Image modeling for biomedical organs

(Wed, Nov 13 2024 7:05 PM to TBD) 86 Narragansett/Ridgeland buses are rerouted via Narragansett, Diversey, Austin, Belmont and Narragansett due to street blockage near Narragansett/Wellington.

This week sees me heading to Latvia for a flying visit to Riga. Never been to Latvia and have been looking forward to this trip for a while. Unfortunately I’ve been a little poorly this week so my energy levels are low and so ‘speedy’ may quickly...

Added July 3, 2006:

The number of patients in the U.S. awaiting organ transplantation outpaces the amount of transplants performed in the U.S., and many donated organs are not transplanted each year due to several factors, such as poor organ function, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Almost 110,000 Americans are waiting for organ transplants, but there are significant inequities in who gets access to the waiting list and an eventual transplant. A new report recommends several policy changes to create a more fair, equitable, and patient-focused system for organ allocation.

Introducing KTD BIOLABS Grass-fed Beef Organs: Elevate Your Health Naturally with Nature's Powerhouse!

"The Blueprint: How To Recreate Your Life In 6 Simple Steps"

CD BioSciences recently announced the release of its high-quality, cost-effective C. elegans pharyngeal pumping analysis services for drug screening.

There are different theories of aging, and scientists have found various ways to measure biological age. Mutations that happen in DNA as a result of exposu

There are different theories of aging, and scientists have found various ways to measure biological age. Mutations that happen in DNA as a result of exposu

There are different theories of aging, and scientists have found various ways to measure biological age. Mutations that happen in DNA as a result of exposu

Single-tissue proteomics in Caenorhabditis elegans reveals proteins resident in intestinal lysosome-related organelles  pnas.org

Carmen Bolden Day wants the mystery solved.

Last weekend I had a lively discussion with a friend about Pagans she has met who don’t condone or accept the LGBT community, especially as it is intermingled with Paganism.  She has met some of this ilk (I have not) and described how they do not condone non-straight sexuality when it is expressed in Paganism, and how this type also has a limited view of what should be expressed as Paganism, and other expressions are wrong.

I gave her the impression I was surprised to hear this, but it was not surprise, but shock.  I knew intellectually that this type exists (since all types of everything exist,) but this was the first I had heard of actual encounters with such thinking.

We followers of Earth-based spirituality are persecuted and ridiculed enough with us doing it to ourselves.  Think of how Christine O’Donnell (who has no business holding public office, but that is another story) was openly ridiculed when an old clip of her surfaced where she stated she dabbled in witchcraft.  It tanked whatever chances she had in her Senatorial race, and was it because she was the wrong picture to put on the pagan community?  No, it was because any inference that one is a practicing pagan is social suicide in most parts of the United States.

We pagans need to be accepting of each other, and open to the great cosmos that is all of us.  There is no “right” or “wrong” way to be a pagan.

Those who think otherwise are suffering from cognitive dissonance.

Recent studies have suggested that innate immune responses exhibit characteristics associated with memory linked to modulations in both vertebrates and invertebrates. However, the diverse evolutionary paths taken, particularly within the invertebrate taxa, should lead to similarly diverse innate immunity memory processes. Our understanding of innate immune memory in invertebrates primarily comes from studies of the fruit fly Drosophila melanogaster, the generality of which is unclear. Caenorhabditis elegans typically inhabits soil harboring a variety of fatal microbial pathogens; for this invertebrate, the innate immune system and aversive behavior are the major defensive strategies against microbial infection. However, their characteristics of immunological memory remains infantile. Here we discovered an immunological memory that promoted avoidance and suppressed innate immunity during reinfection with bacteria, which we revealed to be specific to the previously exposed pathogens. During this trade-off switch of avoidance and innate immunity, the chemosensory neurons AWB and ADF modulated production of serotonin and dopamine, which in turn decreased expression of the innate immunity-associated genes and led to enhanced avoidance via the downstream insulin-like pathway. Therefore, our current study profiles the immune memories during C. elegans reinfected by pathogenic bacteria and further reveals that the chemosensory neurons, the neurotransmitter(s), and their associated molecular signaling pathways are responsible for a trade-off switch between the two immunological memories.

One day, doctors might be able to 3D print copies of your organs in order to test a variety of drugs, thanks to a new technique that uses light and sound for rapid printing

Caenorhabditis elegans is an important model organism for human health and disease, with foundational contributions to the understanding of gene expression and tissue patterning in animals. An invaluable tool in modern gene expression research is the presence of a high-resolution ribosome structure, though no such structure exists for C. elegans. Here, we present a high-resolution single-particle cryogenic electron microscopy (cryo-EM) reconstruction and molecular model of a C. elegans ribosome, revealing a significantly streamlined animal ribosome. Many facets of ribosome structure are conserved in C. elegans, including overall ribosomal architecture and the mechanism of cycloheximide, whereas other facets, such as expansion segments and eL28, are rapidly evolving. We identify uL5 and uL23 as two instances of tissue-specific ribosomal protein paralog expression conserved in Caenorhabditis, suggesting that C. elegans ribosomes vary across tissues. The C. elegans ribosome structure will provide a basis for future structural, biochemical, and genetic studies of translation in this important animal system.

