NIH Launches $500 Million Contest to Produce Best COVID-19 Test
Title: NIH Launches $500 Million Contest to Produce Best COVID-19 Test
Category: Health News
Created: 4/29/2020 12:00:00 AM
Last Editorial Review: 4/30/2020 12:00:00 AM
Title: NIH Launches $500 Million Contest to Produce Best COVID-19 Test
Category: Health News
Created: 4/29/2020 12:00:00 AM
Last Editorial Review: 4/30/2020 12:00:00 AM
The importance of noncoding RNA sequences has become increasingly clear over the past decade. New RNA families are often detected and analyzed using comparative methods based on multiple sequence alignments. Accordingly, a number of programs have been developed for aligning and deriving secondary structures from sets of RNA sequences. Yet, the best tools for these tasks remain unclear because existing benchmarks contain too few sequences belonging to only a small number of RNA families. RNAconTest (RNA consistency test) is a new benchmarking approach relying on the observation that secondary structure is often conserved across highly divergent RNA sequences from the same family. RNAconTest scores multiple sequence alignments based on the level of consistency among known secondary structures belonging to reference sequences in their output alignment. Similarly, consensus secondary structure predictions are scored according to their agreement with one or more known structures in a family. Comparing the performance of 10 popular alignment programs using RNAconTest revealed that DAFS, DECIPHER, LocARNA, and MAFFT created the most structurally consistent alignments. The best consensus secondary structure predictions were generated by DAFS and LocARNA (via RNAalifold). Many of the methods specific to noncoding RNAs exhibited poor scalability as the number or length of input sequences increased, and several programs displayed substantial declines in score as more sequences were aligned. Overall, RNAconTest provides a means of testing and improving tools for comparative RNA analysis, as well as highlighting the best available approaches. RNAconTest is available from the DECIPHER website (http://DECIPHER.codes/Downloads.html).
Newly released FBI documents suggest a federal judge in Washington was swayed by apparent misrepresentations from a top prosecutor when he issued a memorandum opinion in December 2019 -- a ruling that marked one of the lowest points in former U.S. national security adviser Michael Flynn's effort to withdraw a guilty plea on a charge of lying to investigators.
In today's Diary: Unofficial Eurovision replacement planned / David Nicholls on his unkind friend / Robert Halfon has too many Whatsapp groups / Simon Hoare creates new barnet formula
NASA has awarded the University of Washington a $499,864 grant to develop a competition that calls on students to turn a simulated lava tube into a habitat suitable for harboring humans on the moon or Mars. The exploration and habitation skills competition will be funded as part of NASA's Artemis Student Challenges program, which plays off the themes of the Artemis moon program to inspire the next generation of explorers and engineers. The competition will involve navigating a rover through a facsimile lava tube and surface structures, generating maps, identifying valuable resources and deploying an airtight barrier to seal the… Read More
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The Workers Compensation Commission finds in favour of a former House Rules contestant who claimed she was now unemployable because of the negative way she was portrayed on the Channel Seven show.
Saray Carrillo felt she was being unfairly treated by the judges on the Spanish version of MasterChef - so decided to cook up a terrifying meal in revenge
Mental health advocate Malin Andersson reacted to the news that the ITV2 dating show has been shelved
A former officer and two employees of Teamsters Local 743 (Local 743) were convicted today in federal court in Chicago of federal labor fraud and theft charges in connection with stealing union ballots in an effort to rig two elections in favor of an incumbent slate of officers in 2004. A federal jury returned guilty verdicts today, after deliberating since April 29, 2009, against the three defendants whose trial began on April 6, 2009.
The winner of the APEC Photo Contest 2019 has also won the most votes for the Popular Choice Award, announced the APEC Secretariat.
In last night’s Pennsylvania primary, Hillary Clinton won a sweeping if not quite overwhelming victory, receiving 55 percent of the vote and reducing Barack Obama’s overall popular vote edge by more than 200,000. Because of the Democratic party’s system of proportional representation, she netted fewer than 15 pledged delegates. These results have quieted calls for her to leave the race and will probably slow the steady flow of superdelegates to Obama. Nonetheless, her path to the nomination remains steep.
The demographics of the Pennsylvania vote followed a now-familiar pattern. Obama won among voters younger than 40, while Clinton prevailed among older voters. Obama won in big cities and some inner suburbs; Clinton carried suburbs overall while winning more than 60 percent of the small town and rural vote. Clinton did 9 points worse among men than among women, who constituted 59 percent of last night’s voters. She received 62 percent of the vote from gun-owning households and almost three-fifths of the vote from union households. Obama carried voters from families making less than $15,000 and more than $150,000; Clinton carried everyone in between. She received 64 percent of the vote from high school graduates but only 48 percent from college graduates. Obama won 55 percent of the vote among those who consider themselves “very liberal,” while Clinton got 60 percent of the vote among self-described moderates. Clinton took 56 percent among long-time Democrats, while Obama took 62 percent of new Democratic primary voters—principally Republicans and Independents who registered as Democrats to participate, but also the 4 percent of the primary electorate that previously been unregistered.
