfully, Floating Orphanages Were Outlawed At The Turn Of The Century

THAT'S WHERE WE PUT UNWANTED KIDS!!




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Caring for 5,500 orphans

A local partner cares for 5,500 orphans in the Near East, compromising personal health and safety for the children’s sake.




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Wikipedia: George Müller (27 September 1805 - 10 March 1898) -- a Christian evangelist and Director of the Ashley Down orphanage in Bristol, England, cared for 10,024 orphans in his life - He was well-known for providing an education to the children

Youth: Müller was born in Kroppenstaedt (now Kroppenstedt), a village near Halberstadt in the Kingdom of Prussia. In 1810, the Müller family moved to nearby Heimersleben, where Müller's father was appointed a collector of taxes. He had an older brother, Friedrich Johann Wilhelm (1803 - 7 Oct 1838) and, after his widowed father remarried, a half-brother, Franz (b 1822). His early life was not marked by righteousness - on the contrary, he was a thief, a liar and a gambler. By the age of 10, Müller was stealing government money from his father. While his mother was dying, he, at 14 years of age, was playing cards with friends and drinking. Müller's father hoped to provide him with a religious education that would allow him to take a lucrative position as a clergyman in the state church. He studied divinity in the University of Halle, and there met a fellow student (Beta) who invited him to a Christian prayer meeting. There he was welcomed, and he began regularly reading the Bible and discussing Christianity with the others who attended the meetings. After seeing a man praying to God on his knees, he was convinced of his need for salvation. As soon as he got home he went to his bed where he knelt and prayed. He asked God to help him in his life and to bless him wherever he went and to forgive him of his sins. He immediately stopped drinking, stealing and lying, and began hoping to become a missionary. He began preaching regularly in nearby churches and continued meeting with the other churches. -- Early work: In 1828, Müller offered to work with Jews in England through the London Society for Promoting Christianity Amongst the Jews, but upon arriving in 1829, he fell ill, and did not think that he would survive. He was sent to Teignmouth to recuperate and, whilst there, met Henry Craik, who became his life-long friend. When he recovered, however, he dedicated himself to doing the will of God. He soon left the London Society, convinced that God would provide for his needs as he did Christian work. Craik invited him to become a minister with him in Teignmouth and he became the pastor of Ebenezer Chapel in Devon and soon after, married Mary Groves, the sister of Anthony Norris Groves. During his time as the pastor of the church, he refused a regular salary, believing that the practice could lead to church members giving out of duty, not desire. He also eliminated the renting of church pews, arguing that it gave unfair prestige to the rich (based primarily on James 2:1-9). -- Theology: The theology that guided George Müller's work is not widely known, but was shaped by an experience in his mid twenties when he "came to prize the Bible alone as [his] standard of judgement". He records in his Narratives that "That the word of God alone is our standard of judgment in spiritual things; that it can be explained only by the Holy Spirit; and that in our day, as well as in former times, he is the teacher of his people. The office of the Holy Spirit I had not experimentally understood before that time. Indeed, of the office of each of the blessed persons, in what is commonly called the Trinity, I had no experimental apprehension. I had not before seen from the Scriptures that the Father chose us before the foundation of the world; that in him that wonderful plan of our redemption originated, and that he also appointed all the means by which it was to be brought about. Further, that the Son, to save us, had fulfilled the law, to satisfy its demands, and with it also the holiness of God; that he had borne the punishment due to our sins, and had thus satisfied the justice of God. And, further, that the Holy Spirit alone can teach us about our state by nature, show us the need of a Saviour, enable us to believe in Christ, explain to us the Scriptures, help us in preaching, etc. It was my beginning to understand this latter point in particular which had a great effect on me; for the Lord enabled me to put it to the test of experience, by laying aside commentaries, and almost every other book, and simply reading the word of God and studying it. The result of this was, that the first evening that I shut myself into my room, to give myself to prayer and meditation over the Scriptures, I learned more in a few hours than I had done during a period of several months previously. But the particular difference was, that I received real strength for my soul in doing so. I now began to try by the test of the Scriptures the things which I had learned and seen, and found that only those principles which stood the test were really of value."



  • Christian Church History Study
  • 3. 1522 A.D. to 1880 A.D. - Indigenous Bible translations and Church Doctrines era - The Reformation

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Evangelizing Orphans

Dr. Rossi interviews Fr. Nicholas Andruchow, Associate Director of Project Mexico.




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An Urgent Plea from the Hogar Rafael Ayau Orthodox Orphanage

The Hogar Rafael Ayau Orthodox Orphanage in Guatemala City, Guatemala, needs your assistance. Here Bobby Maddex talks with Mother Abbess Ines about the increasingly desperate situation in which the orphanage finds itself. Click here to learn more about the Hogar, and click here to find out how you can help.




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The Russian Orphan Opportunity Fund

Ancient Faith Radio presents an interview with Georgia Williams, one of the founders and an administrator of the Russian Orphan Opportunity Fund (ROOF), about this important organization's needs and ministry opportunities.




