cla Episode 60 - The Internet of post-Easter nerds (IoPEN) F8, Mac Pro and RIP NES Classic By play.acast.com Published On :: Fri, 21 Apr 2017 09:45:58 GMT Back with a bumper edition after the Easter break, as Henry Burrell takes Scott Carey, David Price and Dom Preston on a chat odyssey to discuss Facebook's F8 conference. Will chat bots ever be good and who uses QR codes? The gang then discusses Apple's out of character decision to brief journos on the Mac Pro and even admit they got it wrong. Finally we talk about Nintendo stopping production of the NES Classic and whether there's more affordable retro goodness around the corner. See acast.com/privacy for privacy and opt-out information. Full Article pod podcast tech technology chat nintendo apple mac pro imac funny podcast
cla WITHDRAWN: Structural and mechanistic studies of hydroperoxide conversions catalyzed by a CYP74 clan epoxy alcohol synthase from amphioxus (Branchiostoma floridae) [Research Articles] By feedproxy.google.com Published On :: 2014-03-04T09:59:12-08:00 This manuscript has been withdrawn by the Author. Full Article
cla LDL subclass lipidomics in atherogenic dyslipidemia:Effect of statin therapy on bioactive lipids and dense LDL [Patient-Oriented and Epidemiological Research] By feedproxy.google.com Published On :: 2020-04-15T11:30:30-07:00 Atherogenic LDL particles are physicochemically and metabolically heterogeneous. Can bioactive lipid cargo differentiate LDL subclasses, and thus potential atherogenicity? What is the effect of statin treatment? Obese, hypertriglyceridemic, hypercholesterolemic males (n=12; Lp(a) <10 mg/dL) received pitavastatin calcium (4mg/day) for 180 days in a single-phase, unblinded study. The lipidomic profiles (23 lipid classes) of five LDL subclasses fractionated from baseline and post-statin plasmas were determined by LC-MS. At baseline and on statin treatment, very small dense LDL (LDL5) was preferentially enriched (up to 3-fold) in specific lysophospholipids (lysophosphatidylcholine (LPC); lysophosphatidylinositol (LPI); lyso-platelet activating factor (LPC(O)); 9,0.2 and 0.14 mol/mol apoB respectively; all p<0.001 versus LDL1-4), suggesting elevated inflammatory potential per particle. In contrast, lysophosphatidylethanolamine was uniformly distributed among LDL subclasses. Statin treatment markedly reduced absolute plasma concentrations of all LDL subclasses (up to 33.5%), including LPC, LPI and LPC(O) contents (up to -52%), consistent with reduction in cardiovascular risk. Despite such reductions, lipotoxic ceramide load per particle in LDL1-5 (1.5 - 3 mol/mol apoB; 3 - 7 mmol/mol phosphatidylcholine) was either conserved or elevated. Bioactive lipids may constitute biomarkers for the cardiometabolic risk associated with specific LDL subclasses in atherogenic dyslipidemia at baseline, and with residual risk on statin therapy. Full Article
cla Lithium ion adduction enables UPLC-MS/MS-based analysis of multi-class 3-hydroxyl group-containing keto-steroids [Methods] By feedproxy.google.com Published On :: 2020-04-01T00:05:29-07:00 Steroids that contain a 3-hydroxyl group (3-OH steroids) are widely distributed in nature. During analysis with ESI-MS, they easily become dehydrated while in the protonated form, resulting in the production of several precursor ions and leading to low sensitivity of detection. To address this analytical challenge, here, we developed a method for the quantitation of 3-OH steroids by LC-MS/MS coupled with post-column addition of lithium (Li) ions to the mobile phase. The Li ion has a high affinity for the keto group of steroids, stabilizing their structures during ionization and permitting detection of analytes exclusively as the lithiated form. This not only improved the intensities of the precursor ions, but also promoted the formation of typical lithiated fragment ions. This improvement made the quantitation by multiple reaction monitoring more sensitive and reliable, as evidenced by 1.53–188 times enhanced detection sensitivity of 13 steroids that contained at least one keto and two hydroxyl groups or one keto and one 5-olefinic double bond, among 16 different 3-OH steroids. We deployed our newly developed method for profiling steroids in mouse brain tissue and identified six steroids in one tissue sample. Among these, 16-hydroxyestrone, tetrahydrocorticosterone, and 17α-hydroxypregnenolone were detected for the first time in the mouse brain. In summary, the method described here enables the detection of lithiated steroids by LC-MS/MS, including three 3-OH steroids not previously reported in the mouse brain. We anticipate that this new method may allow the determination of 3-OH steroids in different brain regions. Full Article
