way Bermuda Flag Football League Underway By bernews.com Published On :: Tue, 03 Sep 2019 09:32:46 +0000 The Bermuda Flag Football League Season got underway on the T.N. Tatem Middle School Field with 18 points put on the board in a single match. The Punishers defeated the Renegades 12 – 6, Jared Jimenez led the Punishers with two offensive touchdowns, while the Renegades saw Jacqueline Oliver record four sacks. Related Stories Punishers […](Click to read the full article) Full Article All Sports #AmericanFootball
way Mitchell Finishes 6th At Walton Raceway By bernews.com Published On :: Sun, 18 Aug 2019 12:41:15 +0000 Bermuda’s Jyire Mitchell continued competing for Team Holeshot Motor Sports on the Canadian MX Circuit. The Professional Eighth Round Moncton Division Triple Crown Race took place at the Walton Raceway. In the Moncton 250cc Division, Mitchell finished 6th overall; he finished 8th in the First Moto and then finished 5th in the Second Moto. Mitchell […](Click to read the full article) Full Article All Sports #Motocross #MotorcycleRacing
way Scott Barnes Wins On Daytona Motor Speedway By bernews.com Published On :: Mon, 31 Dec 2018 15:41:32 +0000 Scott Barnes concluded competing at the World Karting Association’s Daytona Kart Week at the Daytona Motor Speedway, making an excellent showing to finish on top of the podium in the Stock Honda 125 Class during the second day of racing. Barnes clocked an 8 lap winning time of 20:26.765, with his fastest lap being the 7th […](Click to read the full article) Full Article All Sports #GoodNews #Karting
way Bermuda Karting Club Race Season Underway By bernews.com Published On :: Mon, 21 Oct 2019 22:58:15 +0000 The Bermuda Karting Club race season got underway at the Southside Motor Sports Park in St. George’s. Scott Barnes won all three races in the Tag Senior Class, while Jason North won all three races in the L206 Masters Class. David Barbosa won two of the three races in the L206 Senior Class, while Jorja […](Click to read the full article) Full Article All Sports #Karting
way Faulkenberry Returns To Broadway In Crime Film By bernews.com Published On :: Tue, 08 Oct 2019 11:56:35 +0000 Bermudian actress and singer Rebecca Faulkenberry is heading back to Broadway, but this time in an epic new crime film rather than a musical theatre stage show. Ms Faulkenberry, who has appeared in the Broadway productions of Rock of Ages, Spider-Man: Turn Off The Dark and Groundhog Day is featured in The Irishman, the new […](Click to read the full article) Full Article All Entertainment Films/Movies News #Film #FullLengthMovies #GoodNews #RebeccaFaulkenberry
way Turtle Project’s 2019 Field Trip Underway By bernews.com Published On :: Thu, 22 Aug 2019 09:44:26 +0000 The Bermuda Turtle Project, one of the oldest ecological studies of its kind on the island, is this summer beginning its second half-century of research and conservation initiatives aimed at protecting our sea turtles. Established in 1968 by the Bermuda Aquarium, Museum & Zoo in collaboration with the Florida-based, environment-friendly Sea Turtle Conservancy international charity, […](Click to read the full article) Full Article All Environment #Animal #BermudaMarine #Turtles
way Photos & Video: Work Underway On NSC Track By bernews.com Published On :: Thu, 30 Jan 2020 19:26:14 +0000 Contractors have started prepping and applying the polyurethane levelling material to the surface of the 400-metre running track at the National Sports Centre. The original track was laid in 2001/2002 and has fallen into disrepair and with the NSC due to host the Carifta Games in April, a decision was made to have it resurfaced. […](Click to read the full article) Full Article All News Photos Sports Videos #BermudaTrackAndField
way Appleby Hires Rebecca Holloway & Joy Martin By bernews.com Published On :: Thu, 12 Mar 2020 16:11:29 +0000 Appleby Bermuda has welcomed Bermudians Rebecca Holloway and Joy Martin as compliance officers within the compliance team. Ms Holloway graduated from Bristol University with a Bachelor of Arts degree in French and Spanish. Ms Holloway is a Certified Anti-Money Laundering Specialist [CAMS] and Certified Financial Crime Specialist [CFCS]. Prior to joining Appleby, she served as a […](Click to read the full article) Full Article All Business News #Appleby #BermudaBusiness #BusinessExecutives
