With bad economy and tough lifestyles- we folks have all the more reason to pay God a visit. But people no longer take the pains to dress up for the occasion. Going to church is an itinerary that is squeezed into our hectic schedules. We...

Lewis Library - ML410.B8 S42 2018

The time has come for India to adopt a “whole-of-government approach” in decisively confronting the “strategic uncertainties” looming on its horizon a

1. Astronomers Identify Closest Black Hole to Earth  VOA Learning English
2. Astronomers find closest black hole to Earth yet to be discovered  9News
3. New black hole discovered - and it's the closest to Earth ever found, say scientists  Mirror Online
4. View Full coverage on Google News

Dark, handsome bearded and tattooed, Latin Lucca Santanna can’t get enough of brown Brazilian top Cesar Dotadao. Starting at his nips and chest Lucca works down till he’s faced with cramming Cesar’s big fat 9-incher down his throat. He gags a little but gets it good and wet. See more at RawHole.

The post RawHole: Lucca Santanna and Cesar Dotadao appeared first on QueerClick.

Princeton University researchers have discovered that the bacteria behind the life-threatening disease cholera initiates infection by coordinating a wave of mass shapeshifting that allows them to more effectively penetrate their victims' intestines. The researchers also identified the protein that allows Vibrio cholerae to morph, and found that it's activated through quorum sensing. The findings could lead to new treatments for cholera that target the bacteria's ability to change shape or penetrate the gut.

At first, it was hard to hear what Turk Wendell was saying from atop his tractor.

At first, it was hard to hear what Turk Wendell was saying from atop his tractor.

At first, it was hard to hear what Turk Wendell was saying from atop his tractor.

β-Glucocerebrosidase (GBA) hydrolyzes glucosylceramide (GlcCer) to generate ceramide. Previously, we demonstrated that lysosomal GBA1 and nonlysosomal GBA2 possess not only GlcCer hydrolase activity, but also transglucosylation activity to transfer the glucose residue from GlcCer to cholesterol to form β-cholesterylglucoside (β-GlcChol) in vitro. β-GlcChol is a member of sterylglycosides present in diverse species. How GBA1 and GBA2 mediate β-GlcChol metabolism in the brain is unknown. Here, we purified and characterized sterylglycosides from rodent and fish brains. Although glucose is thought to be the sole carbohydrate component of sterylglycosides in vertebrates, structural analysis of rat brain sterylglycosides revealed the presence of galactosylated cholesterol (β-GalChol), in addition to β-GlcChol. Analyses of brain tissues from GBA2-deficient mice and GBA1- and/or GBA2-deficient Japanese rice fish (Oryzias latipes) revealed that GBA1 and GBA2 are responsible for β-GlcChol degradation and formation, respectively, and that both GBA1 and GBA2 are responsible for β-GalChol formation. Liquid chromatography–tandem MS revealed that β-GlcChol and β-GalChol are present throughout development from embryo to adult in the mouse brain. We found that β-GalChol expression depends on galactosylceramide (GalCer), and developmental onset of β-GalChol biosynthesis appeared to be during myelination. We also found that β-GlcChol and β-GalChol are secreted from neurons and glial cells in association with exosomes. In vitro enzyme assays confirmed that GBA1 and GBA2 have transgalactosylation activity to transfer the galactose residue from GalCer to cholesterol to form β-GalChol. This is the first report of the existence of β-GalChol in vertebrates and how β-GlcChol and β-GalChol are formed in the brain.

A team of artists from the OM Arts School of Mission reach out locally to people with special needs in Val Pellice, Italy.

Bus4Life ministers in Central and Eastern Europe, bringing hope and Christian literature to the region's widespread towns and villages. During the spring and early summer of 2018, Bus4Life visited Hungary, Moldova, and Ukraine.

There are dozens of ways to access networks and today, remote offices are common.

The geothermal heat pump (GHP) industry prides itself on offering an efficient, environmentally friendly technology for satisfying the thermal loads of buildings. To do so, a GHP system relies on circulating water through pipes placed underground (either vertically or horizontally) to tap the natural heat retained by the earth.

European astronomers have found the closest black hole to Earth yet, so near that the two stars dancing with it can be seen by the naked eye.

The Cornhole Mania 2020 doubles tournament broadcasted on ESPN noon, and the singles event will take place at 6 p.m. as some live sports begin making a comeback.

Beyoncé’s whole family, including her mother, Tina Knowles-Lawson, and sister, Solange Knowles, have tested negative for the coronavirus, meaning they may be able to spend Mother’s Day together as usual. On Friday, Mama Tina sat down for a virtual chat with Tamron Hall. During the interview, she revealed that her whole family, including Beyoncé and Jay-Z […]

The post Beyoncé And Jay Z Had The Whole Family Tested For Coronavirus appeared first on Chart Attack.

Brunch, sorted

A loose manhole cover was responsible for causing Rubens Barrichello's spectacular accident in the Monaco Grand Prix

India is a land of traditions, fun, fairs and festivals. Despite all the madness, poverty, hunger, corruption and viole

Climate change and, more generally, environmental damage have quantifiable economic and health costs, which weigh on long-term growth and well-being. If left unchecked, climate change is projected to decrease global GDP by 0.7 to 2.5 % by 2060. At the same time, the costs to society of air pollution already appear substantial–equivalent to some 4% of GDP across OECD countries and even higher in some rapidly developing economies.

Climate change and, more generally, environmental damage have quantifiable economic and health costs, which weigh on long-term growth and well-being. If left unchecked, climate change is projected to decrease global GDP by 0.7 to 2.5 % by 2060. At the same time, the costs to society of air pollution already appear substantial–equivalent to some 4% of GDP across OECD countries and even higher in some rapidly developing economies.

Climate change and, more generally, environmental damage have quantifiable economic and health costs, which weigh on long-term growth and well-being. If left unchecked, climate change is projected to decrease global GDP by 0.7 to 2.5 % by 2060. At the same time, the costs to society of air pollution already appear substantial–equivalent to some 4% of GDP across OECD countries and even higher in some rapidly developing economies.

Brazil must build on the positive momentum started with its new Corporate Liability Law and its first indictments in one foreign bribery case to investigate and prosecute more proactively foreign bribery.

Colombia needs to improve its capacity to investigate foreign bribery by establishing an effective corporate liability regime, improving coordination between its numerous agencies and more rigorously training law enforcement, according to a new report by the OECD Working Group on Bribery.

Countries must step up work to ensure that tax authorities and anti-corruption authorities can effectively co-operate in the fight against tax evasion, bribery, and other forms of corruption, according to a joint OECD/World Bank report.

Road users can rapidly find themselves out of pocket if their bike or vehicle is damaged by one, while cyclists can easily be injured if a pothole causes them to come off their bike.

Lawyer Nick Freeman (left) believes that many motorists are lulled into a false sense of security during the Covid-19 restrictions and has produced a list of things drivers need to know.

Archives, Room Use Only - HE8110.C33 B34 1978