cla Problem Notes for SAS®9 - 65682: Running FedSQL with an Oracle table is slow, even when you use a LIMIT clause By feedproxy.google.com Published On :: Fri, 1 May 2020 14:43:59 EST When you query an Oracle table and use the LIMIT clause using either SAS Federation Server or FedSQL, a row limit is not passed to the database. In this scenario, a Full Article DFFEDSVR+SAS+Federation+Server
cla Problem Notes for SAS®9 - 65597: An SQL procedure query with a WHERE clause that contains multiple subselects might return incorrect results By feedproxy.google.com Published On :: Tue, 28 Apr 2020 12:37:41 EST An issue occurs when code contains a complex SQL procedure query with a WHERE clause that contains multiple subselects. Incorrect results might be returned. Click the Hot Fix tab in this note to Full Article BASE+Base+SAS
cla Female athletes need more recognition – Clayton By jamaica-gleaner.com Published On :: Fri, 08 May 2020 00:23:08 -0500 National 400m hurdles champion Rushell Clayton is concerned about what she says are inequalities between men and women in track and field. Clayton was speaking at a Women in Sports Conference in Kingston recently and discussed issues of inequality... Full Article
cla Michelle Sinclair GP - surgery buildings are not up to scratch By feeds.bmj.com Published On :: Fri, 13 Feb 2015 16:17:25 +0000 Michelle Sinclar, a GP in Hampshire who is concerned that GP premises aren't fit for purpose and limit her ability to provide fully rounded patient care. BMJ Voices is a collection of readers’ experiences of working in the NHS. For this, The BMJ is seeking short audio submissions from UK listeners. These submissions will be published on... Full Article
cla Exercise in old age - "we need kendo classes in Huddersfield" By feeds.bmj.com Published On :: Wed, 18 Oct 2017 16:24:10 +0000 There's a crisis in old age care - not just in the UK, around the world, as population demographics shift, and the proportion of older people increase - there's a worry about who's going to look after them, and how much is it going to cost? However, a new analysis on bmj.com says this picture need not be so gloomy - they say that encouraging... Full Article
cla From dance class to social prescription - starting and evaluating an idea By feeds.bmj.com Published On :: Tue, 07 Jan 2020 10:47:03 +0000 If you read the Christmas BMJ in the last few weeks, you might have noticed a lot around art and health - the way in which engagement in arts can help in prevention and treatment, but can also affect those more nebulous things which really matter to patients - loneliness, self expression, being connected to the wider community. That obviously... Full Article
cla Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance By diabetes.diabetesjournals.org Published On :: 1979-12-01 National Diabetes Data GroupDec 1, 1979; 28:1039-1057Articles Full Article
cla Reply: Clarifying the Utility of Myocardial Blood Flow and Myocardial Flow Reserve After Cardiac Transplantation By jnm.snmjournals.org Published On :: 2020-04-01T06:00:28-07:00 Full Article
cla Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies By feeds.bmj.com Published On :: Wednesday, March 25, 2020 - 22:30 Full Article
cla Prospective registration and reporting of trial number in randomised clinical trials: global cross sectional study of the adoption of ICMJE and Declaration of Helsinki recommendations By feeds.bmj.com Published On :: Tuesday, April 14, 2020 - 09:20 Full Article
cla Leadership Visions: A Discussion with Mexican Foreign Minister Claudia Ruiz-Massieu By www.migrationpolicy.org Published On :: Mon, 30 Nov 2015 21:16:58 -0500 An MPI Leadership Visions discussion with the Foreign Minister of Mexico, Claudia Ruiz-Massieu, for her first public appearance in Washington, DC. Full Article
cla International Classification of Diseases, 10th Revision, Coding for Diabetes By clinical.diabetesjournals.org Published On :: 2017-10-01 Joy DuganOct 1, 2017; 35:232-238Practical Pointers Full Article
