Many children with blunt head trauma and isolated skull fractures are admitted to the hospital. Several small studies suggest that children with simple isolated skull fractures are at very low risk of clinical deterioration.

In this large cohort of children with isolated linear skull fractures after minor blunt head trauma, none developed significant intracranial hemorrhages resulting in neurosurgical interventions. These children may be considered for emergency department discharge if neurologically normal. (Read the full article)

A previous multivariable statistical model, using individual patient data, estimated the probability of abusive head trauma based on the presence or absence of 6 clinical features: rib fracture, long-bone fracture, apnea, seizures, retinal hemorrhage, and head or neck bruising.

The model performed well in this validation, with a sensitivity of 72.3%, specificity of 85.7%, and area under the curve of 0.88. In children <3 years old with intracranial injury plus ≥3 features, the estimated probability of abuse is >81.5%. (Read the full article)

Attention is a prerequisite for neurocognitive and behavioral functioning, having a crucial role in academic and social child development. Children with traumatic brain injury have pronounced deficits in attention, but the nature and consequences of these deficits remain unclear.

Lapses of attention represent a core attention deficit after pediatric mild traumatic brain injury with risk factors for complicated traumatic brain injury, or moderate/severe traumatic brain injury. Importantly, lapses of attention explain the relation between intelligence and parent-rated attention problems. (Read the full article)

Timed tests and "drill-and-kill" approaches to math education can leave students with long-lasting anxiety, writes researcher Jennifer Ruef. There's a better way to teach the subject.

QPX7728 is an ultra-broad-spectrum boronic acid beta-lactamase inhibitor that demonstrates inhibition of key serine and metallo beta-lactamases at a nano molar range in biochemical assays with purified enzymes. The broad-spectrum inhibitory activity of QPX7728 observed in biochemical experiments translates into enhancement of the potency of many beta-lactams against strains of target pathogens producing beta-lactamases. The impact of bacterial efflux and permeability on inhibitory potency were determined using isogenic panels of KPC-3 producing isogenic strains of K. pneumoniae and P. aeruginosa and OXA-23-producing strains of A. baumannii with various combinations of efflux and porin mutations. QPX7728 was minimally affected by multi-drug resistance efflux pumps in either Enterobacteriaceae, or in non-fermenters such as P. aeruginosa or A. baumannii. In P. aeruginosa, the potency of QPX7728 was further enhanced when the outer membrane is permeabilized. The potency of QPX7728 in P. aeruginosa is not affected by inactivation of the carbapenem porin OprD. While changes in OmpK36 (but not OmpK35) reduced the potency of QPX7728 (8-16-fold), QPX7728 (4 μg/ml) nevertheless completely reversed KPC-mediated meropenem resistance in strains with porin mutations, consistent with a lesser effect of these mutations on the potency of QPX7728 compared to other agents. The ultra-broad-spectrum beta-lactamase inhibition profile combined with enhancement of the activity of multiple beta-lactam antibiotics with varying sensitivity to the intrinsic resistance mechanisms of efflux and permeability indicate QPX7728 is a useful inhibitor for use with multiple beta-lactam antibiotics.

Abusive head trauma (AHT) remains a significant cause of morbidity and mortality in the pediatric population, especially in young infants. In the past decade, advancements in research have refined medical understanding of the epidemiological, clinical, biomechanical, and pathologic factors comprising the diagnosis, thereby enhancing clinical detection of a challenging diagnostic entity. Failure to recognize AHT and respond appropriately at any step in the process, from medical diagnosis to child protection and legal decision-making, can place children at risk. The American Academy of Pediatrics revises the 2009 policy statement on AHT to incorporate the growing body of knowledge on the topic. Although this statement incorporates some of that growing body of knowledge, it is not a comprehensive exposition of the science. This statement aims to provide pediatric practitioners with general guidance on a complex subject. The Academy recommends that pediatric practitioners remain vigilant for the signs and symptoms of AHT, conduct thorough medical evaluations, consult with pediatric medical subspecialists when necessary, and embrace the challenges and need for strong advocacy on the subject.

