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Breast Cancer Drug Might Help Men on Prostate Cancer Therapy

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Breast Cancer Drug Might Help Men on Prostate Cancer Therapy
Category: Health News
Created: 8/28/2012 10:05:00 AM
Last Editorial Review: 8/28/2012 12:00:00 AM


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Daily Aspirin May Help Fight Prostate Cancer, But Not Breast Cancer

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Daily Aspirin May Help Fight Prostate Cancer, But Not Breast Cancer
Category: Health News
Created: 8/27/2012 6:05:00 PM
Last Editorial Review: 8/28/2012 12:00:00 AM


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Race May Affect Quality of Prostate Cancer Surgical Care

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Race May Affect Quality of Prostate Cancer Surgical Care
Category: Health News
Created: 8/28/2012 6:05:00 PM
Last Editorial Review: 8/29/2012 12:00:00 AM


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Afinitor Disperz Approved for Rare Pediatric Cancer

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Afinitor Disperz Approved for Rare Pediatric Cancer
Category: Health News
Created: 8/29/2012 6:05:00 PM
Last Editorial Review: 8/30/2012 12:00:00 AM


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Breast Cancer Drug May Harm the Heart More Than Thought

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Breast Cancer Drug May Harm the Heart More Than Thought
Category: Health News
Created: 8/30/2012 6:05:00 PM
Last Editorial Review: 8/31/2012 12:00:00 AM


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Too Few Girls Get HPV Vaccine Against Cancer: CDC

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Too Few Girls Get HPV Vaccine Against Cancer: CDC
Category: Health News
Created: 8/30/2012 4:05:00 PM
Last Editorial Review: 8/31/2012 12:00:00 AM


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New Hope for Early Detection of Ovarian Cancer

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: New Hope for Early Detection of Ovarian Cancer
Category: Health News
Created: 8/26/2013 9:35:00 AM
Last Editorial Review: 8/26/2013 12:00:00 AM


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Could Heavy Coffee Drinking Help Men Battle Prostate Cancer?

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Could Heavy Coffee Drinking Help Men Battle Prostate Cancer?
Category: Health News
Created: 8/26/2013 7:36:00 PM
Last Editorial Review: 8/27/2013 12:00:00 AM


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Terms Docs Use Can Influence Patients' Cancer Choices

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Terms Docs Use Can Influence Patients' Cancer Choices
Category: Health News
Created: 8/26/2013 4:36:00 PM
Last Editorial Review: 8/27/2013 12:00:00 AM


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Hodgkin Lymphoma Treatment Tied to Higher Risk of Stomach Cancer in Study

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Hodgkin Lymphoma Treatment Tied to Higher Risk of Stomach Cancer in Study
Category: Health News
Created: 8/28/2013 9:35:00 AM
Last Editorial Review: 8/28/2013 12:00:00 AM


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Drinking Before First Pregnancy Raises Risk of Breast Cancer: Study

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Drinking Before First Pregnancy Raises Risk of Breast Cancer: Study
Category: Health News
Created: 8/28/2013 4:35:00 PM
Last Editorial Review: 8/29/2013 12:00:00 AM


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Polyp Removal Doesn't Always Signal Raised Colon Cancer Risk, Study Says

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Polyp Removal Doesn't Always Signal Raised Colon Cancer Risk, Study Says
Category: Health News
Created: 8/27/2014 5:36:00 PM
Last Editorial Review: 8/28/2014 12:00:00 AM


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Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says
Category: Health News
Created: 8/27/2014 4:35:00 PM
Last Editorial Review: 8/28/2014 12:00:00 AM


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Low-Dose Aspirin, Other Painkillers May Lower Colon Cancer Risk

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Low-Dose Aspirin, Other Painkillers May Lower Colon Cancer Risk
Category: Health News
Created: 8/24/2015 12:00:00 AM
Last Editorial Review: 8/25/2015 12:00:00 AM


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Blood Pressure Drugs Linked to Longer Ovarian Cancer Survival

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Blood Pressure Drugs Linked to Longer Ovarian Cancer Survival
Category: Health News
Created: 8/24/2015 12:00:00 AM
Last Editorial Review: 8/25/2015 12:00:00 AM


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Acupuncture Best for Hot Flashes in Breast Cancer Survivors: Study

