Extracellular vesicles (EVs) secreted by the epididymal epithelium transfer to spermatozoa key proteins that are essential in promoting motility and subsequent fertilization success. Using the domestic cat model, the objectives were to (1) characterize and compare protein content of EVs between segments of the epididymis, and (2) compare EV protein compositions between normo- and teratospermic individuals (producing >60% of abnormal spermatozoa). Epididymal EVs from adult cats were isolated and assessed via liquid chromatography tandem MS. Both male types shared 3008 proteins in total, with 98 and 20 EV proteins unique to normospermic and teratospermic males, respectively. Expression levels of several proteins changed between epididymal segments in both male types. Several proteins in both groups were related to sperm motility (e.g. hexokinase 1, adenylate kinase isoenzyme) and zona pellucida or oolemma binding (e.g. disintegrin and metalloproteinase domain proteins, zona binding proteins 1 and 2). Interestingly, seven cauda-derived EV proteins trended downward in teratospermic compared with normospermic males, which may relate to poor sperm quality. Collective results revealed, for the first time, EV proteins related to sequential sperm maturation with differences observed between normospermic and teratospermic individuals.

Exploring Public International Law and the Rights of Individuals with Chinese Scholars - Part One Other resource sysadmin 29 October 2018

As part of a roundtable series, Chatham House and China University of Political Science and Law (CUPL) jointly organized this four-day meeting at Chatham House for international lawyers to discuss a wide range of issues related to public international law and the rights of individuals.

The specific objectives were to:

• create a platform for Chinese international law academics working on international human rights law issues to present their thinking and exchange ideas with counterparts from outside China;
• build stronger understanding within the wider international law community of intellectual debates taking place in China about the international human rights system and China’s role within it;
• support networking between Chinese and non-Chinese academics working on international human rights and related areas of international law.

The roundtable forms part of a wider Chatham House project exploring China’s impact on the international human rights system and was inspired by early discussions with a burgeoning community of Chinese academics thinking, writing (mainly in Chinese) and teaching about international human rights law.

For China University of Political Science and Law, one of the largest and most prestigious law schools in China and perhaps the only university in the world with an entire faculty of international law, the initiative is part of a drive to forge partnerships beyond China in the international law field.

The roundtable had a total of 22 participants, 10 Chinese (from universities and other academic institutions in Beijing and Shanghai) and 12 non-Chinese (from Australia, Germany, the Netherlands, Switzerland, the United Kingdom and the United States).

All discussions were held in English under the Chatham House Rule.

Exploring Public International Law and the Rights of Individuals with Chinese Scholars - Part Two Other resource sysadmin 30 October 2018

As part of a roundtable series, Chatham House and China University of Political Science and Law (CUPL) held a two-day roundtable meeting in Beijing on public international law and the rights of individuals.

The specific objectives were to:

• create a platform for Chinese international law academics working on international human rights law issues to present their thinking and exchange ideas with counterparts from outside China;
• build stronger understanding within the wider international law community of intellectual debates taking place in China about the international human rights system and China’s role within it;
• support networking between Chinese and non-Chinese academics working on international human rights and related areas of international law.

The roundtable forms part of a wider Chatham House project exploring China’s impact on the international human rights system and was inspired by early discussions with a burgeoning community of Chinese academics thinking, writing (mainly in Chinese) and teaching about international human rights law.

For CUPL, one of the largest and most prestigious law schools in China and perhaps the only university in the world with an entire faculty of international law, the initiative is part of a drive to forge partnerships beyond China in the international law field.

The meeting in Beijing was hosted by CUPL and involved 20 participants, 10 Chinese (from universities and other academic institutions in Beijing) and 10 non-Chinese (from Australia, the Netherlands, South Africa, Switzerland, the United Kingdom and the United States).

To ensure continuity while also expanding the experts network being built, the second meeting included a mix of participants from the first meeting and some new participants.

All discussions were held in English under the Chatham House Rule.