cla A Review of the Pathophysiology, Classification, and Treatment of Foot Ulcers in Diabetic Patients By clinical.diabetesjournals.org Published On :: 2009-03-01 Warren ClaytonMar 1, 2009; 27:52-58Features Full Article
cla Watch: Utah man reunited with class ring 38 years after it was lost in Germany By www.upi.com Published On :: Thu, 07 May 2020 15:42:56 -0400 A Utah man who lost his high school class ring in Germany in 1982 was reunited with the ring thanks to a man who found it on a beach in the United States. Full Article
cla Phishing email claims to be from ADA president By www.ada.org Published On :: Mon, 02 Mar 2020 17:04:00 -0600 At least one American Dental Association member has reported receiving a phishing email appearing to come from an address containing ADA President Chad P. Gehani's name and including a link to "view member's details." Full Article
cla ADA seeks clarification from HHS regarding chief dental officer By www.ada.org Published On :: Fri, 06 Mar 2020 14:50:00 -0600 The American Dental Association is applauding the U.S. Department of Health and Human Services’ decision to appoint a chief dental officer at the Centers for Medicare & Medicaid but would like to confirm the position is exclusive to CMS. Full Article
cla Study: Evidence does not support classifying fluoride as cognitive neurodevelopmental hazard By www.ada.org Published On :: Tue, 10 Mar 2020 09:53:00 -0500 The National Academies of Sciences, Engineering, and Medicine announced March 5 that it does not find that the National Toxicology Program adequately supported its conclusion that fluoride is “presumed” to be a cognitive neurodevelopmental hazard to humans. Full Article
cla ADA asks Treasury Department, Small Business Administration to clarify intent of interim rule By www.ada.org Published On :: Sun, 05 Apr 2020 11:09:00 -0500 The Association continues to wait for clear guidance from the U.S. Department of Treasury and Small Business Administration on the best way to help dentists considering applying for Paycheck Protection Program 7(a) loans and Economic Injury Disaster Loans. Full Article
cla UCLA dental school researchers create nanoparticle that could improve bone defect treatment By www.ada.org Published On :: Tue, 05 May 2020 10:25:00 -0500 A team of researchers at the University of California, Los Angeles School of Dentistry has developed a nanoparticle that could improve treatment for bone defects. Full Article
cla Classroom Observations By schoolpsychologistfiles.blogspot.com Published On :: Mon, 02 Nov 2009 01:28:00 +0000 Classroom observations occur to document behaviors and to help provide insight to teachers. Teachers are teaching and are typically focused on the overall learning of the entire class. It is not possible for a teacher to catch all of the details of classroom while teaching. An outside observer, often a School Psychologist, can sit in the classroom and observe a student or the entire class. These insights can be used to help provide better instruction, create behavioral or academic interventions, or to document behaviors. When do classroom observations occur? - During a special education evaluation The classroom observation is a required component in a special education evaluation. It provides data and insight to the eligibility committee. - Before a Behavior Intervention Plan or Functional Behavioral Assessment Classroom observations are important before implementing a Functional Behavioral Assessment or a Behavior Intervention Plan. It helps to clarify the current behaviors, identify possible triggers of the behavior, and determine the frequency of the behaviors. - When a teacher is worried about a particular student Often a teacher will have a concern about a student and ask the School Psychologist to conduct an observation. After the observation the teacher and psychologist will meet to discuss and brainstorm strategies to assist in instruction. Full Article Interventions
cla Leadership Visions: A Discussion with Mexican Foreign Minister Claudia Ruiz-Massieu By www.migrationpolicy.org Published On :: Tue, 15 Dec 2015 11:41:39 -0500 An MPI Leadership Visions discussion with the Foreign Minister of Mexico, Claudia Ruiz-Massieu, for her first public appearance in Washington, DC. Full Article
