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Boronic ester-templated pre-rotaxanes as versatile intermediates for rotaxane endo-functionalisation

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04879B, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jingjing Yu, Marius Gaedke, Satyajit Das, Daniel L. Stares, Christoph A. Schalley, Fredrik Schaufelberger
Dynamic covalent boronic ester bonds can pre-organise diol-containing threads and V-shaped boronic acid ligands towards mechanical interlocking. After interlocking, the pre-rotaxane could be modified to create many unique [2]rotaxanes architectures.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04026K, Edge Article
Open Access
Jacob A. Iannuzzelli, Rachel Bonn, Andrew S. Hong, Abhijith Saseendran Anitha, Jermaine L. Jenkins, Joseph E. Wedekind, Rudi Fasan
Cyclopeptide agents targeted against the −1 programmed ribosomal frameshifting stimulatory sequence RNA pseudoknot of SARS-CoV-2 were discovered by screening a multiplexed phage display library of genetically encoded peptide macrocycles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A polymer deposition-mediated surface-charge reformation strategy: reversing the MOF biomineralization behavior

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05935B, Edge Article
Open Access
Yanbin Xu, Huangsheng Yang, Anlian Huang, Linjing Tong, Wei Huang, Guosheng Chen, Wei Yi, Siming Huang, Gangfeng Ouyang
A biocompatible polymer deposition-mediated surface-charge reformation strategy is reported that enables the in-place MOF biomineralization onto different enzyme templates.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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CuBr-mediated surface-initiated controlled radical polymerization in air

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC06012A, Edge Article
Open Access
Menglu Chen, Shuai You, Tingting Guo, Haohao Ren, Longzu Zhu, Peize Wang, Wenbo Sheng, Chenliang Gong, Wei Li
CuBr-mediated surface-initiated controlled radical polymerization for polymer brushes with patterned and block architectures over large areas in air is reported.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Synergetic effect of mild hypothermia and antioxidant treatment on ROS-mediated neuron injury under oxygen-glucose deprivation investigated by scanning electrochemical microscopy

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05977H, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Junjie Zhang, Yulin Liu, Yuxiang Zhao, Siyu Zhang, Feng Xu, Fei Li
Ischemic stroke and reperfusion injury result in neuronal damage and dysfunction associated with oxidative stress, leading to overproduction of cellular reactive oxygen species (ROS) and reactive nitrogen species (RNS). In...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Mohammed Rafi and the rights of fictional characters




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Dabbling in different mediums

Beyond sharing her experience of working with the powerhouse combination of Alia Bhatt, Shah Rukh Khan and Gauri Shinde in the upcomingDear Zindagi, Ira Dubey talks about her undying love for theatre and more




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Share Market Highlights 18 April 2024: Sensex falls 330 pts, Nifty at 22,000; media, metal stocks shine, FMCG, healthcare drag

Sensex, Nifty updates on 18th April 2024: Equity benchmarks BSE Sensex and NSE Nifty extended losses on Thursday. As per provisional figures, BSE Sensex fell 332.23 pts or 0.46 per cent to trade at 72,611.45 as of 3.35 pm and Nifty 50 declined 103.70 pts or 0.47 per cent to trade at 22,044.20., Bharti Airtel, Power Grid Corp, M&M, BPCL, and Tata Steel were the top gainers, while Nestle, Apollo Hospitals, Axis Bank, HCL Technologies, and ONGC were the major laggards. The stocks that hit a 52-week high on the NSE include AAA Tech (19.33 per cent), Just Dial (12.95 per cent), Indo Tech (10 per cent) and Hi-Tech Gear (10 per cent).




