ISLAMABAD: The State Bank of Pakistan’s Refinance Scheme for Small Businesses has so far failed to take off due to multiple reasons as the commercial banks are not designed and fully equipped to provide credit line to Small and Medium Enterprises .“The SBP’s RefinanceScheme for...

Reforming state-owned enterprises can be an extraordinarily complex activity but it is underpinned by a single clear goal.

How To Select or Change myMICROCHIP Preferences

ISLAMABAD: Chief Justice of the Islamabad High Court (IHC) Justice Athar Minallah on Friday converted the matter relating to delay in administration of justice into public interest litigation and sought reports from the interior secretary, the chief commissioner of Islamabad and judges of trial courts working within the IHC’s jurisdiction.

Chief Justice Minallah asked the police, district administration and federal government to explain why police reforms could not be enforced in the federal capital even though the law had been promulgated some 18 years ago.

The court framed six questions to be answered by these authorities, including why Police Order 2002 could not be implemented in Islamabad; why proper investigation training was not imparted to investigation officers; whether the code of criminal procedure 1898 and Qanoon-i-Shahadat [Evidence Act] of 1984 were still applicable; whether the state was responsible for delay in administration of justice and whether victims of delayed justice could seek remedy from any forum.

The court appointed criminologist Dr Shoaib Suddle, Kamaluddin Tippu, director general of the National Police Bureau, superintendent of Adiala Jail and vice chairmen of the Pakistan Bar Council and Islamabad Bar Council as amici curiae in the matter.

Further hearing was adjourned to May 14.

During the hearing, the inspector general of Islamabad police submitted a report on the problems arising during investigation of crimes which hindered administration of justice.

In the report, the IG said that the investigation officer (IO) of a case had to pay Rs5,000 parcel fee from his own pocket to send evidence to a forensic laboratory for analysis.

“There should not be any laboratory fee or it should be responsibility of the district administration [to pay the fee],” he said.

The IG noted that it took around two months to send evidence to laboratory for analysis. “An IO should be given the authority to send evidence to a laboratory without waiting for the approval of high officials,” he suggested.

Similarly, he said, an IO paid Rs15,000 for preparation of a sketch of a suspect believed to have committed a crime. “Such a sketch should be prepared within two days.”

The report said that plaintiffs did not cooperate with police after registration of first information reports.

The absence of a forensic laboratory in Islamabad, lawyers’ strikes and deployment of police personnel for special duties also delayed investigation process and subsequently trials, the report said.

Earlier, acquitting a murder suspect Chief Justice Minallah had observed that the existing criminal justice system had failed to deliver and it was on the verge of collapse.

The court had observed that the existing criminal justice system failed to prevent and prosecute crime and it was perpetuating miscarriages of justice.

It had noted that low-paid investigating officers did not have sufficient resources to visit the crime scene when a crime was reported, let alone sending the sealed samples and arranging the payment of the fee to a laboratory for conducting forensic examinations.

Published in Dawn, May 9th, 2020

The Chinese government policy of racial and religious profiling has forced young Uyghurs to leave China and remain in exile.

"I felt that they listened to what I was trying to say, and it shows that they do value democracy here in Taiwan."

One day after saying that the White House COVID-19 task force would be winding down, President Donald Trump said Wednesday it would continue indefinitely but focus more on rebooting the economy.

This video lays out Domestic Preference and the types of conditions for when borrowers can introduce it into the bidding process.

