cron Micron Technology, Inc. (MU): Citi Analyst Recommends Buy as Semiconductor Selloff Nears Completion, Market Recovery Expected in 2025 - Yahoo Finance By news.google.com Published On :: Thu, 14 Nov 2024 06:48:16 GMT Micron Technology, Inc. (MU): Citi Analyst Recommends Buy as Semiconductor Selloff Nears Completion, Market Recovery Expected in 2025 Yahoo Finance Full Article
cron Micron Amp Effects Pack 1.0 by PatriceEliseEarle By www.maxforlive.com Published On :: Wed, 13 Nov 2024 08:50:48 EST Micron Overdrive v1.0 Max for Live Audio Effect Overdrive is an amplitude-based audio effect ... Full Article
cron EU states must enact key reforms at smaller scale rather than wait for consensus, Draghi, Macron warn By biztoc.com Published On :: Thu, 14 Nov 2024 06:33:37 GMT Donec et orci aliquet nisl suscipit molestie sed sit amet tortor. Duis vel urna ac mi sollicitudin lacinia mollis sit amet lorem. Sed finibus erat nec libero scelerisque fringilla. Morbi at orci sed urna vulputate vulputate. Nulla facilisi. Donec et orci aliquet nisl suscipit molestie sed sit amet… Full Article
cron Législatives : le cadeau de Jospin à Emmanuel Macron... By marc-vasseur.over-blog.com Published On :: Tue, 06 Jun 2017 20:37:05 +0200 On semble s'acheminer vers une vague En Marche de forte magnitude aux prochaines Législatives. Si Les Républicains espèrent limiter la casse, c'est à dire avec un perte d'une centaine de députés. L'enjeu de LR, c'est l'après avec en ligne de mire, un... Full Article
cron Emmanuel Macron et les Réseaux Sociaux By marc-vasseur.over-blog.com Published On :: Tue, 19 Mar 2019 12:45:00 +0100 C’est entendu pour Emmanuel Macron, les violences auraient pour cause les Réseaux Sociaux. Je cite « il y a un changement anthropologique de nos sociétés qui vient des réseaux sociaux ». J’avoue que ce type de raisonnement aussi simplistes me laisse pantois.... Full Article
cron Notre-Dame de Paris : discours d'Emmanuel Macron, première messe, ouverture au public… Découvrez le calendrier de la réouverture de la cathédrale - franceinfo By news.google.com Published On :: Wed, 13 Nov 2024 12:34:06 GMT Notre-Dame de Paris : discours d'Emmanuel Macron, première messe, ouverture au public… Découvrez le calendrier de la réouverture de la cathédrale franceinfoRéouverture de Notre-Dame : Emmanuel Macron s’exprimera «sur le parvis» de la cathédrale Le FigaroRéouverture de Notre-Dame de Paris : le calendrier dévoilé, une bonne nouvelle pour les visiteurs actu.frNotre-Dame : la cathédrale ouvrira au public du 8 au 14 décembre "jusqu'à 22 heures" RTLCérémonies, huit jours de fête, visites: ce qu'il faut savoir sur la réouverture de Notre-Dame de Paris BFM Paris Ile-de-France Full Article
cron Billions globally consume insufficient levels of vital micronutrients By tribune.com.pk Published On :: Sat, 31 Aug 24 20:13:46 +0500 The study is the first to provide global picture of inadequate consumption of 15 micronutrients useful for humans Full Article Technology
cron Micron falls after Edgewater sees softening outlook in 2025 By finance.yahoo.com Published On :: 2024-11-13T12:11:16Z Full Article
cron Terms and acronyms of protective apparel By www.safetyandhealthmagazine.com Published On :: Tue, 24 May 2022 00:00:00 -0400 What are the common terms of protective apparel, and what do they mean? Full Article
cron SternVitamin: Micronutrient Solutions By www.preparedfoods.com Published On :: Tue, 28 Sep 2021 14:00:00 -0400 Health is one of the 12 megatrends recently defined by the Future Institute in Frankfurt. It informs all facets of daily life and dominates entire lifestyles. Full Article
cron Fearing Le Pen, the left saves Macron and recovers "pink neoliberalism" By english.pravda.ru Published On :: Tue, 09 Jul 2024 12:20:00 +0300 The big loser in the French elections was not the far right. It's true that if it hadn't been for the spurious agreements between the New Popular Front and the Macronists, the National Regroupment would have grown even more. But the result of the second round is not exactly a victory for the left. After Marine Le Pen's RN led the first round of the elections, the leaders of the NFP fell into the trap of the French press and Emmanuel Macron, abandoning numerous candidates of their own to increase the chances of the neoliberal right linked to the Renaissance party beating the far right. The French big bourgeoisie called for a "republican front" to create a "cordon sanitaire" made up of the left and the neoliberal right in order to prevent a landslide victory for the RN, which led to agreements in around 220 constituencies for the candidate with supposedly the least chance of winning the RN to abandon the race in favour of the candidate with the greatest chance. Except that most of the abandonments were by the NFP so that Macron's allies could beat Le Pen's allies, even though the NFP came second in the first round, far ahead of Macron's coalition. Full Article Opinion