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Secrets of the Red Lantern Named Best Asian Cookbook of 2008

Secrets of the Red Lantern: Stories and Vietnamese Recipes from the Heart
by Pauline Nguyen has been named Best Asian Cookbook of 2008 by epicurious.com:


BEST ASIAN
Secrets of the Red Lantern
by Pauline Nguyen (Andrews McMeel Publishing)
Recipe to try: Salt and Pepper Tofu

Whether you want amazingly accessible Vietnamese recipes or just a good, honest family story with food, this Sydney restaurateur delivers. Her family memoir is a great tale of what immigrants both give up and gain in choosing (or not) to pack up and try another country, and if it's not always pretty, it is inspiring, especially with both vintage photos and pictures of the contemporary food Nguyen creates. The book is so beautiful you can almost taste the braised duck with ginger and scallions or the banana fritters.

http://www.epicurious.com/articlesguides/howtocook/cookbooks/bestof2008




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President Obama Election 2008 Named Best Seller

The New York Times Book Review of January 18, 2009 features President Obama Election 2008: A Collection of Newspaper Front Pages Selected by the Poynter Institute at #28 on the Paperback NonFiction Best Seller List

The election of Barack Obama as the first African-American president of the United States was a worldwide historic event resulting in perhaps some of the most important front pages in US history. President Obama Election 2008 is a collection of over seventy November 5th, 2008 newspaper front pages from around the world. There is no better statement of the emotion, excitement, and significance of this moment in history.

During his campaign for the White House, Barack Obama garnered an almost frenzied following. President Obama Election 2008 will be a cherished keepsake or gift for any of the millions of Americans who cast their vote for the 44th President of the United States. Here is the must-have commemorative book on this historic event.

  • Features over 70 historic newspaper front-pages from the day after the election, including international, campus, and ethnic publications.
  • Includes an introduction by Doonesbury creator Garry Trudeau.
  • Compiled by The Poynter Institute, a non-profit, non-partisan school of journalism.

About The Poynter Institute

Founded in 1975, The Poynter Institute is a school dedicated to teaching and inspiring journalists and media leaders. It promotes excellence and integrity in the practice of craft and in the practical leadership of successful businesses. It stands for a journalism that informs citizens and enlightens public discourse. It carries forward Nelson Poynter's belief in the value of independent journalism in the public interest. As a financially independent, nonprofit organization, The Poynter Institute is beholden to no interest except its own mission: to help journalists seek and achieve excellence.

To purchase: http://www.andrewsmcmeel.com/products/?isbn=0740784803



  • President Obama Election 2008
  • The New York Times Book Review
  • The Poynter Institute

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Bee & Me Named Best Seller

The New York Times Book Review of January 18, 2009 features Bee & Me at #8 on the Children’s Best Seller List

When a young boy discovers a bee trapped in his bedroom he hides for fear of being stung. But when the amiable bee frantically explains all that bees do, the boy comes to understand how good things come in different packages: "Bees make honey. That much we know. Bees also spread pollen, which makes all things grow."

The subject of honeybees' mysterious dwindling population throughout the world has been a growing concern in the news in recent years. Bee & Me brings the critical importance of bees to light for young children through the innovative, full color process of ANIMOTION™ in an engaging story of friendship and understanding. Bee & Me will charm readers while providing valuable information about how important bees are to sustainable agriculture. Bee & Me is sure to fascinate, entertain and engage readers of all ages.

Features:

  • Unique animated windows on almost every spread enhancing the action of the story.

    The first time ever that such a technique has been applied in full color through the ANIMOTION™ process.

  • Enchanting full color illustrations.
  • Special appendix full of fun and important bee facts.




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The Art and Soul of Baking Named Best How-To Book

Library Journal included The Art and Soul of Baking by Sur La Table with Cindy Mushet on its list of Best How-To Books of 2008.

This addition to renowned culinary authority Sur La Table's cookbook series, The Art and Soul of Baking (Andrews McMeel Publishing, LLC; $40.00 hardcover), guides readers through the world of baking, where the tantalizing aromas of chocolate, vanilla, butter, and cinnamon fill the air and tempt the palate. Whether turning out a rustic olive and thyme bread or crafting a show-stopping triple-layer chocolate cake, pastry chef and baking instructor Cindy Mushet provides indispensable tips and tricks to help home bakers achieve professional-looking—and professional-tasting—results.

