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The youngest sex chromosomes on the block, and how to test a Zika vaccine without Zika cases

Strawberries had both male and female parts, like most plants, until several million years ago. This may seem like a long time ago, but it actually means strawberries have some of the youngest sex chromosomes around. What are the advantages of splitting a species into two sexes? Host Sarah Crespi interviews freelance journalist Carol Cruzan Morton about her story on scientists’ journey to understanding the strawberry’s sexual awakening. In 2016, experimental Zika vaccines were swiftly developed in response to the emergence of serious birth defects in the babies of infected woman. Two years after the height of Zika cases, there’s so little spread of the virus in the Americas that it has stymied vaccine trials. Researchers hope to overcome this hurdle with “human challenge experiments”—vaccinating people, then intentionally infecting them with Zika to see whether they’re protected from the virus. Meagan Cantwell talks with staff writer Jon Cohen about his news story that highlights the risks and rewards of human challenge experiments. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Public domain; Music: Jeffrey Cook]




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The future of PCB-laden orca whales, and doing genomics work with Indigenous people

Science has often treated Indigenous people as resources for research—especially when it comes to genomics. Now, Indigenous people are exploring how this type of study can be conducted in a way that respects their people and traditions. Meagan Cantwell talks with contributing correspondent Lizzie Wade about a summer workshop for Indigenous scientists that aims to start a new chapter in genomics. We’ve known for decades that PCBs—polychlorinated biphenyls—are toxic and carcinogenic. In the 1970s and 1980s, these compounds were phased out of use in industrial and electronic applications, worldwide. But they are still in the environment—in soil and air—and in animal tissues, particularly those of killer whales. These toxic compounds start out at minute levels in tiny organisms, but as the small are eaten by the slightly larger, the PCB concentration increases—from plankton, to fish, to seals—until you are at killer whales with PCB-packed blubber. Ailsa Hall, director of the Sea Mammal Research Unit at St. Andrews University in the United Kingdom, talks with host Sarah Crespi about her group’s work measuring PCB levels in different killer whale populations and calculating the effect of PCBs on those populations 100 years from now. In this month’s book segment, Jen Golbeck interviews Damon Centola about his book How Behavior Spreads: The Science of Complex Contagions. You can listen to more books segment and read more reviews on our books blog, Books et al.  This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts About the Science Podcast [Image: Public domain; Music: Jeffrey Cook] 




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What we can learn from a cluster of people with an inherited intellectual disability, and questioning how sustainable green lawns are in dry places

A small isolated town in Colombia is home to a large cluster of people with fragile X syndrome—a genetic disorder that leads to intellectual disability, physical abnormalities, and sometimes autism. Spectrum staff reporter Hannah Furfaro joins host Sarah Crespi to discuss the history of fragile X in the town of Ricaurte and the future of the people who live there. Also this week, we talk about greening up grass. Lawns of green grass pervade urban areas all around the world, regardless of climate, but the cost of maintaining them may outweigh their benefits. Host Meagan Cantwell talks with Maria Ignatieva of The University of Western Australia in Perth and the Swedish University of Agricultural Sciences in Uppsala about how lawns can be transformed to contribute to a more sustainable future. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Adam Kerfoot-Roberts/Flickr; Music: Jeffrey Cook]




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Measuring earthquake damage with cellphone sensors and determining the height of the ancient Tibetan Plateau

In the wake of a devastating earthquake, assessing the extent of damage to infrastructure is time consuming—now, a cheap sensor system based on the accelerometers in cellphones could expedite this process. Host Sarah Crespi talks with Contributing Correspondent Lizzie Wade about how these sensor systems work and how they might assist communities after an earthquake. In another Earth-shaking study, scientists have downgraded the height of the ancient Tibetan Plateau. Most reconstructions estimate that the “rooftop of the world” reached its current height of 4500 meters about 40 million years ago, but a new study suggests it was a mere 3000 meters high during this period. Host Meagan Cantwell speaks with Svetlana Botsyun, a postdoctoral researcher at Tübingen University in Germany, about her team’s new approach to studying paleoelevation, and how a shorter Tibetan Plateau would have impacted the surrounding area’s climate. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Martin Luff/Flickr; Music: Jeffrey Cook]




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Nonstick chemicals that stick around and detecting ear infections with smartphones

