1. Vikrant Massey says older brother Moeen ‘compromised’ in life, father ‘lived a life of affluence’ before losing it all: ‘I didn’t want to do that’  The Indian Express
2. Did You Know Vikrant Massey’s parents were neighbors of the Kapoor family? Actor reveals they stayed in godowns  PINKVILLA
3. This actor's mother is Sikh, father is Christian, brother is Muslim, wife Hindu, she used to lend...  Bollywood Life
4. 7 must-watch investigative thrillers on OTT ahead of Vikrant Massey’s The Sabarmati Report release  OTTplay
5. Vikrant Massey Compares Early Years Struggle To A Classic Hindi Film: 'Family Fued, Living In Godowns, Mother Doing...'  ABP Live

Bioethicist Wesley J. Smith joins Fr. Barnabas on this last show of 2015 to discuss the alarming societal attitudes toward the value of a human life.

Intriguing new research suggests that by blocking inflammation (or its effects on the brain), it may be possible to help depressed individuals who fail to respond to antidepressants...

Making extensive use of the Scriptures, join Michael Haldas as he teaches an in-depth Bible lesson on the truth about truth; the truth about the real gravity and depravity of lies and lying; and what Christ means when He talks about the “father of lies” and “the ruler of this world” who was “a murderer from the beginning.”

In the face of criticism, Wrexham captain James McClean says he will not compromise his convictions after explaining why he opts not to wear a poppy for Remembrance Day.

...

There’s no doubt about it, working on a railroad can be tough on work boots. See how Dallas, Garland & Northeastern Railroad realized the importance of quality and durability when it came to protecting its crew with the right footwear for the job.

Accurate reporting of outcomes is crucial for interpreting the results of randomized controlled trials (RCTs). However, selectively reporting outcomes in publications to achieve researchers’ anticipated result… Read the full article ›

The post Impact of selective reporting bias on stroke trials: potential compromise in evidence synthesis – A cross-sectional study was curated by information for practice.

By Gareth Hunt, freelance writer.

One of the world's most important currencies is information. That information could be about anybody and anything and may be used in a million different ways. With this much personal information people put on the internet, it becomes effortless for cyber criminals to get that information and perpetrate identity thefts.

In a world of ever-advancing technology and development, many company heads often get lost in the bustle and get swept up in the sea of buzzwords that happen to be popular at any given moment. They ...

Given the current state of quantum computing and the significant challenges that still need to be overcome, it is highly unlikely that a quantum computer that can compromise public-key cryptography – a basis for the security of most of today’s computers and networks – will be built within the next decade, says a new report by the National Academies of Sciences, Engineering, and Medicine.

More and more, customers expect to find cleaner-label options in every aisle of the grocery store, including the bread aisle. Sixty percent of bread consumers say the type of ingredients used in bread formulation is a primary consideration when purchasing.

Nuts, seeds and other inclusions add new dimensions of color, appearance, texture, nutrition, flavor and more to an increasing range of snack and bakery products. Nut and seed consumption has continued to increase over the past several years. One of the contributing factors to the growth is consumer awareness and interest in plant-based foods.

Promoting Equity Without Compromise: Dr. Ryan Smith's Perspective on Fair Grading Practices

Hybrid systems offer a pathway that balances environmental concerns with practical considerations, ensuring a more sustainable and feasible transition towards cleaner energy sources.

On Oct. 21, 1999, the Black Canyon became Colorado's third national park. But it was a painstaking process to get there.

Chorismate mutase (CM), an essential enzyme at the branch-point of the shikimate pathway, is required for the biosynthesis of phenylalanine and tyrosine in bacteria, archaea, plants, and fungi. MtCM, the CM from Mycobacterium tuberculosis, has less than 1% of the catalytic efficiency of a typical natural CM and requires complex formation with 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase for high activity. To explore the full potential of MtCM for catalyzing its native reaction, we applied diverse iterative cycles of mutagenesis and selection, thereby raising kcat/Km 270-fold to 5 × 105 m−1s−1, which is even higher than for the complex. Moreover, the evolutionarily optimized autonomous MtCM, which had 11 of its 90 amino acids exchanged, was stabilized compared with its progenitor, as indicated by a 9 °C increase in melting temperature. The 1.5 Å crystal structure of the top-evolved MtCM variant reveals the molecular underpinnings of this activity boost. Some acquired residues (e.g. Pro52 and Asp55) are conserved in naturally efficient CMs, but most of them lie beyond the active site. Our evolutionary trajectories reached a plateau at the level of the best natural enzymes, suggesting that we have exhausted the potential of MtCM. Taken together, these findings show that the scaffold of MtCM, which naturally evolved for mediocrity to enable inter-enzyme allosteric regulation of the shikimate pathway, is inherently capable of high activity.

