Manchester : Manchester University Press, [2022]

Red Bull started the year looking mighty and expected to cruise to the world titles, but now has rivals McLaren and Mercedes breathing down its neck; if McLaren continues its recent form, it could very well clinch its first constructors’ crown since 1998 and knock the reigning champion off its perch

'Bahut mazaa aaya tha doing Agneepath. When you are working with good actors, it enriches your acting.''Amitabhji and I had done Shahenshah before, but that was a fun film.'

New York : Bloomsbury, Bloomsbury Academic, An Imprint of Bloomsbury Publishing Plc, 2016.

Ogilvy UK Vice Chairman Rory Sutherland co-founded a behavioural science practice within the agency, which works with a consulting practice of psychology graduates who look for ‘unseen opportunities’ in consumer behaviour. At WIRED Health, Sutherland explores the psychological reasons why people do things and how perception and placebos can be used for a positive outcome. "It doesn't really matter why people do it so as long as they do," Sutherland points out. "There's a danger in activity which goes 'it's not enough for people to go and do the thing we want them to do, they have to do it for the right reason'. To be honest, I don't really mind if people buy an electric car because they think it's really cool." ABOUT WIRED HEALTH 600 innovators, scientists and business leaders gathered at The Francis Crick Institute in London, for WIRED Health on March 26, 2019. Discover some of the fascinating insights from speakers here: http://wired.uk/health-event ABOUT WIRED EVENTS WIRED events shine a spotlight on the innovators, inventors and entrepreneurs who are changing our world for the better. Explore this channel for videos showing on-stage talks, behind-the-scenes action, exclusive interviews and performances from our roster of events. Join us as we uncover the most relevant, up-and-coming trends and meet the people building the future. ABOUT WIRED WIRED brings you the future as it happens - the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics. CONNECT WITH WIRED Events: http://wired.uk/events Subscribe for Events Information: http://wired.uk/signup Web: http://bit.ly/VideoWired Twitter: http://bit.ly/TwitterWired Facebook: http://bit.ly/FacebookWired Instagram: http://bit.ly/InstagramWired Magazine: http://bit.ly/MagazineWired Newsletter: http://bit.ly/NewslettersWired

Dr. Daniel Amen uses the power of Twitter to answer the internet's burning questions about how the human brain works. Why do we sometimes completely forget common words? Why does our brain seem to work best in the shower? Why is our anxiety through the roof during quarantine? Dr. Amen answers all these questions and much, much more!

Michael Pollan, author of "This Is Your Mind On Plants," answers the internet's burning questions about psychedelics. How does LSD work? What is ego death? How are psychedelics used for addiction therapy? Why are psychedelics so frowned upon? Michael answers all these questions and much more. For more on the pharmacology of plants, read Michael Pollan's latest book THIS IS YOUR MIND ON PLANTS - https://www.penguinrandomhouse.com/books/665612/this-is-your-mind-on-plants-by-michael-pollan/#:~:text=In%20This%20Is%20Your%20Mind,about%20them%20into%20sharp%20relief.

Psychiatrist Dr. Eric Bender answers your questions about mental health from Twitter. Can you develop a personality disorder? Is stress contagious? What does the Rorschach test actually prove? Answers to these questions and many more await—it's Mental Health Support.Check out Dr. Eric Bender's Youtube channel for more analysis of popular TV shows and movies: https://www.youtube.com/@dr.ericbender6371Plus, COMING SOON: Dr. Bender's upcoming podcast Shrinkage which explores mental health in TV, movies, and video games.Director: Lisandro Perez-ReyDirector of Photography: Yukihiro UemuraEditor: Richard TrammellExpert: H. Eric Bender, M.D.Line Producer: Joseph BuscemiAssociate Producer: Paul GulyasProduction Manager: Peter BrunetteCasting Producer: Nicholas SawyerSound Mixer: Russell PurcellProduction Assistant: Davis ForgePost Production Supervisor: Christian OlguinPost Production Coordinator: Ian BryantSupervising Editor: Doug LarsenAdditional Editor: Jason MaliziaAssistant Editor: Billy Ward

Psychedelic substances have reinvigorated clinical and research interests, and have added to psychiatry’s ever-expanding therapeutic armamentarium.

Were you to google “Carl Jung and Nazism”—and I’m not suggesting that you do—you would find yourself hip-deep in the charges that Jung was an anti-Semite and a Nazi sympathizer. Many sites condemn or exonerate him; many others celebrate him as a blood and soil Aryan hero. It can be nauseatingly difficult at times to […]

Popular religions have tried to open the eyes of the deprived masses but there appears to be seemingly inexplicable appreciation of the rich by the poor and the middle-class

American Psychological Association

Baltimore, U.S.A. : Williams & Wilkins, [1921-1946]

Boston : The Old Corner Bookstore, 1906-1921.

New York, NY : Routledge, 2019.

Bad horror films usually come with an excessive reliance on jump scares; Shut In too has its fair share.

It is a useful tool that offers career clarity and opens up new possibilities.

Albany, NY : State University of New York Press, [2023]

New York, NY : Oxford University Press , 2024.

[New York] : W. W. Norton & Company, Incorporated, 2024.