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The St. Innocent Orphanage

Bobby Maddex interviews Fr. Nicholas Andruchow, the recently assigned full-time priest to the St. Innocent Orphanage in Tijuana, Mexico, about his work with both the orphanage and Project Mexico.




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Hogar Orphanage - Moving On Up!

Madre Inez (Hogar Rafael Ayau Orphanage) and John Maddex talk about the move of the children from Guatemala City to the beautiful mountains and their new home. Help them finish the project and move in with the construction completely paid off!




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The Miracle in Zone One: Guatemala City's Hogar Raphael Ayau Orthodox Orphanage

In this new audio documentary, exclusive to Ancient Faith Radio, Bobby Maddex takes a trip to the Hogar Raphael Ayau Orthodox Orphanage in Guatemala City, Guatemala. Learn how the orphanage came to be, what takes place there on a daily basis, and why it is truly miraculous beyond measure.




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How Billy met Molly - the orphaned otter who is now part of the family

A man's bond with an orphaned otter changed his life and became a movie hit.







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Christian Alliance for Orphans celebrates 20 years in ministry

Christian Alliance for Orphans celebrated 20 years of ministry at its annual summit where 2,400 supporters from 46 countries came together at Brentwood Baptist Church in Nashville, Tennessee.




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Discovery of 2,586 Orphan Genes in Rosa Chinensis Provides Insights Into Stress Adaptation and Flower Development

A research team has identified 2,586 orphan genes (OGs) in Rosa chinensis, offering new insights into the role of these unique genes in flower development, stress response, and environmental adaptation.




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Discovery of 2,586 Orphan Genes in Rosa Chinensis Provides Insights Into Stress Adaptation and Flower Development

A research team has identified 2,586 orphan genes (OGs) in Rosa chinensis, offering new insights into the role of these unique genes in flower development, stress response, and environmental adaptation.





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Orphaned Baby Elephant Takes a Flight

When Gary Roberts found this orphaned elephant next to its dead mother, he made an attempt to fly it to safety




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New school offers hope to orphans

OM Malawi opens a new school to help educate children in need.




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Visiting orphans

The OM team in Odessa, Ukraine, regularly visits orphanages in the province, bringing love and the good news to children.




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Looking after orphans

OM Ukraine's team in Odessa heads up the annual All-Ukrainian Day of Prayer for Orphans in the Odessa province.




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Odessa orphans: his heart's home

Long-term follower of Jesus, Nikolay, stepped out in faith to help orphans in Ukraine, and partners with OM in this ministry to children.




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Orphanage to lose licence over abuse

An orphanage foundation in Chiang Mai will have its licence revoked by the Social Development and Human Security Ministry (MSDHS) following a complaint alleging that its employees mistreated children between the ages of three and six, according to Minister Varawut Silpa-archa.




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Low-Efficacy Mu Opioid Agonists as Candidate Analgesics: Effects of Novel C-9 Substituted Phenylmorphans on Pain-Depressed Behavior in Mice [Behavioral Pharmacology]

Low-efficacy mu opioid receptor (MOR) agonists may serve as novel candidate analgesics with improved safety relative to high-efficacy opioids. This study used a recently validated assay of pain-depressed behavior in mice to evaluate a novel series of MOR-selective C9-substituted phenylmorphan opioids with graded MOR efficacies. Intraperitoneal injection of dilute lactic acid (IP acid) served as a noxious stimulus to depress locomotor activity by mice in an activity chamber composed of two compartments connected by an obstructed door. Behavioral measures included (1) crosses between compartments (vertical activity over the obstruction) and (2) movement counts quantified as photobeam breaks summed across compartments (horizontal activity). Each drug was tested alone and as a pretreatment to IP acid. A charcoal-meal test and whole-body-plethysmography assessment of breathing in 5% CO2 were also used to assess gastrointestinal (GI) inhibition and respiratory depression, respectively. IP acid produced a concentration-dependent depression in crosses and movement that was optimally alleviated by intermediate- to low-efficacy phenylmorphans with sufficient efficacy to produce analgesia with minimal locomotor disruption. Follow-up studies with two low-efficacy phenylmorphans (JL-2-39 and DC-1-76.1) indicated that both drugs produced naltrexone-reversible antinociception with a rapid onset and a duration of ~1 h. Potency of both drugs increased when behavior was depressed by a lower IP-acid concentration, and neither drug alleviated behavioral depression by a non-pain stimulus (IP lithium chloride). Both drugs produced weaker GI inhibition and respiratory depression than fentanyl and attenuated fentanyl-induced GI inhibition and respiratory depression. Results support further consideration of selective, low-efficacy MOR agonists as candidate analgesics.

SIGNIFICANCE STATEMENT

This study used a novel set of mu opioid receptor (MOR)-selective opioids with graded MOR efficacies to examine the lower boundary of MOR efficacy sufficient to relieve pain-related behavioral depression in mice. Two novel low-efficacy opioids (JL-2-39, DC-1-76.1) produced effective antinociception with improved safety relative to higher- or lower-efficacy opioids, and results support further consideration of these and other low-efficacy opioids as candidate analgesics.




