ux Need for Speed Heat Deluxe Edition XBOX-$6.99 By www.cheapassgamer.com Published On :: Tue, 17 Oct 2023 08:12:05 +0000 Need for Speed Heat Deluxe Edition XBOX-$6.99 Full Article
ux The $20 IKEA Bedside Table That Became a Luxury Sideboard By ikeahackers.net Published On :: Tue, 05 Nov 2024 11:00:00 +0000 My search for the perfect sideboard has been going on for like ever. Like many home decor enthusiasts, I found myself caught between my champagne taste and lemonade budget – until I came across @interiorxlifestyle‘s IKEA hack. She transformed the affordable IKEA GURSKEN nightstands into a sophisticated storage sideboard that may just be the thing I’m looking for. On its own, a single hacked GURSKEN might not amount to much. But when you place five of these hacked beauties in […] The post The $20 IKEA Bedside Table That Became a Luxury Sideboard appeared first on IKEA Hackers. Full Article Cabinets & Sideboards Gursken Latest on IG
ux Luxury Bel-Air hilltop home is an energy-efficient dream By inhabitat.com Published On :: Wed, 05 Jul 2023 18:30:00 +0000 RO54 is a split-level modern home perched on a Bel-Air hilltop. But this is not what your mind probably conjures when you think of a split-level home. RO54 by Arshia Architects is a dreamy façade of floating glass with view of the Pacific Ocean, designed in layers to allow a gradual ascent to the top of the roof with little effort.[...] Full Article Homes natural light California green buildings rainwater filtration post-format-gallery home d
ux New CRON#TRAP Malware Infects Windows by Hiding in Linux VM to Evade Antivirus By thehackernews.com Published On :: Fri, 08 Nov 2024 12:45:00 +0530 Cybersecurity researchers have flagged a new malware campaign that infects Windows systems with a Linux virtual instance containing a backdoor capable of establishing remote access to the compromised hosts. The "intriguing" campaign, codenamed CRON#TRAP, starts with a malicious Windows shortcut (LNK) file likely distributed in the form of a ZIP archive via a phishing email. "What makes the CRON# Full Article
ux Lost World Deluxe Digital Download By craigjparker.blogspot.com Published On :: Thu, 07 Nov 2024 11:30:00 +0000 Update: Now available in the UK store too, but only until midnight tonight (Nov. 7th).It's now available in the EU and AU shops as well.Available from The Cure shop (US only, but there are ways around that):THE CURE SONGS OF A LOST WORLD (DELUXE) DIGITAL DOWNLOAD (MP3 & FLAC)US $4.99DELUXE DIGITAL ALBUM FEATURES SONGS OF A LOST WORLD STANDARD TRACKLIST PLUS FIVE LIVE BONUS TRACKS RECORDED AT SHORELINE AMPHITHEATER IN 2023.TRACKLIST:1.ALONE2.AND NOTHING IS FOREVER3.A FRAGILE THING4.WARSONG5.DRONE:NODRONE6.I CAN NEVER SAY GOODBYE7.ALL I EVER AM8.ENDSONG9.ALONE : LIVE @ SHORELINE AMPHITHEATER 202310.AND NOTHING IS FOREVER : LIVE @ SHORELINE AMPHITHEATER 202311.A FRAGILE THING : LIVE @ SHORELINE AMPHITHEATER 202312.I CAN NEVER SAY GOODBYE : LIVE @ SHORELINE AMPHITHEATER 202313.ENDSONG : LIVE @ SHORELINE AMPHITHEATER 2023LIVE @ SHORELINE AMPHITHEATER 2023 Full Article
ux The best luxury hotels in the Cotswolds By www.telegraph.co.uk Published On :: Tue, 22 Oct 2024 16:30:00 GMT Full Article topics:places/cotswolds topics:places/europe travel-entity:article structure:travel/hotels topics:places/united-kingdom topics:places/england structure:travel storytype:standard structure:travel/top-10-hotels structure:hotel-guides structure:us-content structure:eg-general structure:better-life/better-life-evergreen structure:better-life/better-life-guide
ux Dear Life Kit: Is it a faux pas to create a 'happy graduation' registry for myself? By www.npr.org Published On :: Thu, 31 Oct 2024 10:00:08 -0400 An NPR listener is graduating soon with her MBA. She wants to know if it's OK celebrate her achievement by asking loved ones to buy her gifts from a registry, similar to what people do for weddings. Full Article
ux Why luxury cheese is being targeted by black market criminals By www.bbc.com Published On :: Sun, 10 Nov 2024 08:58:48 GMT How cheese has become so valuable that it's being stolen to order Full Article
ux We got married at a luxury resort in Thailand. If I could go back, there are 5 things I'd do differently. By www.businessinsider.com Published On :: Wed, 13 Nov 2024 00:14:01 +0000 Looking back, Ellie Furuya says her wedding reception in Thailand was too adult-centric. If she could go back, she'd make it more kid-friendly. Full Article Health Travel as-told-to singapore-freelancer destination-weddings thailand weddings phuket