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Acupuncture Best for Hot Flashes in Breast Cancer Survivors: Study
Category: Health News
Created: 8/25/2015 12:00:00 AM
Last Editorial Review: 8/26/2015 12:00:00 AM


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Experimental Drug for Blood Cancer Shows Promise

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Experimental Drug for Blood Cancer Shows Promise
Category: Health News
Created: 8/26/2015 12:00:00 AM
Last Editorial Review: 8/27/2015 12:00:00 AM


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Childhood Cancer Survivors Who've Had One Stroke at Risk of Second

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Childhood Cancer Survivors Who've Had One Stroke at Risk of Second
Category: Health News
Created: 8/26/2015 12:00:00 AM
Last Editorial Review: 8/27/2015 12:00:00 AM


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Blood Test May One Day Predict Breast Cancer Relapse

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Blood Test May One Day Predict Breast Cancer Relapse
Category: Health News
Created: 8/26/2015 12:00:00 AM
Last Editorial Review: 8/27/2015 12:00:00 AM


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Black Women at Raised Risk of Carrying Breast Cancer Genes

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Black Women at Raised Risk of Carrying Breast Cancer Genes
Category: Health News
Created: 8/27/2015 12:00:00 AM
Last Editorial Review: 8/28/2015 12:00:00 AM


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Longer Colonoscopy Time May Cut Cancer Risk

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Longer Colonoscopy Time May Cut Cancer Risk
Category: Health News
Created: 8/27/2015 12:00:00 AM
Last Editorial Review: 8/28/2015 12:00:00 AM


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Fewer Cancer-Causing Chemicals in E-Cigs Than Regular Cigarettes: Study

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Fewer Cancer-Causing Chemicals in E-Cigs Than Regular Cigarettes: Study
Category: Health News
Created: 8/19/2016 12:00:00 AM
Last Editorial Review: 8/22/2016 12:00:00 AM


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Use of Cancer-Linked Fibroid Device Declines After FDA Warning

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Use of Cancer-Linked Fibroid Device Declines After FDA Warning
Category: Health News
Created: 8/23/2016 12:00:00 AM
Last Editorial Review: 8/24/2016 12:00:00 AM


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Excess Weight Tied to Higher Risk for Many Cancers, Experts Say

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Excess Weight Tied to Higher Risk for Many Cancers, Experts Say
Category: Health News
Created: 8/24/2016 12:00:00 AM
Last Editorial Review: 8/25/2016 12:00:00 AM


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Cancer on Course to Become Top Killer of Americans

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Cancer on Course to Become Top Killer of Americans
Category: Health News
Created: 8/24/2016 12:00:00 AM
Last Editorial Review: 8/25/2016 12:00:00 AM


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Hopes Dashed for Rare Bone Cancer Treatment

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Hopes Dashed for Rare Bone Cancer Treatment
Category: Health News
Created: 8/26/2016 12:00:00 AM
Last Editorial Review: 8/26/2016 12:00:00 AM


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Common Treatment for Early Prostate Cancer May Carry Heart Risk

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Common Treatment for Early Prostate Cancer May Carry Heart Risk
Category: Health News
Created: 8/25/2017 12:00:00 AM
Last Editorial Review: 8/28/2017 12:00:00 AM


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Science Weighs in On How Fat Raises Cancer Risk

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Science Weighs in On How Fat Raises Cancer Risk
Category: Health News
Created: 9/1/2017 12:00:00 AM
Last Editorial Review: 9/1/2017 12:00:00 AM


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Bills Mount for Breast Cancer Survivors

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Bills Mount for Breast Cancer Survivors
Category: Health News
Created: 8/24/2018 12:00:00 AM
Last Editorial Review: 8/27/2018 12:00:00 AM


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Health Tip: Talking About Your Cancer Diagnosis

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Health Tip: Talking About Your Cancer Diagnosis
Category: Health News
Created: 8/28/2018 12:00:00 AM
Last Editorial Review: 8/28/2018 12:00:00 AM


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Is Teen Drinking Tied to Aggressive Prostate Cancer Later in Life?