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With the Narendra Modi government taking charge on Tuesday, real estate players hope the sector will get due priority, which will help bring the economy back to 8-9 percent growth. “The new government will pave way for realty reforms and take concrete steps to implement its promise given in the BJP manifesto to ensure housing for all in eight years,” Confederation of Real Estate Developers’ Associations of India (Credai) Lalit Kumar Jain said. The merger of Housing and Urban Development Department will ensure coordination and proper control, he said. “The new government will bring in a positive change to developers and buyers in the otherwise dark era that has been […]

Heritage homes are fast becoming the favourite hunting grounds of luxury brands scouting for premium retailing space in India, where suitable high-end malls are too few and the sales potential at five-star hotels is still uncertain. When designer wear brand Kimaya Fashions searched for a store in Hyderabad, it settled on a 16,000-sq ft bungalow in the upscale Jubilee Hills, in a property with floor area nearly three times the size of its average outlets. French luxury brand Hermes also moved into a Victorian property in Mumbai’s Horniman Circle to retail its popular Birkin bags. “It’s not necessarily out of choice,” says Pradeep Hirani, managing director of Kimaya Fashions, “This […]

This paper describes the implementation of the Certificate in Educational Studies in Leadership (CESL) in the Philippines as a professional development initiative delivered in a customized blended learning mode.

The European experience could be useful to inspire the future evolution of the Chiang Mai Initiative Multilateralization in the ASEAN+3 membership.

Regulatory reforms should focus on building up market competition, which indirectly forces state-owned enterprises to improve their operation toward efficiency.

The European experience could be useful to inspire the future evolution of the Chiang Mai Initiative Multilateralization in the ASEAN+3 membership.

Regulatory reforms should focus on building up market competition, which indirectly forces state-owned enterprises to improve their operation toward efficiency.

MUMBAI/BANGALORE: Multinational companies are increasingly buying properties to set up their offices instead of leasing offices as they preferred for years, marking a strategic shift that signals the growing importance of the Indian market and the long-term commitment of the global firms. Foreign firms including GlaxoSmithKline Pharma, Sanofi Aventis, Adobe, Honeywell, SanDisk and Amazon have recently bought office space in India. MNCs accounted for 35% of total commercial asset sales in the country in the first three months of 2014, according to a report by real estate services firm Cushman & Wakefield. In 2012, MNCs contributed as much as 60% to the total commercial asset sales, backed by two deals […]

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Music has the ability to uplift, refresh, and redefine our lives. As Elton John once said, “Music has healing power,” so it’s no surprise that concert ticket sales in North America amounted to $8 billion in 2017. Not only does attending a musical ...

Brazil's Bela Vista Biological Refuge Veterinarian Pedro Enrrique Ferreira says the Harpy Eagle hatchling born on April 26 only weighs 150 grams now but could one day grow to weigh some 20 pounds.

Brazil's Bela Vista Biological Refuge Veterinarian Pedro Enrrique Ferreira says the Harpy Eagle hatchling born on April 26 only weighs 150 grams now but could one day grow to weigh some 20 pounds.

Refugees at the Zaatari camp in Jordan have designed a robot prototype made from LEGOs, which automatically dispenses sanitizer to avoid contact with the bottle and help prevent the spread of the coronavirus.

Refugees at the Zaatari camp in Jordan have designed a robot prototype made from LEGOs, which automatically dispenses sanitizer to avoid contact with the bottle and help prevent the spread of the coronavirus.

South Africa's central bank has temporarily prohibited the use of debt issued by the Land Bank as collateral after the state agricultural lender was downgraded deeper into junk status and missed $2.7 billion in loan repayments.

Brazil's Bela Vista Biological Refuge Veterinarian Pedro Enrrique Ferreira says the Harpy Eagle hatchling born on April 26 only weighs 150 grams now but could one day grow to weigh some 20 pounds.

Black paint usually absorbs heat, but a new two-layer polymer paint reflects infrared light and keeps objects 16°C cooler, which could help make buildings more energy efficient

Title: Americans Still Split Over New Health Reform Law
Category: Health News
Created: 4/30/2010 8:10:00 AM
Last Editorial Review: 4/30/2010 12:00:00 AM

Title: AHA News: Firefighter In Need of a New Heart Got By With a Little Help From His Friends
Category: Health News
Created: 4/24/2020 12:00:00 AM
Last Editorial Review: 4/27/2020 12:00:00 AM

As of August 2016, PMC is home to four million articles! To make this wealth of full-text content easier to navigate, PMC has rolled out a few updates:

1) Search Result Filters
On all search results pages, you will now see filters (similar to PubMed’s filters) on the left-hand side that allow you to filter your results by article attributes, publication date, research funder, and search fields. These filters replace the Limits page and allow you to more readily:

• find open access articles (PMC has more than 1.35 million open access articles that can be reused according to their license statements),
• explore PMC’s rich historical content from NLM's back issue digitization project,
• browse research supported by PMC-participating funding organizations (click "Customize" to view additional funder options),
• and much more.