More than 275 tested and delectable recipes cover all the bases from tasty pies, tantalizing tarts, melt-in-your-mouth meringues, and delicious cookies to more complicated creations such as flaky pastries, decadent cakes, and lighter-than-air soufflés. Novice bakers and pastry perfectionists alike will be tempted by such treats as Dulce De Leche Éclairs with Milk Chocolate Glaze; Pumpkin Spice Cake with Maple-Cream Cheese Frosting; Gingerbread Shortcakes with Caramelized Apples and Cider Sabayon; and Warm Cranberry Crumble Tart. Of course, there are savory recipes, too, including fragrant Parmesan-Herb Popovers; Potato, Onion, and Gruyère Galette; and a perfect Herbed Chicken Pot Pie. And for a delicious twist on tried-and-true favorites, there are recipes for Bananas Foster Bread Pudding; Citrus-Goat Cheese Cheesecake; Chocolate Velvet Pound Cake; and Peanut Butter Thumbprints with Peanut Caramel.




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Cool Jew Named National Jewish Book Award Finalist

Congratulations to author Lisa Alcalay Klug, recipient of an honor in the "Jewish Pulitzers." Her book, Cool Jew: The Ultimate Guide for Every Member of the Tribe, published by Andrews McMeel in September 2008, has been named a 2008 National Jewish Book Awards finalist.

Cool Jew is a loving and irreverent celebration of Jewish culture. In addition to its fervent call for positive Jewish identity and affiliation, and embrace of Jewish multiculturalism, language, and more, the 250-page humor book also chronicles contemporary Jewish arts and culture with approximately 400 images. These include original line drawings, vintage Israeli and Jewish posters, t-shirt designs, kabbalistic paintings from Israel, album covers, kitsch and more. Cool Jew also features extensive back-of-the-book resource guides on ways to enjoy Jewish community called "Da Tribe Online" and contemporary Jewish music called "Da Heebster Jewkebox."

Cool Jew placed in the category of "Contemporary Jewish Life and Practice." It is the only humor book among the 2008 National Jewish Book Award honorees.

Each year, the National Jewish Book Awards honor some of the best and most exciting authors in the field of Jewish literature. After more than fifty years of presenting these awards, hundreds of books have received the prestigious National Jewish Book Award, including titles by the top authors on the American Jewish literary scene. For the full list of winners and finalists, click here.

The 58th Annual National Jewish Book Awards Ceremony will be held at 7:30 pm, March 5th at the Center for Jewish History in New York City. The ceremony is free and open to the public.

This is the second honor for author Lisa Alcalay Klug since the September release of her first book. She was previously named Erma Bombeck Humor Writer of the Month by the University of Dayton.



  • Cool Jew
  • Jewish Book Awards
  • Lisa Alcalay Klug

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Bee & Me Named Publisher's Weekly Bestseller

Publisher’s Weekly’s Children’s Picture Book Bestsellers (2/16/09) features Bee & Me at #8

When a young boy discovers a bee trapped in his bedroom he hides for fear of being stung. But when the amiable bee frantically explains all that bees do, the boy comes to understand how good things come in different packages: "Bees make honey. That much we know. Bees also spread pollen, which makes all things grow."

The subject of honeybees' mysterious dwindling population throughout the world has been a growing concern in the news in recent years. Bee & Me brings the critical importance of bees to light for young children through the innovative, full color process of ANIMOTION™ in an engaging story of friendship and understanding. Bee & Me will charm readers while providing valuable information about how important bees are to sustainable agriculture. Bee & Me is sure to fascinate, entertain and engage readers of all ages.

Coming soon: Baby Turtle's Tale

This is something to "sea" and read. Full-color ani-motion technology comes alive and propels Baby Turtle's Tale, a lovely and touching story about a baby sea turtle hatching and making his way in the underwater world.

Elle McGuinness, the author of the well-received Bee & Me, takes us on the sea turtle's adventures from the beach to the reunion with his family on the coral reef.