The groundwater of Rockford, Michigan, is contaminated by per- and polyfluoroalkyl substances, chemicals found in everything from nonstick pans to dental floss to—in the case of Rockford—waterproofing agents from a shoe factory that shut down in 2009. Science journalist Sara Talpos talks with host Meagan Cantwell about how locals found the potentially health-harming chemicals in their water, and how contamination from nonstick chemicals isn’t limited to Michigan. Also this week, host Sarah Crespi talks with Shyamnath Gollakota of the University of Washington in Seattle about his work diagnosing ear infections with smartphones. With the right app and a small paper cone, it turns out that your phone can listen for excess fluid in the ear by bouncing quiet clicks from the speaker off the eardrum. Clinical testing shows the setup is simple to use and can help parents and doctors check children for this common infection. This week’s episode was edited by Podigy. Ads on this show: Science Rules! podcast with Bill Nye Download the transcript (PDF)  Listen to previous podcasts. About the Science Podcast [Image: Dennis Wise/University of Washington; Music: Jeffrey Cook]




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Converting carbon dioxide into gasoline, and ‘autofocal’ glasses with lenses that change shape on the fly

Chemists have long known how to convert carbon dioxide into fuels—but up until now, such processes have been too expensive for commercial use. Staff Writer Robert Service talks with host Sarah Crespi about using new filters and catalysts to close the gap between air-derived and fossil-derived gasoline.   Also this week, host Sarah Crespi talks with Nitish Padmanaban of Stanford University in Palo Alto, California, about replacing bifocals with “autofocals.” These auto-focusing glasses track your eye position and measure the distance to the visual target before adjusting the thickness of their liquid lenses. The prototype glasses have an onboard camera and batteries that make them particularly bulky; however, they still outperformed progressive lenses in tests of focus speed and acuity. This week’s episode was edited by Podigy.   Download a transcript (PDF) Listen to previous podcasts.   About the Science Podcast  




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Next-generation cellphone signals could interfere with weather forecasts, and monitoring smoke from wildfires to model nuclear winter

In recent months, telecommunications companies in the United States have purchased a new part of the spectrum for use in 5G cellphone networks. Weather forecasters are concerned that these powerful signals could swamp out weaker signals from water vapor—which are in a nearby band and important for weather prediction. Freelance science writer Gabriel Popkin joins host Sarah Crespi to talk about the possible impact of cellphone signals on weather forecasting and some suggested regulations. In other weather news this week, Sarah talks with Pengfei Yu, a professor at Jinan University in Guangzhou, China, about his group’s work using a huge smoke plume from the 2017 wildfires in western Canada as a model for smoke from nuclear bombs. They found the wildfire smoke lofted itself 23 kilometers into the stratosphere, spread across the Northern Hemisphere, and took 8 months to dissipate, which line up with models of nuclear winter and suggests these fires can help predict the results of a nuclear war. This week’s episode was edited by Podigy. Ads on this week’s show: KiwiCo.com Download the transcript (PDF)  Listen to previous podcasts. About the Science Podcast




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Studying human health at 5100 meters, and playing hide and seek with rats

In La Rinconada, Peru, a town 5100 meters up in the Peruvian Andes, residents get by breathing air with 50% less oxygen than at sea level. International News Editor Martin Enserink visited the site with researchers studying chronic mountain sickness—when the body makes excess red blood cells in an effort to cope with oxygen deprivation—in these extreme conditions. Martin talks with host Sarah Crespi about how understanding why this illness occurs in some people and not others could help the residents of La Rinconada and the 140 million people worldwide living above 2500 meters. Read the whole special issue on mountains.  Sarah also talks with Annika Stefanie Reinhold about her work at the Bernstein Center for Computational Neuroscience in Berlin training rats to play hide and seek. Surprisingly, rats learned the game easily and were even able to switch roles—sometimes playing as the seeker, other times the hider. Annika talks with Sarah about why studying play behavior in animals is important for understanding the connections between play and learning in both rats and humans. This week’s episode was edited by Podigy. Ads on this week’s show: MOVA Globes; Kroger’s Zero Hunger, Zero Waste campaign Download a transcript (PDF)  Listen to previous podcasts. About the Science Podcast [Image: Tambako The Jaguar/Flickr; Music: Jeffrey Cook]




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Cooling Earth with asteroid dust, and 3 billion missing birds

On this week’s show, science journalist Josh Sokol talks about a global cooling event sparked by space dust that lead to a huge shift in animal and plant diversity 466 million years ago. (Read the related research article in Science Advances.) And I talk with Kenneth Rosenberg, an applied conservation scientist at Cornell University, about steep declines in bird abundance in the United States and Canada. His team estimates about 3 billion birds have gone missing since the 1970s. This week’s episode was edited by Podigy. Ads on this week’s show: MOVA Globes; KiwiCo.com Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Public domain; Music: Jeffrey Cook]




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Fighting cancer with CRISPR, and dating ancient rock art with wasp nests

On this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to talk about a Science paper that combines two hot areas of research—CRISPR gene editing and immunotherapy for cancer—and tests it in patients. Sarah also talks with Damien Finch, a Ph.D. candidate in the School of Earth Sciences at the University of Melbourne, about the Kimberly region of Australia and dating its ice age cave paintings using charcoal from nearby wasp nests. This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).