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Orphan Drugs at 30: Will Success Become Too Expensive?

The Orphan Drug Act (ODA) turned 30 this month, demonstrating that good laws really can have an enduring impact. Amidst the celebrations, a reporter asked me a provocative question: can we afford more orphan drugs costing hundreds of thousands of dollars per year? FDA Matters answered “yes.” However, I added a caveat that should worry everyone eager for orphan drugs to succeed. When genomics and personalized medicine become successful, this will multiply the number of rare diseases and the overall cost of orphan drugs, perhaps beyond what the system can bear.




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Understanding orphan drugs: what are they, how are they classified and what are their challenges in the Indian context

While orphan drugs are crucial to treating rare, sometimes debilitating conditions, the high cost of their research and development is a major barrier to their development in India




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Parents hoping to adopt orphans of Wayanad landslide may not have their wish granted

It is estimated that the landslide has robbed five children of their parents; currently they are with their immediate relatives at the relief camp




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Efforts to spread Diwali light among orphans, seniors in Pune




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Caring for 5,500 orphans

A local partner cares for 5,500 orphans in the Near East, compromising personal health and safety for the children’s sake.




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Franklin Templeton CEO tells why India debt funds closed down: This SEBI rule ‘orphaned’ funds

Franklin Templeton shifted part of the blame for the recent winding down of six of its debt mutual funds on to capital markets regulator Securities and Exchange Board of India.




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Orphaned polar bear arrives in New York

The orphaned polar bear cub that was rescued in Alaska earlier this year arrived safely at a new home in Buffalo, N.Y.




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Watch: Plans for a LEED Platinum orphanage

Project Haiti Orphanage and Children's Center will provide a safe and healthy home for Haitian children.



  • Sustainable Business Practices

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An unlikely trip to India turned a tearoom owner into a hero for orphans

Through The Learning Tea in Atlanta, entrepreneur Katrell Christie is helping educate teenage orphan girls in India so they can achieve their dreams.




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Burger King India joins hands with Delhi Police to provide burgers to orphanages

The staff delivering the meals wear protective gear like masks and gloves to ensure safety. Since Covid – 19 outbreak, Burger King says that it has further strengthened its restaurant procedures around food safety, cleanliness and hygiene and increased its sanitization frequency in all restaurants across the country.






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Orphaned kangaroo joeys keep outback volunteers on the hop

Helen Semmens has 12 housemates requiring constant attention and feeding at least four times a day. The upside? They are all joeys.








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Volunteer Diane Kirkland rescues joeys orphaned in car accidents




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GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents

Treating neuropathic pain is challenging and novel non–opioid-based medicines are needed. Using unbiased receptomics, transcriptomic analyses, immunofluorescence, and in situ hybridization, we found that the expression of the orphan GPCR Gpr160 and GPR160 increased in the rodent dorsal horn of the spinal cord following traumatic nerve injury. Genetic and immunopharmacological approaches demonstrated that GPR160 inhibition in the spinal cord prevented and reversed neuropathic pain in male and female rodents without altering normal pain response. GPR160 inhibition in the spinal cord attenuated sensory processing in the thalamus, a key relay in the sensory discriminative pathways of pain. We also identified cocaine- and amphetamine-regulated transcript peptide (CARTp) as a GPR160 ligand. Inhibiting endogenous CARTp signaling in spinal cord attenuated neuropathic pain, whereas exogenous intrathecal CARTp evoked painful hypersensitivity through GPR160-dependent ERK and cAMP response element–binding protein (CREB). Our findings de-orphanize GPR160, identify it as a determinant of neuropathic pain and potential therapeutic target, and provide insights into its signaling pathways. CARTp is involved in many diseases including depression and reward and addiction; de-orphanization of GPR160 is a major step forward understanding the role of CARTp signaling in health and disease.




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A Day in the Life of an Orphan Baby Sloth




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The story of Thomas & Ann Stone family : including Helping Hobart's Orphans, the King's Orphan School for Boys 1831-1836 / Alexander E.H. Stone.

King's Orphan Schools (New Town, Tas.)




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Orphan crops can bring food security to millions of people

Smallholders and people living in rural areas in Africa grow a huge variety of edible plants other than rice, wheat or maize. These crops, including the African yam bean, have long been neglected although they represent an excellent alternative food supplement to most diets. Grown in pockets of tropical Central, West and East Africa, the African yam bean (Sphenostylis stenocarpa) [...]




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New school offers hope to orphans

OM Malawi opens a new school to help educate children in need.




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Visiting orphans

The OM team in Odessa, Ukraine, regularly visits orphanages in the province, bringing love and the good news to children.




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Looking after orphans

OM Ukraine's team in Odessa heads up the annual All-Ukrainian Day of Prayer for Orphans in the Odessa province.




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Odessa orphans: his heart's home

Long-term follower of Jesus, Nikolay, stepped out in faith to help orphans in Ukraine, and partners with OM in this ministry to children.