You can now also quickly add articles that are under a 12-month or less embargo in PMC to your search results by selecting the “Include embargoed articles” filter option under Text Availability. See the PMC User Guide for more information on these filters.

2) Reference List Display
Using related article data available in PMC, articles that cite papers that have been either retracted or named in a Findings of Research Misconduct issued by the HHS Office of Research Integrity and not yet retracted will now include a red hyperlink to the relevant notice directly from the article’s reference list. This update will help users more easily identify post-publication updates to existing research.

Title: Pick Summer Camps Carefully When Your Kid Has Allergies, Asthma
Category: Health News
Created: 2/29/2020 12:00:00 AM
Last Editorial Review: 3/2/2020 12:00:00 AM

Purpose: The purpose of this study was to analyze associations between the oral health literacy of refugees and two oral health outcomes: dental care utilization and oral health self-efficacy.Methods: A convenience sample of refugees in the greater Los Angeles area attending English as a second language (ESL) classes sponsored by two refugee assistance organizations was used for this cross-sectional, correlational study. Participants responded to a questionnaire using items from the Health Literacy in Dentistry (HeLD) scale, in addition to items concerning dental care utilization and oral health self-efficacy. Descriptive statistics, chi-square and Fisher's Exact tests were used to analyze results.Results: Sixty-two refugees volunteered to participate (n=62). A majority of the respondents were female from Iraq or Syria, and selected the item “with little difficulty” for all oral health literacy tasks. In regards to dental care utilization, more than half of the respondents were considered high utilizers (63%, n=34) meaning they had visited a dental office within the last year; while a little more than one-third (37%, n=20), were low utilizers, indicating they had either never been to a dental office or it had been more than one year since they had dental treatment. Statistical analysis showed associations between oral health literacy and dental care utilization. However, few associations between oral health literacy and oral health self-efficacy were identified (p=0.0045).Conclusions: Results support the provision of easily obtainable and understandable oral health information to increase oral health literacy and dental care utilization among refugee populations. Future research is needed to examine the oral health literacy among refugees resettling in the United States.

Fredrik Christiansen, Kate R. Sprogis, Jasmin Gross, Juliana Castrillon, Hunter A. Warick, Eva Leunissen, and Susan Bengtson Nash

An animal's body condition provides valuable information for ecophysiological studies, and is an important measure of fitness in population monitoring and conservation. While both the external body shape of an animal and its internal tissues (i.e. fat content) can be used as a measure of body condition, the relationship between the two is not always linear. We compared the morphological body condition (external metric obtained through aerial photogrammetry) of migrating humpback whales (Megaptera novaeangliae) with their outer blubber lipid concentration (internal metric obtained through blubber biopsy sampling) off the coast of south-west Australia early and late in the breeding season (spanning ~4.5 months). The external body condition index of juvenile and adult humpback whales decreased by 26.9 (from 18.8% to –8.1%) and 12.0 percentage points (from 8.6% to –3.4%), respectively, between the early and late phase. In contrast, we found no intra-seasonal change in blubber lipid concentration, and no difference between reproductive classes (juveniles, adults and lactating females); however, the small sample size prevented us from effectively testing these effects. Importantly, however, in the 33 animals for which paired metrics were obtained, we found no correlation between the morphometric body condition index and the blubber lipid concentration of individual whales. The lack of a linear relationship suggests that changes in outer blubber lipid concentration do not reflect external changes in body shape, thus limiting the utility of outer blubber lipid reserves for individual body condition evaluation. The wider spectrum of change in body morphometry captured with aerial photogrammetry supports the use of body morphometry as a reliable and well-tested method.