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Why some diseases come and go with the seasons, and how to develop smarter, safer chemicals

On this week’s show, host Joel Goldberg gets an update on the coronavirus pandemic from Senior Correspondent Jon Cohen. In addition, Cohen gives a rundown of his latest feature, which highlights the relationship between diseases and changing seasons—and how this relationship relates to a potential coronavirus vaccine. Also this week, from a recording made at this year’s AAAS annual meeting in Seattle, host Meagan Cantwell speaks with Alexandra Maertens, director of the Green Toxicology initiative at Johns Hopkins University, Baltimore, about the importance of incorporating nonanimal testing methods to study the adverse effects of chemicals. This week’s episode was produced with help from Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast [Image: Let Ideas Compete/Flickr; Music: Jeffrey Cook] 




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Malaika shares a pic with a positive message

The ongoing lockdown due to the coronavirus pandemic has brought everyone’s lives to a standstill. Bollywood celebrities are trying to make the most of their quarantine time. They have been sharing regular updates on social media and entertaining their fans. From cooking to doing household chores, even the B-town celebs have been exploring new things at home.




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Throwback pic of Rishi with Bachchans, Alia

Rishi Kapoor's daughter Riddhima Kapoor Sahni arrived in Mumbai from Delhi on 3rd May to be with her mother Neetu Kapoor and brother Ranbir Kapoor after the demise of the legendary actor on April 30.




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Ariana-Justin's anthem 'Stuck with U'

Pop sensations Ariana Grande and Justin Bieber have teamed up for a song titled as 'Stuck with U' which has been winning over the internet. Touted as the quarantine anthem, the popular singers have come together to raise funds for the children of frontline workers fighting coronavirus.




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Zaheer Iqbal on his bond with his mother

This year Mother’s Day is going to be extra special for everyone. Due to the ongoing lockdown because of coronavirus pandemic, everyone will be spending some extra time with their mothers. Bollywood celebrities too who hardly get the time to be with their families will be able to spend quality time with their dear mommies.




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Riddhima's throwback pic with Neetu and Rishi

Riddhima Kapoor Sahni has been taking to social media and sharing unseen pictures in memory of her late father Rishi Kapoor. While the entire Kapoor clan is still trying to get over the massive loss, Riddhima has managed to travel from Delhi to Mumbai amidst the lockdown to be by her mother's side.




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‘Comply with COVID 19 safety protocol’

TIRUCHIThe Tiruchi Corporation has directed all its contractors to strictly adhere to all safety protocols prescribed in view of the COVID 19 pandemic




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Product :: Foundations of Digital Art and Design with Adobe Creative Cloud, 2nd Edition




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Product :: Foundations of Digital Art and Design with Adobe Creative Cloud, 2nd Edition




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Fast determination of five chiral antipsychotic drugs using dispersive liquid–liquid microextraction combined with capillary electrophoresis

Anal. Methods, 2020, 12,2002-2008
DOI: 10.1039/C9AY02776A, Paper
Ming-Mu Hsieh, Tai-Chia Chiu, Szu-Hua Chen
This study developed a new method for the extraction, clean up, chiral separation, and determination of five pairs of phenothiazine drugs using ultrasound-assisted dispersive liquid–liquid microextraction combined with capillary electrophoresis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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3D-printed microfluidic device with in-line amperometric detection that also enables multi-modal detection

Anal. Methods, 2020, 12,2046-2051
DOI: 10.1039/D0AY00368A, Technical Note
Elizabeth A. Hayter, Andre D. Castiaux, R. Scott Martin
A 3D-printed microfluidic device with amperometric detection employs a parallel-opposed electrode configuration, with threaded electrodes being in contact with the flow stream. This makes downstream detection of ATP via chemiluminescence possible.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A simple and rapid method for blood plasma separation driven by capillary force with an application on protein detection