Washington, DC : American Psychiatric Association Publishing, [2024]

Cheltenham, UK ; Northampton, MA : Edward Elgar Publishing, [2023]

Delhi Waveriders coach Cedric D’Souza says the league has been a fantastic platform for the development of young Indian players

The start-up wants to develop treatments based on two kinds of bacteria linked to the antiseizure effects of the ketogenic diet

The start-up wants to develop treatments based on two kinds of bacteria linked to the antiseizure effects of the ketogenic diet

Study in rats and fruit flies suggests that these drugs could inspire better, ketamine-like antidepressants

Chronic morphine treatment in mice restored a narcolepsy-related deficit in the brain, decreasing symptoms 

Education officials across the Caribbean and Latin America have asserted that teachers will be in need of psycho-social support for their return to the classroom, following the COVID-19 pandemic. Approximately 91,710 teachers and seven million...

As part of Penn State’s 2020 spring commencement activities, Lena Becker will represent the Department of Psychology as its student marshal. Becker, a Paterno Fellow and Schreyer Scholar, will graduate with a bachelor of science degree in psychology and a bachelor of arts degree in Spanish.

NPR's Michel Martin speaks with University of Texas at San Antonio professor of clinical psychology, Dr. Mary McNaughton-Cassill, about common stress responses to disasters and other traumatic events.

Psychotropic drugs seized in city

Jeholopsyche liaoningensis is a new genus and species of flying insect from northeastern China, recently revealed in two new fossil specimens.

The post Meet the 125-million-year-old pollinator “Jeholopsyche liaoningensis” appeared first on Smithsonian Insider.

Source: Streetwise Reports   04/27/2020

Avadel Pharmaceuticals Plc (AVDL:NASDAQ) today announced "positive topline data from its pivotal Phase 3 REST-ON trial assessing the safety and efficacy of FT218, an investigational, once-nightly formulation of sodium oxybate for the treatment of excessive daytime sleepiness and cataplexy in patients with narcolepsy." The firm pointed out that it met all three of the co-primary efficacy endpoints in the study for each of three dosage levels which it claims demonstrates "highly significant, clinically meaningful improvements on the Maintenance of Wakefulness Test, Clinical Global Impression-Improvement and mean weekly cataplexy attacks."

The company's Chief Medical Officer Jordan Dubow, M.D., commented, "We are excited to see these positive topline data from the REST-ON study, where all three dose levels of once-nightly FT218 demonstrated a statistically significant and clinically meaningful improvement on the measures of the two prominent symptoms of narcolepsy, as well as an improvement in overall functioning compared to placebo...Once-nightly FT218 delivered a clinically meaningful response within three weeks of treatment initiation, which was sustained through each treatment period...We think once-nightly FT218, if approved, has the potential to be a meaningful contributor to patient care."

Avadel Pharma's CEO Greg Divis remarked, "The successful outcome of the REST-ON study strengthens our belief that, if approved, once-nightly FT218 has the potential to be a significant advancement for patients in the estimated $1.7 billion twice-nightly sodium oxybate market. Our proprietary market research with physicians and patients informs us that there is a strong interest in a once-nightly sodium oxybate formulation. We look forward to sharing the results from the REST-ON study with the FDA and progressing toward a potential approval that would allow us to bring this important treatment to the patients who need it most. If approved, FT218 would be the first once-nightly therapy to address both excessive daytime sleepiness and cataplexy in patients with narcolepsy."

The REST-ON study is a double-blind, randomized, placebo-controlled Phase 3 trial to assess the efficacy and safety of once-nightly FT218, a formulation of sodium oxybate using Avadel's proprietary Micropump technology for extended-release oral suspension in the treatment of excessive daytime sleepiness and cataplexy in patients suffering from narcolepsy. The company stated that 212 patients were enrolled in the study and result "showed that the 9 g dose of once-nightly FT218 demonstrated a highly significant and clinically meaningful improvement compared to placebo across all three co-primary endpoints."

The company advised that FT218 has been granted Orphan Drug Designation from the U.S. FDA for the treatment of narcolepsy. The firm added that the designation was granted on basis that FT218 may be clinically superior to a formulation of sodium oxybate that is already approved by the FDA for the same indication.

Avadel Pharmaceuticals is biopharmaceutical company headquartered in Dublin, Ireland. The company's primary focus is on the development and potential FDA approval for FT218, which just completed its Phase 3 REST-ON clinical trial for the treatment of narcolepsy patients suffering from excessive daytime sleepiness and cataplexy. The firm also develops and markets sterile injectable drugs for use in hospital settings.

Avadel started off the day with a market capitalization of around $456.2 million with approximately 46.4 million shares outstanding and a short interest of about 14.00%. AVDL shares opened more than 34% higher today at $13.30 (+$3.37, +34.28%) over Friday's $9.83 closing price and reached a new 52-week high price this morning of $13.49. The stock has traded today between $11.90 and $13.49 per share and is currently trading at $12.27 (+$2.44 +24.82%).

Disclosure:
1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None.
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( Companies Mentioned: AVDL:NASDAQ, )

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Gendered expectations in marriage are not just bad for women, they are also bad for men, according to a new study by University of Connecticut (UConn) sociologists.

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An increasing number of US adults are using marijuana, as fewer people perceive the drug as harmful, according to a survey of over 500000 US adults conducted between 2002 and 2014 published in The Lancet Psychiatry. As marijuana has become increasingly potent over the past decade, the authors say that the findings suggest the need for improved education and prevention messages regarding the risks of marijuana.

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