Exploring Public International Law and the Rights of Individuals with Chinese Scholars - Part Three Other resource sysadmin 30 October 2018

As part of a roundtable series, Chatham House, China University of Political Science and Law (CUPL) and the Graduate Institute Geneva held a two-day roundtable meeting in Geneva on public international law and the rights of individuals.

The specific objectives were to:

• create a platform for Chinese international law academics working on international human rights law issues to present their thinking and exchange ideas with counterparts from outside China;
• build stronger understanding within the wider international law community of intellectual debates taking place in China about the international human rights system and China’s role within it;
• support networking between Chinese and non-Chinese academics working on international human rights and related areas of international law.

The roundtable forms part of a wider Chatham House project exploring China’s impact on the international human rights system and was inspired by early discussions with a burgeoning community of Chinese academics thinking, writing (mainly in Chinese) and teaching about international human rights law.

For CUPL, one of the largest and most prestigious law schools in China and perhaps the only university in the world with an entire faculty of international law, the initiative is part of a drive to forge partnerships beyond China in the international law field.

The meeting in Geneva was co-hosted by the Graduate Institute Geneva and involved 19 participants, 9 Chinese (from six research institutions in Beijing and Shanghai) and 11 non-Chinese (from eight research institutions in Australia, Germany, the Netherlands, Switzerland, the United Kingdom and the United States).

To ensure continuity while also expanding the expert network being built, the third meeting included a mix of participants from the first two meetings and some new participants

All discussions were held in English under the Chatham House Rule.

The first step to saving nature is the rewilding of our own minds, says conservationist and former Patagonia CEO Kristine McDivitt Tompkins. With an unwavering commitment to protecting ecosystems, she and her late husband Douglas Tompkins created vast conservation parks across South America that allowed ancient flora and fauna to flourish once again. Now, she's carrying that legacy and mission forward with a bold plan to connect parks across geographic boundaries, creating a system of continental-scale wildlife corridors — before it's too late.

Florida's governor signed a bill that will allow schools to arm classroom teachers, part of a longer list of school safety changes made after a school shooting in Parkland, Fla., last year.

Nearly 17 million children lack high-speed internet at home that's considered crucial to their ability to participate in remote learning during the pandemic, according to a new study.

Different people listening to the same story may converge upon a largely shared interpretation while still developing idiosyncratic experiences atop that shared foundation. What linguistic properties support this individualized experience of natural language? Here, we investigate how the "concrete–abstract" axis—the extent to which a word is grounded in sensory experience—relates to within- and across-subject variability in the neural representations of language. Leveraging a dataset of human participants of both sexes who each listened to four auditory stories while undergoing functional magnetic resonance imaging, we demonstrate that neural representations of "concreteness" are both reliable across stories and relatively unique to individuals, while neural representations of "abstractness" are variable both within individuals and across the population. Using natural language processing tools, we show that concrete words exhibit similar neural representations despite spanning larger distances within a high-dimensional semantic space, which potentially reflects an underlying representational signature of sensory experience—namely, imageability—shared by concrete words but absent from abstract words. Our findings situate the concrete–abstract axis as a core dimension that supports both shared and individualized representations of natural language.

The vertical sign stretched across three stories of the Manhattan hotel, which once welcomed the likes of Bob Dylan, Patti Smith, Andy Warhol and Janis Joplin

Texts like the "Sortes Astrampsychi" promised insights on clients' love lives, career prospects, financial woes and families

Interim PC Leader Glen Savoie urged members to find a common purpose rather than blame former leader Blaine Higgs.

CME Group, the world's leading derivatives marketplace, today declared a fourth-quarter dividend of $1.15 per share. The dividend is payable December 27, 2024, to shareholders of record as of...

SolidWorks 3D mechanical design and COSMOS design analysis software play key roles in developing regulator that reached more than 1,000 feet deep

Leading assembly automation and testing company to standardize on SolidWorks Office Professional, securely manage design data with PDMWorks

Hospitality stakeholders and organizations can serve a significant role in the integration of people who have criminal records or histories of incarceration back into the workforce, according to a new framework created by researchers in the Penn State School of Hospitality Management.