way Powerboat Racing Season Set To Get Underway By bernews.com Published On :: Mon, 02 Apr 2018 15:23:31 +0000 The upcoming Bermuda Powerboat Association [BPBA] season is set to get underway. After a team test day in April, the first race day is scheduled for May 13th at Ferry Reach. Action is expected to start at 12.00pm on race days. Video from last year’s Around The Island Race. A spokesperson said, “The BPBA Executive […](Click to read the full article) Full Article All Sports #GoodNews #PowerboatRacing
way Videos: Around The Island Race Gets Underway By bernews.com Published On :: Sun, 12 Aug 2018 16:29:09 +0000 The final preparations are underway for the Rubis Around the Island powerboat race which is set take place this afternoon [Aug 12] starting from Ferry Reach in the east end. We will have additional coverage later on, and in the meantime, the live video is below. The live broadcast of the final preparations has ended, […](Click to read the full article) Full Article All News Sports Videos #AroundTheIslandBoatRace #GoodNews #PowerboatRacing #SportsVideos
way Photos & Video: British Airways i360 Tower By bernews.com Published On :: Wed, 24 Aug 2016 16:20:08 +0000 [Written by Don Burgess] Bermuda residents will be able to use British Airways’ new arrival and departure areas at Gatwick starting on January 24. That is the day BA will move from the North Terminal to the South Terminal and offer up a better travel experience for fliers. Colm Lacy, head of Commercial British Airways Gatwick, […](Click to read the full article) Full Article Airport/Planes All News Photos Videos #Airlines #Airport #DonBurgessReports #UnitedKingdom
way Photos: British Airways’ Flight Simulator By bernews.com Published On :: Fri, 26 Aug 2016 10:38:23 +0000 [Written by Don Burgess] Have you ever dreamed of piloting a multi-million dollar airliner? British Airways is giving people a chance to experience the thrill of being in the cockpit of one of its planes through its flight simulator. The facility, which is located in London, could make your next travel to the UK a thrilling […](Click to read the full article) Full Article Airport/Planes All Business Photos #DonBurgessReports
way Photos, Video: British Airways Heritage Collection By bernews.com Published On :: Wed, 31 Aug 2016 09:41:18 +0000 [Written by Don Burgess] British Airways has come a long ways after four small airlines merged to form Imperial Airways limited on March 31, 1924. In the 92 years since then, one man has seen most of the changes the airline has made. Keith Hayward joined the company as a traffic apprentice in 1945 and has […](Click to read the full article) Full Article Airport/Planes All History Photos Videos #AviationHistory #BermudaBusiness #DonBurgessReports
way Bermuda Pool League Season Gets Underway By bernews.com Published On :: Sat, 23 Sep 2017 10:00:02 +0000 The 2017/18 Bermuda Pool League Season got underway across the island. The Bermuda Breeze defeated the Bishops 204 – 150, Bailey’s Bay defeated the BAA Bandits 213 – 167, and the Dragons defeated the HWC Pitbulls 218 – 161. The Gladiators defeated RAA 201 – 185, Bailey’s Bay II defeated BPSU 188-185, and Warwick Workmens […](Click to read the full article) Full Article All Sports #Snooker
way Wells: ‘Bermuda Will Always Be Home For Me’ By bernews.com Published On :: Sun, 26 Apr 2020 12:49:35 +0000 Bermudian footballer Nahki Wells recently took over the Bristol City Football Club Twitter account in order to answer questions from fans, with the striker noting that Bermuda “will always be home for me.” In answering a question about Bermuda, Wells said, “I think the last time I was in Bermuda was October or November for […](Click to read the full article) Full Article All News Sports Videos #BermudaFootball #NahkiWells #SocialMedia #SportsVideos
way RUBiS Graded Squash Tournament Underway By bernews.com Published On :: Wed, 16 Oct 2019 12:28:09 +0000 The 2019 RUBiS Graded Squash Tournament is underway, and the results from the first day of competition are below. Tuesday October 15 Results A Division Piers Carr beat Peter Cooper 11-7, 11-9, 11-7 Korin Knights beat Elijah Simmons 11-9, 8-11, 11-7, 11-4 Anaya Smith beat Malcom Woodley 11-5, 11-5, 11-4 Melina Turk beat Mark James […](Click to read the full article) Full Article All Sports #Squash
