Google Street View - Time Lapse Movie

Immigrants have been disproportionately hit by the global economic crisis that began in 2008 and now confront a number of challenges. The report, which has a particular focus on Germany, Ireland, Spain, the United Kingdom, and United States finds that the unemployment gap between immigrant and native workers has widened in many places.

A new imaging technique may give researchers fresh insights into brain development, function, and disease

The human brain is often said to be the most complex object in the known universe, and there’s good reason to believe that it is. That lump of jelly inside your head contains at least 80 billion nerve cells, or neurons, and even more of the non-neuronal cells called glia. Between them, they form hundreds of trillions of precise synaptic connections; but they all have moveable parts, and these connections can change. Neurons can extend and retract their delicate fibres; some types of glial cells can crawl through the brain; and neurons and glia routinely work together to create new connections and eliminate old ones.

These processes begin before we are born, and occur until we die, making the brain a highly dynamic organ that undergoes continuous change throughout life. At any given moment, many millions of them are being modified in one way or another, to reshape the brain’s circuitry in response to our daily experiences. Researchers at Yale University have now developed an imaging technique that enables them to visualise the density of synapses in the living human brain, and offers a promising new way of studying how the organ develops and functions, and also how it deteriorates in various neurological and psychiatric conditions.

Related: Brain’s immune cells hyperactive in schizophrenia

Related: 3D model of a nerve terminal in atomic detail | Mo Costandi

New research provides evidence for the idea that sleep restores cellular homeostasis in the brain and helps us to forget irrelevant information

We spend one third of our lives sleeping, but we still do not know exactly why we sleep. Recent research shows that that the brain does its housekeeping while we sleep, and clears away its waste. According to another hypothesis, sleep plays the vital role of restoring the right balance of brain synapses to enhance learning, and two studies published in today’s issue of Science now provide the most direct evidence yet for this idea.

We do know that sleep is important for consolidating newly formed memories. During waking hours, we learn all kinds of new information, both consciously and unconsciously. To store it, the brain modifies large numbers of synaptic connections, making some of them stronger and larger, and it’s now thought that as we sleep other synapses are weakened or destroyed, so that the important new information is stored for later use, while irrelevant material, which could interfere with learning, is not.

Related: The Homer Simpson effect: forgetting to remember

Related: How to optimise your brain's waste disposal system

"Happy Mother's Day to me and to all those amazing mothers out there," wrote Shilpa Shetty

"Happy Mother's Day to me and to all those amazing mothers out there," wrote Shilpa Shetty

Transfer amounts should also be linked to CPI. While PM-KISAN covers only farmers and is much more expensive and exclusive, such a transfer would avoid narrow coverage, also avoiding inclusion/exclusion errors

The colour-zoning of India (red, orange and green) and the limited relaxations with several caveats have not helped re-start economic activity.

Fourteen people were rescued from under the debris of a house that collapsed in Mumbai's Kandivali this morning.

ECLIPSEDWING exploits the SMB vulnerability patched by MS08-67. It affects Microsoft Windows 2000, 2003, and XP. Note that this exploit is part of the recent public disclosure from the "Shadow Brokers" who claim to have compromised data from a team known as the "Equation Group", however, there is no author data available in this content. Consider this exploit hostile and unverified. For research purposes only. Description has been referenced from http://medium.com/@networksecurity.

A recent decision of the Employment Appeal Tribunal has stressed that trivial acts, even if related to a protected characteristic, will not constitute unlawful harassment. The case of Henderson v GMB is a useful reminder that the Equality Act is not...

It is unclear how the corpse was driven from Lagos, through other states, to Akwa Ibom despite a ban on inter-state transportation.

The post Coronavirus: Akwa Ibom seizes corpse ‘smuggled’ into state from Lagos appeared first on Premium Times Nigeria.

If the ‘Bill on Protection against Infectious Diseases 2020’ presently in the Senate is signed into law, anyone found transporting a corpse of someone who died of infectious disease would pay a fine of N2 million.