There is evidence that religion, gender and race all figured in the results. Clinton received 58 percent of the white Protestant vote and a stunning 71 percent of white Catholics. Obama got 64 percent of those who profess no religion and 56 percent of those who never attend church. Clinton did 22 points better among those who said gender was important than among those who did not. (Intriguingly, men who said it mattered were also more likely to support Clinton.) By contrast, race appears to have been a negative for Obama: whites who said it mattered gave 75 percent of their votes to Clinton, versus only 58 percent for those who said it did not. While nearly half the whites for whom race mattered refused to say that they would be willing to support Obama in the general election, their sentiments may well soften in coming months as differences between the parties come to the fore.
The long campaign mattered, and it left some bruises. 68 percent of the voters said that Clinton had attacked unfairly; 50 percent thought Obama had. Nearly a quarter of the electorate thought that Clinton was solely responsible for unfair attacks, versus only 6 percent who thought Obama was. Only 57 percent of the electorate thought that Clinton was honest and trustworthy, versus 67 percent for Obama. Only 40 percent said they would be satisfied if either candidate won; 32 percent wanted only Clinton, and 23 percent only Obama. But however negative the contest may have turned, it appears to have worked to Clinton’s advantage: she received 57 percent among voters who decided during the last week before the primary, 5 points better than she did among those who decided earlier.
The results also confirmed the surge in concern about the economy. Fifty-five percent of the voters regarded the economy as the top issue, versus only 27 percent for the war in Iraq and a modest 14 percent for health care. Obama prevailed only among voters who gave top priority to Iraq, while Clinton received 54 percent of the health care voters and 58 percent of the economy voters.
Attention now shifts to the May 6 primaries in North Carolina and Indiana. Obama is expected to prevail in North Carolina, but Indiana offers a level playing field. A split decision would be likely to prolong the race, while an Obama sweep might well induce many undecided superdelegates to declare for him and bring this protracted contest to an end. In addition, Obama’s fundraising edge is becoming increasingly important. Not long into her victory speech, Clinton made an urgent pitch for new contributions. Facing a mounting debt and dwindling cash on hand, her ability to continue on until the end of the primary and caucus season in early June may well depend on the size and speed of her supporters’ response.
As President Obama said during his recent address at the African Union, "There's a lot that I'd like to do to keep America moving. But the law is the law, and no person is above the law, not even the president." This sentence, uttered during his speech to the African Union last month, summarizes President…
Once again, we're proud to partner with the United Nations Environment Programme to help fight food waste and bring attention to World Environment Day.
Did you know that 50% of food produced is wasted? It is true, but thankfully, the United Nations Environment Program and TreeHugger are helping shine a light on this problem with our fourth annual World Environment Day Blogging Competition.
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Each month presents a new culinary challenge. Submit an entry and you could win a trip to Spain.
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The Crisis of Civilization explores our modern cultural crises by sampling archive film footage from PSAs. Now the makers are asking budding film makers to have a go themselves.
In honor of what would have been Rachel Carson's 100th birthday, the U.S. Environmental Agency has an essay/poetry/photo contest for two-person teams. The famed writer and biologist once wrote about the need for children and adults to share the "joy,
Calling all ocean lovers and shutterbugs, the 11th edition of this fabulous photo contest is accepting submissions.
Distressing photos received by the Ocean Conservancy show just how helpless marine animals are in the face of drifting nets.
There's just a few more days to submit your project to this fun contest, with the chance to win some great prizes!
Every year, people go crazy buying coffee and tossing the cups, in hopes of winning a prize. It's a ludicrously antiquated model.
The votes are in and these are the top 10 finalists in the 2012 World Environment Day Blogging Contest! Read their posts and vote for the winner!
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Time is running out to enter! Win a trip to Mongolia for World Environment Day by entering our annual contest!
The headline says it all! Let’s dive right in. Costume Contest We had such fun with our Fanart Contest that we want to honor another section of the Dresden fandom’s creatives: cosplayers and cosplay photographers! Read all the rules, then submit your Cosplay Contest entries to yearofdresden@gmail.com by May 12th. Coloring Pages Running low on [...]
The big draw this week is our fourth Microfiction, but there’s plenty more to get excited about! We’ve got the Dresden Files Cooperative Card Game’s debut on switch, an upcoming Trailer Rewatch event, a $1.99 ebook deal on Death Masks, and more. It’s also the last week to submit your costumes for our contest. Read [...]
21-year-old YouTuber and lifestyle blogger, Danish Zehen died an unfortunate death on December 20. The news came as a shocker to many as Danish was the participant of the show, Ace of Space. Reportedly, he died in a car accident on Thursday morning.