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00240B, Paper
Qingxue Gao, Yongjia Chang, Qingmei Deng, Hui You
Blood plasma separation is a vital sample pre-treatment procedure for microfluidic devices of blood diagnostic, which requires reliability and speediness. In this work, we propose a novel and simple method...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effective methods for the determination of triphenyltin residues in surface water and soil samples by high-performance liquid chromatography with tandem mass spectrometry

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00329H, Paper
Gabriel C. dos Santos, Állisson A. da S. Avellar, Rômulo de O. Schwaickhardt, Nelson M. G. Bandeira, Filipe F. Donato, Osmar D. Prestes, Renato Zanella
Monitoring of triphenyltin (TPhT) in the environment, particularly to control its misuse in agriculture, is of great importance because of its high toxicity.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Direct measurement of Cu and Pb isotopic ratios without column chemistry for bronzes using MC-ICP-MS

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00561D, Paper
Zhian Bao, Chunlei Zong, Peng Liang, Yan Zhang, Kaiyun Chen, Honglin Yuan
This study presents a practical method for high-precision Cu and Pb isotope determination without column chemistry for bronzes using MC-ICP-MS. The standard-sample bracketing method combined with Ga internal normalization (SSBIN)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chiral separations with crosslinked cellulose derivatives attached onto hybrid silica monolith particles via thiol-ene click reaction

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00772B, Paper
Yuhong Zhou, Qian Liang, Zhilun Zhang, Zhaodi Wang, Mingxian Huang
Hybrid silica monolith containing vinyl groups was synthesized by a sol-gel method and then ground and treated, yielding silica particles with 3-5 μm in particles size and 10-20 nm in...
The content of this RSS Feed (c) The Royal Society of Chemistry




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In situ imaging of intracellular human telomerase RNA with molecular beacon-functionalized gold nanoparticles

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00461H, Paper
Tao Xie, Ziyan Fan, Ruilong Zhang, Xiaohe Tian, Guangmei Han, Zhengjie Liu, Zhongping Zhang
We develop molecular beacon-functionalized gold nanoparticles for in situ human telomerase RNA imaging in live cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Towards simultaneous quantification of protease inhibitors and inflammatory biomarkers in serum for people living with HIV

Anal. Methods, 2020, 12,2196-2196
DOI: 10.1039/D0AY90050H, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Pengyi Wang, Charles S. Venuto, Raymond Cha, Benjamin L. Miller
The content of this RSS Feed (c) The Royal Society of Chemistry




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Electrochemical determination of paracetamol in a pharmaceutical dose by adsorptive voltammetry with a carbon paste/La2O3 microcomposite

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00442A, Paper
Edgar Nagles, Mario Ceroni, John Hurtado-Murillo, John Hurtado Belalcazar
This paper presents a new application for microcomposites based on carbon paste (CP) and La2O3 (LaOX). This simple and versatile microcomposite (LaOX/CPE) was applied toward the determination of paracetamol (PCM)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Au nanoparticle preconcentration coupled with CE-electrochemiluminescence detection for sensitive analysis of fluoroquinolones in European eel (Anguilla anguilla)

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00264J, Paper
Longhua Guo, Meihua Liu, Yuechun Yin, Lifen Chen, Zhitao Chen, Jing-Jing Liu, Bin Qiu
In this work, a novel method based on gold nanoparticle preconcentration coupled with CE for electrochemiluminescent detection of ciprofloxacin, enrofloxacin, ofloxacin, and norfloxacin in European eels was developed. The addition...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Portable and benchtop Raman spectrometers coupled to cluster analysis to identify quinine sulfate polymorphs in solid dosage forms and antimalarial drug quantification in solution by AuNPs-SERS with MCR-ALS

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00693A, Paper
Sarmento J. Mazivila, Helena I. S. Nogueira, Ricardo N. M. J. Páscoa, David S. M. Ribeiro, João L. M. Santos, João M. M. Leitão, Joaquim C. G. Esteves da Silva
Raman spectrometers coupled to cluster analysis were able to identify two polymorphs of quinine sulfate in solid dosage forms. Gold nanoparticles-surface-enhanced Raman scattering with MCR-ALS was used to antimalarial drug quantification in solution.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Comparison of surfactant-mediated liquid chromatographic modes with sodium dodecyl sulphate for the analysis of basic drugs

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00526F, Paper
N. Pankajkumar-Patel, E. Peris-García, M. J. Ruiz-Angel, M. C. García-Alvarez-Coque
A comprehensive overview of the performance of MLC, HSLC and MELC for the analysis of basic compounds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Droplet image analysis with user-friendly freeware CellProfiler