The post Senate bill proposes N2m fine for transporting corpse without permit appeared first on Vanguard News.

The Ogun State Ministry of Health has reacted to a viral video circulating in the social media about a corpse claimed to be a victim of COVID-19 at its Primary Health Center (PHC), Oke-Ilewo, Abeokuta on Friday, May 9, 2020. The Hon. Commissioner for Health, Ogun State, Dr. Tomi Coker, in a statement said that the
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The post Ogun Ministry of Health reacts to viral video of corpse claimed to be COVID-19 victim at its PHC appeared first on Vanguard News.

[This Day] Akure -The Ondo State Government yesterday asked all residents that have deceased relations in all government mortuaries in the state to claim and burry them within one month or it would conduct mass burial for the corpses after the ultimatum.

Justin Gaethje put on a striking masterclass to score a surprise knockout victory over Tony Ferguson and win the interim lightweight title at UFC 249, which took place at the VyStar Veterans Memorial Arena in Jacksonville, Florida on Saturday.

https://www.youtube.com/watch?v=3nJVrgVSc0w

К вопросу, почему плоды сверх острых перцев стоят дорого. Гражданин записал видео роста перца Trinidad Moruga Scorpion. На весь процесс от посадки до сбора урожая ушло 8 месяцев. И это при благоприятных условиях, температура, свет.

Написал ammugammU на scoville.d3.ru / комментировать

Actor Taapsee Pannu put out yet another throwback picture from her archives on Saturday, and shared her childhood experience, noting how the school does play an important part in shaping one's personality. The 32-year-old actor posted a photo on Instagram with her school principal in an auditorium with kids.

The Thappad actress told that she went to meet her school principal and was surprised to meet inquisitive kids.

 

 

 

View this post on Instagram

I was visiting Jaipur for an event and I remembered that my school (ex)vice principal is now Principal in a school of Jaipur. Couldn’t miss this opportunity to meet her. What was unexpected was that her entire school came to meet and kids were really sweet and inquisitive about a lot of things. School does play an important part in shaping up your personality and your teachers are the ‘karigars’ moulding the raw stones we all are. I don’t know if it’s because I’ve been a nerdy kid or coz I’m grateful to my teachers for letting me shape up all aspects of my personality equally, that I keep going back to my childhood time n again. #Throwback #Archive #QuarantinePost

A post shared by Taapsee Pannu (@taapsee) onMay 9, 2020 at 12:22am PDT

Pannu wrote, "I was visiting Jaipur for an event and I remembered that my school (ex)vice-principal is now Principal in a school of Jaipur. Couldn't miss this opportunity to meet her. What was unexpected was that her entire school came to meet and kids were really sweet and inquisitive about a lot of things."

While talking about the visitor experience, the 'Naam Shabana' star pointed out the important role played by teachers in shaping one's personality. The actor also revealed she's been a 'nerdy' in school, and she keeps going back to her school time and again. "School does play an important part in shaping up your personality and your teachers are the 'karigars' moulding the raw stones we all are. I don't know if it's because I've been a nerdy kid or coz I'm grateful to my teachers for letting me shape up all aspects of my personality equally, that I keep going back to my childhood time n again," she added.

The post on the photo-sharing platform garnered more than 1 lakh likes from fans and celebrity followers including Kajal Aggarwal.

Last week, the 'Manmarziyaan' actor shared her picture where she is seen caught in a moment while using a VR headset. In the post, she spoke of how technology can take us over.

Lately, the 'Thappad' star has been sharing many throwback pictures as she earlier announced on Instagram that she will be posting a series to refresh some memories during the coronavirus lockdown. Taapsee is currently at home like many other celebrities as the country is under lockdown to prevent the spread of the coronavirus.

Catch up on all the latest entertainment news and gossip here. Also, download the new mid-day Android and iOS apps.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

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The National Disaster Response Force (NDRF) on Sunday informed that few people were feared to be trapped under the debris after a wall of a house collapsed in Kandivali (West) area of Mumbai. According to NDRF, so far three people have been rescued.