In Partnership with Wilmington University, DHSS Begins Yearlong Initiative to Train 1,000 Staff Members in Trauma-Informed Approaches to Assessing and Meeting the Needs of Clients NEW CASTLE (March 12, 2018) – The Department of Health and Social Services is partnering with Wilmington University to train more than 1,000 frontline DHSS staff in better assessing and […]

DOVER – La División de Salud Pública de Delaware (DPH, por sus siglas en inglés) ha confirmado once casos de paperas asociados a un brote entre las personas que asistieron a dos diferentes bailes mexicanos en el condado de New Castle. Siete de los casos confirmados asistieron, o viven con personas que asistieron, al evento […]

First Lady also announces first Compassionate Champion Award winners   DOVER, Del. – At a kickoff event for Trauma Awareness Month in Delaware, First Lady Tracey Quillen Carney today announced the launch of a new, growing statewide partnership for trauma-informed care to help elevate stories of the work of leaders in trauma-informed practices and approaches across the state called Trauma Informed Delaware. The […]

The daily AUM of such funds stood at Rs 74,709.11 crore in April, compared with `80,377.59 crore in March — declining Rs 5,668.48 crore.

Criticising the Sindh government for “playing politics” over the holding of mourning religious congregations by issuing a notification to ban such congregations, the Majlis-e-Wahdat Muslimeen announced on Friday that the Yaum-e-Ali procession would be organised on Ramazan 21 after...

Title: Sex Lives Often an Overlooked Casualty of Traumatic Brain Injury
Category: Health News
Created: 4/29/2013 2:35:00 PM
Last Editorial Review: 4/30/2013 12:00:00 AM

Title: Traumatic Brain Injury Common Among Homeless Men
Category: Health News
Created: 4/30/2014 12:35:00 PM
Last Editorial Review: 5/1/2014 12:00:00 AM

Title: Traumatic Life Events May Harm Women's Hearts, Study Suggests
Category: Health News
Created: 4/29/2015 12:00:00 AM
Last Editorial Review: 4/30/2015 12:00:00 AM

Title: Blood Type May Play Role in Death Risk After Trauma
Category: Health News
Created: 5/2/2018 12:00:00 AM
Last Editorial Review: 5/2/2018 12:00:00 AM

Title: AHA News: Traumatic Childhood Increases Lifelong Risk for Heart Disease, Early Death
Category: Health News
Created: 4/28/2020 12:00:00 AM
Last Editorial Review: 4/29/2020 12:00:00 AM

BACKGROUND Trauma—emotional, physical, and psychological—is common and associated with increased risk behaviors, low rates of care engagement and viral suppression, and overall poor health outcomes for people living with HIV (PLWH). This article presents the results of 15 in-depth, semi-structured interviews with PLWH in the Southeastern United States in which participants identified a trauma and described its long-lasting impact on their lives. Participants' trauma narratives described a wide range of traumas, including childhood sexual abuse, the loss of a loved one, and their HIV diagnosis.

METHODS Systematic qualitative analysis was used to delineate beliefs about causes, symptoms, treatments, quality of life, and health implications of trauma.

RESULTS: Fifteen participants completed semi-structured interviews that lasted on average 32 minutes. Participants described a wide spectrum of personal trauma that occurred both prior and subsequent to their HIV diagnosis. The types of trauma identified included physical, sexual, and psychological abuse inflicted by intimate partners, family members, and/or strangers.

LIMITATIONS A chief limitation of this study is selection bias. Additionally, the participant selection and content of the trauma narratives might have been affected by the surrounding context of the parent study centered on HIV, aging, and psychosocial stress. It is also difficult to interpret the distinction between discrete trauma experiences and the diagnosis of HIV, leading to potential information bias.

CONCLUSION This study highlights the importance of social support in coping with trauma and the effect of trauma on health-related behaviors. It also illustrates the need for additional research on the topic of trauma and trauma-informed care for PLWH. Understanding how different types of trauma affect individuals' lives is necessary to inform recommendations to provide better care for PLWH.

Objective

De novo missense mutations in the RHOBTB2 gene have been described as causative for developmental and epileptic encephalopathy.