ux luxuriantbliss763.yolasite.com By luxuriantbliss763.yolasite.com Published On :: Sun, 26 Mar 2017 11:51:32 +0000 The mobile phone market is teeming with a large number of brands, which have been capable of gaining worldwide recognition. Similar to other, this market is also witnessing fiercely competitive scenario. Full Article
ux A.F. Branco Cartoon – Costume Faux Pas By comicallyincorrect.com Published On :: Tue, 29 Oct 2024 12:00:58 +0000 A.F. Branco Cartoon – Mainstream leftist media, along with the Democrats (The Party of the KKK), are trying their best.. Full Article Political Cartoons
ux Cell cholesterol efflux: integration of old and new observations provides new insights By www.jlr.org Published On :: 1999-05-01 George H. RothblatMay 1, 1999; 40:781-796Reviews Full Article
ux Structure dynamics of ApoA-I amyloidogenic variants in small HDL increase their ability to mediate cholesterol efflux By www.jlr.org Published On :: 2020-11-17 Oktawia NilssonNov 17, 2020; 0:jlr.RA120000920v1-jlr.RA120000920Research Articles Full Article
ux High-density lipoprotein-associated miRNA is increased following Roux-en-Y gastric bypass surgery for severe obesity [Research Articles] By www.jlr.org Published On :: 2020-10-22T06:30:32-07:00 Roux-en-Y gastric bypass (RYGB) is one of the most commonly performed weight-loss procedures, but how severe obesity and RYGB affects circulating HDL-associated microRNAs (miRNAs) remains unclear. Here, we aim to investigate how HDL-associated miRNAs are regulated in severe obesity and how weight loss after RYGB surgery affects HDL-miRNAs. Plasma HDL were isolated from patients with severe obesity (n=53) before, 6 and 12 months after RYGB by immunoprecipitation using goat anti-human apoA-I microbeads. HDL were also isolated from 18 healthy participants. miRNAs were extracted from isolated HDL and levels of miR-24, miR-126, miR-222 and miR-223 were determined by TaqMan miRNA assays. We found that HDL-associated miR-126, miR-222 and miR-223 levels, but not miR-24 levels, were significantly higher in patients with severe obesity when compared with healthy controls. There were significant increases in HDL-associated miR-24, miR-222 and miR-223 at 12 months after RYGB. Additionally, cholesterol efflux capacity and paraoxonase (PON1) activity were increased and intracellular adhesion molecule-1 (ICAM-1) levels decreased. The increases in HDL-associated miR-24 and miR-223 were positively correlated with increase in cholesterol efflux capacity (r=0.326, P=0.027 and r=0.349, P=0.017 respectively). An inverse correlation was observed between HDL-associated miR-223 and ICAM-1 at baseline. Together, these findings show that HDL-associated miRNAs are differentially regulated in healthy versus patients with severe obesity and are altered after RYGB. These findings provide insights into how miRNAs are regulated in obesity before and after weight reduction, and may lead to the development of novel treatment strategies for obesity and related metabolic disorders. Full Article
ux Structure dynamics of ApoA-I amyloidogenic variants in small HDL increase their ability to mediate cholesterol efflux [Research Articles] By www.jlr.org Published On :: 2020-11-17T08:30:36-08:00 Apolipoprotein A-I (ApoA-I) of high-density lipoprotein (HDL) is essential for the transportation of cholesterol between peripheral tissues and the liver. However, specific mutations in Apolipoprotein A-I (ApoA-I) of high-density lipoprotein (HDL) are responsible for a late-onset systemic amyloidosis, the pathological accumulation of protein fibrils in tissues and organs. Carriers of these mutations do not exhibit increased cardiovascular disease risk despite displaying reduced levels of ApoA-I/ HDL-cholesterol. To explain this paradox, we show that the HDL particle profile of patients carrying either L75P or L174S ApoA-I amyloidogenic variants a higher relative abundance of the 8.4 nm vs 9.6 nm particles, and that serum from patients, as well as reconstituted 8.4 and 9.6 nm HDL particles (rHDL), possess increased capacity to catalyze cholesterol efflux from macrophages. Synchrotron radiation circular dichroism and hydrogen-deuterium exchange revealed that the variants in 8.4 nm rHDL have altered secondary structure composition and display a more flexible binding to lipids compared to their native counterpart. The reduced HDL-cholesterol levels of patients carrying ApoA-I amyloidogenic variants are thus balanced by higher proportion of small, dense HDL particles and better cholesterol efflux due to altered, region-specific protein structure dynamics. Full Article