Baby Turtle's Tale will appeal to young readers interested in preserving the environment and helping the plight of endangered species like sea turtles.

Features an educational appendix of fun and interesting facts about sea turtles




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The Art & Soul of Baking Named James Beard Nominee

The Art & Soul of Baking has been named a nominee in the James Beard Foundation Awards 2009 in the Books: Baking Category

The James Beard Foundation Awards shine a spotlight on the best and brightest talent in the food and beverage industry.

The winners will be announced May 4th at a Black Tie Ceremony in New York

The Art and Soul of Baking guides readers through the world of baking, where alluring aromas of chocolate, vanilla, and cinnamon fill the air and tempt the palate. Culinary authority Sur La Table teams with professional pastry chef and baking instructor Cindy Mushet to create the ultimate book for bakers. The Art and Soul of Baking demystifies the friendly science of baking through delicious recipes and photography sequences that illustrate proper techniques for carmelizing sugar, or working with croissant dough.



  • The Art and Soul of Baking

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Man armed with machete creates tension in Aluva




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Laugh in life: Kochi-based comedians Abhishek and Akshay on their latest show, their inspirations and more

The duo has been performing stand-up comedy for around three years now.




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Media rights cannot be restricted: Kerala High Court

Expression by the media of any definitive opinion regarding the guilt or innocence of a party in an ongoing criminal investigation will not get protection under Article 19(1)(a), observes an HC bench




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About 10 lakh tonnes of legacy waste awaiting scientific remediation




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HC allows medical termination of pregnancy of minor rape survivor

Division Bench passed the order while allowing an appeal filed against a single judge’s order declining permission. Medical board said that termination of pregnancy was most appropriate




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1,000 consumer clubs to be formed on campuses, says Kerala Minister




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Champions Way primed to deliver in the Governor’s Cup




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Knotty Charmer primed to deliver in the Rajyotsava Trophy




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QR code diktat to be widened for more medicines, says DCGI Raghuvanshi 

already Top 300 drug brands are already under mandatory QR code net 




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Aviation Minister proposes over 50 helicopter emergency medical units along highways

This initiative aims to enhance rapid medical assistance, particularly in remote areas, and align with global healthcare standards




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TN: Leopard kills dog at home stay in Valparai, locals demand immediate capture




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Bengal govt to bring exams in medical colleges under CCTV surveillance, live-streaming




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Ceiling prices of 8 common drugs raised by 50%, these medicines treat asthma, tuberculosis, others...

The National Pharmaceutical Pricing Authority (NPPA) has sanctioned the ceiling price hike for 11 formulations by 50 per cent in response to representations from drug makers.




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NIH clinical trial will test precision medicine treatments for myeloid cancers

NCI has launched myeloMATCH, a precision medicine treatment trial that will test treatment combinations targeting specific genetic changes in people with acute myeloid leukemia and myelodysplastic syndromes.




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Data | In Andhra Pradesh, rich districts such as West Godavari and Visakhapatnam, performed poorly on social indicators

Rich districts featured at the bottom half when categorised on health and education related parameters




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PM Modi on Chess Olympiad gold medals: ‘A new chapter in India’s sports trajectory’




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Chess | Vantika happy to have redeemed herself and aided in her team’s victory




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Deeply concerning: Usha slams executive committee members for not felicitating Olympic medallists

India secured six medals, including two historic bronze by young shooter Manu Bhaker, but Usha said the "EC does not want to celebrate their success" and it makes her "very sad."




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India stays on top of medals table




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World junior shooting championship | Aashima Ahlawat misses trap medal by a whisker




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From missing big medals to nailing the bigger one — the Swapnil story

The 50-metre rifle 3-position shooter, who lost the plot after being in pole position at major events in the run-up to the Olympic Games, turned it around with a podium performance in Paris as expert guidance, diligent preparation and Himalayan patience do the trick




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Under-23 World Wrestling Championships: Chirag Chikkara clinches gold as India shines with nine medals

Chirag Chikkara becomes the second Indian man, after Paris Olympics bronze medallist Aman Sehrawat, to win the gold at the U23 Championships.




