This morning I took (early) delivery of Amazon’s new Kindle 3 – I opted for the WiFi only version – a device that claims 50% better contrast than any other e-reader, a 21% smaller body while keeping the same 6″ size reading area, and a 20% increase in the speed of page turns. These are, [...]

velocityconf: What Is the Risk That Amazon Will Go Down (Again)? http://t.co/DgnfQynjcM Thank you @bergstrom_johan for the awesome #velocityconf post.

Eight suspected illegal miners, known as zama zamas, have been arrested in Limpopo, following a Hawks investigation.

Stay up to date with the latest news, views and analysis as the number of coronavirus cases in SA increases.

With the working class resorting to online vouchers for groceries and the poor eating less bread than before, is it not impractical for the president to expect ordinary citizens to tighten their belts when MPs, Ministers and government officials' well-fed bellies belie the trouble the economy is in?

“In a COVID world, bluntly, it didn’t make sense to continue that pilot,” Realogy’s CEO said during its earnings call Thursday.

Theme Cruise to Panama (Shakespeare at Sea / MacMania)

Amateur Traveler Live Dial-in Show

Amateur Traveler Live Dial-in Show

The Bahamas

Hear about travel to Panama as the Amateur Traveler talks to Chaundra from London about her recent trip to that country. She spent a week in Panama before a SilverSeas Silver Explorer cruise in the area to see wildlife. As part of the cruise they visited the Pearl Islands as well as the Darien Gap. On their own they visited Panama City, the Old Panama City, Casco Viejo, Fort Sherman, Colon and Soberania and Chagres National Parks.

Hear about travel to Mobile, Alabama as the Amateur Traveler talks to Carla Rountree from theinconsistentnomad.com about her home state. There are beautiful beaches. It is an area that was founded in the early 1700s so there is lots of culture, lots of history and it is even the area where Mardi Gras actually started in the USA. 

Hear about travel to the Tennessee River Valley as the Amateur Traveler talks to Chuck Prevatte from foodwinebeertravel.com about the region from Chatanooga, Teneesee to Huntsville, Alabama.

Hear about travel to Naples and the Amalfi Coast in Italy as the Amateur Traveler talks to Beth Rubin from SelectItaly.com about how to plan a trip to this beautiful region. 

Hear about travel to India as the Amateur Traveler talks to participants from the Amateur Traveler trip to India in November of 2017. 

Hear about travel to Jamaica as the Amateur Traveler talks to Dave and Deb from theplanetD.com about their trips to the island.

Hear about travel to the Guna Yala region of Panama as the Amateur Traveler talks to Lynn Smith from lynnsmithdestinations.com about a small boat cruise in these remote islands.

Hear about travel to Alabama as the Amateur Traveler talks to travel writer Larry Bleiberg about his adopted home state.

Conservatives had this Common Core thing all wrong, it was said. We’d be proven wrong by history. Common Core, pushed by President Barack Obama, was going to work. It wasn’t like all the other liberal education plans. A new study by the Pioneer Institute reveals that, no, we were right all along. The study, released…

The post New Study Confirms We Were Right: Reading, Math Scores Have Collapsed Thanks to Obama, Common Core appeared first on The Western Journal.

Unless the Supreme Court acts fast, the window might be closed for President Obama on immigration reform.

'Hollywood' actor Samara Weaving lets us in on all of the movies and television she's been watching during quarantine.   Read more...

Hi, Amazon. We’ve had a long history, ever since I ordered those first books and DVDs to be delivered to my college mailbox. You indulged my whims, from paleo cooking to crocheting, and you deposited a solid amount of cash in my bank account at the end of every month. Not to mention that fat …

Dear Amazon, We’re Breaking Up. It’s Not Me. It’s You. Read More »

The post Dear Amazon, We’re Breaking Up. It’s Not Me. It’s You. appeared first on Adventurous Kate.

The DML News App offers the best in news reporting.

The post REPORT: Obama rips Trump over coronavirus in private call appeared first on Dennis Michael Lynch.

The following article, BREAKING: Sen Marsha Blackburn Introduces Stop COVID Act…Allowing US Citizens To Sue Communist China For Damage They’ve Inflicted On Our Nation, was first published on 100PercentFedUp.com.

Yesterday, Senator Marsha Blackburn (R-TN), along with Senator Martha McSally (R-AZ) introduced the Stop COVID Act, giving Americans the ability to sue Communist China for the damage they’ve inflicted on our nation. Senator Blackburn appeared on Fox News with host Judge Jeanine where she explained the act to Jeanine Pirro. Blackburn told the Fox News […]

Continue reading: BREAKING: Sen Marsha Blackburn Introduces Stop COVID Act…Allowing US Citizens To Sue Communist China For Damage They’ve Inflicted On Our Nation ...

The following article, Attorney for Jailed Dallas Salon Owner Shelley Luther Slams Obama Loyalist Judge as a “Tiny Tyrant”, was first published on 100PercentFedUp.com.

Warren Norred, attorney for Shelley Luther, joined Tucker Carlson to discuss the decision by an Obama loyalist Texas judge to jail his client for reopening her salon during the COVID-19 pandemic. Norred said the judge has exposed himself for the “tiny tyrant” that he is. The judge jailed Luther and even fined her $7,000. Texas […]

Continue reading: Attorney for Jailed Dallas Salon Owner Shelley Luther Slams Obama Loyalist Judge as a “Tiny Tyrant” ...