ux Different rates of flux through the biosynthetic pathway for long-chain versus very-long-chain sphingolipids [Research Articles] By www.jlr.org Published On :: 2020-10-01T00:05:17-07:00 The backbone of all sphingolipids (SLs) is a sphingoid long-chain base (LCB) to which a fatty acid is N-acylated. Considerable variability exists in the chain length and degree of saturation of both of these hydrophobic chains, and recent work has implicated ceramides with different LCBs and N-acyl chains in distinct biological processes; moreover, they may play different roles in disease states and possibly even act as prognostic markers. We now demonstrate that the half-life, or turnover rate, of ceramides containing diverse N-acyl chains is different. By means of a pulse-labeling protocol using stable-isotope, deuterated free fatty acids, and following their incorporation into ceramide and downstream SLs, we show that very-long-chain (VLC) ceramides containing C24:0 or C24:1 fatty acids turn over much more rapidly than long-chain (LC) ceramides containing C16:0 or C18:0 fatty acids due to the more rapid metabolism of the former into VLC sphingomyelin and VLC hexosylceramide. In contrast, d16:1 and d18:1 ceramides show similar rates of turnover, indicating that the length of the sphingoid LCB does not influence the flux of ceramides through the biosynthetic pathway. Together, these data demonstrate that the N-acyl chain length of SLs may not only affect membrane biophysical properties but also influence the rate of metabolism of SLs so as to regulate their levels and perhaps their biological functions. Full Article
ux Quelle est la meilleure recette minceur à base de biscuits aux flocons d’avoine ? By www.orthodfr.org Published On :: Thu, 26 Sep 2024 13:34:24 +0000 Pour beaucoup de personnes, la perte de poids rime obligatoirement avec une période de privation. Mais contrairement à ces idées reçues, il est bien possible d’observer un régime pour perdre du poids tout en vous faisant plaisir. Découvrez notre recette minceur de biscuits croquants sans beurre aux flocons d’avoine qui raviront vos papilles sans pour autant vous apporter […] L’article Quelle est la meilleure recette minceur à base de biscuits aux flocons d’avoine ? est apparu en premier sur Ortho Doc France. Full Article Minceur
ux AlmaLinux OS Foundation Chair to Discuss Embracing Diversity in Open Source at SC24 By www.hpcwire.com Published On :: Thu, 07 Nov 2024 14:00:42 +0000 FORT MYERS, Fla., Nov. 7, 2024 — The AlmaLinux OS Foundation, the nonprofit that stewards the free and community-governed open source enterprise Linux distribution, today announced that chair benny Vasquez is […] The post AlmaLinux OS Foundation Chair to Discuss Embracing Diversity in Open Source at SC24 appeared first on HPCwire. Full Article
ux Luxury, not landfill — the waste-free future of fashion | Joon Silverstein By www.ted.com Published On :: Mon, 04 Nov 2024 16:00:36 +0000 Fashion is a huge part of the world's waste problem, but it doesn't have to be. Coachtopia founder Joon Silverstein shows how her company creates new designs from the waste products of another, a circular process that cuts the need for new raw materials — and rethinks what qualifies as "luxury." (Made in partnership with Coachtopia) Full Article Higher Education
ux How We See Oppenheimer (redux) By www.smithsonianmag.com Published On :: Thu, 31 Oct 2024 00:00:00 -0000 Christopher Nolan's epic new film "Oppenheimer" is no mere biopic… nor is it the first attempt to capture the father of the atomic bomb in fiction. We look at prior dramatizations of this very complicated man—including one wherein J. Robert Oppenheimer played himself!