way Bermuda Tourism Authority: ‘Way We Live Tours’ By bernews.com Published On :: Sat, 05 Oct 2019 15:00:33 +0000 “The Bermuda Tourism Authority has worked so hard with local stakeholders to create experiences this fall that focus on our homes, neighbourhoods and architecture,” the BTA said. A spokesperson said, “Visitors are fascinated with the way we live out here. That’s why the Bermuda Tourism Authority has worked so hard with local stakeholders to create […](Click to read the full article) Full Article All News #BermudaRealEstate #BermudaTourism
way Driver Arrested After Collision On Causeway By bernews.com Published On :: Sat, 07 Dec 2019 12:50:32 +0000 The driver of a car involved in an early morning collision with a truck on the Causeway on Friday [Dec 6] was arrested on suspicion of driving whilst impaired. A police spokesperson said, “The incident occurred at around 6:30am, when a car driven west on the causeway by a female occupant, collided with a truck […](Click to read the full article) Full Article Accidents and fires All News #Collision #DrunkDriving
way Minister Wayne Caines On Recent Shootings By bernews.com Published On :: Mon, 17 Feb 2020 00:25:05 +0000 “We will not let the destructive few wreak havoc in our community,” said Minister of National Security Wayne Caines today, following a series of shooting incidents this week, with the most recent happening this morning. Minister Caines added, “All of Bermuda should be outraged that gun shots are being sprayed indiscriminately into to private residences. […](Click to read the full article) Full Article All Crime News #BermudaPolitics #CrimeInBermuda #Shootings
way Evaluating the Suitability of Roadway Corridors for Use by Monarch Butterflies By www.trb.org Published On :: Wed, 22 Apr 2020 13:00:58 GMT The charismatic and familiar monarch butterfly serves as a flagship species for pollinator conservation, and gives rights-of-way entities opportunities to engage a diverse array of stakeholders who are invested in not only restoring monarch numbers to sustainable levels, but also mitigating many other environmental and economic issues. This pre-publication draft of the TRB National Cooperative Highway Research Program's NCHRP Research Report 942 Pre-Pub: Evaluating the Suitability of Roadway Corridors fo... Full Article http://www.trb.org/Resource.ashx?sn=cover_nchrp_rr_942
way Highway Capacity Manual, Sixth Edition: A Guide for Multimodal Mobility Analysis By www.trb.org Published On :: Mon, 27 Apr 2020 11:54:52 GMT Now available to order from the TRB Bookstore, the Highway Capacity Manual, Sixth Edition: A Guide for Multimodal Mobility Analysis (HCM) provides methods for quantifying highway capacity. In its current form, it serves as a fundamental reference on concepts, performance measures, and analysis techniques for evaluating the multimodal operation of streets, highways, freeways, and off-street pathways. The Sixth Edition incorporates the latest research on highway capacity, quality of service, Active Traffic... Full Article http://www.trb.org/Resource.ashx?sn=HCM6cover
way Buy America Requirements for Federal Highway Projects By www.trb.org Published On :: Fri, 01 May 2020 11:55:49 GMT The Federal Highway Administration's “Buy America Act” requires federally funded highway projects to use only steel, iron, and manufactured products produced in the United States. The TRB National Cooperative Highway Research Program's NCHRP LRD 80: Buy America Requirements for Federal Highway Projects summarizes the intent and application of the provision. It also summarizes the procedure that FHWA has implemented for granting waivers and the impact that court interpretation of such waivers has had on t... Full Article http://www.trb.org/Resource.ashx?sn=cover_nchrp_lrd_80a
way Existing and Emerging Highway Infrastructure Preservation, Maintenance, and Renewal Definitions, Practices, and Scenarios By www.trb.org Published On :: Thu, 23 Apr 2020 13:45:15 GMT The National Cooperative Highway Research Program's NCHRP Web-Only Document 272: Existing and Emerging Highway Infrastructure Preservation, Maintenance, and Renewal Definitions, Practices, and Scenarios provides appendices to NCHRP Report 750, Volume 7: Preservation, Maintenance, andRenewal of Highway Infrastructure . Full Article
