Atlantic Tire & Service, a locally owned and operated automotive care and repair center with shops in Cary, Raleigh and Durham, NC., was recognized by readers of Cary Magazine as the "Best Mechanic" in Western Wake County.

Detroit Pistons veteran guard Tim Hardaway Jr. was wheelchaired out of the game against the Miami Heat after multiple hits to the head, including slamming it on the court.

Jimmie Tramel wrote an article about KTUL's Plenty Scary Movie in Monday's Tulsa World.

One of the attributed sources for Jimmie Tramel's article.

According to city officials, 87,351 visited on Oct. 31 alone.

The post Salem reports a scary big number of visitors this Halloween season, breaking past records appeared first on Boston.com.

In 60 seconds, the commercial showcases a medley of horror film tropes, including a maniacal doll that presumably kills a group of young people whenever they play a catchy pop song.

Don't be surprised if you see fewer chocolate treats in your trick-or-treating loot. Customers are souring on costly chocolate, resulting from a few disappointing cocoa crop years.

Dr. Caryl J. Guth shared her professional achievements and industry expertise in Golf Digest

Former professor offers individual assistance on a personal basis.

Local general contractor offers deck, patio and porch maintenance services

Carycruz Miriam Bueno, PhD, honored for her expert leadership in economics and education research

As Halloween approaches, it's the perfect time to dive into some spine-chilling content.

Does it seem like there are more spiders around the house right now? And do the spiders you spot seem bigger than those you've seen in recent months? Spider expert, Dr Sara Goodacre, is here with some arachnid answers.

Disney World says Mickey's Not-So-Scary Halloween Party will begin Aug. 11. Tickets go on sale in May.

Amid growing tensions, an employee group is urging DOJ leadership to ramp up its response to online threats many career federal workers continue to face.

The post ‘It’s a scary time’: DOJ employees fear escalation of threats following Election Day first appeared on Federal News Network.

I'm not sure what's more impressive, the Apple's new M3 chips or the fact that the entire was shot using iPhone 15 Pro Maxes. #apple #iphone15promax #scaryfast #mac

A controlled scary experience can leave you exhilarated and relaxed afterward.

Fear is an instinctive, innate biological response that's kept humans safe for many millennia…

The former 'Games of Thrones' actress is adapting the popular 2019 children's book by Christian McKay Heidicker into an animated television mini-series.

What's your favorite scary movie? WEMU's David Fair and Marquee Arts executive director Russ Collins meet up to inform you of tonight's special screenings for your Halloween viewing pleasure! Plus, you'll get details on some new films opening downtown and at the multiplex, too!

Photo by Lisa Zins, via Flickr (https://www.flickr.com/photos/lisazins/)

DirtyOldTown has the most appropriate question for this time of year: What's your favorite scary movie. No, this is not about real life or the US Presidential election, just plain ol' Halloween!

Hosted and executive produced by Wahlberg, eight new episodes reveal extraordinary insight into the twisted crimes committed by some of America's most heinous individuals.

Drop bears are scary right



View Comic!

To #TrumpYourCat, you should brush your pet, then form the hair into a "toupee", and place it on top of their head. Oh, and you can thank Donald Purrump for this genius idea!

And if you need some more Trump memes <-- those are simply tremendous

Have you ever been curious about your monthly water consumption and how it compares to others in your community? Recently, I had this question and decided to get ahold of my family's water usage data for analysis. Harnessing the power of data visualization, I compared my family of four's monthly [...]

The post My Family of Four's Monthly Water Usage (Gallons) Compared to the Town of Cary's Average appeared first on Graphically Speaking.

Title: Simple Steps Make Shots Less Scary for Kids, Nurse Says
Category: Health News
Created: 8/22/2014 12:36:00 PM
Last Editorial Review: 8/25/2014 12:00:00 AM

In the spirit of the Halloween season, IEEE Spectrum presents a pair of stories that—although grounded in scientific truth rather than the macabre—were no less harrowing for those who lived them. In today’s installment, Robert Langer had to push back against his field’s conventional wisdom to pioneer a drug-delivery mechanism vital to modern medicine.

Nicknamed the Edison of Medicine, Robert Langer is one of the world’s most-cited researchers, with over 1,600 published papers, 1,400 patents, and a top-dog role as one of MIT’s nine prestigious Institute Professors. Langer pioneered the now-ubiquitous drug delivery systems used in modern cancer treatments and vaccines, indirectly saving countless lives throughout his 50-year career.

But, much like Edison and other inventors, Langer’s big ideas were initially met with skepticism from the scientific establishment.

He came up in the 1970s as a chemical engineering postdoc working in the lab of Dr. Judah Folkman, a pediatric surgeon at the Boston Children’s Hospital. Langer was tasked with solving what many believed was an impossible problem—isolating angiogenesis inhibitors to halt cancer growth. Folkman’s vision of stopping tumors from forming their own self-sustaining blood vessels was compelling enough, but few believed it possible.

Langer encountered both practical and social challenges before his first breakthrough. One day, a lab technician accidentally spilled six months’ worth of samples onto the floor, forcing him to repeat the painstaking process of dialyzing extracts. Those months of additional work steered Langer’s development of novel microspheres that could deliver large molecules of medicine directly to tumors.