KBP-7072 is a novel third-generation tetracycline (aminomethylcycline) antibacterial that overcomes common efflux and ribosomal protection resistance mechanisms that cause resistance in older-generation tetracyclines. KBP-7072 completed phase 1 clinical development studies for safety, tolerability, and pharmacokinetics (ClinicalTrials.gov identifier NCT02454361) and multiple ascending doses in healthy subjects (ClinicalTrials.gov identifier NCT02654626) in December 2015. Both oral and intravenous formulations of KBP-7072 are being developed. In this study, we evaluated the in vitro activities of KBP-7072 and comparator agents by CLSI document M07 (2018) broth microdilution against 531 recent geographically diverse and/or molecularly characterized Acinetobacter baumannii-A. calcoaceticus species complex (A. baumannii) isolates from the United States, Europe, Asia-Pacific (excluding China), and Latin America. A. baumannii isolates included carbapenem-resistant, colistin-resistant, tetracycline-resistant, and extended-spectrum-β-lactamase (ESBL)- and metallo-β-lactamase (MBL)-producing isolates. Overall, KBP-7072 (MIC_50/90, 0.25/1 mg/liter) was comparable in activity to colistin (92.8%/92.8% susceptible [S] [CLSI/EUCAST]) against A. baumannii isolates, inhibiting 99.2% of isolates at ≤2 mg/liter and 97.6% of isolates at ≤1 mg/liter. KBP-7072 was equally active against A. baumannii isolates, including carbapenem-resistant, colistin-resistant, and tetracycline-resistant isolates, regardless of geographic location, and maintained activity against ESBL- and MBL-producing isolates. KBP-7072 outperformed comparator agents, including ceftazidime (40.3% S [CLSI]), gentamicin (48.2%/48.2% S [CLSI/EUCAST]), levofloxacin (39.5%/37.9% S [CLSI/EUCAST]), meropenem (42.0%/42.0% S [CLSI/EUCAST]), piperacillin-tazobactam (33.3% S [CLSI]), and all tetracycline-class comparator agents, which include doxycycline (67.3% S [CLSI]), minocycline (73.8% S [CLSI]), tetracycline (37.2% S [CLSI]), and tigecycline (79.5% inhibited by ≤2 mg/liter). The potent in vitro activity of KBP-7072 against recent geographically diverse, molecularly characterized, and drug-resistant A. baumannii isolates supports continued clinical development for the treatment of serious infections, including those caused by A. baumannii.

Background:

The success of multisite collaborative research relies on effective data collection, harmonization, and aggregation strategies. Data Coordination Centers (DCC) serve to facilitate the implementation of these strategies. The utility of a DCC can be particularly relevant for research on rare diseases where collaboration from multiple sites to amass large aggregate datasets is essential. However, approaches to building a DCC have been scarcely documented.

GREENSBURG, Pa. (AP) - On a cloudy Friday afternoon 20 years ago Tuesday, an unemployed immigration lawyer went on a killing spree. It started next door to his parents’ Mt. Lebanon home, where he killed his Jewish neighbor. He went on to shoot five more people, all ethnic or racial ...

They are among the earliest enslaved African people brought to the Americas.

Less than a third say government is doing enough to help healthcare workers

Guillaume Lemay-Thivierge n’allait pas être complètement stoppé dans son élan par le confinement. C’était une question d’équilibre mental.

Attorney General Eric Holder today announced that he has chosen Sheila L. Birnbaum to head the September 11th Victim Compensation Fund program. Birnbaum, a life-long New Yorker, has decades of experience resolving complicated litigation.

One month after assuming the position, September 11th Victim Compensa­tion Fund (VCF) Special Master Sheila L. Birnbaum today published draft regulations to govern the VCF, and asked the public to give her feedback on the proposals before victims can begin submitting claims to the fund later this year.

With the 10-year anniversary of Sept. 11, 2001, approaching, September 11th Victim Compensa¬tion Fund Special Master Sheila L. Birnbaum today announced the final rule governing the fund.

September 11th Victim Compensa¬tion Fund (VCF) Special Master Sheila L. Birnbaum today announced that the fund is officially open for claimants.

Veteran District of Columbia defense attorney Charles F. Daum, 66, of Arnold, Md., was found guilty today of one count of conspiracy to obstruct justice, three counts of obstruction of justice and two counts of subornation of perjury, announced Assistant Attorney General Lanny A. Breuer of the Justice Department’s Criminal Division; Chief Cathy L. Lanier of the Washington, D.C., Metropolitan Police Department; and James W. McJunkin, Assistant Director in Charge of the FBI’s Washington Field Office.

Veteran District of Columbia defense attorney Charles F. Daum was sentenced today to serve 63 months in prison on three counts of obstructing justice in a federal drug trafficking case.