—and examine why they worked or didn't. In this episode: Physicist-turned-photographer Minesh Bacrania shares his experience photographing inside the top-secret labs at Los Alamos National Laboratory, where J. Robert Oppenheimer and other scientists created the first nuclear weapon. Next, with Christopher Nolan’s film Oppenheimer exceeding commercial expectations, Smithsonian magazine writer Andy Kifer discusses the complexities of Oppenheimer's genius and how prior attempts to depict him in film and television and on stage have fared. Read Andy Kifer’s “The Real Story Behind Christopher Nolan’s Oppenheimer” here (https://www.smithsonianmag.com/history/the-real-history-behind-christopher-nolans-oppenheimer-180982529/) . See Minesh Bacrania’s photographs of Los Alamos and read Smithsonian senior editor Jennie Rothenberg Gritz’s text here (https://www.smithsonianmag.com/history/exclusive-behind-scenes-look-los-alamos-lab-where-robert-oppenheimer-created-atomic-bomb-180982336/) or in the July/August 2023 issue of Smithsonian. Original release date: July 27, 2023 There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Genevieve Sponsler, Adriana Rozas Rivera, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Episode artwork by Emily Lankiewicz. Music by APM Music. Full Article
ux Canadian mixed doubles curlers in flux, air thoughts on Olympic selection process By www.cbc.ca Published On :: Thu, 06 Jan 2022 00:10:58 EST The cancellation of the mixed doubles curling trials has generated a wide variety of emotions among players — illuminating a handful of issues, particularly about scheduling and the selection process as a whole. Full Article Sports/Olympics/Winter Sports/Curling
ux Aqualux drains wasted time out of shower design with SolidWorks and 3DVIA By www.solidworks.com Published On :: Mon, 06 Oct 2008 00:00:00 -0500 Quick design turnaround and easy documentation process help UK-based company move products to market faster Full Article
ux Cosmic Blobs unveils 'Deluxe' Edition plus new collection of expansion packs By www.solidworks.com Published On :: Tue, 19 Sep 2006 00:00:00 -0500 New offerings present even more possibilities for powerful and fun 3D graphics software for kids Full Article
ux Elevate your collection with Apple Music's luxurious 100 best albums book By appleinsider.com Published On :: Mon, 11 Nov 2024 22:01:58 +0000 Apple Musicis turning its "100 Best Albums" list into a luxurious collectible book, bringing iconic records from the screen to your shelf.Apple Music: 100 Best Albums. Image credit: AssoulineEarlier in 2024, Apple launched its "100 Best Albums" list directly in the Apple Music app, sparking plenty of lively debates among fans. Now, the company is releasing the list in a different medium.The Apple Music: 100 Best Albums book is a heavyweight in more ways than one. It weighs 8 pounds and has luxurious touches like a linen cover, gold page edges, and an acrylic slipcase. Each copy is hand-numbered, making it a unique piece of music history. Continue Reading on AppleInsider | Discuss on our Forums Full Article
ux News24 Business | Malatsi confirms plans to scrap smartphone luxury tax, address SABC Bill controversy By www.news24.com Published On :: Wednesday Nov 13 2024 05:00:53 Minister of Communications and Digital Technologies Solly Malatsi has said his department will look into scrapping luxury tax on smartphones. Full Article
ux News24 Business | TAKE A LOOK | SA's biggest landlord to turn Bedfordview office park into luxury apartments By www.news24.com Published On :: Monday Feb 07 2022 11:26:06 Growthpoint Properties will spend R200 million to convert its 35 000 square metre Riverwoods office park into a resort with luxury apartments. Full Article
ux A Luxurious Evening At D'MONDE Members Club: The Perfect Place To Enjoy Indulgence With Elegance By food.ndtv.com Published On :: Tue, 05 Nov 2024 21:07:00 +0530 D'MONDE is an exclusive members-only club that offers opulence through its various offerings. Full Article
ux To Eat Or Not To Eat? 11 Best And Worst Foods For Acid Reflux By food.ndtv.com Published On :: Thu, 07 Nov 2024 15:17:14 +0530 Acidity? We got some expert tips to tackle acid reflux with a good diet and eating habits. Dietitian shared some dos and don'ts to follow in your diet. Full Article
ux Asus Zenbook 14X OLED (Space Edition) UX5401ZAS 12th Gen core i9-12900H (2022) Review By www.digit.in Published On :: 2023-09-22T13:09:00+05:30 Read the in depth Review of Asus Zenbook 14X OLED (Space Edition) UX5401ZAS 12th Gen core i9-12900H (2022) Laptops. Know detailed info about Asus Zenbook 14X OLED (Space Edition) UX5401ZAS 12th Gen core i9-12900H (2022) configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback. Full Article Laptops
ux How To Excel At Great UX Design By www.digit.in Published On :: 2014-12-30T16:53:00+05:30 NA Full Article How To
