Cancer took a toll on their relationship.

The reality star is outraged.

NeNe Leakes also admitted she “walked off."

Andy Cohen had to put both of the reality tv stars on mute.

The leak was a HIPPA violation.

The physical integrity of endothelial cells (ECs) lining the blood vessels regulates the inflammatory response. Both innate immunity and inflammatory disorders hinge on the EC-neutrophil interaction. Neutrophil binding, rolling, and migrating along and between ECs is associated with vascular permeability. In this issue of the JCI, Owen-Woods et al. tracked neutrophils in vivo in venules of mouse striated muscle and revealed how endothelial permeability can affect neutrophil trafficking. Strikingly, many neutrophils that migrated between EC junctions were able to rejoin the blood circulation. Further, the chemokine and neutrophil chemoattractant, CXCL1, drove this reverse transendothelial migration (rTEM). This paradigm-shifting study provides a mechanism for distal organ damage as well as an explanation for sepsis-associated acute respiratory distress syndrome.

Increased microvascular permeability to plasma proteins and neutrophil emigration are hallmarks of innate immunity and key features of numerous inflammatory disorders. Although neutrophils can promote microvascular leakage, the impact of vascular permeability on neutrophil trafficking is unknown. Here, through the application of confocal intravital microscopy, we report that vascular permeability–enhancing stimuli caused a significant frequency of neutrophil reverse transendothelial cell migration (rTEM). Furthermore, mice with a selective defect in microvascular permeability enhancement (VEC-Y685F-ki) showed reduced incidence of neutrophil rTEM. Mechanistically, elevated vascular leakage promoted movement of interstitial chemokines into the bloodstream, a response that supported abluminal-to-luminal neutrophil TEM. Through development of an in vivo cell labeling method we provide direct evidence for the systemic dissemination of rTEM neutrophils, and showed them to exhibit an activated phenotype and be capable of trafficking to the lungs where their presence was aligned with regions of vascular injury. Collectively, we demonstrate that increased microvascular leakage reverses the localization of directional cues across venular walls, thus causing neutrophils engaged in diapedesis to reenter the systemic circulation. This cascade of events offers a mechanism to explain how local tissue inflammation and vascular permeability can induce downstream pathological effects in remote organs, most notably in the lungs.

A great many people only experience science fiction by what my mother and millions of others referred to as "monster movies". From Frankenstein to Aliens and beyond, the unknown and the unexplored are often our undoing. Bleak Horizons, edited by Tarl Hoch, is a wonderful collection of 15 stories that mix SF and Horror with various levels of anthropomorphic settings and characters. And, full disclosure, one of those stories is mine. Happily, the mix includes more than just blood thirsty monsters and end of the universe scenarios.

Overall my favorite stories in this anthology are Hardwire, Pentangle, and The Ouroboros Plate. My least favorites are 4/13/2060 and Not Like Us. Below is a short review of all the pieces. I think you should snag a copy, if only to read my favorites and have a taste for this genre. However, I also really enjoyed Carmen Miranda's Ghost Is Haunting Space Station 3 so you have every right to question my taste.

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[Image: “Two images of the same room, one reconstructed from video footage of a bag of chips within the room (top) and the other photographed directly (bottom),” as described by Scientific American. Images courtesy Jeong Joon Park.] “Researchers have now found that by filming a brief video clip of a shiny item, they can use … Continue reading "Every Reflection A Leak"

LeakyMug special! Andrew Sims of MuggleCast and Melissa Anelli of PotterCast just saw the special extended footage of the Harry Potter and the Deathly Hallows films at San Diego Comic Con 2010, and interviewed Tom Felton about the entire experience, and meet here in this special recording to run down all the details for you.

Episode 223 — LeakyMug from Comic Con; Deathly Hallows Footage

Find the latest episode and explore PotterCast interviews, discussions and more at PotterCast.com

Visit the-leaky-cauldron.org for the latest and greatest from Harry Potter's Wizard World.