"For more than three decades now, my colleagues and I at the United States Department of Justice have been deeply privileged to pursue justice on behalf of Jewish victims of the Holocaust and also on behalf of victims of Nazi crimes committed against other groups," said Director Rosenbaum.

Taiwan has the runs on toilet paper as prices rise.

Conoce a la familia Méndez, pionera en la transformación extrema de camiones. Texas Trocas, nueva serie de Discovery en Español. Estreno 15 de septiembre a las 10PM E/P.

Daniel Tannebaum of Oliver Wyman discusses the liability issues companies who participate in the Paycheck Protection Program face, and how the government should continue to refine the legislation.

Different Bollywood celebrities are indulging in different activities at home to spend time amid the quarantine and lockdown issued by Prime Minister Narendra Modi. Some are cleaning their homes and many are sharing their workout videos. Soha Ali Khan's daughter Inaaya Naumi Kemmu have something else in mind.

Taking to her Instagram account, actress and mother Soha shared an immensely adorable picture of Inaaya arranging book in her playroom. The toddler looked cute in her black t-shirt and pink checkered trousers. The post was captioned as, ''Booked for the week! #lockdown #stoppedcountingthedays #storytime(sic).''

 

 

 

View this post on Instagram

Booked for the week! #lockdown #stoppedcountingthedays #storytime

A post shared by Soha (@sakpataudi) onApr 21, 2020 at 12:26am PDT

If you go to her Instagram account, she has been sharing pictures and videos of her family on Instagram account. She regularly updates us about her quarantine time. Recently, she shared a picture of her husband Kunal Kemmu and Inaaya. The father-daughter duo is seen peeling pees in the image! "It's just a 'matar' of time...#lockdown...#stayhome..#twopeasinapod (sic)," Soha captioned the picture.

 

 

 

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A post shared by Soha (@sakpataudi) onApr 15, 2020 at 1:46am PDT

Before this, Soha had shared an immensely adorable picture of Inaaya who could be seen sitting with her bunch of teddy bears and captioned it- House party Day 6. She also used the hashtag- Lockdown.

 

 

 

View this post on Instagram

House party Day 6 #lockdown

A post shared by Soha (@sakpataudi) onMar 29, 2020 at 10:42pm PDT

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Girgaum Chowpatty in South Mumbai is set to undergo a major transformation. The beach will be declared Mumbai's first Clean Street Hub by the Food Safety Standards of India(FSSI) and the Food and Drugs Administration(FDA) on February 28.

The shop vendors will wear uniforms which have logos of their individual brands and swachhata ambassadors will pick up litter and educate citizens about public hygiene. The beach will also have live performances by street artists.

Mumbai Mirror quoted Vishwas Mote, assistant commissioner D ward as saying, We received FDA and FSSI guidelines from Delhi under the Swachh Bharat Abhiyan on maintaining hygiene at Bhel Plaza. We had audited the stalls in December and completed their training in January."

He also added that the trees around the stalls will have tree guards and seating arrangements will be made for people to sit and enjoy live performances on the beach.

"This is being revamped to international standards. There will more lights for the stalls. And to inculcate a sense of responsibility in keeping the stalls clean, the stall owners will hire two swachhta ambassadors. They will pick up any thrown litter, and will educate people on civic sense, to make them responsible for their own garbage."

Mote also mentioned that the Swachhata ambassadors will be given white uniforms and white caps. He said, "It is a multi-directional approach, where even helpers and chefs will sport branded uniforms for each stall, and the boards and nameplates will have a uniform design. The common hand-washing area for patrons will also be spruced up."

A vendor, Atul Gupta said that they had received training for four hours from the BMC.

He added, "We were told that if we had any vices like chewing tobacco or smoking, we should do it outside the beach, and not while serving customers. We were given minute details about washing hands and serving customers. We were instructed not just to clean the work stations, but also the inside of refrigerators. If we keep our surroundings clean, it will also keep rats and roaches at bay."

Indrani Malkani who is the member of the high-powered committee appointed by Bombay High Court said, "Hygiene is an all-encompassing aspect. Not just cooking part, but even when they are washing up. Street food is a great attraction in South East Asian countries, and Girgaum Chowpatty is synonymous with bhelpuri. The idea of inculcating hygiene habits among those who make and serve food is the prime focus."

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The article has been sourced from third-party source and Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. All information provided on this article is for informational purposes only.