ux USB crash issue in Linux 4.14.62 By community.cadence.com Published On :: Tue, 16 Apr 2019 07:16:31 GMT Hi , FIrst of all , I hope I have posted my query in the right place . I am expecting software support/suggestions for the below issue. I am working on LTE which use USB interface and the Host Controller is USB 2.0 . The BSP is from NXP which supports Cadence USB 3.0 Host controller and with USB 3.0 supported cadence driver.NXP had used the USB 3.0 host controller for USB type C based device. Cadence USB 3.0 based device driver seems to be backward compatible for USB 2.0 host controller .Since basic LTE functionalities seems to be working fine I continued to use the same driver in Linux 4.14.62 But I am facing a kernel warning of unhandled interrupt and the crash log points to cdns_irq function as shown below The crash/kerenel warning is very random and not occuring all the time. .691533] irq 36: nobody cared (try booting with the "irqpoll" option) [ 1.698242] CPU: 0 PID: 87 Comm: kworker/0:1 Not tainted 4.9.88 #24 [ 1.704509] Hardware name: Freescale i.MX8QXP MEK (DT) [ 1.709659] Workqueue: pm pm_runtime_work [ 1.713675] Call trace: [ 1.716123] [<ffff0000080897d0>] dump_backtrace+0x0/0x1b0 [ 1.721523] [<ffff000008089994>] show_stack+0x14/0x20 [ 1.726582] [<ffff0000083daff0>] dump_stack+0x94/0xb4 [ 1.731638] [<ffff00000810f064>] __report_bad_irq+0x34/0xf0 [ 1.737212] [<ffff00000810f4ec>] note_interrupt+0x2e4/0x330 [ 1.742790] [<ffff00000810c594>] handle_irq_event_percpu+0x44/0x58 [ 1.748974] [<ffff00000810c5f0>] handle_irq_event+0x48/0x78 [ 1.754553] [<ffff0000081100a8>] handle_fasteoi_irq+0xc0/0x1b0 [ 1.760390] [<ffff00000810b584>] generic_handle_irq+0x24/0x38 [ 1.766141] [<ffff00000810bbe4>] __handle_domain_irq+0x5c/0xb8 [ 1.771979] [<ffff000008081798>] gic_handle_irq+0x70/0x15c 1.807416] 7a40: 00000000000002ba ffff80002645bf00 00000000fa83b2da 0000000001fe116e [ 1.815252] 7a60: ffff000088bf7c47 ffffffffffffffff 00000000000003f8 ffff0000085c47b8 [ 1.823088] 7a80: 0000000000000010 ffff800026484600 0000000000000001 ffff8000266e9718 [ 1.830925] 7aa0: ffff00000b8b0008 ffff800026784280 ffff00000b8b000c ffff00000b8d8018 [ 1.838760] 7ac0: 0000000000000001 ffff000008b76000 0000000000000000 ffff800026497b20 [ 1.846596] 7ae0: ffff00000810bd24 ffff800026497b20 ffff000008851d18 0000000000000145 [ 1.854433] 7b00: ffff000008b8d6c0 ffff0000081102d8 ffffffffffffffff ffff00000810dda8 [ 1.862268] [<ffff000008082eec>] el1_irq+0xac/0x120 [ 1.867155] [<ffff000008851d18>] _raw_spin_unlock_irqrestore+0x18/0x48 [ 1.873684] [<ffff00000810bd24>] __irq_put_desc_unlock+0x1c/0x48 [ 1.879695] [<ffff00000810de10>] enable_irq+0x48/0x70 [ 1.884756] [<ffff0000085ba8f8>] cdns3_enter_suspend+0x1f0/0x440 [ 1.890764] [<ffff0000085baca0>] cdns3_runtime_suspend+0x48/0x88 [ 1.896776] [<ffff0000084cf398>] pm_generic_runtime_suspend+0x28/0x40 [ 1.903223] [<ffff0000084dc3e8>] genpd_runtime_suspend+0x88/0x1d8 [ 1.909320] [<ffff0000084d0e08>] __rpm_callback+0x70/0x98 [ 1.914724] [<ffff0000084d0e50>] rpm_callback+0x20/0x88 [ 1.919954] [<ffff0000084d1b2c>] rpm_suspend+0xf4/0x4c8 [ 1.925184] [<ffff0000084d20fc>] rpm_idle+0x124/0x168 [ 1.930240] [<ffff0000084d26c0>] pm_runtime_work+0xa0/0xb8 [ 1.935732] [<ffff0000080dc1dc>] process_one_work+0x1dc/0x380 [ 1.941481] [<ffff0000080dc3c8>] worker_thread+0x48/0x4d0 [ 1.946885] [<ffff0000080e2408>] kthread+0xf8/0x100[ 1.957080] handlers: [ 1.959350] [<ffff0000085ba668>] cdns3_irq [ 1.963449] Disabling IRQ #36 Kindly provide a solution to solve this issue. Thanks & Regards, Anjali Full Article
ux Setup SSH authentication with PEM RSA file without password on ubuntu/linux Raspberry Pi Server By www.9lessons.info Published On :: Mon, 26 Apr 2021 22:45:00 -0400 Recently I have been working with Raspberry PI and creating my own home server to host some of my demo projects. This post is about setting up SSH authentication with a PEM certificate file without password on ubuntu/linux server. Implement the following steps and improve the security. Full Article linux pem raspberrypi ubuntu vpn
ux Hydroflux finds sustainable success in the Pacific By www.austrade.gov.au Published On :: Sun, 27 Aug 2023 22:42:00 GMT Australian environmental services company Hydroflux is providing sustainable water solutions and services to Pacific nations. Full Article Success stories
