A protein shredder that occurs in cell membranes of brain cells apparently also indirectly regulates the fat metabolism. This is shown by a recent study by the University of Bonn. The shredder, known as gamma-secretase, is considered a possible target for drugs against cancer and Alzheimer's disease. However, the results suggest that such agents may have long-range effects that need to be watched closely. The study has now been published in "Life Science Alliance".

Its name is Foxg1, it is a gene, and its unprecedented role is the protagonist of the discovery just published on the journal Cerebral Cortex. Foxg1 was already known for being a "master gene" able to coordinate the action of hundreds of other genes. As this new study reports, the "excitability" of neurons, namely their ability to respond to stimuli, communicating between each other and carrying out all their tasks, also depends on this gene.

Researchers have used a microbiome 'fingerprint' method to report that an individualized mosaic of microbial strains is transmitted to the infant gut microbiome from a mother giving birth through vaginal delivery. They detailed this transmission by analyzing existing metagenomic databases of fecal samples from mother-infant pairs, as well as analyzing mouse dam and pup transmission in a germ-free, or gnotobiotic, mouse model, where the dams were inoculated with human fecal microbes.

The report stated that the groups identified are not an exhaustive list of essential employees.

Sixteen migrant workers were crushed to death by a goods train in Aurangabad in Western India.

Saturday is set to be even hotter than Friday.

Reports of interference with aircraft radio communications at one of regional Victoria's busiest airports, where a flying school training pilots for Chinese airlines has been operating for about a year, are being investigated.

Some 70,000 animals across Indonesia, including members of critically endangered species, are at risk of starvation as zoos struggle financially due to social distancing restrictions amid the coronavirus pandemic.

The number of Adelaide rail services has been radically reduced after a mechanical fault, with remaining trains becoming packed with passengers apparently in breach of social distancing.

Joel Prouty, who works with many of New York’s most elite dancers, is in high demand, both because of and despite the coronavirus pandemic.

Certain vitamins, minerals and other supplements can support your immune system as a whole, even though they haven’t been researched for their impact on COVID-19 specifically.

La barre des 10 000 cas par jour serait franchie dès juin en cas d’assouplissement.

The closure of gyms and fitness centres across Australia is taking a massive toll on the industry, but trainers are utilising new apps and running classes online to connect with clients in a bid to remain viable during the coronavirus pandemic.

As pools, gyms and sports facilities shut down to comply with physical-distancing rules, Olympic and Paralympic athletes are coming up with creative ways to ensure their training programs can continue.

Queensland health authorities will consider giving the state's NRL teams the nod to bypass coronavirus restrictions and resume training as the code prepares to restart the season on May 28.

St Kilda's new cult hero Caitlin Greiser is one of 11 first-time selections in the 2020 AFLW All-Australian team after topping the league's goal-kicking chart.

Despite more relaxed coronavirus restrictions in South Australia and Western Australia, the AFL says it does not want clubs from those states training in bigger groups until Victorian teams are allowed to do so.

Albury City Council's decision to block the NRL's Melbourne Storm from using public facilities for training divides both the council and the community.

As the coronavirus keeps us stuck at home, scientists and health officials fear that social distancing could take a toll on our mental health.

A mutation in the novel coronavirus has led to a new strain viewed as more contagious than the virus that emerged from China, according to a new study.

Queens of the Stone Age front man Josh Homme is flipping the script on his estranged wife, whom he claims has been trying to get him busted for allegedly violating a restraining order. Now the rock singer's filed for a restraining order against…

YouTube superstar-turned-fighter Jake Paul says he'll beat the living daylight out of MMA fighter Dillon Danis in a boxing match ... and tells TMZ Sports he has a UFC superstar on board to help him get it done. Of course, Paul previously stated he…

The singer shared a post on Instagram to mark her 32nd birthday, revealing her slimmer frame

Health news and commentary from around the Web gathered by the ALLMedPage Today staff

BrainStorm Cell Therapeutics, a firm developing cellular therapies to tackle neurodegenerative diseases, has named industry Big Pharma veteran Dr David Setboun as its new Executive Vice President and Chief Operating Officer.

Dr Setboun has served for two decades at some of the biggest names in pharma. His most recent role was Vice President of Corporate Development, Strategy & Business at Life Biosciences, where he helped drive development of a range of vital commercial, operating and funding milestones.

read more

Shares of Dr Reddy’s Laboratories rose more than 2% to 3,936.35 rupees, after the Indian drugmaker…

A Chicago police officer pleaded guilty today to violating the federal civil rights of a man whom the officer struck repeatedly with a dangerous weapon while the man was handcuffed and shackled in a wheelchair.

"Helping foreign countries improve their criminal justice systems so they can cooperate more effectively with us and with their neighbors in real time is an important aspect of this department’s mission."