One day, doctors might be able to 3D print copies of your organs in order to test a variety of drugs, thanks to a new technique that uses light and sound for rapid printing

Rubbing a common yellow food dye onto a mouse's skin turns it temporarily transparent, so we can monitor its insides without harming the animal

One day, doctors might be able to 3D print copies of your organs in order to test a variety of drugs, thanks to a new technique that uses light and sound for rapid printing

Amidst soaring pollution levels in Delhi, health experts warned on Saturday that poor air quality can adversely impact all our organs. A layer of smog

bHighlights:/bul class="group-list punch-points"li A 28-year-old man who was brain dead had his kidneys, lungs, and liver successfully transplanted

An eight-year-old Nigerian girl who was born with her liver and most of the intestines protrude outside of her abdomen in a sac-like structure was treated successfully by Gurugram doctors.

Cambridge, MA. : National Bureau of Economic Research, 2023

Organ Donation: A tightly regulated practice tainted by acts of fraud, gifts someone a chance at a better health

Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled the field to flourish.

In fact, researchers have learned, the detached male pedipalps transfer more sperm faster after copulation is ended by the female rather than the male.

The post Male spider’s sexual organs work fastest only when a female breaks them off appeared first on Smithsonian Insider.

The number of patients in the U.S. awaiting organ transplantation outpaces the amount of transplants performed in the U.S., and many donated organs are not transplanted each year due to several factors, such as poor organ function, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Image modeling for biomedical organs

Ocean acidification could damage the organs of Atlantic herring, as well as slow their growth and development, recent experiments show. It adds to the list of pressures currently threatening this commercially important species, including over-fishing and marine pollution.

Insects are lower impact and could replace meat in the American diet, but what do the veggies think?

An organic pizza franchise is expanding fast with a menu that boasts vegan cheeses, organic meats, and gluten-free brownies.

The USDA deputy secretary Kathleen Merrigan did a Q&A with The Washington Post about challenges for the organic food market.

To solve organ shortages, some places are making it the norm to have people opt out of organ donation.

Method and apparatus are provided for mechanically processing an organ or organs taken out from slaughtered poultry in a processing device or processing line, which organ or organs form part of an organ package and wherein the organ or organs are separated from the organ package. The organ package is spatially oriented by the processing device without notably breaking tissue connections in the package, and in a preselected order so as to cause the harvesting of organs from the package to occur in a preselected sequence that depends on the location of the organ package in the processing device or processing line.

Method and apparatus are provided for mechanically processing an organ or organs taken out from slaughtered poultry in a processing device or processing line, which organ or organs form part of an organ package and wherein said organ or organs are separated from the organ package. The organ package is spatially oriented by the processing device without notably breaking tissue connections in the package, and in a preselected order so as to cause harvesting of organs from the package to occur in a preselected sequence that depends on the location of the organ package in the processing device or processing line.

Die Lira fällt seit Wochen, die Devisenreserven des Landes sind fast schon aufgezehrt. Das könnte sogar zu einem Staatsbankrott führen. Zwei Länder könnten zwar als Retter einspringen – doch sie würden das Grundproblem der Türkei nicht beheben.

Charlie Demers and Glen Foster refuse to look fuel-ish when they discuss the carbon tax. Then, Evany Rosen and Todd Graham try to stay civil in their debate on city slogans.

It's well established that coronavirus targets the lungs; but a growing body of evidence suggests COVID-19 may also cause blood clots that can damage vital organs, including the kidneys, heart and brain.

The Country Women's Association is set to take on Wicked Campers after one of its members took direct action and painted over of slogans on one of its vans.

(United States First Circuit) - Affirmed the dismissal of an Indian tribe's complaint against federal and Rhode Island agencies concerning a highway bridge reconstruction. The tribe argued, at base, that the state of Rhode Island broke a promise to give the tribe three parcels of land as mitigation for the expected negative impact on historic tribal land of an I-95 bridge replacement project. Agreeing with the district court, the First Circuit held that the tribe's claims were barred by federal sovereign immunity and lack of subject matter jurisdiction.

(United States First Circuit) - Affirmed the dismissal of an Indian tribe's complaint against federal and Rhode Island agencies concerning a highway bridge reconstruction. The tribe argued, at base, that the state of Rhode Island broke a promise to give the tribe three parcels of land as mitigation for the expected negative impact on historic tribal land of an I-95 bridge replacement project. Agreeing with the district court, the First Circuit held that the tribe's claims were barred by federal sovereign immunity and lack of subject matter jurisdiction.

Increased microvascular permeability to plasma proteins and neutrophil emigration are hallmarks of innate immunity and key features of numerous inflammatory disorders. Although neutrophils can promote microvascular leakage, the impact of vascular permeability on neutrophil trafficking is unknown. Here, through the application of confocal intravital microscopy, we report that vascular permeability–enhancing stimuli caused a significant frequency of neutrophil reverse transendothelial cell migration (rTEM). Furthermore, mice with a selective defect in microvascular permeability enhancement (VEC-Y685F-ki) showed reduced incidence of neutrophil rTEM. Mechanistically, elevated vascular leakage promoted movement of interstitial chemokines into the bloodstream, a response that supported abluminal-to-luminal neutrophil TEM. Through development of an in vivo cell labeling method we provide direct evidence for the systemic dissemination of rTEM neutrophils, and showed them to exhibit an activated phenotype and be capable of trafficking to the lungs where their presence was aligned with regions of vascular injury. Collectively, we demonstrate that increased microvascular leakage reverses the localization of directional cues across venular walls, thus causing neutrophils engaged in diapedesis to reenter the systemic circulation. This cascade of events offers a mechanism to explain how local tissue inflammation and vascular permeability can induce downstream pathological effects in remote organs, most notably in the lungs.