way Data to improve roadway safety analysis By www.trb.org Published On :: Thu, 07 May 2020 06:31:41 GMT Exploring Crowdsourced Monitoring Data for Safety , released by the Virginia Tech Transportation Institute Full Article
way Impacts on Practice: Redesigning the Communications Center at Phoenix–Mesa Gateway Airport By www.trb.org Published On :: Wed, 20 Nov 2019 12:49:40 GMT As a reliever airport for the Phoenix Sky Harbor International Airport, Phoenix–Mesa Gateway Airport must keep track of information for nearly 300,000 aircraft operations and 1.4 million passengers a year. To meet this challenge, the airport developed an innovative, digitally connected solution with the help of ACRP Research Report 182: Guidancefor Planning, Design, and Operationsof Airport Communications Centers . The TRB Airport Cooperartive Research Program's ACRP Impacts on Practice 182: Redesigning ... Full Article http://www.trb.org/Resource.ashx?sn=cover_acrp_iop_182
way International Symposium on Pavement, Roadway, and Bridge Life Cycle Assessment* By www.trb.org Published On :: Fri, 01 May 2020 05:34:30 GMT University of California Pavement Research and National Center for Sustainable Transport have postponed the International Symposium on Pavement Life Cycle Assessment from June 3-6, 2020 to January 13-15, 2021 in Sacramento, CA. TRB is pleased to cosponsor this event. The symposium will focus on the implementation of Life Cycle Assessment (LCA) for pavements. The workshop address the implementation of LCA in pavement operations at the network and project levels. Full Article
way A Fast Radio Burst Has Been Detected From Inside The Milky Way By www.universetoday.com Published On :: Thu, 07 May 2020 17:39:27 +0000 Fast radio bursts last for such a short time that it is difficult to track down the source. Now astronomers have found one in our own back yard. The post A Fast Radio Burst Has Been Detected From Inside The Milky Way appeared first on Universe Today. Full Article Fast Radio Bursts magnetars Neutron Stars
way Galaxies Like the Milky Way are the Best for Life By www.universetoday.com Published On :: Fri, 08 May 2020 20:06:33 +0000 A new study indicates that, contrary to what has been previously argued, galaxies like our own may be the most likely place to find intelligent life The post Galaxies Like the Milky Way are the Best for Life appeared first on Universe Today. Full Article Astronomy galaxies SETI alien life elliptical galaxies Extrasolar Planets Featured Search for Extraterrestrial Intelligence spiral galaxies
way ACRP Impacts on Practice - Wayfinding and Signing Guidelines for Airports By www.trb.org Published On :: Sun, 03 Jan 2016 20:36:02 GMT The September 2015 issue of TRB’s Airport Cooperative Research Program (ACRP) Impacts on Practice explores how Philadelphia International Airport, Fort Lauderdale-Hollywood International Airport, and Changi Airport in Singapore applied guidance from ACRP Report 52 : Wayfinding and Signing Guidelines for Airport Terminals and Landside to help passengers find their way in and around an airport. Full Article http://www.trb.org/Resource.ashx?sn=IOP2015Septcover
way New Centers Lead the Way towards a Quantum Future By feedproxy.google.com Published On :: Wed, 29 Jan 2020 13:10:01 EST The Department of Energy (DOE) recently announced that it will establish Quantum Information Science Centers to help lay the foundation for these technologies. As Congress put forth in the National Quantum Initiative Act, the DOE's Office of Science will make awards for at least two and up to five centers. Full Article
way Fans Port Mario 64 To PC And Make It Way Better, So Of Course Nintendo Is Trying To Nuke The Project By www.techdirt.com Published On :: Wed, 6 May 2020 19:13:31 PDT I'm lucky enough to own a decades old Nintendo 64 and a handful of games, including the classic Mario 64. My kids love that game. Still, the first thing they asked when I showed it to them the first time is why the screen was letterboxed, why the characters looked like they were made of lego blocks, and why I needed weird cords to plug it all into the flat screen television. The answer to these spoiled monsters' questions, of course, is that the game is super old and wasn't meant to be