Going to a new restaurant is no longer about discovering what it has to offer on arrival. An online recce of the place is now part of the eating-out ritual. So, when we spot bhutte ki kees on the menu of The Culture House in Girgaum, we know we are ordering the much-loved dish from Indore's Sarafa Bazaar to satiate our Madhya Pradeshi palate — and to employ it as a litmus test to gauge the attention the recently opened restaurant pays to the vegetarian flavours of northern and western India it promises to bring to Mumbaikars.

We head to the eatery with a friend on a crisp Wednesday night, where we are welcomed by a hospitable staff. The spacious dining area has a haveli-like feel with chandeliers and wooden engravings. Located on a slightly raised level, it even has a vintage elevator for guests; a thoughtful addition, the friend points out.

Bhutte ki kees

As planned, we call for the bhutte ki kees (Rs 279) from the starters right away. "It will be made of sweet corn, though," the server tells us. Important information, considering the original recipe features desi corn, a monsoon crop, which isn't as sweet. But we are used to this jugaad at home, too, and are keen on seeing how the chef finds his way around it. The dish arrives in quick time, but is of a runnier consistency than it should be, and the mild use of spices does little to combat the extra sweetness. Disappointed, we move on to the one-plate meals, from which we pick the khichu khau suey (Rs 379) and Delhi stuff chilla (Rs 279).

Khichyu khausuey

The chilla, or besan pancake, is a staple on winter shaadi menus up north, served sizzling hot. We like the twist of stuffing it with paneer bhurji, but in the process, the chilla seems to have stayed on the tava a tad too long. The khau suey, a Gujarati twist on the Burmese dish, is what has got us all excited. And digging into the cotton-soft rice flour balls swimming in a coconut milk and curd broth leaves us reaching for more. The fried onions, peanuts and soya sticks make for the perfect accompaniments. But we do agree with our fellow diner when she remarks that the broth could have been thicker.

From the plethora of mains, we go for green Gujarat with bhakri (Rs 449). The undhiyo-like sabzi made with fewer winter veggies tastes just fine, as does the accompanying kadhi, but there is little on the platter that justifies the steep price.

Strawberry phirni

It's time for dessert, and from the seasonal options, we pick their strawberry phirni (Rs 349), which is a regular phirni topped with slices of the fruit. The moongdal sheera (Rs 299), when had later at home, reminds us of another winter shaadi indulgence, but we have tasted better versions. We'll return another day. But only because there is still much left to be tried from the vast menu.

AT The Culture House, Soni Building, opposite Bharati Vidya Bhavan, Girgaum
Time 11 am to 11.30 pm
CALL 30151598

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Telly actor Saumya Tandon is part of a campaign to distribute reusable masks and face shields to frontline workers on the streets. The Bhabhiji Ghar Par Hai actor was spotted in Andheri distributing the kits to vegetable vendors and police personnel.

Main bhi artist

Aishwarya Sakhuja, who has taken up sketching during the lockdown, is enjoying the process. "I never thought I would be good at it, but I've surprised myself. I still have a long way to go but my friends have been loving my sketches," she adds.

Mamma mia

Jag Jaanani Maa Vaishno Devi actor Madirakshi Mundle is bonding with her mother during the lockdown. She has special plans for Mother's Day. "I plan to cook her favourite meal and refurbish an old saree to a suit with embroidery work on it."

The web game

Mere Sai actor Tushar Dalvi is set to make his digital debut on Netflix with Anurag Kashyap's Choked. He says, "Working with Anurag Kashyap is a dream come true. His films don't underplay issues."

Slambook: Parull Chaudhry

One superpower you wish to possess?
The power of illusions.

One thing you won't share?
My mom's laddoos.

Your guilty pleasure movie?
Dumb and Dumber (1994).

One thing you are guilty of?
Of unknowingly hurting my parents.

Your worst project?
Being part of an episode of supernatural show in which I played a 300-year-old witch. Wearing prosthetics was painful.

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The film revolves around a guy who is type 2 diabetic which decreases male fertility as it lowers the testosterone level. The love of Saumya and Ganesh is as beautiful and pristine as the flowers on trees. Problem is that they don’t know how to do it as their ‘natural bond of friendship’ conceals, sheathes, envelopes deeper feelings that are still raw or dormant. This is how Saumya and Ganesh’s love story begins.  The admission of love comes finally, though indirectly when she thinks he is talking about some other girl whereas actually he is proposing marriage to her. The story has no villain