The Manitoba government made a "political compromise" in its decision to issue a reduced number of moose hunting licences to non-Indigenous hunters in northern parts of the province earlier this year, a lawyer representing a First Nation in the area has argued in court.

Glyde's specially designed sliding charging station is a great way to charge all your smaller Apple devices.

Charging stations make it easier to get more done with fewer wires, and this one is space-efficient by being retractable. In a way, it's a spiritual successor to the MagSafe Duo, or TwelveSouth's version of the 2-in-1 MagSafe design.

Journey is an Australia-based consumer tech company that specializes in chargers and cases. One of its latest releases is the Glyde 4-in-1 Portable Charging Station.


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It is definitely in the fitness of things that the Supreme Court in a most learned, laudable, landmark, logical and latest judgment titled Ramji Lal Bairwa & Anr vs State of Rajasthan & Ors in Criminal Appeal No. 3403 of 2023 (@ SLP (Crl.) No. 12912 of 2022) and cited in Neutral Citation No.: 2024 I

Title: Is Compromise More Likely When Women Are Part of the Decision?
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM

Russia and Cyprus have announced that they have resolved a dispute concerning the two countries' double tax agreement.

Russia and Cyprus have announced that they have resolved a dispute concerning the two countries' double tax agreement.

medlinkCardiovascular disease/medlink remains one of the leading causes of illness and death in the U.S. and globally. Physicians and researchers

UPS addresses concerns of both employees and the fisc

In this review, we try to find out if the new 2.0-litre petrol engine plonked under the hood of the Range Rover Sport takes downsizing a bit too far for a heavy 'SUV' and if this is worthy of carrying the 'Sport' tag.

Every year for the past 20, Rosa Maria Fuenzalida has visited her mother's grave on Mother's Day without fail in the central Chilean city of Curico.

An excess of secularism may be as problematic as bigotry, whereas pragmatism is in salutary contrast to both of those, writes Ramachandra Guha.

In the capital, Santiago, where the largest cemeteries ordinarily attract tens of thousands of visitors with associated road closures and chaotic scenes, the national federation of cemetery workers this week urged people to stay away.

Given the current state of quantum computing and the significant challenges that still need to be overcome, it is highly unlikely that a quantum computer that can compromise public-key cryptography – a basis for the security of most of today’s computers and networks – will be built within the next decade, says a new report by the National Academies of Sciences, Engineering, and Medicine.

Hackers have hidden malware in a legitimate two-factor authentication (2FA) app for macOS to distribute Dacls, a remote access trojan associated with the North Korean Lazarus group. [...]

Scientists have evaluated two decades of research into declining biodiversity and concluded unequivocally that loss of species richness leads to a reduction in how well ecosystems function. The researchers evaluated the evidence for key biodiversity theories and predicted that scientific progress in the next five to ten years will provide the information we need to efficiently conserve certain ecological processes.

Land-use changes in the arid south-eastern Iberian Peninsula impact on the supply of various ecosystem services that support human well-being. Research into perceptions of the rapid expansion of greenhouse horticulture and the abandonment of rural and mountainous areas has highlighted trade-offs between conservation efforts and economic development.

A lot has changed in American politics in the last year, and a lot has stayed the same.

It's the company's first foray into electrics — a sporty hatchback A3 — and it's coming to the U.S. early next year.

Hyundai's hydrogen-powered Tucson has 265 miles of range, 3-minute fills, and free fuel if you sign a lease now.

John Kerry, former U.S. Secretary of State, shares management and leadership lessons from his long career in public service. He discusses how to win people over to your side, bounce back from defeats, and never give up on your long-term goals. He also calls on private sector CEOs to do more to solve social and political problems. Kerry’s new memoir is "Every Day Is Extra."

Compromised accounts on social networks are regular user accounts that have been taken over by an entity with malicious intent. Since the adversary exploits the already established trust of a compromised account, it is crucial to detect these accounts to limit the damage they can cause. We propose a novel general framework for discovering compromised accounts by semantic analysis of text messages coming out from an account. Our framework is built on the observation that normal users will use language that is measurably different from the language that an adversary would use when the account is compromised. We use our framework to develop specific algorithms that use the difference of language models of users and adversaries as features in a supervised learning setup. Evaluation results show that the proposed framework is effective for discovering compromised accounts on social networks and a KL-divergence-based language model feature works best.