ux Auxin Solar alleges unfair trade practices from Chinese suppliers, asks Commerce to intervene By www.renewableenergyworld.com Published On :: Thu, 10 Feb 2022 15:27:28 +0000 Auxin Solar named more than a dozen companies in its petition to Commerce Department officials. Full Article News Solar Utility Scale anti-dumping Auxin Solar Chinese imports Solar Energy Industries Association
ux Austin Calling: As Texas Absorbs Influx of Residents, Rekor Taps NVIDIA Technology for Roadway Safety, Traffic Relief By blogs.nvidia.com Published On :: Tue, 05 Nov 2024 16:00:43 +0000 Austin is drawing people to jobs, music venues, comedy clubs, barbecue and more. But with this boom has come a big city blues: traffic jams. Rekor, which offers traffic management and public safety analytics, has a front-row seat to the increasing traffic from an influx of new residents migrating to Austin. Rekor works with the Read Article Full Article Accelerated Analytics Metropolis Social Impact
ux Guddiga Doorashooyinka Jubaland oo doortay Guddoomiye iyo Kuxigeen By horseedmedia.net Published On :: Mon, 11 Nov 2024 17:19:48 +0000 Guddiga Doorashooyinka iyo xuduudaha dowlad goboleedka Jubaland ayaa doortay Guddoomiye, Guddoomiye kuxigeen iyo xoghaye. Guddiga doorashada… The post Guddiga Doorashooyinka Jubaland oo doortay Guddoomiye iyo Kuxigeen appeared first on Horseed Media. Full Article Jubaland News
ux Liam Payne's luxury manor up for rental availability for astonishing sum By www.thenews.com.pk Published On :: Tue, 12 Nov 2024 19:32:00 +0500 Liam Payne moved in to his new house with GF Kate Cassidy in SeptemberLate singer, Liam Payne’s luxury mansion has been put on rent within a month of the Teardrops singer’s passing. Payne shifted to his new manor with girlfriend, Kate Cassidy located in the South Florida in... Full Article
ux Gastric Band Weight-Loss Surgery Can Boost Reflux By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Gastric Band Weight-Loss Surgery Can Boost RefluxCategory: Health NewsCreated: 8/23/2008 2:00:00 AMLast Editorial Review: 8/25/2008 12:00:00 AM Full Article
ux GERD (Acid Reflux) in Infants and Children By www.medicinenet.com Published On :: Thu, 18 Aug 2022 00:00:00 PDT Title: GERD (Acid Reflux) in Infants and ChildrenCategory: Diseases and ConditionsCreated: 1/31/2005 12:00:00 AMLast Editorial Review: 8/18/2022 12:00:00 AM Full Article
ux The antivirulent Staphylococcal sRNA SprC regulates CzrB efflux pump to adapt its response to zinc toxicity [ARTICLE] By rnajournal.cshlp.org Published On :: 2024-10-16T07:18:13-07:00 Bacterial regulatory RNAs (sRNAs) are important players to control gene expression. In Staphylococcus aureus, SprC is an antivirulent trans-acting sRNA known to base-pair with the major autolysin atl mRNA, preventing its translation. Using MS2-affinity purification coupled with RNA sequencing, we looked for its sRNA-RNA interactome and identified 14 novel mRNA targets. In vitro biochemical investigations revealed that SprC binds two of them, czrB and deoD, and uses a single accessible region to regulate its targets, including Atl translation. Unlike Atl regulation, the characterization of the SprC-czrB interaction pinpointed a destabilization of the czrAB cotranscript, leading to a decrease of the mRNA level that impaired CzrB zinc efflux pump expression. On a physiological standpoint, we showed that SprC expression is detrimental to combat against zinc toxicity. In addition, phagocyctosis assays revealed a significant, but moderate, increase of czrB mRNA levels in a sprC-deleted mutant, indicating a functional link between SprC and czrB upon internalization in macrophages, and suggesting a role in resistance to both oxidative and zinc bursts. Altogether, our data uncover a novel pathway in which SprC is implicated, highlighting the multiple strategies used by S. aureus to balance virulence using an RNA regulator. Full Article
ux Des politiques pour mieux soutenir les chirurgiennes enceintes [Commentaire] By www.cmaj.ca Published On :: 2024-11-11T21:05:15-08:00 Full Article