Visiting an elderly home, a ‘Love Moldova’ outreach team experiences how God touches lives and has arranged even the staff’s working hours.

An underprivileged young man succeeds in building a future as God brings encounters with the right people at the right moments.

God turns a frustrating situation into one of hope when a lost OM team meets a girl who asks for prayer.

A News24 reader looks to an expert for guidance on the best investment vehicles for each of her children.

A former computer engineer turned motivational speaker will share his dynamic insights on “Bridging the Digital Divide: Unlocking Access and Opportunity in Education” during a Nov. 6 presentation of the Technology & Society Colloquia Series at Pennsylvania College of Technology.

Active-duty service members and veterans experiencing PTSD have additional opportunities for treatment to support them, along with their partners, after the Department of Defense awarded a $3 million grant to Steffany Fredman, associate professor of human development and family studies, and colleagues in the STRONG STAR Consortium.

Artespaço, OM Brazil’s art ministry, connects Christian artists to opportunities to serve in their communities and abroad.

New findings reveal that mitochondria in nutrient-deprived cells adopt specialised roles to prioritise either energy generation or amino acid synthesis. Led by Dr. Craig Thompson of Memorial Sloan Kettering Cancer Center, the study identified specific mitochondrial subpopulations, allowing cells to maintain critical functions even under stress. These discoveries have implications for understanding how cancer cells survive low-nutrient conditions and how cells repair after injury.

An Argentinian club drew the ire of the country's football community after selecting an influencer with no professional experience in its starting XI for a top-flight match

Thousands of Highmark 2019 plan participants and groups to receive checks After announcing a reduction of Delaware Health Insurance Marketplace rates for the upcoming enrollment year, Insurance Commissioner Trinidad Navarro has more good news for residents who purchase insurance on the Delaware Health Insurance Marketplace, those who purchase Highmark Blue Cross Blue Shield Delaware plans […]

Highmark plan participants and groups to receive checks Insurance Commissioner Trinidad Navarro announced today that Highmark Blue Cross Blue Shield Delaware will issue rebates totaling over $12.3 million to some Delawareans. Residents who purchase insurance on the Delaware Health Insurance Marketplace, those who purchase Highmark Delaware plans outside of the marketplace, and Highmark small group […]

Increased competition means more options for Delawareans, employers For the second consecutive year, Delawareans will have access to increased options on the Health Insurance Marketplace, Insurance Commissioner Trinidad Navarro announced today, with 57 total plans offered by four insurers. In the 2024 plan year, consumers will have the opportunity to purchase plans from Celtic Insurance […]

Twenty-five Delaware artists to receive recognition Wilmington, Del. (January 11, 2021) – Twenty-five Delaware artists are being recognized by the Delaware Division of the Arts for the high quality of their artwork. Work samples from 121 Delaware choreographers, composers, musicians, writers, folk and visual artists were reviewed by out-of-state arts professionals, considering demonstrated creativity and […]

Five virtual programs to be streamed live on the Web for African American History Month.

Virtual programs celebrate women's lives and historic achievements.

DDOA Invites Public Comment on Its FY2022–FY2025 Strategic Plan Wilmington, Del. (March 5, 2021) – The Delaware Division of the Arts (DDOA) invites public comment through March 14, 2021 on the final draft of its new four-year strategic plan. Public feedback is critical in finalizing the plan on behalf of constituents across the state. The […]

DOVER, Del.— Delaware Secretary of State Jeff Bullock on Wednesday announced the retirement of Paul Weagraff, Director of the Division of Arts, following 24 of years of service to the Department of State. Weagraff will serve through the end of July.  “Paul and I have served together through the bookends of two great challenges to our arts community: […]

This year the Division will invest nearly $3 million in more than 100 arts and community organizations Wilmington, Del. (July 8, 2021) – The Delaware Division of the Arts is investing nearly $3 million in more than 100 arts and community organizations that will serve Delawareans statewide with arts programming and services, arts education, and […]

