Meropenem/vaborbactam resistance in Klebsiella pneumoniae is associated with loss of function mutations in the OmpK35 and OmpK36 porins. Here we identify two previously unknown loss of function mutations that confer cefuroxime resistance in K. pneumoniae. The proteins lost were NlpD and KvrA; the latter is a transcriptional repressor controlling capsule production. We demonstrate that KvrA loss reduces OmpK35 and OmpK36 porin production, which confers reduced susceptibility to meropenem/vaborbactam in a KPC-3 producing K. pneumoniae isolate.

Türkiye devleti ile uluslararası alanda terör örgütü olarak kabul edilen PKK arasındaki çözüm sürecinin çökmesi, Temmuz 2015’te çatışmaların yeniden başlaması ve daha sonra derinleşen şiddet sarmalı, yeni bir çözüm sürecinin inşasını hiç olmadığı kadar gerekli kılıyor.

Ujjwal Chaudhry, director, RedSeer Consulting, says, “Metro consumers buy more branded products, but the same value proposition would not be as attractive to a tier II consumer.”

iPhone SE (2020) was unveiled last month, and this "affordable" new offering from Apple is priced in India starting at Rs. 42,500. India availability and sale details were not announced at the...

If you notice, pumpkin has several appetising sweet and savoury dishes in the western countries in form of salad, soup and pies. Keeping this in mind, we bring you a recipe that will make the simple...

NEW CASTLE (July 24, 2018) – Following a 14-month review of Delaware’s opioid use disorder treatment system, a research team from the Johns Hopkins Bloomberg School of Public Health and the Bloomberg American Health Initiative today recommended four major strategies to achieve the state’s goal of a system of care that is accessible, evidence-based, individualized, […]

OnePlus Bullets Wireless Z price in India is Rs 1,999 and the product will be available in three options, black, blue and oat.

The details may be technical, but the concepts are clear when it comes to analyzing seasonal retail data

A member of the holy trinity, that also included Chuni Goswami and Tulsidas Balaram, Banerjee was the last surviving scorer of the 1962 Asiad gold-winning team.

After the Government extended the lockdown to curb the spread of COVID-19 outbreak, the Ministry of Home Affairs (MHA) released a set of revised guidelines for services that are allowed during the lockdown. Several ecommerce companies including Flipkart, Snapdeal and Paytm Mall are all set to resume full operations from April 20. Read to find […]

The post Flipkart, Amazon, Paytm Mall, Snapdeal All Set To Sell Non-Essential Items From April 20th first appeared on Trak.in . Trak.in Mobile Apps: Android | iOS.

1 Seychellois Rupee = 9.2992 Pakistani Rupee

1 Trinidad and Tobago Dollar = 23.6254 Pakistani Rupee

1 Swedish Krona = 16.3377 Pakistani Rupee

Winds are from the Northwest at 16.1 gusting to 21.9 MPH (14 gusting to 19 KT). The pressure is 1012.7 mb and the humidity is 59%. The wind chill is 24. Last Updated on May 9 2020, 11:56 am EDT.

1 Slovak Koruna = 7.1895 Pakistani Rupee

1 Serbian Dinar = 1.472 Pakistani Rupee

1 Polish Zloty = 37.969 Pakistani Rupee

1 Qatari Rial = 43.8474 Pakistani Rupee

1 Indian Rupee = 2.1145 Pakistani Rupee

1 Pakistani Rupee = 7.4538 Iraqi Dinar

1 Pakistani Rupee = 32.5055 Zambian Kwacha

1 Pakistani Rupee = 0.1149 South African Rand

1 Pakistani Rupee = 1.5683 Yemeni Rial

1 Pakistani Rupee = 3.7895 CFA Franc BCEAO

1 Pakistani Rupee = 146.5738 Vietnamese Dong

1 Pakistani Rupee = 0.0626 Venezuelan Bolivar Fuerte

1 Pakistani Rupee = 63.3198 Uzbekistan Som

1 Pakistani Rupee = 0.2702 Uruguayan Peso

1 Pakistani Rupee = 0.0063 US Dollar

1 Pakistani Rupee = 23.8041 Ugandan Shilling

1 Pakistani Rupee = 0.1681 Ukrainian Hryvnia

1 Pakistani Rupee = 14.4955 Tanzanian Shilling

1 Pakistani Rupee = 0.187 New Taiwan Dollar

1 Pakistani Rupee = 0.0423 Trinidad and Tobago Dollar

1 Pakistani Rupee = 0.0444 Turkish Lira

1 Pakistani Rupee = 0.0182 Tunisian Dinar

1 Pakistani Rupee = 0.2006 Thai Baht

1 Pakistani Rupee = 0.0548 Salvadoran Colon

1 Pakistani Rupee = 61.7601 Sierra Leonean Leone

1 Pakistani Rupee = 0.1391 Slovak Koruna

1 Pakistani Rupee = 0.0088 Singapore Dollar

1 Pakistani Rupee = 0.0612 Swedish Krona

1 Pakistani Rupee = 0.1075 Seychellois Rupee

1 Pakistani Rupee = 0.0235 Saudi Riyal

1 Pakistani Rupee = 0.4598 Russian Ruble