ux Far-right groups gain ground in Sweden and Germany amid migrant influx By www.pbs.org Published On :: Tue, 17 Oct 2017 22:30:37 +0000 Watch Video | Listen to the AudioJUDY WOODRUFF: But first: Sunday’s elections Austria were the latest ample of a shift to the right Europe’s politics, as 31-year-old Christian Kurz was elected chancellor on an anti-immigration platform. He may now form a government with a far-right party founded in the 1950s by former Nazis. That follows recent elections in Germany, where a far-right party roiled the race and dealt a blow to returning leader Angela Merkel. In Sweden, too, there is a strong challenge from the right and a neo-Nazi group that looks stand in elections next year. Special correspondent Malcolm Brabant ha been surveying the political landscape in Germany and Sweden, and he begins his report in Scandinavia. MALCOLM BRABANT, Special Correspondent: In a Gothenburg parking lot, supporters of the Nordic Resistance Movement form up for what they hope will be their biggest-ever march, to propagate an ideology espoused by mother of eight Paulina Forslund. PAULINA FORSLUND, Nordic Resistance Movement: When white becomes the minority, they will be destroyed. I want my children to have a secure future. I want them not only for them to have a secure Sweden. I want them to have a secure world. And I want other people to fight for the same thing. MALCOLM BRABANT: When addressing her fellow neo-Nazis, Forslund’s rhetoric sharpens. PAULINA FORSLUND (through interpreter): I’m the welder’s daughter, the forester’s grandchild. My line consists of hardworking men and women. It’s people like them we can thank for the welfare system that our lying politicians are now giving away to imported scum. MALCOLM BRABANT: Clearly expecting trouble, the movement’s leaders have a muscular protection detail, marching past a silent protest. The sign reads “No Nazis on our streets.” This protester would only give her name as Johanna. JOHANNA, Anti-Nazi Protester: They are racist people. They are people who think that certain people are better than others, and I will not stand for that. It’s not something I think has a place in a modern society. MALCOLM BRABANT: Experts say the resistance movement is recruiting aggressively, and believe this demonstration is emblematic of the rise of the far right. It took place on Yom Kippur, the Jewish day of atonement. Allan Stutzinky is leader of Gothenburg’s Jewish community. ALLAN STUTZINKY, Jewish Community Leader (through interpreter): Nazism has returned. The descendants of the murderers are organizing the same marches today, waving the same flags, shouting the same slogans, and have the same racist agenda. MALCOLM BRABANT: Anna Johansson is a member of the governing Social Democrat Party. It’s considering outlawing the Nordic Resistance Movement. ANNA JOHANSSON, Swedish Social Democratic Party: In Sweden and in Denmark, and in other countries, extreme parties are growing, and the hatred is spreading around. MALCOLM BRABANT: “Go home to mama,” he shouts. “Nazi pigs,” chant the anti- fascist protesters, as a bottle flies through the air. DAMON, Nordic Resistance Movement: If someone calls themselves a Nazi, most of us would dissociate with that person. That’s nothing we stand for ourselves. I never call myself a Nazi. I’m a national socialist. MALCOLM BRABANT: Hitler’s party was also called National Socialist, but Damon, a 40-year-old welder, insists he’s a nonviolent family man. DAMON: The demographic landscape of our — of the whole of Europe is changing, so, basically, it’s a concern on preserving my heritage for my family and our kin. MALCOLM BRABANT: This demonstration has been stopped short of its destination. The Nordic Resistance Movement is currently trapped between a line of police and anti-fascist protesters. And it looks as though this demonstration isn’t going any further. Violence briefly erupts as the resistance movement tries to break through police lines, and several marchers are arrested. PAULINA FORSLUND: We are not your enemy. We are the government’s enemy. They say we live in a democracy, but we have never had an election about if we want to take all these people in. MALCOLM BRABANT: When Europe’s refugee crisis began in 2015, Sweden copied Germany’s open-door policy, and 160,000 migrants entered the country. Two years on, Sweden has tighter borders and has begun deporting some of the newcomers. The new atmosphere alarms Floid Gumbo, entertaining an anti-Nazi rally. FLOID GUMBO, Singer Originally from Zimbabwe: I came to Sweden over 20 years ago. The climate in Sweden, the people were so friendly, and things were completely different, more welcoming. And I feel like things have sort of gradually changed. I’m very concerned, because I have children, because I’m thinking what I experienced here is not the same kind of climate, atmosphere that they are going to