This episode features an interview with Starkids Joe, Brian, and Dylan, talking about everything from their new upcoming Musical, Starship, as well as their big performance at this Summer's LeakyCon!

Episode 230 — Starkid Potter is Going to LeakyCon!

Find the latest episode and explore PotterCast interviews, discussions and more at PotterCast.com

Visit the-leaky-cauldron.org for the latest and greatest from Harry Potter's Wizard World.

At long last - enjoy our post Deathly Hallows Part 2 episode of PotterCast recorded live at LeakyCon FEATURING EVANNA LYNCH (Luna Lovegood) and SCARLETT BYRNE (Pansy Parkinson) and many of YOUR questions about the film!

Episode 242 — Deathly Hallows Part 2 Live At LeakyCon!

Find the latest episode and explore PotterCast interviews, discussions and more at PotterCast.com

Visit the-leaky-cauldron.org for the latest and greatest from Harry Potter's Wizard World.

We are back and we are live from the last day of LeakyCon 2014! Talk about WWoHP, Fantastic Beasts, live Canon Conclundrums AND MORE await... also welcome to special guest Mark Oshiro!

Remember LeakyMugs? We do! LIVE from GeekyCon 2016, PotterCast and MuggleCast discuss their reactions to Harry Potter and the Cursed Child, fresh off reading it!

Witches, wizards, warlocks and magical creatures of LeakyCon 2016 join the cast of PotterCast in Los Angeles, California for an emotional and far reaching discussion on the current state of affairs in J.K. Rowling's Wizarding World and what its future holds for us all!

Episode 262 — LeakyCon 2016!

Find the latest episode and explore PotterCast interviews, discussions and more at PotterCast.com

Visit the-leaky-cauldron.org for the latest and greatest from Harry Potter's Wizard World.

PotterCast 273 is the first of our episodes from LeakyCon Dublin! And this time we have Evanna Lynch (Luna Lovegood), Katie Leung (Cho Chang), Alfie Enoch (Dean Thomas), and Afshan Azad (Padma Patil), here to tell us all about life as the Harry Potter films' Dumbledore's Army. Great stories from their time filming - a must-listen!

PotterCast 278 brings back the news roundups! Emma from The Leaky Cauldron joins us to keep us updated about the latest goings on in Harry Potter news (with all the info on the newest Harry Potter video game, the Cursed Child Broadway premiere, and Dan Fogler's podcast...). 

We also break down Ch. 6 of Sorcerer's Stone (and it's now John's job to summarize each chapter forever). Also in this episode: a deep dive on chocolate frog cards (is this the wizarding world's version of Facebook messenger?), what do wizards wear under their clothes?, MORE on wizarding clothing (when will we stop?), and Dudley vs. fat shaming.

Happy holidays! This week we are going back to LeakyCon in Dallas, where The Ringer's Mallory Rubin and Jason Concepcion interviewed Alison Sudol about Queenie Goldstein, writing, creation, and more. This was conducted BEFORE CoG came out in theaters, so maybe now is a great time to revisit everything we heard. 

We'll be presenting more of these interviews between now and the day we return in the second week of January! Enoy! And make sure to check out Mal and Jason's podcast, Binge Mode: Harry Potter — they truly are some of the best Potter podcasters in history.

Live from LeakyCon 2019: Dallas – Melissa interviews Tom Felton (Draco Malfoy) and he tells stories from filming, discusses the passion of fandom, and answers audience questions!

Remember – LeakyCon is coming! Join us in Boston, MA from October 11-13th for our TENTH anniversary! Get your tickets now.

PotterCast is a Mischief Media podcast! Check out all we have to offer. This episode was hosted by Melissa Anelli, John Noe, and Frak Fraco III, produced by Adam Molina, and associate produced by Kylie Madden.

LIVE FROM LEAKYCON: PotterCast's Spotlight with Dan Fogler!