"Four to five people possibly trapped after wall of a house collapsed in Kandivali (West) area of Mumbai. 3 people rescued till now," the NDRF said.

A rescue operation is underway at the mishap site.

Catch up on all the latest Mumbai news, crime news, current affairs, and a complete guide from food to things to do and events across Mumbai. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

After the success of song 'Pyar Karona', Salman Khan has shared the teaser of his new song 'Tera Bina' with Jacqueline Fernandez.

Virgin Australia has complained to the competition regulator about Qantas chief executive Alan Joyce's suggestion it would be unfair for the government to prop up one airline.

An aviation insider fears the demise of Virgin Australia would give Qantas a licence to charge $1,000 for a Sydney to Melbourne airfare. Velocity Frequent Flyer points are also at risk.

माननीय अध्यक्ष: श्री ए.राजा जी ।

राजा जी का दूसरा विषय है ।

SHRI A. RAJA (NILGIRIS): Sir, a tragic incident happened in the early hours of Monday, the 2nd December 2019 at Nadoor Village near Mettupalayam Municipality in my constituency. A compound wall constructed by  a private individual had collapsed,  instantly killing 17 Scheduled Castes people, including children. The fact remains that the villagers had on several occasions complained to the district administration and the State Government with regard to the danger posed by the compound wall. The incident led to scores of people, including relatives of the deceased and the members of the pro-Dalit organisations like Tamil Tigers and other political parties protest against the district administration and pressing for reasonable demand to accommodate them inside the Mettupalayam Government Hospital Campus.

Three persons were rescued after the wall of a house in northern Mumbai suburb Kandivali collapsed on Sunday morning, an official said. Four to five people are possibly trapped after the wall of the house behind Sabria Masjid in Dalji Pada area collapsed and rescue operation is underway, a National Disaster Response Force (NDRF) official said.

Fourteen people were rescued after the wall of a house collapsed in suburban Kandivali on Sunday morning, an official said. Two of those rescued received minor injuries and were admitted to a hospital, he said. The wall of the ground-plus-two-floor structure, known as Dipjyoti chawl, located in Lalji Pada area collapsed early morning, an official at the disaster control room said. Some locals said the incident took place when residents were asleep and they were unable to come out. Seven persons stranded on the upper floors were rescued after firefighters cut the grill and brought them down with the help of a ladder, the official said, adding that total 14 people brought out to safety from the structure. Four fire engines, a rescue van and an ambulance were pressed into service. Two persons, aged 45 and 48, received minor injuries and were admitted to Oscar Hospital, he said. Rescue operation was still underway at the site, he said.

Calls for the renewal of hundreds of thousands of lapsed insurance policies have begun, reports P Sainath.

Ferguson, who came into the fight on a 12-win streak, suffered damage as Gaethje chopped at his legs and landed thunderous hooks before referee Herb Dean stepped in to end the fight late in the fifth round.

Three persons, including the owner of the well, died and two others were injured, after the mound of earth collapsed on them while they were repairing the old well at Kodoli village of Panhala taluka in Kolhapur district on Saturday night.

Fire tenders were dispatched to the spot along with an NDRF team and rescue operations are underway.

Vivo's sub-brand iQOO has been making a name for itself with a couple of flagship devices like the iQOO Neo 3. More recently, when MediaTek announced the new Dimensity 1000+ chipset, iQOO said it would launch a smartphone with the processor.

Mohanlal, the complete actor of Malayalam Cinema and his beloved wife Suchitra Mohanlal have completed 32 years of marital bliss today. The couple had a quiet celebration for their 32nd anniversary in quarantine, as the country has been currently observing all

Kannada actors Radhika Pandit and Yash became proud parents to a baby boy in October 2019. The couple received congratulatory wishes from all their fans, but they have not shared pictures of the baby. Fans have been waiting with eagerness to

The highly awaited Darshan's Roberrt glimpse video is finally out! To mark May Day, i.e. Labour Day, the makers of the action-thriller released a video dedicating to all the off-screen warriors, who served behind the camera for the film.