experience here. ANNA JOHANSSON: It’s not so long ago that the Nazis ruined Europe. And that makes me very worried. The German elections were terrifying, I think. MALCOLM BRABANT: Johansson is referring to last month’s success of the right-wing Alternative For Germany Party, or AFD, when it entered Parliament for the first time with 13 percent of the vote. HUGH BRONSON, Alternative For Germany Party: The AFD only came into existence because Merkel deserted the traditional conservative Christian voters. They were looking for a home, and the AFD has offered them a safe place. MALCOLM BRABANT: Hugh Bronson is deputy leader of the AFD in Berlin. Now his party, the third largest in Parliament, is demanding that Angela Merkel imposes tougher immigration rules. Your opponents claim that you are a party of hate. What’s your response to that? HUGH BRONSON: We embrace foreigners who respect our laws, pay their taxes, send their children to school, and go about their normal life. The problem is with people who abuse the system to have a better life, or let others pay for their better lives, or who are criminals. MALCOLM BRABANT: Outside the opera house in Dresden, former East Germany, singer Luca Bergelt is dismayed by the political landscape shifting to the right. LUCA BERGELT, Singer: My fear is that they will tear Europe apart. They are going to raise up the walls again. They’re going to build new walls between the countries, and that Europe will get more close into itself. MALCOLM BRABANT: Anti-immigrant sentiment is strong in Dresden. The city was the birthplace of a pan-European anti-Islamic movement, and it delivered the largest number of votes for the right-wing party. On a holiday to celebrate German unification after the fall of communism, retired engineer Wilfried Schmidt explained why he sent a message to Angela Merkel. WILFRIED SCHMIDT, Retired Engineer (through interpretor): Let’s put it this way. We all need to recognize that Germany is undergoing social changes that are becoming harder to control. For one, there is mass immigration from difficult regions that is increasingly uncontrollable, of people with entirely different concepts of life, from fundamental differently structured societies that are problematic. MALCOLM BRABANT: About one million migrants poured into Germany in 2015. Chancellor Merkel consistently defended her pro-refugee policies, but now she has been punished by voters who believe she ignored their concerns. Chancellor Merkel has promised to listen to the people who voted for the AFD, and she says she’s going to try to win them over with what she calls good politics. But she will not countenance having the party in her coalition. But the chancellor needs to find new partners who are prepared to be tough on immigration. As she tries to forge a coalition, the chancellor has agreed to put an annual cap of 200,000 on the number of immigrants, something she previously refused to do. But will it be enough to woo back people who deserted her at the election? A question for Werner Patzelt, a political scientist at Dresden University. WERNER PATZELT, Dresden University: Since Chancellor Merkel has made so many U-turns in German domestic politics, it wouldn’t be a surprise if she would try to do a U-turn, also winning back AFD voters. But this is a really hard political task, because so many of them are so much disappointed by the Christian Democratic Union in general, and by Chancellor Merkel in particular, that they will do anything to avoid going back. MALCOLM BRABANT: Back in Sweden, the governing party is horrified at the concept of conceding ground to right-wingers, and is trying to isolate them. ANNA JOHANSSON: Experience shows that, when you adopt the ideas from these right-wing parties, they spread. These parties have their agenda implemented by other parties. And I wouldn’t want to see that happen in Sweden. FLOID GUMBO: We’re all human beings. We share this world. We’re all here. There’s enough space for us all. MALCOLM BRABANT: But that’s an appeal that an increasing number of Swedes are rejecting, as the country and much of Europe go through a crisis of identity. For the PBS NewsHour, I’m Malcolm Brabant in Gothenburg. The post Far-right groups gain ground in Sweden and Germany amid migrant influx appeared first on PBS NewsHour. Full Article Austria elections europe Far-Right Politics
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