cron More contagious COVID-19 BA.2 omicron to take over the U.S. By english.pravda.ru Published On :: Tue, 05 Apr 2022 12:20:00 +0300 Centrers for Disease Control and Prevention suggest that the more contagious subvariant BA.2 of omicron strain now makes up 72% of COVID-19 infections in the U.S. According to the data, the BA.2 is able to displace all other COVID-19 strains and its subvariants. Ali Mokdad, an epidemiologist at the Institute for Health Metrics and Evaluation in Washington state, estimates that the displacement might happen in the next two weeks. According to different sources, the BA.2 is from 30% to 80% more contagious than the BA.1. A top WHO official, Maria Van Kerkhove, describes BA.2 as the most transmissible version of the virus so far. Full Article Health
cron Redetermination of germacrone type II based on single-crystal X-ray data By journals.iucr.org Published On :: 2024-04-26 The extraction and purification procedures, crystallization and crystal structure refinement (single-crystal X-ray data) of germacrone type II, C15H22O, are presented. The structural results are compared with a previous powder X-ray synchrotron study [Kaduk et al. (2022). Powder Diffr. 37, 98–104], revealing significant improvements in terms of accuracy and precision. Hirshfeld atom refinement (HAR), as well as Hirshfeld surface analysis, give insight into the intermolecular interactions of germacrone type II. Full Article text
cron Elastic and inelastic strain in submicron-thick ZnO epilayers grown on r-sapphire substrates by metal–organic vapour phase deposition By journals.iucr.org Published On :: 2024-02-13 A significant part of the present and future of optoelectronic devices lies on thin multilayer heterostructures. Their optical properties depend strongly on strain, being essential to the knowledge of the stress level to optimize the growth process. Here the structural and microstructural characteristics of sub-micron a-ZnO epilayers (12 to 770 nm) grown on r-sapphire by metal–organic chemical vapour deposition are studied. Morphological and structural studies have been made using scanning electron microscopy and high-resolution X-ray diffraction. Plastic unit-cell distortion and corresponding strain have been determined as a function of film thickness. A critical thickness has been observed as separating the non-elastic/elastic states with an experimental value of 150–200 nm. This behaviour has been confirmed from ultraviolet photoelectron spectroscopy, X-ray photoelectron spectroscopy and high-resolution transmission electron microscopy measurements. An equation that gives the balance of strains is proposed as an interesting method to experimentally determine this critical thickness. It is concluded that in the thinnest films an elongation of the Zn—O bond takes place and that the plastic strained ZnO films relax through nucleation of misfit dislocations, which is a consequence of three-dimensional surface morphology. Full Article text
cron VMXm – A sub-micron focus macromolecular crystallography beamline at Diamond Light Source By journals.iucr.org Published On :: 2024-10-30 VMXm joins the suite of operational macromolecular crystallography beamlines at Diamond Light Source. It has been designed to optimize rotation data collections from protein crystals less than 10 µm and down to below 1 µm in size. The beamline has a fully focused beam of 0.3 × 2.3 µm (vertical × horizontal) with a tuneable energy range (6–28 keV) and high flux (1.6 × 1012 photons s−1 at 12.5 keV). The crystals are housed within a vacuum chamber to minimize background scatter from air. Crystals are plunge-cooled on cryo-electron microscopy grids, allowing much of the liquid surrounding the crystals to be removed. These factors improve the signal-to-noise during data collection and the lifetime of the microcrystals can be prolonged by exploiting photoelectron escape. A novel in vacuo sample environment has been designed which also houses a scanning electron microscope to aid with sample visualization. This combination of features at VMXm allows measurements at the physical limits of X-ray crystallography on biomacromolecules to be explored and exploited. Full Article text