Scarlet J. Park and William W. Ja

Factors that mediate ethanol preference in Drosophila melanogaster are not well understood. A major confound has been the use of diverse methods to estimate ethanol consumption. We measured fly consumptive ethanol preference on base diets varying in nutrients, taste, and ethanol concentration. Both sexes showed ethanol preference that was abolished on high nutrient concentration diets. Additionally, manipulating total food intake without altering the nutritive value of the base diet or the ethanol concentration was sufficient to evoke or eliminate ethanol preference. Absolute ethanol intake and food volume consumed were stronger predictors of ethanol preference than caloric intake or the dietary caloric content. Our findings suggest that the effect of the base diet on ethanol preference is largely mediated by total consumption associated with the delivery medium, which ultimately determines the level of ethanol intake. We speculate that a physiologically relevant threshold for ethanol intake is essential for preferential ethanol consumption.

Dual amylin and calcitonin receptor agonists (DACRAs) are novel candidates for treatment of type 2 diabetes and obesity because of their beneficial effects on body weight, blood glucose, insulin sensitivity, and food preference, at least short-term. DACRAs activate the receptors for a prolonged time period, resulting in metabolic effects superior to those of amylin. Because of the prolonged receptor activation, different dosing intervals and, hence, less frequent receptor activation might change the efficacy of DACRA treatment in terms of weight loss and food preference. In this study, we compared daily dosing to dosing every other day with the aim of understanding the optimal balance between efficacy and tolerability. Obese and lean male Sprague-Dawley rats were treated with the DACRA KBP-088, applying two different dosing intervals (1.5 nmol/kg once daily and 3 nmol/kg every other day) to assess the effect on body weight, food intake, glucose tolerance, and food preference when given the choice between chow (13% fat) and a high-fat diet (60% fat). Treatment with KBP-088 induced significant weight loss, reduction in adiposity, improvement in glucose control, and altered food preference toward food that is less calorie-dense. KBP-088 dosed every other day (3 nmol/kg) was superior to KBP-088 once daily (1.5 nmol/kg) in terms of weight loss and improvement of food preference. The beneficial effects were evident in both lean and obese rats. Hence, dosing KBP-088 every other day positively affects overall efficacy on metabolic parameters regardless of the lean/obese state, suggesting that less-frequent dosing with KBP-088 could be feasible.

Monoclonal antibodies (mAbs) against programmed cell death 1 (PD-1), such as nivolumab and pembrolizumab, are associated with high response rates in patients with relapsed or refractory classic Hodgkin lymphoma (HL). To date, no prognostic factor for overall survival (OS) has been established with these agents in HL. We examined whether the first early response assessment evaluated using ¹⁸F-FDG PET/CT may be associated with OS in this setting. Methods: This retrospective study included 45 patients from 34 institutions. In a masked, centralized review, 3 independent radiologists classified PET/CT scans obtained at a median of 2.0 mo (interquartile range, 1.7–3.7 mo) after nivolumab initiation using existing criteria (i.e., 2014 Lugano classification and 2016 LYRIC). Patients were classified according to 4 possible response categories: complete metabolic response (CMR), partial metabolic response (PMR), no metabolic response (NMR), or progressive metabolic disease (PMD). Because the OS of patients with NMR and PMR was similar, they were grouped together. OS was estimated using the Kaplan–Meier method and compared between groups using log-rank testing. Results: Eleven patients (24%) died after a median follow-up of 21.2 mo. The classification was identical between Lugano and LYRIC because all 16 progression events classified as indeterminate response per LYRIC were confirmed on subsequent evaluations. Both Lugano and LYRIC classified patients as CMR in 13 cases (29%), PMD in 16 (36%), NMR in 4 (9%), and PMR in 12 (27%). The 2-y OS probability was significantly different in patients with PMD (0.53; 95% confidence interval [95%CI], 0.32–0.87), NMR or PMR (0.80; 95%CI, 0.63–1.00), and CMR (1.00; 95%CI, 1.00–1.00) in the overall population (P = 0.02, 45 patients), as well as according to a landmark analysis at 3 mo (P = 0.05, 32 patients). Conclusion: In relapsed or refractory HL patients treated with anti-PD-1 mAbs, the first early PET/CT assessment using either Lugano or LYRIC predicted OS and allowed early risk stratification, suggesting that PET/CT might be used to develop risk-adapted strategies.