played on modern televisions. It's the story of a lot of older games, though many PC games at least have a healthy modding community that will take classics and get them working on present day hardware. Consoles don't have that luxury. Well, usually, that is. It turns out that enough folks were interested in modernizing Mario 64 that a group of fans managed to pull off porting it to PC. And, because this is a port and not emulation, they managed to update it to run in 4k graphics and added a ton of modern visual effects. Last year, Super Mario 64's N64 code was reverse-engineered by fans, allowing for all kinds of new and exciting things to be done with Nintendo’s 1996 classic. Like building a completely new PC port of the game, which can run in 4K and ultra-wide resolutions. This is a very new and cool thing! Previously, if you were playing Super Mario 64 on PC, you were playing via emulation, as your PC ran code pretending to be an N64. This game is made specifically for the PC, built from the ground up, meaning it not only runs like a dream, but even supports mod stuff like ReShade, allowing for graphical tweaks (like the distance blur seen here). As you'll see, the video the Kotaku post is referencing can't be embedded here because Nintendo already took it down. Instead, I'll use another video that hasn't been taken down at the time of this writing, so you can see just how great this looks. In addition to videos of the project, Nintendo has also been busy firing off legal salvos to get download links for the PC port of the game taken down from wherever it can find them. Now, while Nintendo's reputation for IP protectionism is such that it would almost certainly take this fan project down under virtually any circumstances, it is also worth noting that the company has a planned re-release of Mario 64 for its latest Nintendo console. That likely only supercharged the speed with which it is trying to disappear this labor of love from fans of an antiquated game that have since moved on to gaming on their PCs. But why should the company do this? Nintendo consoles are known for many things, including user-friendly gaming and colorful games geared generally towards younger audiences. You know, exactly not the people who would take it on themselves to get an old Mario game working on their PC instead of a Nintendo console. What threat does this PC port from fans represent to Nintendo revenue? It's hard to imagine that threat is anything substantial. And, yet, here we are anyway. Nintendo, after all, doesn't seem to be able to help itself. Full Article
way Amazon Sued For Saying You've 'Bought' Movies That It Can Take Away From You By www.techdirt.com Published On :: Thu, 7 May 2020 09:44:56 PDT For well over a decade we've talked about the many problems that arise when copyright is compared to "property" -- and people try to simply move over concepts from physical, tangible property into the world of digital. A key aspect of this: when you "purchase" something digital online, is it really a "purchase" or is it a "license" (especially a license that could be revoked)? If it was a true "purchase" then you should own it and the seller shouldn't be able to take it back. But in practice, over and over and over again, we've seen stories of people having things they supposedly "bought" disappear. The situation is so crazy that we've referred to it as Schrödinger's Download, in that many copyright holders and retailers would like the very same thing to be a "sale" some of the time, and a "license" some of the time (the "times" for each tend to be when it hurts the consumers the most). This has, at times, seeped into physical goods, where they've tried to add "license agreements" to physical products. Or, worse, when some copyright folks claimed that buying a DVD means you don't actually own what you bought, but rather are merely "purchasing access" to the content, and that could be revoked. Anyway, I'm amazed that we don't see more lawsuits about this kind of thing -- but one was recently filed in California. Someone named Amanda Caudel is suing Amazon for saying that you've "purchased" a video download, which Amazon might disappear from your library whenever it wants. As the lawsuit makes clear, Amazon directly says that you are buying the movie (as opposed