cron BeSang Inc. Statement on Patent Infringement Lawsuits Against Micron and Intel By www.24-7pressrelease.com Published On :: Thu, 26 Jan 2023 08:00:00 GMT IP Litigations Regarding 3D NAND Flash Memory Full Article
cron WP Cron has broken since 2.9 update By wpcult.com Published On :: Wed, 06 Nov 2024 18:08:22 +0000 Did you make the update to WordPress 2.9? Well you may want to check out this post regarding an issues with WP Cron, which controls you auto (scheduled) posts. I know one of my sites has an issue, so I installed the three files and it fixed the issue. The post WP Cron has broken since 2.9 update appeared first on WPCult. Full Article Cult 2.9 bug Bug Fix WordPress
cron How to Use a Micron Gauge By www.achrnews.com Published On :: Thu, 27 Jan 2022 07:00:00 -0500 Many technicians believe that a vacuum pump actually pumps ‘liquid’ moisture out of a system. This is not true. Full Article
cron Meler's Micron+ Adhesive Systems Improve Packaging Line Efficiency By www.packagingstrategies.com Published On :: Thu, 09 Apr 2020 00:00:00 -0400 Key benefits include an innovative tank construction that ensures uniform melt temperatures with no hotspots, char or waste; a horizontal piston pump design that provides consistent, direct adhesive feed; and a high efficiency design that uses 60% less energy and 50% less compressed air than comparable systems. Full Article
cron Internet Acronyms, Abbreviations and Emoticons - A Note By www.assessmentpsychology.com Published On :: Tue, 30 Sep 2008 04:00:00 UTC A note by Dr. Benet about Internet Acronyms, Abbreviations and Emoticons by AssessmentPsychology.com. Full Article
cron Internet Acronyms, Abbreviations and Emoticons By www.assessmentpsychology.com Published On :: Tue, 30 Sep 2008 04:00:00 UTC Find Internet acronyms, abbreviations and emoticons by AssessmentPsychology.com. Full Article
cron Your SSD Is Not As Capacious As Micron's Beastly New 60TB PCIe 5.0 Storage Drive By hothardware.com Published On :: Tue, 12 Nov 2024 17:00:00 -0500 When you think of bulk storage, you probably still think about hard drives, and that's fair enough; spinning rust still offers superior value in terms of price per gigabyte. When storage density is more important than value, though, solid-state drives win again. That's because there are SSDs like Micron's new ION 6550, which can store up to Full Article
cron [ J.1 (01/19) ] - Terms, definitions and acronyms for television and sound transmission and integrated broadband cable networks By www.itu.int Published On :: Mon, 25 Nov 2019 14:10:00 GMT Terms, definitions and acronyms for television and sound transmission and integrated broadband cable networks Full Article
cron Micron launches 60TB PCIe gen5 SSD with 12GB/s read speeds By www.micron.com Published On :: Wed, 13 Nov 2024 02:53:13 +0000 Comments Full Article
cron Market Whales and Their Recent Bets on Micron Technology Options - Benzinga By news.google.com Published On :: Tue, 12 Nov 2024 15:15:54 GMT Market Whales and Their Recent Bets on Micron Technology Options Benzinga Full Article
cron Marc Rutte, con Macron: "Los vínculos de Rusia con Corea del Norte, Irán y China son una amenaza para Europa" By www.elmundo.es Published On :: Tue, 12 Nov 2024 19:53:16 +0100 El presidente francés recibe al secretario general de la OTAN en el Elíseo y ambos insisten en la necesidad de seguir apoyando a Ucrania. Leer Full Article Emmanuel Macron Francia OTAN Artículos Raquel Villaécija Especial Guerra de Ucrania
cron Histórico triunfo de Evenepoel en la crono del Mundial: Doblete consecutivo tras ganar dos oros en los Juegos Olímpicos By www.elmundo.es Published On :: Sun, 22 Sep 2024 19:36:09 +0200 El belga, que derrotó al italiano Filippo Ganna en Zúrich, firma una temporada espléndida y aún aspira a otra medalla en la prueba en ruta Leer Full Article deportes ciclismo Remco Evenepoel Tadej Pogacar Mundial de Ciclismo Artículos Pablo de la Calle