When I heard the news of John Prine's hospitalization on March 30, I was, of course, saddened. His music has meant so much to me over the decades. On that day, I recorded this cover of one of my favorites from Prine's early output, a political song cleverly disguised as a broken-hearted love ballad. There's a video I posted to YouTube of this very same performance, which also includes some spoken introduction, about how I was feeling upon getting the news of John's contracting the coronavirus, and so forth. So, if you'd like to hear that, and see the song performed, it's here. I did a little bit of work on the audio for this MeFiMu upload, though, so I think it might sound a little better here than on the video. Anyway, rest in peace, John Prine, rest in peace.

Eyewear giant Specsavers has admitted that the personal information of some clients in Queensland is missing and may have been stolen.

The Holmes family will continue staying home even after COVID-19 lockdown rules are relaxed — with good reason.

Approximately half of the world’s population is infected with the stomach pathogen Helicobacter pylori. Infection with H. pylori is the main risk factor for distal gastric cancer. Bacterial virulence factors, such as the oncoprotein CagA, augment cancer risk. Yet despite high infection rates, only a fraction of H. pylori–infected individuals develop gastric cancer. This raises the question of defining the specific host and bacterial factors responsible for gastric tumorigenesis. To investigate the tumorigenic determinants, we analyzed gastric tissues from human subjects and animals infected with H. pylori bacteria harboring different CagA status. For laboratory studies, well-defined H. pylori strain B128 and its cancerogenic derivative strain 7.13, as well as various bacterial isogenic mutants were employed. We found that H. pylori compromises key tumor suppressor mechanisms: the host stress and apoptotic responses. Our studies showed that CagA induces phosphorylation of XIAP E3 ubiquitin ligase, which enhances ubiquitination and proteasomal degradation of the host proapoptotic factor Siva1. This process is mediated by the PI3K/Akt pathway. Inhibition of Siva1 by H. pylori increases survival of human cells with damaged DNA. It occurs in a strain-specific manner and is associated with the ability to induce gastric tumor.

An Offer in Compromise is an agreement between the taxpayer and the government that settles a tax liability for payment of less than the full amount owed. The Internal Revenue Service will generally accept an Offer in Compromise when it … Continue reading →

Washington teeters on the brink. If there is no agreement on a budget by midnight on Friday, the federal government will shut down. While cops and soldiers, air traffic controllers and others deemed essential won't down tools this is serious, at least according to the Obama administration. A senior administration official has told us loans to small businesses and home buyers will stop, which will have an impact on an already fragile housing market. Military and civilian workers won't be paid. The lions at the zoo will be fed (and unlike last time their waste should be collected) but the gates won't open to visitors. National parks will close. This is, of course, the most serious, as I am planning a vacation to one of them next week.

I am just back from the Capitol, and talking to people at a Tea Party rally. Their view might be summed up as "bring it on!" They were chanting "Shut it down!" Several made the point that if non-essential parts of the government shut down, they'd be quite happy. If it's not essential, the view is, then the government shouldn't be doing it anyway.

I suspect there will be a deal. There is too much for both sides to lose in the blame game that would follow. But the strength of the Tea Party has already made it hard for their leadership to compromise, and will make selling any deal tough. President Barack Obama and the Democrats don't have quite the same problem but the cuts he has accepted have already upset supporters.

Compromise is a peculiar business, I reflected as I started reading a book called At the Edge of the Precipice, by Robert Remini, the former historian of the US House of Representatives. It is about the 1850 compromise over slavery. He writes that the man at the centre of this, Henry Clay, "understood the importance of compromise... each side must feel that it has gained something that is essential to its interest as the result of the compromise. To achieve that goal each side must surrender something important to the opposing side. Both sides can then claim victory."

His contention is that compromise prevented an early civil war that the North would have lost, having neither leadership nor material to win at that stage. The argument is that it prevented the splitting of the US into two nations and thus was a good move. All history is hindsight, but I am uncertain about praising an agreement on the grounds that it turned out that it came unstuck later with better results. It was hardly the argument at the time. And compromises depend who is at the table. The compromise was between white gentlemen, while the slaves themselves had no say. Perhaps they might have had some thoughts about the value of compromise.

What's this got to do with today's politics? Simply that like Mr Remini, most Americans admire politicians who can behave with dignity and find a way through a difficult problem, by giving and taking. Bipartisanship is one of the highest ideals of US politics. But many of the politicians might question the morality of this. Enough of them might see the matters of practicality and principle at stake as too important to allow the other side to claim any sort of victory.