cla 'Valley Girl' musical reinvents classic '80s music By www.upi.com Published On :: Fri, 08 May 2020 03:00:08 -0400 Director Rachel Lee Goldenberg discusses how her "Valley Girl" musical remake puts a twist on the hit music of the '80s. Full Article
cla Watch: Kelly Clarkson on 'chaos' of filming 'The Voice' remotely By www.upi.com Published On :: Fri, 08 May 2020 10:21:55 -0400 Kelly Clarkson discussed the challenges of filming "The Voice" at home amid the coronavirus pandemic. Full Article
cla CBS orders first seasons of 'Clarice,' 'Equalizer,' 'B Positive' for 2020-21 By www.upi.com Published On :: Sat, 09 May 2020 11:08:24 -0400 CBS said it has ordered first seasons of three new shows -- "Clarice," "The Equalizer" and "B Positive" for the 2020-21 television season. Full Article
cla Confessions Not Always Clad in Iron By www.washingtonpost.com Published On :: Mon, 01 Oct 2007 00:00:00 EDT In the courts and in Congress, Sen. Larry Craig is fighting to withdraw his guilty plea to a misdemeanor charge that may suggest he tried to solicit sex from a man in June at a Minneapolis airport bathroom. Rather than resign yesterday, as the senator had promised and Republicans had hoped, Craig... Full Article Opinions Confessions Not Always Clad in Iron
cla Effectively Serving Children in a Superdiverse Classroom: Implications for the Early Education System By www.migrationpolicy.org Published On :: Thu, 22 Feb 2018 17:29:16 -0500 As the number and share of Dual Language Learners (DLLs) continues to grow across the United States, diversity within this population is also increasing. This webinar marks the release of a report providing analysis of the diversity within the DLL population nationwide and at the state and local levels. Speakers discuss data on the three rapidly growing subgroups within the DLL population: Black and Asian American and Pacific Islander DLLs and young children of refugees, and the implications for the early education and care field and K-12 education systems. Full Article
cla Citrus cured salmon, pickled clams, herb emulsion By www.abc.net.au Published On :: Tue, 19 Jul 2016 14:28:00 +1000 This recipe features on Foodie Tuesday, a weekly segment on 774 Drive with Raf Epstein, 3.30PM, courtesy of David Hall of Pure South Dining. Full Article ABC Local melbourne Lifestyle and Leisure:Recipes:Main Australia:VIC:Melbourne 3000
cla Chilli Clams with Zucchini Pasta By www.abc.net.au Published On :: Tue, 31 Jan 2017 13:42:00 +1100 Alice Zaslavsky, shared this recipe on Foodie Tuesday, a weekly segment on ABC Radio Melbourne's Drive program at 3.30pm. Full Article ABC Local melbourne Lifestyle and Leisure:Recipes:All Australia:VIC:Melbourne 3000
cla Efficacy and Safety of Dapagliflozin in the Elderly: Analysis From the DECLARE-TIMI 58 Study By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE Data regarding the effects of sodium–glucose cotransporter 2 inhibitors in the elderly (age ≥65 years) and very elderly (age ≥75 years) are limited. RESEARCH DESIGN AND METHODS The Dapagliflozin Effect on Cardiovascular Events (DECLARE)–TIMI 58 assessed cardiac and renal outcomes of dapagliflozin versus placebo in patients with type 2 diabetes. Efficacy and safety outcomes were studied within age subgroups for treatment effect and age-based treatment interaction. RESULTS Of the 17,160 patients, 9,253 were <65 years of age, 6,811 ≥65 to <75 years, and 1,096 ≥75 years. Dapagliflozin reduced the composite of cardiovascular death or hospitalization for heart failure consistently, with a hazard ratio (HR) of 0.88 (95% CI 0.72, 1.07), 0.77 (0.63, 0.94), and 0.94 (0.65, 1.36) in age-groups <65, ≥65 to <75, and ≥75 years, respectively (interaction P value 0.5277). Overall, dapagliflozin did not significantly decrease the rates of major adverse cardiovascular events, with HR 0.93 (95% CI 0.81, 1.08), 0.97 (0.83, 1.13), and 0.84 (0.61, 1.15) in age-groups <65, ≥65 to <75, and ≥75 years, respectively (interaction P value 0.7352). The relative risk reduction for the secondary prespecified cardiorenal composite outcome ranged from 18% to 28% in the different age-groups with no heterogeneity. Major hypoglycemia was less frequent with dapagliflozin versus placebo, with HR 0.97 (95% CI 0.58, 1.64), 0.50 (0.29, 0.84), and 0.68 (0.29, 1.57) in age-groups <65, ≥65 to <75, and ≥75 years, respectively (interaction P value 0.2107). Safety outcomes, including fractures, volume depletion, cancer, urinary tract infections, and amputations were balanced with dapagliflozin versus placebo, and acute kidney injury was reduced, all regardless of age. Genital infections that were serious or led to discontinuation of the study drug and diabetic ketoacidosis were uncommon, yet more frequent with dapagliflozin versus placebo, without heterogeneity (interaction P values 0.1058 and 0.8433, respectively). CONCLUSIONS The overall efficacy and safety of dapagliflozin are consistent regardless of age. Full Article