cron Medalla de oro en crono sub 23 para Iván Romeo, el nuevo gigante del ciclismo español By www.elmundo.es Published On :: Mon, 23 Sep 2024 18:28:38 +0200 El vallisoletano, integrante del equipo Movistar, firma una ejercicio excepcional en el Mundial de Zúrich Leer Full Article deportes ciclismo Mundial de Ciclismo Artículos Pablo de la Calle
cron The role of micronutrients during COVID-19 By federalnewsnetwork.com Published On :: Mon, 21 Dec 2020 20:41:17 +0000 Dana Laake and her special guest Dr. Bernarda Zenker will discuss the role of micronutrients during COVID-19. The post The role of micronutrients during COVID-19 first appeared on Federal News Network. Full Article All News Analysis Essentials of Healthy Living Federal Insights Radio Interviews Bernarda Zenker Dana Laake Village Green Apothecary
cron Macron: France will 'drive innovation ecosystem of Tech,' president tells Euronews Next By www.euronews.com Published On :: Wed, 16 Jun 2021 19:19:37 +0200 Macron: France will 'drive innovation ecosystem of Tech,' president tells Euronews Next Full Article
cron Los seres vivos sincronizados con los ciclos lunares. By www.spreaker.com Published On :: Fri, 20 Aug 2021 21:32:57 +0000 Los seres vivos sincronizados con los ciclos lunares. Full Article
cron ¿Cómo es estilo de vida puede ayudar a mejorar o cronificar la migraña? By www.spreaker.com Published On :: Sat, 23 Apr 2022 15:42:25 +0000 ¿Cómo es estilo de vida puede ayudar a mejorar o cronificar la migraña? Full Article
cron Cronobiología: reloj biológico que regula nuestro organismo By www.spreaker.com Published On :: Fri, 18 Aug 2023 17:13:00 +0000 Full Article
cron New CRON#TRAP Malware Infects Windows by Hiding in Linux VM to Evade Antivirus By thehackernews.com Published On :: Fri, 08 Nov 2024 12:45:00 +0530 Cybersecurity researchers have flagged a new malware campaign that infects Windows systems with a Linux virtual instance containing a backdoor capable of establishing remote access to the compromised hosts. The "intriguing" campaign, codenamed CRON#TRAP, starts with a malicious Windows shortcut (LNK) file likely distributed in the form of a ZIP archive via a phishing email. "What makes the CRON# Full Article
cron Macronutrients Unveiled: A Comprehensive Look at Their Roles in a Balanced Diet By www.star2.org Published On :: Tue, 23 Apr 2024 13:58:01 +0000 Welcome to an enlightening exploration into the world of macronutrients. These fundamental components of our diet — proteins, carbohydrates, and fats — play integral roles in our body’s physiological functions. While they’re clearly important to our health and well-being, they often remain shrouded in mystery for most of us. By learning more about macronutrients, you’ll understand how ... Read more The post Macronutrients Unveiled: A Comprehensive Look at Their Roles in a Balanced Diet appeared first on Star Two. Full Article Health Balanced Diet Carbohydrates Daily Meals Fats macronutrients Metabolism Proteins
cron Une Nouvelle Révolution? Macron and the Gilets Jaunes By f1.media.brightcove.com Published On :: Wed, 23 Jan 2019 00:00:00 +0000 Full Article
cron Ascertaining the biochemical function of an essential pectin methylesterase in the gut microbe Bacteroides thetaiotaomicron [Metabolism] By www.jbc.org Published On :: 2020-12-25T00:06:31-08:00 Pectins are a major dietary nutrient source for the human gut microbiota. The prominent gut microbe Bacteroides thetaiotaomicron was recently shown to encode the founding member (BT1017) of a new family of pectin methylesterases essential for the metabolism of the complex pectin rhamnogalacturonan-II (RG-II). However, biochemical and structural knowledge of this family is lacking. Here, we showed that BT1017 is critical for the metabolism of an RG-II–derived oligosaccharide ΔBT1017oligoB generated by a BT1017 deletion mutant (ΔBT1017) during growth on carbohydrate extract from apple juice. Structural analyses of ΔBT1017oligoB using a combination of enzymatic, mass spectrometric, and NMR approaches revealed that it is a bimethylated nonaoligosaccharide (GlcA-β1,4-(2-O-Me-Xyl-α1,3)-Fuc-α1,4-(GalA-β1,3)-Rha-α1,3-Api-β1,2-(Araf-α1,3)-(GalA-α1,4)-GalA) containing components of the RG-II backbone and its side chains. We showed that the catalytic module of BT1017 adopts an α/β-hydrolase fold, consisting of a central twisted 10-stranded β-sheet sandwiched by several α-helices. This constitutes a new fold for pectin methylesterases, which are predominantly right-handed β-helical proteins. Bioinformatic analyses revealed that the family is dominated by sequences from prominent genera of the human gut microbiota, including Bacteroides and Prevotella. Our re-sults not only highlight the critical role played by this family of enzymes in pectin metabolism but also provide new insights into the molecular basis of the adaptation of B. thetaiotaomicron to the human gut. Full Article