to renting it). From the lawsuit filing itself: And, they point out, in your account there's a listing of "Your Video Purchases & Rentals." But, the lawsuit claims, what you purchase doesn't seem to behave like a real purchase: Reasonable consumers will expect that the use of a “Buy” button and the representation that their Video Content is a “Purchase” means that the consumer has paid for full access to the Video Content and, like any bought product, that access cannot be revoked. Unfortunately for consumers who chose the “Buy” option, this is deceptive and untrue. Rather, the ugly truth is that Defendant secretly reserves the right to terminate the consumers’ access and use of the Video Content at any time, and has done so on numerous occasions, leaving the consumer without the ability to enjoy their already-bought Video Content. Defendant’s representations are misleading because they give the impression that the Video Content is purchased – i.e. the person owns it - when in fact that is not true because Defendant or others may revoke access to the Video Content at any time and for any reason. In so representing the “Purchase” of Video Content as true ownership of the content, Defendant took advantage of the (1) cognitive shortcuts made at the point-of-sale, e.g. Rent v. Buy and (2) price of the Video Content, which is akin to an outright purchase versus a rental. Though some consumers may get lucky and never lose access to any of their paid-for media, others may one day find that their Video Content is now completely inaccessible. Regardless, all consumers have overpaid for the Video Content because they are not in fact owners of the Video Content, despite have paid extra money to “Buy” the product. The plaintiff (or rather, her lawyers) are trying to make this a class action lawsuit, and are arguing that (among other things) this is false advertising. I am, not surprisingly, sympathetic to the plaintiff -- and remain disappointed at how copyright and similar restrictions are being used to chip away at ownership and actual property rights. That said... I'm not that optimistic the case will get very far. In the past, companies have been able to wiggle out of similar claims, and I'm pretty sure that Amazon tries to push disputes like this to binding arbitration, meaning that the lawsuit may be dead on arrival. Still, it's yet another reminder of how copyright is chipping away at real property. Full Article
way California’s privacy warriors are back – and this time they want to take their fight all the way to the ballot box By go.theregister.co.uk Published On :: Wed, 06 May 2020 22:53:06 GMT Politicos watered down earlier efforts, so data defenders will fight to the end The small group of policy wonks that forced California’s legislature to rush through privacy legislation two years ago are back – and this time they want a ballot.… Full Article
way Dad to kids: I've decided you don't get to take over the family business. Kids to Dad: Who wants to run Samsung anyway? By go.theregister.co.uk Published On :: Thu, 07 May 2020 06:29:06 GMT Lee Jae-yong ends dynastic control and will even let staff join a union Samsung's heir has said that he will not pass down management of the South Korean conglomerate to his children, ending three generations dynastic rule.… Full Article
way BT suspends shareholder payments as folk forgo pricey sports TV deals for matches that won't happen anyway By go.theregister.co.uk Published On :: Thu, 07 May 2020 16:00:06 GMT We all need to tighten our belts For the first time in over three decades, BT has suspended its dividend scheme as the former state-owned teleco grapples with the fallout from the novel coronavirus pandemic, and the financial uncertainty that'll inevitably ensue.… Full Article
way Go on, hit Reply All. We dare you. We double dare you. Because Office 365 will defeat your server-slamming ways By go.theregister.co.uk Published On :: Fri, 08 May 2020 01:12:06 GMT Even Exchange’s marketing bod reckons tests of new Reply-All-stopper could be a career-defining moment Microsoft may just have made Reply All storms a thing of the past, by adding a suitable blocker to Exchange in Office 365 environments.… Full Article