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Is Teen Drinking Tied to Aggressive Prostate Cancer Later in Life?
Category: Health News
Created: 8/29/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM


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Justice Ruth Bader Ginsburg Treated for Pancreatic Cancer

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Justice Ruth Bader Ginsburg Treated for Pancreatic Cancer
Category: Health News
Created: 8/23/2019 12:00:00 AM
Last Editorial Review: 8/26/2019 12:00:00 AM


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Childhood Cancer Survivors Struggle With Heart Troubles

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Childhood Cancer Survivors Struggle With Heart Troubles
Category: Health News
Created: 8/26/2019 12:00:00 AM
Last Editorial Review: 8/27/2019 12:00:00 AM


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Men Should be Included in Breast Cancer Clinical Trials: FDA

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Men Should be Included in Breast Cancer Clinical Trials: FDA
Category: Health News
Created: 8/26/2019 12:00:00 AM
Last Editorial Review: 8/27/2019 12:00:00 AM


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Exercise Is Good Medicine for Advanced Colon Cancer

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Exercise Is Good Medicine for Advanced Colon Cancer
Category: Health News
Created: 8/28/2019 12:00:00 AM
Last Editorial Review: 8/28/2019 12:00:00 AM


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Can Breast Cancer Be a Risk Factor for Opioid Use Among Older Patients?

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Can Breast Cancer Be a Risk Factor for Opioid Use Among Older Patients?
Category: Health News
Created: 8/27/2019 12:00:00 AM
Last Editorial Review: 8/28/2019 12:00:00 AM


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Many Thyroid Cancer Ultrasound Scans Unnecessary

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Many Thyroid Cancer Ultrasound Scans Unnecessary
Category: Health News
Created: 8/25/2020 12:00:00 AM
Last Editorial Review: 8/26/2020 12:00:00 AM


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Cancer Radiation Can Safely Proceed During COVID-19 Pandemic: Study

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Cancer Radiation Can Safely Proceed During COVID-19 Pandemic: Study
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM


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Spotting the Signs of Deadly Melanoma Skin Cancers

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Spotting the Signs of Deadly Melanoma Skin Cancers
Category: Health News
Created: 8/22/2021 12:00:00 AM
Last Editorial Review: 8/23/2021 12:00:00 AM


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Exercise Could Help Fight 'Chemo Brain' in Breast Cancer Patients

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Exercise Could Help Fight 'Chemo Brain' in Breast Cancer Patients
Category: Health News
Created: 8/25/2021 12:00:00 AM
Last Editorial Review: 8/25/2021 12:00:00 AM


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Enlarged Prostate Doesn't Raise a Man's Odds for Cancer: Study

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Enlarged Prostate Doesn't Raise a Man's Odds for Cancer: Study
Category: Health News
Created: 8/25/2021 12:00:00 AM
Last Editorial Review: 8/25/2021 12:00:00 AM


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Cases of Advanced Cervical Cancer Keep Rising Among U.S. Women

By www.medicinenet.com
Published On :: Mon, 29 Aug 2022 00:00:00 PDT

Title: Cases of Advanced Cervical Cancer Keep Rising Among U.S. Women
Category: Health News
Created: 8/19/2022 12:00:00 AM
Last Editorial Review: 8/22/2022 12:00:00 AM


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Blood Protein Might Predict Future Diabetes, Cancer Risk

By www.medicinenet.com
Published On :: Fri, 5 Aug 2022 00:00:00 PDT

Title: Blood Protein Might Predict Future Diabetes, Cancer Risk
Category: Health News
Created: 8/5/2022 12:00:00 AM
Last Editorial Review: 8/5/2022 12:00:00 AM


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What Are the 5 Warning Signs of Bladder Cancer?

By www.medicinenet.com
Published On :: Wed, 8 Jun 2022 00:00:00 PDT

Title: What Are the 5 Warning Signs of Bladder Cancer?
Category: Diseases and Conditions
Created: 4/22/2021 12:00:00 AM
Last Editorial Review: 6/8/2022 12:00:00 AM


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New Approach Cuts Odds for Anal Cancer in People With HIV

By www.medicinenet.com
Published On :: Thu, 16 Jun 2022 00:00:00 PDT

Title: New Approach Cuts Odds for Anal Cancer in People With HIV
Category: Health News
Created: 6/16/2022 12:00:00 AM
Last Editorial Review: 6/16/2022 12:00:00 AM


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How to Manage Menopause Symptoms After Breast Cancer

By www.medicinenet.com
Published On :: Thu, 7 Jul 2022 00:00:00 PDT

Title: How to Manage Menopause Symptoms After Breast Cancer
Category: Diseases and Conditions
Created: 7/7/2022 12:00:00 AM
Last Editorial Review: 7/7/2022 12:00:00 AM