cron Chylomicronemia from GPIHBP1 autoantibodies [Reviews] By www.jlr.org Published On :: 2020-11-01T00:05:43-07:00 Some cases of chylomicronemia are caused by autoantibodies against glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1), an endothelial cell protein that shuttles LPL to the capillary lumen. GPIHBP1 autoantibodies prevent binding and transport of LPL by GPIHBP1, thereby disrupting the lipolytic processing of triglyceride-rich lipoproteins. Here, we review the "GPIHBP1 autoantibody syndrome" and summarize clinical and laboratory findings in 22 patients. All patients had GPIHBP1 autoantibodies and chylomicronemia, but we did not find a correlation between triglyceride levels and autoantibody levels. Many of the patients had a history of pancreatitis, and most had clinical and/or serological evidence of autoimmune disease. IgA autoantibodies were present in all patients, and IgG4 autoantibodies were present in 19 of 22 patients. Patients with GPIHBP1 autoantibodies had low plasma LPL levels, consistent with impaired delivery of LPL into capillaries. Plasma levels of GPIHBP1, measured with a monoclonal antibody–based ELISA, were very low in 17 patients, reflecting the inability of the ELISA to detect GPIHBP1 in the presence of autoantibodies (immunoassay interference). However, GPIHBP1 levels were very high in five patients, indicating little capacity of their autoantibodies to interfere with the ELISA. Recently, several GPIHBP1 autoantibody syndrome patients were treated successfully with rituximab, resulting in the disappearance of GPIHBP1 autoantibodies and normalization of both plasma triglyceride and LPL levels. The GPIHBP1 autoantibody syndrome should be considered in any patient with newly acquired and unexplained chylomicronemia. Full Article
cron Starmer, Macron reaffirm 'ironclad' support for Ukraine amid uncertainty around Trump By www.upi.com Published On :: Mon, 11 Nov 2024 10:11:44 -0500 French President Emmanuel Macron was joined in Paris on Monday by British Prime Minister Keir Starmer for Armistice Day commemorations after a meeting at which both leaders reaffirmed "unwavering" support for Ukraine. Full Article
cron Micron’s 6550 ION 60TB SSD Advances High-Capacity Storage for HPC and AI Workloads By www.hpcwire.com Published On :: Tue, 12 Nov 2024 21:47:21 +0000 BOISE, Idaho, Nov. 12, 2024 — Micron Technology, Inc. today announced it has begun qualification of the 6550 ION NVMe SSD with customers. The Micron 6550 ION is the world’s […] The post Micron’s 6550 ION 60TB SSD Advances High-Capacity Storage for HPC and AI Workloads appeared first on HPCwire. Full Article
cron Syncroness uses COSMOSMotion analysis technology to design high-quality, complex mechanisms in less time at lower cost By www.solidworks.com Published On :: Mon, 30 Oct 2006 00:00:00 -0500 Cutting days and weeks from design cycle gives Syncroness more time to focus on designing lightweight, high performance products Full Article
cron News24 Business | PODCAST | SA Money Report: The Putin crony, the Naspers money and tensions in Mother Russia By www.news24.com Published On :: Friday Mar 04 2022 13:09:51 This week, SA Money Report journeys in the heart of war, and comes back with a tale about Naspers' exposure in Russia, and its ties to VKontakte, whose 38-year-old CEO Vladimir Kiriyenko was sanctioned by the US. Full Article
cron State’s First Omicron Cases Involve 4 Residents of New Castle County By news.delaware.gov Published On :: Sat, 18 Dec 2021 00:46:30 +0000 DOVER, DE (Dec. 17, 2021) – The Delaware Division of Public Health (DPH) today announced that it has confirmed the first four cases of the Omicron variant (B.1.1.529) among Delaware residents. The variant was detected today through routine sequencing of test specimens by the Delaware Public Health Laboratory. The four cases involve two adults in […] Full Article Delaware Health and Social Services Division of Public Health News #Omicron COVID-19 Delaware variant
