Options for cancer detection and treatment were few in the 18th century. Medical Historian Sharon Cotner lays out some of the common practices in this week’s show.

The pair hopes to stimulate the immune system to tackle tumors bearing mutant KRas proteins, one of cancer’s toughest targets

Key enzymes in complex biosynthesis could enable alkaloid production

CAR T-cell therapy works wonders for some cancer patients. For others, it is a death sentence. To make the revolutionary therapy work for more people, scientists must devise better ways to control it

With $40 million series A funding, the start-up will develop inhibitors of proteins that make chemical modifications to RNA

Flush with another $300 million, Grail plans to enroll 135,000 people in studies this year to detect circulating tumor-derived DNA

A new report from the Cancer Research Institute highlights the U.S. and China as cell therapy leaders

With so many ingredients on hand, can the oncology community figure out how to sensibly and efficiently combine checkpoint inhibitors with other drugs?

The drug company is partnering with Calibr to develop universal CAR T-cells directed to different tumors via antibody switches

Study shows how stopping one enzyme could help drugs treat an important class of cancers more effectively

News reports linking the gene-editing technology to cancer are the latest in a series of hyped alarms due to be tested in humans soon

The drug company is partnering with Calibr to develop universal CAR T cells directed to different tumors via antibody switches

Some coauthors dissent from withdrawal of report, for which key findings have been independently confirmed

Some coauthors dissent from withdrawal of report, for which key findings have been independently confirmed

Recent work might have implications for drug development