Anal. Methods, 2020, 12,2287-2294
DOI: 10.1039/D0AY00031K, Technical Note
Simona Bartkova, Marko Vendelin, Immanuel Sanka, Pille Pata, Ott Scheler
We show how to use free open-source CellProfiler for droplet microfluidic image analysis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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LC-MS in combination with DMBA derivatization for sialic acid speciation and distribution analysis in fish tissues

Anal. Methods, 2020, 12,2221-2227
DOI: 10.1039/D0AY00100G, Paper
Junjie Du, Qiwei Zhang, Jianjun Li, Qi Zheng
For sialic acid speciation analysis, DMBA provides superior chromatographic separation efficiency and comparable MS/MS spectra with DMB.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A simple paper-based approach for arsenic determination in water using hydride generation coupled with mercaptosuccinic-acid capped CdTe quantum dots

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00273A, Paper
Oraphan Thepmanee, Kanlaya Prapainop Katewongsa, Obnithi Nooppha, Nuanlaor Ratanawimarnwong, Weena Siangproh, Orawon Chailapakul, Kriangsak Songsrirote
This research aims to develop a simple paper-based device for arsenic detection in water samples where a hydride generation technique coupled with mercaptosuccinic acid-capped CdTe quantum dots (MSA-CdTe QDs) as...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A flower-like Ag coated with molecularly imprinted polymers as surface-enhanced Raman scattering substrate for sensitive and selective detection of glibenclamide

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00575D, Paper
Xiaohui Ren, Xin Li
The flower-like Ag, was formed by nanosheets self-assembly, as SERS active substrate was utilized for preparation of flower-like Ag@molecularly imprinted polymers (MIPs) surface-enhanced Raman scattering (SERS) sensor. Based on the...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Statistical Analysis of Network Data with R [electronic resource] / by Eric D. Kolaczyk, Gábor Csárdi

New York, NY : Springer New York : Imprint: Springer, 2014




with

Classical and Spatial Stochastic Processes [electronic resource] : With Applications to Biology / by Rinaldo B. Schinazi

New York, NY : Springer New York : Imprint: Birkhäuser, 2014




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Input Modeling with Phase-Type Distributions and Markov Models [electronic resource] : Theory and Applications / by Peter Buchholz, Jan Kriege, Iryna Felko

Cham : Springer International Publishing : Imprint: Springer, 2014




with

Modern Optimization with R [electronic resource] / by Paulo Cortez

Cham : Springer International Publishing : Imprint: Springer, 2014




with

A Course on Rough Paths [electronic resource] : With an Introduction to Regularity Structures / by Peter K. Friz, Martin Hairer

Cham : Springer International Publishing : Imprint: Springer, 2014




with

Multistate Analysis of Life Histories with R [electronic resource] / by Frans Willekens

Cham : Springer International Publishing : Imprint: Springer, 2014




with

Introductory Statistical Inference with the Likelihood Function [electronic resource] / by Charles A. Rohde

Cham : Springer International Publishing : Imprint: Springer, 2014




with

Beginning Data Science with R [electronic resource] / by Manas A. Pathak

Cham : Springer International Publishing : Imprint: Springer, 2014




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Fluctuations of Lévy Processes with Applications [electronic resource] : Introductory Lectures / by Andreas E. Kyprianou

Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014




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Programming with Microsoft Visual Basic 2017 / Diane Zak

Zak, Diane, author




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Neural network PC tools : a practical guide / edited by Russell C. Eberhart and Roy W. Dobbins ; with a foreword by Bernard Widrow





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Cantax T1 for New Users with EFILE Webinar 2014

In this 90-minute webinar, we will show you how to get around in the software and what functions are available to make you more productive. Includes an in depth look at Family Coupling, File attachments and the Pathfinder, what they are and how to use them to improve your productivity. This session is intended for those who are new to the Cantax software and those who would like a refresher of all the menu items and their function.

Available Sessions for this Seminar:

December 17, 2014 1:30 PM - 3:00 PM EST
January 16, 2015 1:30 PM - 3:00 PM EST
January 23, 2015 1:30 PM - 3:00 PM EST
January 28, 2015 1:30 PM - 3:00 PM EST




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Performance measures in snow and ice control operations / ICF with Athey Creek Consultants and Vaisala Inc

Barker Library - TE7.N275 no.889




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Reinventing business models: how firms cope with disruption / Henk Volberda, Frans van den Bosch, Kevin Heij

Dewey Library - HD30.28.V66 2018