cron Federated States of Micronesia President Panuelo Visits East-West Center By www.eastwestcenter.org Published On :: Wed, 21 Jul 2021 19:21:30 +0000 Federated States of Micronesia President Panuelo Visits East-West Center Federated States of Micronesia President Panuelo Visits East-West Center brophyc Wed, 07/21/2021 - 09:21 Jul 21, 2021 Jul 21, 2021 Federated States of Micronesia Federated States of Micronesia News Release Home EWC Feeds Explore search All Programs All Regions All Topics Release Date Filters Reset filters News Release Home EWC Feeds Explore search All Programs All Regions All Topics Release Date Filters Reset filters Full Article
cron New Report: Federated States of Micronesia Faces Stronger Storms, Health Threats, and Challenges for Atolls and Fisheries from Climate Change By www.eastwestcenter.org Published On :: Tue, 18 Jul 2023 00:08:26 +0000 New Report: Federated States of Micronesia Faces Stronger Storms, Health Threats, and Challenges for Atolls and Fisheries from Climate Change New Report: Federated States of Micronesia Faces Stronger Storms, Health Threats, and Challenges for Atolls and Fisheries from Climate Change ferrard Mon, 07/17/2023 - 14:08 Jul 18, 2023 Jul 18, 2023 Environment & Climate Environment & Climate Federated States of Micronesia Federated States of Micronesia News Release Home EWC Feeds Explore search All Programs All Regions All Topics Release Date Filters Reset filters News Release Home EWC Feeds Explore search All Programs All Regions All Topics Release Date Filters Reset filters Full Article
cron East-West Center Hosts Inaugural Micronesian Conference of Leaders By www.eastwestcenter.org Published On :: Fri, 18 Oct 2019 01:42:40 +0000 East-West Center Hosts Inaugural Micronesian Conference of Leaders East-West Center Hosts Inaugural Micronesian Conference of Leaders hasegaws Thu, 10/17/2019 - 15:42 Oct 17, 2019 Oct 17, 2019 Governance Governance Politics & International Relations Politics & International Relations Pacific Pacific Marshall Islands Marshall Islands Federated States of Micronesia Federated States of Micronesia Palau Palau News Release Home EWC Feeds Explore search All Programs All Regions All Topics Release Date Filters Reset filters News Release Home EWC Feeds Explore search All Programs All Regions All Topics Release Date Filters Reset filters Full Article
cron Micronesian leaders unified on having an equal voice to other Pacific countries By www.eastwestcenter.org Published On :: Tue, 27 Oct 2020 00:25:00 +0000 Micronesian leaders unified on having an equal voice to other Pacific countries Micronesian leaders unified on having an equal voice to other Pacific countries hasegaws Mon, 10/26/2020 - 14:25 Oct 26, 2020 Oct 26, 2020 Politics & International Relations Politics & International Relations Federated States of Micronesia Federated States of Micronesia East-West Wire Tagline News, Commentary, and Analysis Home EWC Feeds East-West Wire The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here. For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists. Explore search All Programs All Regions All Topics Release Date Filters Reset filters East-West Wire Tagline News, Commentary, and Analysis Home EWC Feeds East-West Wire The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here. For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists. Explore search All Programs All Regions All Topics Release Date Filters Reset filters Full Article
cron Macron and Starmer lay wreath at Paris' Tomb of the Unknown Soldier on Armistice Day By www.euronews.com Published On :: Mon, 11 Nov 2024 16:32:49 +0100 Macron and Starmer lay wreath at Paris' Tomb of the Unknown Soldier on Armistice Day Full Article
cron Pfizer Asks FDA to Approve Omicron-Specific Booster Shot By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Pfizer Asks FDA to Approve Omicron-Specific Booster ShotCategory: Health NewsCreated: 8/22/2022 12:00:00 AMLast Editorial Review: 8/23/2022 12:00:00 AM Full Article