Apparently, the accident took place on the Vashi highway. The visuals of the accident and the entirely damaged car have surfaced online.
According to Mankhurd Police, who are investigating the accident, the 21-year-old lifestyle blogger was returning home after attending a wedding when his car met with an accident. Zehen, a resident of Kurla, was immidiately taken to the Fortis hospital Vashi where he succumbed to injuries.
The Mankhurd police has registered an ADR in the case and are currently investigating the matter.
Over the last few years, Zehen had amassed a massive following on YouTube and Instagram thanks to several viral posts. With a following of more than 3 lakh, his fans are pouring condolences and praying for his family to cope up with their unbearable loss. Danish had made an appearance in ex-Bigg Boss contestant Vikas Gupta's reality show, Ace of Space.
A few hours ago before this accident, Danish had shared a few stories on Instagram, while he was driving. The 21-year-old left the reality show in the first week of December and assured that he would return back to the show.
View this post on InstagramDekhte hu mujhko tujhse pyaar hogaya â¤ï¸ÂÂÂâ¤ï¸Â #coolestbadboi
His mass popularity and fan following also won him several brand endorsements. Among them was Gillette, for which he was the digital brand ambassador.
With inputs from Anamika Gharat
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The outbreak of coronavirus has made it difficult for people to get treated for other illnesses without being a COVID-19 suspect. However, the Bigg Boss 2 contestant, Sambhavna Seth who is well known for her vlogs, was rushed to the hospital in the dead of the night. Her husband, Avinash Dwivedi, took to Sambhavna’s Instagram to inform her fans of the situation.
According to Avinash’s message, Sambhavna had to be rushed to the hospital twice. When she was unwell a couple of days ago, her husband accompanied her to Kokilaben Dhirubhai Ambani Hospital and the couple came back home at 5 am. However, they took her back to the hospital again. While her fans were extremely worried about her health, Sambhavna spoke to a portal and clarified the reason behind it. She said that her blood pressure dropped low and she fainted, she is also suffering from a severe ear infection and her ear is completely blocked.
View this post on Instagram
She further spoke about the stress they had to go through to get her admitted to a hospital. Sambhavna clarified that no hospital opened its gates till 4 in the morning. She tried a few hospitals before the staff at Kokilaben attended her and asked her to leave soon after the treatment, which is why she had to go back again.
In 2017, Aamir Khan started a project to boost budding writers in the Indian film industry. The second edition of Cinestaan India's Storyteller Script Contest, a nationwide hunt for scripts where the five winners take home a total cash prize of Rs. 50 lakh was launched this February. From the past few months, the four-member jury consisting of Aamir Khan, Anjum Rajabali, Juhi Chaturvedi and Rajkumar Hirani has gone through numerous entries to choose five compelling stories that can be taken to screen.
However, this time instead of the on-ground event to announce the winners, Aamir Khan will unveil the winners on social media. Meanwhile, Khan is urging writers to not let the prevailing situation dampen their creativity. He said that budding writers should write with more enthusiasm, especially during these times.
Says Rohit Khattar, Chairman of Cinestaan Digital, “I am grateful to our esteemed jury in working with us to bring Indian storytelling talent to the forefront especially during these surreal times. Thank you to the thousands of writers who had applied. The quality of the work was stellar and we would like to congratulate the winners who are truly deserving and wish them success.”
Speaking about the winners, Anjum Rajabali, the Jury Chairperson said, ‘We started this contest with the larger objective of attracting more people to write scripts. It’s very important that we improve the quality of our scriptwriting so that the quality of our cinema goes up. The caliber of scripts in this edition was better than last year and it’s heartening to see that the talent is developing. Thank you to the jury members for giving their valuable time in reading and assessing the scripts. Truly appreciate the Cinestaan team’s hard work. I have not seen this kind of unconditional support and generosity before, with the only reward being to encourage good writing in this country.’
Juhi Chaturvedi says, ‘As a writer, I understand the joy of being appreciated, especially on a big platform like this which motivates us to write more. Congratulations to the winners. I’m very happy that through this contest I was able to be a small part of your journey.’
Raju Hirani while congratulating the winners said, ‘I’m happy that the objective with which this contest was started, to inspire scriptwriters and give them a platform to send their scripts from all parts of the country - slowly and steadily we are moving towards our goal. The caliber of scripts this year has been better than last year.’
All the entries of the second edition of the contest went through a transparent and stringent process of evaluation at various levels. The shortlisted synopsis were asked to send in a complete script which were then assessed and then the winners selected by the jury. All scripts have been registered by the contestants with the Scriptwriters Association and other similar recognized bodies to ensure that the writers' content is completely protected.
‘Cinestaan India’s Storytellers Script Contest’ was launched by Cinestaan Digital Pvt. Ltd. and is India’s biggest Script Contest. The winners of the contest are awarded cash prizes worth Rs. 50 lakhs.