way Backup and restore on AWS is a nightmare – is there a way to speed it up? By go.theregister.co.uk Published On :: Fri, 08 May 2020 17:00:13 GMT Apparently. But we’re so incredulous, we’re gonna test those claims on live internet TV… Webcast “The journey to cloud” echoes through all organisations. It’s a Bildungsroman – a story of empowerment and betterment. A shiny, towering cityscape of gleaming edifices and elegant spires. It’s like an ascension into the actual clouds. Like dying and waking up in heaven.… Full Article
way 09/27/15 - I've always been scared of people like you By www.tinyghosts.com Published On :: Mon, 28 Sep 2015 Full Article
way Featured - How Products are Born: What exactly is going on in research and development anyway? By www.labspaces.net Published On :: Wed, 16 Feb 2011 14:18:06 -0600 OK, let’s pick up our discussion where we left off last week, at feasibility. You did it. You successfully convinced a room full of vice presidents and directors, or maybe even the CEO that they should take your fabulous product idea to the next level. You’ve got marketing on board, excited to promote it and now it’s time for the work to begin.You are the lead scientist s; (read more) Source: Suzy - Discipline: BioTech Full Article
way Stop Throwing Away Those Little Silica Gel Packets! You and the Kids Can Use Them a Ton of Clever Ways By www.freerangekids.com Published On :: Wed, 06 May 2020 02:20:29 +0000 Parents, kids: Fear not the silica gel pack. Sure it says DO NOT EAT and THROW AWAY. But you should only follow one of those rules. Instead, save the packs and use them a whole lot of ways: Place them on the car dashboard by the windshield to keep it from fogging up. […] Full Article Miscellaneous
way CEACAM1 and molecular signaling pathways to expand the liver transplant donor pool By www.jci.org Published On :: Organ shortage continues to limit the lives of patients who require liver transplantation. While extending criteria for liver organs provides a needed resource, tissue damage from prolonged ischemic injury can result in early allograft dysfunction and consequent rejection. In this issue of the JCI, Nakamura et al. used a mouse transplantation model with prolonged ex vivo cold storage to explore liver graft protection. The authors found that liver grafts with absent carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) exhibited increased ischemia-reperfusion injury inflammation and decreased function in wild-type recipients. The authors went on to correlate CEACAM1 levels with postreperfusion damage in human liver transplant recipients. Notably, this study identified a potential biomarker for liver transplant donor graft quality. Full Article
way A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti–PD-1 immunotherapy By www.jci.org Published On :: An in-depth understanding of immune escape mechanisms in cancer is likely to lead to innovative advances in immunotherapeutic strategies. However, much remains unknown regarding these mechanisms and how they impact immunotherapy resistance. Using several preclinical tumor models as well as clinical specimens, we identified a mechanism whereby CD8+ T cell activation in response to programmed cell death 1 (PD-1) blockade induced a programmed death ligand 1/NOD-, LRR-, and pyrin domain–containing protein 3 (PD-L1/NLRP3) inflammasome signaling cascade that ultimately led to the recruitment of granulocytic myeloid-derived suppressor cells (PMN-MDSCs) into tumor tissues, thereby dampening the resulting antitumor immune response. The genetic and pharmacologic inhibition of NLRP3 suppressed PMN-MDSC tumor infiltration and significantly augmented the efficacy of anti–PD-1 antibody immunotherapy. This pathway therefore represents a tumor-intrinsic mechanism of adaptive resistance to anti–PD-1 checkpoint inhibitor immunotherapy and is a promising target for future translational research. Full Article
way Five Ways Maps Can Help Communities Respond to COVID-19 By www.maproomblog.com Published On :: Tue, 07 Apr 2020 22:05:12 +0000 Full Article GIS Health 2019-nCoV coronavirus COVID-19 disease Esri public health