In this episode, we talk with Dan Fogler about how he approached Jacob's characterization in the Fantastic Beasts films, what it's like to film knowing the magical creatures will be added in post-production, Jacob's complicated relationship with Queen, and more! 

There are three games in this episode! We recommend putting yourself into the mode of a contestant as you listen to the first.

Remember!

1. Visit Mischief Merch to purchase this limited edition PotterCast: After All This Time shirt.
2. Don’t forget that we have a Patreon where you can get extra (sorting-related!) content!
3. Check out our new sponsor, Shaker and Spoon

DigitalOcean, one of the biggest modern web hosting platforms, recently hit with a concerning data leak incident that exposed some of its customers' data to unknown and unauthorized third parties. Though the hosting company has not yet publicly released a statement, it did has started warning affected customers of the scope of the breach via an email. According to the breach notification

By Luis Prada  Published: May 07th, 2020 

An American woman goes to the police in Las Vegas. She claims she has been raped by an athlete: global football star Cristiano Ronaldo. What really happened has never been resolved because lawyers settled the case with a payment of $375,000 by the Real Madrid star. By SPIEGEL Staff

Rui Pinto is the whistleblower behind Football Leaks and has been in jail in Portugal for months. In an interview, his lawyer William Bourdon talks about how his client is doing and what he is doing to get Pinto out of prison.

Brendan Leipsic talked his way out of a job.

Laois hurling manager Eddie Brennan believes a resumption of GAA matches faces numerous challenges amid the Covid-19 pandemic, with a vaccine the only surefire measure to allay concerns of players and public alike.

The document has been in the works for some time, but reports say the White House tried to suppress it.

Brendan Leipsic talked his way out of a job.

Piers Morgan believes the Premier League and EFL campaigns should be voided because of the COVID-19 outbreak.

UK HOLIDAYMAKERS have been urged not to book a summer holiday abroad following the Government's leaked airport quarantine plan, according to a leading aviation expert.

UK HOLIDAYMAKERS have been urged not to book a summer holiday abroad following the Government's leaked airport quarantine plan, according to a leading aviation expert.

Conventions, conferences and trade shows cling to calendar spots with cautious optimism after the coronavirus pandemic caused tourism to nosedive.

Simon Property Group plans to reopen on Saturday Indiana malls shuttered during the coronavirus pandemic, according to a leaked internal memo.

strataconf: StrataWeek: Wireless body networks bring humans into Internet of Things http://t.co/vRgkRtTTKe Pills & tattoo authenticators & NSA leaks

With the working class resorting to online vouchers for groceries and the poor eating less bread than before, is it not impractical for the president to expect ordinary citizens to tighten their belts when MPs, Ministers and government officials' well-fed bellies belie the trouble the economy is in?

The leak exposed millions of records with full names, emails, user conversations, payment logs, and IP addresses dating back to March.

The big story of the week is Wikileaks' CIA data dump, and we sandwich that topic between Apple's upcoming event and Nintendo Switch hardware issues. Lewis Painter kicks things off with Apple's (fingers crossed) late March event where we hope to see iPads, iMacs and get our six monthly fix of Jony Ive product videos. Then (13 minutes) Tamlin Magee tackles Vault 7 and the CIA's apparent ability to take control of iPhones and TVs, bypassing encryption. Will continuous leaks change anything? Finally (26 minutes) Dom Preston talks about his time over the last few weeks playing Zelda on the Nintendo Switch and why we should be a bit concerned about dodgy controllers.  

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Join Miriam Harris, David Price and Henry Burrell as they dissect the weird internal memo row at Google. Was a male engineer genuinely trying to help Google and make a point about the company being too Left, or is he just an arsehole? Then we describe the iPhone 8 dummy we received this week (take a look at it here: https://www.youtube.com/watch?v=PRNIwh61j_E ) and the revelations that came from the Homepod firmware leak. We also debate the usefulness of an LTE Apple Watch and try to make puns work. Magic.  

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