William Cozzi, a Chicago police officer, was sentenced today to 40 months in federal prison for violating the federal civil rights of a man whom the officer struck repeatedly with a dangerous weapon while the man was handcuffed and shackled in a wheelchair.

The Department released a new technical assistance fact sheet on legal requirements relating to admitting individuals with HIV or AIDS to occupational training schools and granting state licensure in occupations such as barbering, massage therapy and home health care assistance.

Deputy Attorney General David W. Ogden today announced plans by the Department of Justice to significantly expand its training and education operations at the National Advocacy Center (NAC), the core training facility for local, state and federal attorneys, law enforcement agents and support personnel.

An indictment unsealed today in Philadelphia charged Omelyan Botsvynyuk, Stepan Botsvynyuk, Mykhaylo Botsvynyuk, Dmytro Botsvynyuk, and Yaroslav Botsvynyuk, a/k/a Yaroslav Churuk, with extortion and conspiracy to violate the Racketeer Influenced and Corrupt Organizations Act (RICO) for their alleged involvement in a human trafficking operation.

"This was a moment in time for the Department of Justice and the Obama administration to send a clear signal that the fight against domestic and sexual violence is a national priority," said Associate Attorney General Perrelli.

The Department of Justice and the Rainbow River Child Development Center of Hawthorne, Calif., have joined in a settlement agreement to assure that children with diabetes will receive appropriate care so that they may participate fully in the programs and activities at the center.

In response to a federal enforcement action for excessive train engine idling, the Massachusetts Bay Transportation Authority (MBTA) and the Massachusetts Bay Commuter Railroad Company (MBCR) will spend more than $2 million to reduce diesel locomotive emissions throughout the MBTA’s commuter rail system.

A former Colombian maritime training instructor and a co-conspirator have pleaded guilty to conspiring to transport thousands of kilograms of cocaine from various ports along the coast of Colombia to waiting vessels that transported the cocaine to the United States and other countries.

The Justice Department has issued letters to the attorneys general of all 50 states, as well as U.S. territories to request their assistance in addressing the illegal exclusion of individuals with HIV/AIDS from occupational training and state licensing.

The Justice Department announced that it has reached an agreement with Jefferson County, Texas, Drainage District Number Seven on the terms of a consent decree filed today in the U.S. District Court for the District of Columbia.

In a settlement valued at more than $1.7 million, Clean Harbors of Braintree Inc. has agreed to pay a significant penalty and perform additional projects, to settle a complaint filed by the U.S. Department of Justice on behalf of the Environmental Protection Agency (EPA), regarding numerous violations of hazardous waste management and emergency planning laws at the company’s Braintree, Mass., facility.

Today, in response to a letter from the Justice Department, the Massachusetts Board of Elementary and Secondary Education voted to grant the Commissioner of Education authority to draft state regulations that will require training of all Sheltered English Immersion teachers who instruct English Language Learner students.

A former Colombian maritime training instructor and a co-conspirator were sentenced to federal prison today for conspiring to transport thousands of kilograms of cocaine from various ports along the coast of Colombia to waiting vessels that transported the cocaine to the United States and other countries.

The Department of Justice’s Bureau of Justice Assistance (BJA), together with its partners, the Departments of Housing and Urban Development (HUD), Education, Health and Human Services and Treasury, today announced the selection of the Center for the Study of Social Policy as the Building Neighborhood Capacity Program (BNCP) Training and Technical Assistance Coordinator.

The Justice Department announced a settlement today with Lorain County, Ohio, to protect the rights of Spanish-speaking Puerto Rican voters under Section 4(e) of the Voting Rights Act.

Federal officials announced a civil settlement with the state of California Department of Transportation (Caltrans) resolving claims brought by the Presidio Trust and the U.S. Army resulting from Caltrans’ construction and operation of Highway 1 (also known as Park Presidio Boulevard) through the Presidio of San Francisco.

Former Tuscaloosa, Ala., Sheriff’s Sergeant, Althea Mallisham, 52, pleaded guilty today in a federal court in Birmingham, Ala., to three counts of assault with a dangerous weapon while acting under color of law for wrongfully using a Taser during three separate incidents over a four month period in 2008.

The Justice and Interior Departments today completed the first in a series of national level training courses, “Criminal Jurisdiction in Indian Country” (CJIC), designed to strengthen the ability of tribal and local law enforcement to participate in the investigation and enforcement of federal crimes in Indian country and fulfill a key training requirement under the Tribal Law and Order Act of 2010 (TLOA).

"There are parts of the world where everyone shares the same culture, the same religion, and the same language. But that’s not America. And it’s not Cincinnati. According to the Census Bureau, there are over 13,000 people in this city who were born outside of the United States. There are around 20,000 whose primary language isn’t English. And there are still more who follow customs and traditions that our own upbringing didn’t expose us to," said Deputy Attorney General Cole.