way MacRumors Giveaway: Win an Apple-Themed Plush Pillow From Throwboy By www.macrumors.com Published On :: Fri, 08 May 2020 11:01:17 PDT For this week's giveaway, we've once again teamed up with Throwboy to offer MacRumors readers a chance to win one of Throwboy's plushes modeled after classic Apple products and icons. Throwboy makes a whole range of different plush pillow options priced at $30 to $40, with each one designed to look like an Apple product of some kind, including classic Macs, the iPod, the iPhone, and more. Each pillow features detailed embroidery and careful construction to highlight each component and to accurately represent Apple's designs. The 1998 pillow, for example, is modeled after Apple's original iMac with its bright Bondi Blue design, while the 2001 pillow modeled after the original iPod comes complete with a screen and click wheel embroidery. The 2007 pillow looks like the original iPhone with black bezels and a silver backing, and the Icon Pillow looks like Apple's classic happy Finder icon. There's even a rainbow-colored Spinning Wheel Pillow that's designed to look like the dreaded spinning pinwheel that the cursor morphs into when an application is busy. All of Throwboy's plushes are soft, squishy, huggable, and the perfect accent piece for an Apple fan. Each pillow is the ideal size to be used as a comfortable throw pillow for a couch or a chair. Photos of the pillows in action can be seen on Throwboy's Instagram account. We have 10 of Throwboy's pillows to give away to MacRumors readers, and each winner will be able to pick their favorite pillow: iMac, iPod, classic iPhone, Finder Icon, or Spinning Wheel. To enter to win our giveaway, use the Gleam.io widget below and enter an email address. Email addresses will be used solely for contact purposes to reach the winners and send the prizes. You can earn additional entries by subscribing to our weekly newsletter, subscribing to our YouTube channel, following us on Twitter, following us on Instagram, or visiting the MacRumors Facebook page. Due to the complexities of international laws regarding giveaways, only U.S. residents who are 18 years or older and Canadian residents (excluding Quebec) who have reached the age of majority in their province or territory are eligible to enter. To offer feedback or get more information on the giveaway restrictions, please refer to our Site Feedback section, as that is where discussion of the rules will be redirected. Throwboy GiveawayThe contest will run from today (May 8) at 11:00 a.m. Pacific Time through 11:00 a.m. Pacific Time on May 15. The winners will be chosen randomly on May 15 and will be contacted by email. The winners will have 48 hours to respond and provide a shipping address before new winners are chosen.Tag: giveawayThis article, "MacRumors Giveaway: Win an Apple-Themed Plush Pillow From Throwboy" first appeared on MacRumors.comDiscuss this article in our forums Full Article No AMP giveaway
way Heroes always come home in David Rubín’s free COVID-19 SUPERMAN story (version en español incluída) By www.comicsbeat.com Published On :: Fri, 08 May 2020 18:15:20 +0000 Real heroes deserve their own comics/Los héroes reales merecen sus propios comics The post Heroes always come home in David Rubín’s free COVID-19 SUPERMAN story (version en español incluída) appeared first on The Beat. Full Article Comics DC COVID-19 David Rubin ECC Ediciones en español free comics Jesus Merino Mikel Janin paco roca pandemic
way Twelve Ways Convention Booths Grab Your Attention By www.cockeyed.com Published On :: Thursday, July 28, 2016 11:15:00 GMT Pity the salesman who doesn't have some device to steer people into his booth. Full Article
way Townsville leading the way in improving Australia’s disaster resilience By www.ibm.com Published On :: Wed, 17 Dec 2014 12:46:56 GMT North Queensland capital Townsville is among the first cities globally to use a new United Nations’ Office for Disaster Risk Reduction (UNISDR) disaster resilience scorecard developed jointly by global fully integrated infrastructure firm AECOM and IBM.</p> Full Article Security
way John Conway By terrytao.wordpress.com Published On :: Sun, 12 Apr 2020 20:46:49 +0000 I was greatly saddened to learn that John Conway died yesterday from COVID-19, aged 82. My own mathematical areas of expertise are somewhat far from Conway’s; I have played for instance with finite simple groups on occasion, but have not studied his work on moonshine and the monster group. But I have certainly encountered his […] Full Article obituary coronavirus john conway