Impaired baroreflex sensitivity (BRS) predicts cardiovascular mortality and is prevalent in long-term diabetes. We determined spontaneous BRS in patients with recent-onset diabetes and its temporal sequence over 5 years by recording beat-to-beat blood pressure and R-R intervals over 10 min. Four time domain and four frequency domain BRS indices were computed in participants from the German Diabetes Study baseline cohort with recent-onset type 1/type 2 diabetes (n = 206/381) and age-matched glucose-tolerant control subjects (control 1/control 2: n = 65/83) and subsets of consecutive participants with type 1/type 2 diabetes who reached the 5-year follow-up (n = 84/137). Insulin sensitivity (M-value) was determined using a hyperinsulinemic-euglycemic clamp. After appropriate adjustment, three frequency domain BRS indices were reduced in type 2 diabetes compared with control 2 and were positively associated with the M-value and inversely associated with fasting glucose and HbA_1c (P < 0.05), whereas BRS was preserved in type 1 diabetes. After 5 years, a decrease in one and four BRS indices was observed in patients with type 1 and type 2 diabetes, respectively (P < 0.05), which was explained by the physiologic age-dependent decline. Unlike patients with well-controlled recent-onset type 1 diabetes, those with type 2 diabetes show early baroreflex dysfunction, likely due to insulin resistance and hyperglycemia, albeit without progression over 5 years.

Hundreds of thousands of Rohingya refugees arrived in Bangladesh within weeks in fall 2017, quickly forming large settlements without any basic support. Humanitarian first responders provided basic necessities including food, shelter, water, sanitation, and health care. However, the challenge before them—a vast camp ravaged by diphtheria and measles superimposed on a myriad of common pathologies—was disproportionate to the resources. The needs were endless, resources finite, inadequacies abundant, and premature death inevitable. While such confines force unimaginable choices in resource allocation, they do not define the humanitarian purpose—to alleviate suffering and not allow such moral violations to become devoid of their horrifying meaning. As humanitarian workers, we maintain humanity when we care, commit, and respond to moral injustices. This refusal to abandon others in desperate situations is an attempt to rectify injustices through witnessing and solidarity. When people are left behind, we must not leave them alone.

In 2016, Rose Lamont and Tana Fishman were the first patient-clinician dyad from outside North America to attend the North American Primary Care Research Group (NAPCRG) Patient and Clinician Engagement Program workshop. They returned to New Zealand inspired and formed the Pacific People’s Health Advisory Group and a Pacific practice-based research network (PBRN). They are guided by the principles of co-design, and the Samoan research framework fa’afaletui, which emphasizes a collective approach and importance of reciprocity and relationships. Their collective inquiry aims to reduce health inequalities experienced by Pacific people in South Auckland. Their community group members and PBRN are generating research questions being answered by university-based graduate students. When they embarked, they knew not the direction in which they headed. With guidance, their community members and clinicians have led the way. By giving everyone a say in where they are going and how they get there, they are modeling what they wish to achieve—an egalitarian approach which decreases disparities for Pacific people.

Few health care professionals receive comprehensive training in how to effectively help their patients with obesity. Yet patients are often wanting, needing, and looking for help when they go to the doctor. We, as a group of patients with obesity, share our common experiences and needs when going to the doctor from a place of honesty and hope, with the assumption that clinicians want to know what their patients really think and feel. Our "wish list" for a treatment plan may represent an ideal, but our hope is that our language will speak to clinicians about how they can help their patients manage their obesity.