Dover, Del. (July 15, 2021) – The Delaware Division of Small Business and Office of Management and Budget (OMB) announced today the launch of a Market Pressure Relief Fund designed to assist state contractors facing increased costs for construction materials due to the pandemic. The fund will provide adjustment reimbursements for non-transportation construction materials purchased […]

SMYRNA, Del. (August 11, 2021) – A company working to alleviate symptoms of Parkinson’s disease, a maker of wearable cooling protective gear, a specialty running store, and a meadery were among the 15 Delaware small businesses recognized Wednesday as awardees of the third round of Encouraging Development, Growth and Expansion (EDGE) Grants from the state […]

The Division will provide up to $400,000 in matching funds to its FY2022 arts organization grantees in conjunction with the event Wilmington, Del. (November 3, 2021) – The Delaware Division of the Arts is proud to support the arts sector through Delaware’s largest day of giving, Do More 24 Delaware, on March 3-4, 2022. For […]

Dover, Del.—Secretary of State Jeff Bullock has asked Jessica Ball to serve as the next Director of the Delaware Division of the Arts. Ms. Ball most recently served as the Executive Director of the Delaware Arts Alliance and will assume the new role effective November 29th, 2021. “The Division of the Arts plays an integral […]

MIDDLETOWN, Del. (December 16, 2021) – The Delaware Division of Small Business recognized 15 small businesses Thursday as winners of the fourth round of Encouraging Development, Growth and Expansion (EDGE) Grants. Awardees in the latest round of the competition include a company working to alleviate phantom limb pain for amputees, a maker of easy-to-use diagnostic […]

Thirty-six arts organizations and 13 artists have received ARP funds Wilmington, Del. (January 5, 2022) – In Fiscal Year 2021, the Division of the Arts received $753,000 from the National Endowment for the Arts through the American Rescue Plan (ARP) Act. With this special award, the Division developed two short-term grant opportunities to help secure […]

The Delaware Division of Small Business is now accepting applications for the Site Readiness Fund from qualified businesses or local governments. Established through Senate Bill 127, the fund promotes economic growth and stability by investing in the development or improvement of commercial and industrial sites to attract job-creating businesses. The Site Readiness Fund provides grants, […]

Twenty-five Delaware artists to receive recognition Wilmington, Del. (January 13, 2022) – Twenty-five Delaware artists are being recognized by the Division for the high quality of their artwork. Work samples from 132 Delaware choreographers; composers; musicians; writers; and folk, media and visual artists were reviewed by out-of-state arts professionals, considering demonstrated creativity and skill in […]

Five of the month's six events celebrate the invaluable contributions that the Black community has made to the culture and history of the United States.

The Division will provide up to $400,000 in matching funds to its FY2022 arts organization grantees in conjunction with the event Wilmington, Del. (February 1, 2022) – The Delaware Division of the Arts is proud to support the arts sector through Delaware’s largest day of giving, Do More 24 Delaware, on March 3-4, 2022. For […]

WILMINGTON, Del. – Governor John Carney and the Delaware Division of Small Business announced Thursday more than $7.7 million in funding awards to seven organizations as part of the recovery effort for the travel, tourism, and outdoor recreation industries.  The funds are part of the Economic Development Administration’s (EDA) $750 million American Rescue Plan Travel, Tourism […]

More than 200 state employees and their family members have registered to show artwork at Delaware State University Art Center/Gallery Dover, Del. (February 16, 2022) – The Delaware Division of the Arts is hosting the 11th annual Delaware State Employee Art Exhibition. The free exhibition will be open to the public from February 21 to […]

Ten Delaware high school students to compete for the state title and to advance to virtual National Finals MEDIA ADVISORY March 2, 2022 WHAT: Ten Delaware high school students participated in the taped state finals for Poetry Out Loud: National Recitation Contest that will premiere on the Delaware Division of the Arts’ YouTube channel. The […]