In the 1970s, Langer developed these tiny microspheres to release large molecules through solid materials, a groundbreaking proof-of-concept for drug delivery.Robert Langer

Langer then submitted the discovery to prestigious journals and was invited to speak at a conference in Michigan in 1976. He practiced the 20-minute presentation for weeks, hoping for positive feedback from respected materials scientists. But when he stepped off the podium, a group approached him and said bluntly, “We don’t believe anything you just said.” They insisted that macromolecules were simply too large to pass through solid materials, and his choice of organic solvents would destroy many inputs. Conventional wisdom said so.

Nature published Langer’s paper three months later, demonstrating for the first time that non-inflammatory polymers could enable the sustained release of proteins and other macromolecules. The same year, Science published his isolation mechanism to restrict tumor growth.

Langer and Folkman’s research paved the way for modern drug delivery.MIT and Boston Children’s Hospital

Even with impressive publications, Langer still struggled to secure funding for his work in controlling macromolecule delivery, isolating the first angiogenesis inhibitors, and testing their behavior. His first two grant proposals were rejected on the same day, a devastating blow for a young academic. The reviewers doubted his experience as “just an engineer” who knew nothing about cancer or biology. One colleague tried to cheer him up, saying, “It’s probably good those grants were rejected early in your career. Since you’re not supporting any graduate students, you don’t have to let anyone go.” Langer thought the colleague was probably right, but the rejections still stung.

His patent applications, filed alongside Folkman at the Boston Children’s Hospital, were rejected five years in a row. After all, it’s difficult to prove you’ve got something good if you’re the only one doing it. Langer remembers feeling disappointed but not crushed entirely. Eventually, other scientists cited his findings and expanded upon them, giving Langer and Folkman the validation needed for intellectual property development. As of this writing, the pair’s two studies from 1976 have been cited nearly 2,000 times.

As the head of MIT’s Langer Lab, he often shares these same stories of rejection with early-career students and researchers. He leads a team of over 100 undergrads, grad students, postdoctoral fellows, and visiting scientists, all finding new ways to deliver genetically engineered proteins, DNA, and RNA, among other research areas. Langer’s reputation is further bolstered by the many successful companies he co-founded or advised, like mRNA leader Moderna, which rose to prominence after developing its widely used COVID-19 vaccine.

Langer sometimes thinks back to those early days—the shattered samples, the cold rejections, and the criticism from senior scientists. He maintains that “Conventional wisdom isn’t always correct, and it’s important to never give up—(almost) regardless of what others say.”

The rear of Maini's car was totally destroyed by the impact of the crash and fortunately, he came out of it unscathed

Hart, Caryl, author

[London] : Routledge & Kegan Paul Ltd, 1951.

Montreal : National Film Board of Canada, 2008

Oxford : Privately printed for presentation to the members of The Roxburghe Club, MCMVIII [1908]

Wedding bells?! Here's a new celebrity theory making the internet rounds: fans are convinced that Emma Stone is already married to Saturday Night Live writer, Dave...

Emma Stone (31) has left people convinced that she’s secretly married her beau, Dave McCary(34) after she was spotted wearing what appears to be a wedding band. The pair have been dating for three years and were reportedly forced to cancel their wedding date due to the coronavirus pandemic. Some are convinced the “La La […]

The post Did Emma Stone And Dave McCary Tie The Knot? appeared first on Chart Attack.

Wedding bells?! Here's a new celebrity theory making the internet rounds: fans are convinced that Emma Stone is already married to Saturday Night Live writer, Dave...

Wedding bells?! Here's a new celebrity theory making the internet rounds: fans are convinced that Emma Stone is already married to Saturday Night Live writer, Dave...

Shah Rukh Khan has decided to promote his upcoming production, Betaal, in a fun way. The Badshah of Bollywood is asking fans to channel their inner filmmakers during the lockdown and shoot scary films at home. He announced that winners of

Shah Rukh Khan has decided to promote his upcoming production, Betaal, in a fun way. The Badshah of Bollywood is asking fans to channel their inner filmmakers during the lockdown and shoot scary films at home. He announced that winners of

It stars Viineet Kumar, Aahana Kumra, Suchitra Pillai, Jitendra Joshi, Jatin Goswami, Manjiri Pupala, and Syna Anand, the series will explore age-old secrets and ideologies.

'Betaal': Shah Rukh Khan asks fans to submit scary films, says he...

Finding a fossil is the first step, recognizing it for what it truly is, is the real challenge. While closely studying three fossil skeletons from […]

The post One Scary Chicken—New species of large, feathered dinosaur discovered appeared first on Smithsonian Insider.

This file is in PDF format, requiring the Adobe Acrobat Reader to open.

MNN's lifestyle blogger sent her hair in to get tested for mercury levels — and waited with bated breath to get the results. How would your hair score?

Season Two Reveals Whether Adrienne's Love Life Will Bring Tricks or Treats

A vacuum-assisted in-needle capillary adsorption trap (VA-INCAT) device for sampling and delivering materials to an analytical device is disclosed. A sorbent is multiwall carbon nanotube/polyaniline (PANI/MWCNT) nanocomposite and is coated within an interior space of the needle between the second end and the side aperture to entrap an analyte within a sample. The VA-INCAT device also includes a vacuum device configured to vacuum the vacuum flask to improve the extraction of the analytes vapors from the sample matrix to the sorbent bed.

Nevermind the freaky ghoulish creatures behind the curtains... the music inside will make you a proud Brainiac.

Brainstorm return with a solid effort that takes a step forward in the evolution of their sound while staying true to the Power Metal subgenre.