cron Microneedle Glucose Sensors Keep Monitoring Skin-Deep By spectrum.ieee.org Published On :: Tue, 11 Jun 2024 11:00:05 +0000 For people with diabetes, glucose monitors are a valuable tool to monitor their blood sugar. The current generation of these biosensors detect glucose levels with thin, metallic filaments inserted in subcutaneous tissue, the deepest layer of the skin where most body fat is stored.Medical technology company Biolinq is developing a new type of glucose sensor that doesn’t go deeper than the dermis, the middle layer of skin that sits above the subcutaneous tissue. The company’s “intradermal” biosensors take advantage of metabolic activity in shallower layers of skin, using an array of electrochemical microsensors to measure glucose—and other chemicals in the body—just beneath the skin’s surface. Biolinq just concluded a pivotal clinical trial earlier this month, according to CEO Rich Yang, and the company plans to submit the device to the U.S. Food and Drug Administration for approval at the end of the year. In April, Biolinq received US $58 million in funding to support the completion of its clinical trials and subsequent submission to the FDA.Biolinq’s glucose sensor is “the world’s first intradermal sensor that is completely autonomous,” Yang says. While other glucose monitors require a smartphone or other reader to collect and display the data, Biolinq’s includes an LED display to show when the user’s glucose is within a healthy range (indicated by a blue light) or above that range (yellow light). “We’re providing real-time feedback for people who otherwise could not see or feel their symptoms,” Yang says. (In addition to this real-time feedback, the user can also load long-term data onto a smartphone by placing it next to the sensor, like Abbott’s FreeStyle Libre, another glucose monitor.) More than 2,000 microsensor components are etched onto each 200-millimeter silicon wafer used to manufacture the biosensors.BiolinqBiolinq’s hope is that its approach could lead to sustainable changes in behavior on the part of the individual using the sensor. The device is intentionally placed on the upper forearm to be in plain sight, so users can receive immediate feedback without manually checking a reader. “If you drink a glass of orange juice or soda, you’ll see this go from blue to yellow,” Yang explains. That could help users better understand how their actions—such as drinking a sugary beverage—change their blood sugar and take steps to reduce that effect.Biolinq’s device consists of an array of microneedles etched onto a silicon wafer using semiconductor manufacturing. (Other glucose sensors’ filaments are inserted with an introducer needle.) Each chip has a small 2-millimeter by 2-millimeter footprint and contains seven independent microneedles, which are coated with membranes through a process similar to electroplating in jewelry making. One challenge the industry has faced is ensuring that microsensors do not break at this small scale. The key engineering insight Biolinq introduced, Yang says, was using semiconductor manufacturing to build the biosensors. Importantly, he says, silicon “is harder than titanium and steel at this scale.”Miniaturization allows for sensing closer to the surface of the skin, where there is a high level of metabolic activity. That makes the shallow depth ideal for monitoring glucose, as well as other important biomarkers, Yang says. Due to this versatility, combined with the use of a sensor array, the device in development can also monitor lactate, an important indicator of muscle fatigue. With the addition of a third data point, ketones (which are produced when the body burns fat), Biolinq aims to “essentially have a metabolic panel on one chip,” Yang says. Using an array of sensors also creates redundancy, improving the reliability of the device if one sensor fails or becomes less accurate. Glucose monitors tend to drift over the course of wear, but with multiple sensors, Yang says that drift can be better managed. One downside to the autonomous display is the drain on battery life, Yang says. The battery life limits the biosensor’s wear time to 5 days in the first-generation device. Biolinq aims to extend that to 10 days of continuous wear in its second generation, which is currently in development, by using a custom chip optimized for low-power consumption rather than off-the-shelf components.The company has collected nearly 1 million hours of human performance data, along with comparators including commercial glucose monitors and venous blood samples, Yang says. Biolinq aims to gain FDA approval first for use in people with type 2 diabetes not using insulin and later expand to other medical indications.This article appears in the August 2024 print issue as “Glucose Monitor Takes Page From Chipmaking.” Full Article Glucose sensors Diabetes Semiconductors