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Qatar halts its mediation efforts on Gaza, says the Hamas office ‘no longer serves its purpose’

In Washington, a U.S. official said the Biden administration informed Qatar two weeks ago that the Hamas office's continued operation in Doha was no longer useful and the Hamas delegation should be expelled




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Canadian Foreign Ministry denies blocking Indian-diaspora media outlet Australia Today

The news site and video of media comments by both India’s Foreign Minister Jaishankar and Australia’s Foreign Minister Wong can be easily and freely viewed in Canada, the Ministry said




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Israeli strikes set off explosions in Beirut suburbs and kill 14 Palestinians in Gaza, medics say

The strike came hours after the Israeli military announced an expansion of the zone, where it has told Palestinians evacuating from other parts of Gaza to take refuge




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Eluru Government Medical College named after biochemist Yellapragada SubbaRow

SubbaRow, born in 1895 in Bhimavaram, is credited with discovering drugs for Filariasis and the role of ATP in muscular activity




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Lakshmi Parvathi flays coalition government for arrest of social media activists




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Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of L-lactate

Anal. Methods, 2024, 16,2077-2084
DOI: 10.1039/D4AY00041B, Paper
Wenjuan Wang, Danrong Chen, Yujiao Cai, Zijing Liu, Hongfen Yang, Hongbin Xie, Jinquan Liu, Shengyuan Yang
Here, we show a paper-based POCT sensor based on lactate dehydrogenase-mediated alginate gelation combined with visual distance reading and smartphone-assisted colorimetric dual-signal analysis to determine the concentration of L-lactate in yogurt samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Surface charge-induced electrospray for high-throughput analysis of complex samples and electrochemical reaction intermediates using mass spectrometry

Anal. Methods, 2024, 16,2002-2008
DOI: 10.1039/D4AY00276H, Communication
Yajie Huang, Yajun Zheng, Qianqian Zuo, Zhiming Zhang, Lixuan Zhu, Yun Li, Zhiping Zhang
A novel surface charge induced electrospray ionization is proposed due to its features of no contact between sample solution and metal electrode, fast analytical process (less than 40 s), and high analytical sensitivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rapid detection of monkeypox virus and differentiation of West African and Congo Basin strains using endonuclease restriction-mediated real-time PCR-based testing

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00492B, Paper
Juan Zhou, Fei Xiao, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Min Chen, Zheng Xu, Hui Huang, Yi Wang
A novel multiplex ET-PCR assay that integrates PCR amplification, restriction endonuclease cleavage and real-time fluorescence detection was devised to diagnose MPXV infection and distinguish the Congo Basin and West Africa MPXV strains.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A complementary method with PFBBr-derivatization based on a GC-EI-MS platform for the simultaneous quantitation of short-, medium- and long-chain fatty acids in murine plasma and feces samples

Anal. Methods, 2024, 16,2330-2339
DOI: 10.1039/D3AY02271D, Paper
Hong-Xu Zhou, Qing Jiang, Xin He, Xian Fu, Jun-Yan Liu
Fatty acids (FAs) are essential molecules in all organisms and are involved in various physiological and pathophysiological processes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages

Anal. Methods, 2024, 16,2359-2367
DOI: 10.1039/D4AY00151F, Paper
Dingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling Wu
Sartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The preparation of a boronate affinity-based controlled oriented imprinting coating on a silica nanoparticle surface for the separation and purification of shikimic acid in herbal medicine

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00219A, Paper
Yumin Yang, Daojin Li, Bingqian Liu
Shikimic acid (SA) is one of the most effective drugs against the A (H1N1) virus and has high medicinal value.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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​Regulation role: On the 2024 Medicine Nobel

The discovery of microRNA changed the understanding of gene regulation




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Biology transformed: On the Nobel Prize in chemistry

Nobel for determining protein structure recognises a big advance