cla Clarifying the Role of Insulin in Type 2 Diabetes Management By clinical.diabetesjournals.org Published On :: 2003-01-01 John R. WhiteJan 1, 2003; 21:Feature Articles Full Article
cla People Who Have Lost Their Religion Show “Residues” Of Religious Past In Their Thoughts And Behaviours, Study Claims By feedproxy.google.com Published On :: Thu, 07 May 2020 11:17:52 +0000 By Emma Young. Formerly religious are more prosocial than those who were never religious, researchers argue. Full Article Religion Social
cla A RedForEd Wave: Teachers in North and South Carolina Leave Classrooms in Protest By feedproxy.google.com Published On :: Wed, 01 May 2019 00:00:00 +0000 A sea of red swept the capitals of North and South Carolina on Wednesday, as thousands of teachers turned out to demand higher pay and more school funding. Full Article North_Carolina
cla LeBron James to honor Class of 2020 with all-star event By feedproxy.google.com Published On :: 2020-04-29T23:59:33-04:00 Full Article Education
cla Unimpressed by online classes, college students seek refunds By feedproxy.google.com Published On :: 2020-05-04T05:22:11-04:00 Full Article Education
cla Stop Giving Inexperienced Teachers All the Lower-Level Math Classes, Reformers Argue By feedproxy.google.com Published On :: 2020-05-06T00:00:00-04:00 “Detracking” math teachers is tough because many educators resist upending their routines or challenging informal hierarchies, and PD initiatives to make it happen are limited. Full Article Education
cla Lamont canceling in-person classes for rest of school year By feedproxy.google.com Published On :: 2020-05-05T23:44:20-04:00 Full Article Education
cla Public schools, classes at Univ. of SC hope for fall return By feedproxy.google.com Published On :: 2020-05-06T17:56:54-04:00 Full Article Education
cla Montana unemployment claims decrease, some schools reopen By feedproxy.google.com Published On :: 2020-05-07T17:54:27-04:00 Full Article Education
cla Clark County School District postpones graduation ceremonies By feedproxy.google.com Published On :: Mon, 20 Apr 2020 00:00:00 +0000 Full Article Nevada
cla Sharing Services Offers Cost Savings and Better Service, Claims N.Y. Survey By feedproxy.google.com Published On :: Tue, 11 Mar 2014 00:00:00 +0000 New York superintendents who shared services reported more cost savings and improved service quality than improved student achievement, according to a new research brief. Full Article New_York
cla Tennessee School District Prohibits Crowdfunding for Class Supplies By feedproxy.google.com Published On :: Wed, 20 Mar 2019 00:00:00 +0000 A school district in Tennessee says it no longer wants teachers to use crowdfunding websites to get extra school supplies. Full Article Tennessee
cla LeBron James to honor Class of 2020 with all-star event By feedproxy.google.com Published On :: 2020-04-30T08:46:11-04:00 Full Article Education
cla Unimpressed by online classes, college students seek refunds By feedproxy.google.com Published On :: 2020-05-04T08:41:25-04:00 Full Article Education
cla Stop Giving Inexperienced Teachers All the Lower-Level Math Classes, Reformers Argue By feedproxy.google.com Published On :: 2020-05-05T16:26:10-04:00 “Detracking” math teachers is tough because many educators resist upending their routines or challenging informal hierarchies, and PD initiatives to make it happen are limited. Full Article Education
cla Lamont canceling in-person classes for rest of school year By feedproxy.google.com Published On :: 2020-05-06T08:43:51-04:00 Full Article Education
cla Public schools, classes at Univ. of SC hope for fall return By feedproxy.google.com Published On :: 2020-05-06T15:18:38-04:00 Full Article Education