The following article, Video Scrubbed of Obama-Biden Ambassador To China Praising Their Response to Coronavirus: “I take my hat off to China”, was first published on 100PercentFedUp.com.

During a recent interview on CNN, Obama-Biden ambassador to China (2014-2017) Max Baucus compared standing up to China on the coronavirus to “Hitler in the ’30s.” Baucus has proven himself to be sympathetic to China in recent interviews, where he puts down America and praises the Chinese. The MSNBC video via The Washington Free Beacon […]

Continue reading: Video Scrubbed of Obama-Biden Ambassador To China Praising Their Response to Coronavirus: “I take my hat off to China” ...

The following article, Video: Salon Owner Shelley Luther Released from Jail After Obama-Loyalist Judge Sentenced Her to 7 Days, was first published on 100PercentFedUp.com.

Salon A La Mode owner Shelley Luther was just released from jail today. The Texas Supreme Court and Texas Governor Greg Abbott both called for her release today (see below). When Luther left jail she was greeted by supporters who yelled “Shelley’s Free!” She thanked all of the new friends she’s made during this difficult […]

Continue reading: Video: Salon Owner Shelley Luther Released from Jail After Obama-Loyalist Judge Sentenced Her to 7 Days ...

The following article, Mother of the Year, Michelle Obama Explains How Having Kids Was A “Concession”… Had To Give Up Her “Aspirations and Dreams” [VIDEO], was first published on 100PercentFedUp.com.

While campaigning for her community organizer turned presidential candidate husband, Barack, Michelle Obama told a crowd of his supporters in Milwaukee, Wisconsin that for the first time in her life, she was proud to be an American. Four years later, Michelle Obama was a keynote speaker at the DNC convention, where she told Democrats how […]

Continue reading: Mother of the Year, Michelle Obama Explains How Having Kids Was A “Concession”… Had To Give Up Her “Aspirations and Dreams” [VIDEO] ...

The following article, BREAKING: New Docs Prove Obama Knew Details Of Flynn Wiretapping…Newly Surfaced Video Shows Obama Explaining How He Stays Out Of FBI Investigations, was first published on 100PercentFedUp.com.

Barack Obama knew. Documents released yesterday that were used to exonerate President Trump’s new NSA General Flynn, prove that President Barack Obama was aware of the details of Michael Flynn’s intercepted phone calls on December 16 with then-Russian Ambassador Sergey Kislyak. On January 5, 2017, then-Deputy Attorney General, Sally Yates attended an Oval Office meeting […]

Continue reading: BREAKING: New Docs Prove Obama Knew Details Of Flynn Wiretapping…Newly Surfaced Video Shows Obama Explaining How He Stays Out Of FBI Investigations ...

The following article, Obama Private Call Released: Implores Political Operatives to Help Protect Him…”We gotta make this happen”, was first published on 100PercentFedUp.com.

Michael Isikoff at Yahoo News on Friday night released audio of a call from former President Barack Obama to political operatives and the media to help protect “the rule of law” by protecting him. Obama desperately wants the Deep State and media to protect him by helping elect Joe Biden: “The fact that there is […]

Continue reading: Obama Private Call Released: Implores Political Operatives to Help Protect Him…”We gotta make this happen” ...

Members Event Screening Room

Event participants

Dr Hamza Al Kateab, Director, AlQudes Hospital, Aleppo (2012-16); Operation Manager, Huozhi
Rita Dayoub, Academy Associate, Centre on Global Health Security, Chatham House; Founder, Health Workers at the Frontline Initiative
Dr Husam Taha El-mugamar, Vice President, Sudan Doctors’ Union UK
Chair: Elham Saudi, Director, Lawyers for Justice in Libya

Incorporation of ribonucleotides into DNA can severely diminish genome integrity. However, how ribonucleotides instigate DNA damage is poorly understood. In DNA, they can promote replication stress and genomic instability and have been implicated in several diseases. We report here the impact of the ribonucleotide rATP and of its naturally occurring damaged analog 1,N6-ethenoadenosine (1,N6-ϵrA) on translesion synthesis (TLS), mediated by human DNA polymerase η (hpol η), and on RNase H2–mediated incision. Mass spectral analysis revealed that 1,N6-ϵrA in DNA generates extensive frameshifts during TLS, which can lead to genomic instability. Moreover, steady-state kinetic analysis of the TLS process indicated that deoxypurines (i.e. dATP and dGTP) are inserted predominantly opposite 1,N6-ϵrA. We also show that hpol η acts as a reverse transcriptase in the presence of damaged ribonucleotide 1,N6-ϵrA but has poor RNA primer extension activities. Steady-state kinetic analysis of reverse transcription and RNA primer extension showed that hpol η favors the addition of dATP and dGTP opposite 1,N6-ϵrA. We also found that RNase H2 recognizes 1,N6-ϵrA but has limited incision activity across from this lesion, which can lead to the persistence of this detrimental DNA adduct. We conclude that the damaged and unrepaired ribonucleotide 1,N6-ϵrA in DNA exhibits mutagenic potential and can also alter the reading frame in an mRNA transcript because 1,N6-ϵrA is incompletely incised by RNase H2.

• Review of Mama
• What We Watched: The Last Stand, Tangled, Silent Hill: Revelations, Bob's Burgers, South Park, Arrested Development and The Hole. 

Expert

THERE'S nothing like the sweet taste of victory, especially when it's long in coming.

In-form American sprinter, Michael Rodgers, ran a world-leading 9.94 seconds and there were no Caribbean