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Chromatin interaction maps identify oncogenic targets of enhancer duplications in cancer [RESEARCH]

By genome.cshlp.org
Published On :: 2024-10-29T06:46:07-07:00

As a major type of structural variants, tandem duplication plays a critical role in tumorigenesis by increasing oncogene dosage. Recent work has revealed that noncoding enhancers are also affected by duplications leading to the activation of oncogenes that are inside or outside of the duplicated regions. However, the prevalence of enhancer duplication and the identity of their target genes remains largely unknown in the cancer genome. Here, by analyzing whole-genome sequencing data in a non-gene-centric manner, we identify 881 duplication hotspots in 13 major cancer types, most of which do not contain protein-coding genes. We show that the hotspots are enriched with distal enhancer elements and are highly lineage-specific. We develop a HiChIP-based methodology that navigates enhancer–promoter contact maps to prioritize the target genes for the duplication hotspots harboring enhancer elements. The methodology identifies many novel enhancer duplication events activating oncogenes such as ESR1, FOXA1, GATA3, GATA6, TP63, and VEGFA, as well as potentially novel oncogenes such as GRHL2, IRF2BP2, and CREB3L1. In particular, we identify a duplication hotspot on Chromosome 10p15 harboring a cluster of enhancers, which skips over two genes, through a long-range chromatin interaction, to activate an oncogenic isoform of the NET1 gene to promote migration of gastric cancer cells. Focusing on tandem duplications, our study substantially extends the catalog of noncoding driver alterations in multiple cancer types, revealing attractive targets for functional characterization and therapeutic intervention.


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Colorectal Cancer Screening: A Multicomponent Intervention to Increase Uptake in Patients Aged 45-49

By www.jabfm.org
Published On :: 2024-10-25T09:26:14-07:00

Purpose:

Colorectal cancer (CRC) screening is recommended starting at age 45, but there has been little research on strategies to promote screening among patients younger than 50. This study assessed the effect of a multicomponent intervention on screening completion in this age group.

Methods:

The intervention consisted of outreach to patients aged 45 to 49 (n = 3,873) via mailed fecal immunochemical test (FIT) (sent to 46%), text (84%), e-mail (53%), and the extension to this age group of an existing standing order protocol allowing primary care nurses and medical assistants to order FIT at primary care clinics in an urban safety-net system. We used segmented linear regression to assess changes in CRC screening completion trends. Patients aged 51 to 55 were included as a comparison group (n = 3,943). Data were extracted from the EHR.

 Results:

The percentage of patients aged 45 to 49 who were up-to-date with CRC screening (colonoscopy in 10 years or FIT in last year) increased an average of 0.4% (95% CI 0.3, 0.6)) every 30 days before intervention rollout and 2.8% (95% CI 2.5, 3.1) after (slope difference 2.3% [95% CI 2.0, 2.7]). This difference persisted after accounting for small changes in the outcome observed in the comparison group (slope difference 1.7% [95% CI 1.2, 2.2]).

 Conclusions:

These results suggest that the intervention increased CRC screening completion among patients 45 to 49. Health care systems seeking to improve CRC screening participation among patients aged 45 to 49 should consider implementing similar interventions.


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Harnessing brain-body communication to understand cancer [Special Section: Symposium Outlook]

By genesdev.cshlp.org
Published On :: 2024-10-16T07:18:56-07:00

Solid tumors that arise in the body interact with neurons, which influences cancer progression and treatment response. Here, we discuss key questions in the field, including defining the nature of interactions between tumors and neural circuits and defining how neural signals shape the tumor microenvironment. This information will allow us to optimally target neural signaling to improve outcomes for cancer patients.


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Bridging brain and body in cancer [Special Section: Symposium Outlook]

By genesdev.cshlp.org
Published On :: 2024-10-16T07:18:56-07:00

Recent work has highlighted the central role the brain–body axis plays in not only maintaining organismal homeostasis but also coordinating the body's response to immune and inflammatory insults. Here, we discuss how science is poised to address the many ways that our brain is directly involved with disease. In particular, we feel that combining cutting-edge tools in neuroscience with translationally relevant models of cancer will be critical to understanding how the brain and tumors communicate and modulate each other's behavior.


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