Punjab Government has decided to promote students of Class 10 board exams 2020. Candidates who have appeared for the PSEB Class 10 Matric Board exams will be promoted on the basis of their pre-board examination results. Chief Minister of Punjab, Captain

Justin Gaethje put on a striking masterclass to score a surprise knockout victory over Tony Ferguson and win the interim lightweight title at UFC 249, which took place at the VyStar Veterans Memorial Arena in Jacksonville, Florida on Saturday.

Archives, Room Use Only - TK5741.T74 1902

Many people trapped after a ground-plus-two-storey chawl structure collapsed at Dipjyoti Chawl of Lalji Pada in Kandivali West early on Sunday.

Still to come to terms with the loss of their loved ones in violence in parts of northeast Delhi, relatives are anxiously waiting outside GTB hospital's mortuary for the postmortem to be conducted before the bodies are handed over to them.

Search and rescue operations are still under way, incident escalated to a Level II emergency

Further details are awaited.

The bacterial type VI secretion system (T6SS) secretes many toxic effectors to gain advantage in interbacterial competition and for eukaryotic host infection. The cognate immunity proteins of these effectors protect bacteria from their own effectors. PldB is a T6SS trans-kingdom effector in Pseudomonas aeruginosa that can infect both prokaryotic and eukaryotic cells. Three proteins, PA5086, PA5087 and PA5088, are employed to suppress the toxicity of PldB-family proteins. The structures of PA5087 and PA5088 have previously been reported, but the identification of further distinctions between these immunity proteins is needed. Here, the crystal structure of PA5086 is reported at 1.90 Å resolution. A structural comparison of the three PldB immunity proteins showed vast divergences in their electrostatic potential surfaces. This interesting phenomenon provides an explanation of the stockpiling mechanism of T6SS immunity proteins.

Factor for inversion stimulation (Fis) is a versatile bacterial nucleoid-associated protein that can directly bind and bend DNA to influence DNA topology. It also plays crucial roles in regulating bacterial virulence factors and in optimizing bacterial adaptation to various environments. Fis from Pseudomonas aeruginosa (PA4853, referred to as PaFis) has recently been found to be required for virulence by regulating the expression of type III secretion system (T3SS) genes. PaFis can specifically bind to the promoter region of exsA, which functions as a T3SS master regulator, to regulate its expression and plays an essential role in transcription elongation from exsB to exsA. Here, the crystal structure of PaFis, which is composed of a four-helix bundle and forms a homodimer, is reported. PaFis shows remarkable structural similarities to the well studied Escherichia coli Fis (EcFis), including an N-terminal flexible loop and a C-terminal helix–turn–helix (HTH) motif. However, the critical residues for Hin-catalyzed DNA inversion in the N-terminal loop of EcFis are not conserved in PaFis and further studies are required to investigate its exact role. A gel-electrophoresis mobility-shift assay showed that PaFis can efficiently bind to the promoter region of exsA. Structure-based mutagenesis revealed that several conserved basic residues in the HTH motif play essential roles in DNA binding. These structural and biochemical studies may help in understanding the role of PaFis in the regulation of T3SS expression and in virulence.

A new pseudopolymorph of dodeca­chloro­penta­silane, namely a benzene monosolvate, Si5Cl12·C6H6, is described. There are two half mol­ecules of each kind in the asymmetric unit. Both Si5Cl12 mol­ecules are completed by crystallographic twofold symmetry. One of the benzene mol­ecules is located on a twofold rotation axis with two C—H groups located on this rotation axis. The second benzene mol­ecule has all atoms on a general position: it is disordered over two equally occupied orientations. No directional inter­actions beyond normal van der Waals contacts occur in the crystal.

The crystal structure of Pseudomonas aeruginosa Fis is composed of an N-terminal flexible loop and a C-terminal helix–turn–helix motif.