The Delaware Department of Agriculture is urging farmers to participate in the two major mid-year surveys, the June Agricultural Survey and the June Area Survey, conducted by USDA’s National Agricultural Statistics Service (NASS). NASS will survey nearly 400 farmers across Delaware to determine crop production and supply levels in 2017. “As an $8 billion industry, agriculture plays a major role in Delaware’s economy,” said Secretary of Agriculture Michael Scuse. “The information that our farmers provide is critical to helping everyone – from fellow farmers to lawmakers to extension professionals – make decisions that will impact our industry. It is critical that NASS has the most accurate data, so I urge Delaware farmers to participate in the June Surveys.”

Delaware Secretary of Agriculture Michael Scuse is reminding farmers to complete the small grain production survey that has been sent out to nearly 300 producers by the USDA’s National Agricultural Statistics Service (NASS). The agency is taking a comprehensive look into the 2017 production and supply of small grains, which include wheat, oats, barley, and rye. 

During the next several weeks, U.S. Department of Agriculture’s National Agricultural Statistics Service (NASS) will conduct two major mid-year surveys, the June Agricultural Survey and the June Area Survey. The agency will contact around 350 producers across Delaware to determine crop acreage and stock levels as of June 1, 2018.

SHORT messaging services (SMS) on mobile phones will be restored in Jammu and Kashmir Tuesday midnight, the 150th day since the government suspended it in the erstwhile state.

The Federal Communications Commission voted on Thursday to regulate broadband Internet service...

Hi All, Here's another great new feature that I've found very helpful... Broadband SPICE is a new tool for S-parameter simulation in Spectre RF. In the MMSIM13.1.1 ( MMSIM13.1 USR1) release (now available on http://downloads.cadence.com), a...(read more)

On 16 October 2019, the FCA published their feedback statement FS19/6 on Climate Change and Green Finance[1]. This feedback statement summarises the responses from stakeholders to the Discussion Paper (DP18/8) on Climate Change and Green Finance[2] ...

ISLAMABAD: The Universal Service Fund awarded contract worth PKR 588 million to Telenor Pakistan for providing hi-speed broadband in Sanghar Lot .The Federal Minister IT& Telecom, Syed Amin ul...

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CES 2020, LAS VEGAS – JANUARY 6, 2020 – Movie lovers, listen up. The latest addition to JBL’s popular Bar Series brings the audio experience of a movie theater to your living room. The JBL Bar 9.1 creates true wireless surround sound with crowd-pleasing...

Een gestroomlijnd model, krachtige bas en nog intenser geluid: JBL tilt home entertainment naar een hoger plan. Op IFA worden vandaag drie splinternieuwe producten gelanceerd: een compacte alles-in-één oplossing, een kamervullende surround-sound en een diepe bas Bar. Voor ieder wat wils in de nieuwe Soundbar serie.

Slimmer, punchier bass and more immersive sound; JBL has taken home entertainment to the next level. With three brand new products launching today at IFA including a compact, all-in-one solution, a deep bass beauty and a surround-sound room-filler, there is something for everyone in JBL’s new soundbar range.

Slimmer, punchier bass and more immersive sound; JBL has taken home entertainment to the next level. With three brand new products launching today at IFA including a compact, all-in-one solution, a deep bass beauty and a surround-sound room-filler, there is something for everyone in JBL’s new soundbar range.

ABSTRACT

Two-component signaling systems (TCSs) function to detect environmental cues and transduce this information into a change in transcription. In its simplest form, TCS-dependent regulation of transcription entails phosphoryl-transfer from a sensory histidine kinase to its cognate DNA-binding receiver protein. However, in certain cases, auxiliary proteins may modulate TCSs in response to secondary environmental cues. Caulobacter crescentus FixT is one such auxiliary regulator. FixT is composed of a single receiver domain and functions as a feedback inhibitor of the FixL-FixJ (FixLJ) TCS, which regulates the transcription of genes involved in adaptation to microaerobiosis. We sought to define the impact of fixT on Caulobacter cell physiology and to understand the molecular mechanism by which FixT represses FixLJ signaling. fixT deletion results in excess production of porphyrins and premature entry into stationary phase, demonstrating the importance of feedback inhibition of the FixLJ signaling system. Although FixT is a receiver domain, it does not affect dephosphorylation of the oxygen sensor kinase FixL or phosphoryl-transfer from FixL to its cognate receiver FixJ. Rather, FixT represses FixLJ signaling by inhibiting the FixL autophosphorylation reaction. We have further identified a 4-cysteine motif in Caulobacter FixT that binds an Fe-S cluster and protects the protein from degradation by the Lon protease. Our data support a model in which the oxidation of this Fe-S cluster promotes the degradation of FixT in vivo. This proteolytic mechanism facilitates clearance of the FixT feedback inhibitor from the cell under normoxia and resets the FixLJ system for a future microaerobic signaling event.

IMPORTANCE Two-component signal transduction systems (TCSs) are broadly conserved in the bacterial kingdom and generally contain two molecular components, a sensor histidine kinase and a receiver protein. Sensor histidine kinases alter their phosphorylation state in direct response to a physical or chemical cue, whereas receiver proteins "receive" the phosphoryl group from the kinase to regulate a change in cell physiology. We have discovered that a single-domain receiver protein, FixT, binds an Fe-S cluster and controls Caulobacter heme homeostasis though its function as a negative-feedback regulator of the oxygen sensor kinase FixL. We provide evidence that the Fe-S cluster protects FixT from Lon-dependent proteolysis in the cell and endows FixT with the ability to function as a second, autonomous oxygen/redox sensor in the FixL-FixJ signaling pathway. This study introduces a novel mechanism of regulated TCS feedback control by an Fe-S-binding receiver domain.

Peripheral somatosensory input is modulated in the dorsal spinal cord by a network of excitatory and inhibitory interneurons. PTF1A is a transcription factor essential in dorsal neural tube progenitors for specification of these inhibitory neurons. Thus, mechanisms regulating Ptf1a expression are key for generating neuronal circuits underlying somatosensory behaviors. Mutations targeted to distinct cis-regulatory elements for Ptf1a in mice, tested the in vivo contribution of each element individually and in combination. Mutations in an autoregulatory enhancer resulted in reduced levels of PTF1A, and reduced numbers of specific dorsal spinal cord inhibitory neurons, particularly those expressing Pdyn and Gal. Although these mutants survive postnatally, at ~3–5 wk they elicit a severe scratching phenotype. Behaviorally, the mutants have increased sensitivity to itch, but acute sensitivity to other sensory stimuli such as mechanical or thermal pain is unaffected. We demonstrate a requirement for positive transcriptional autoregulatory feedback to attain the level of the neuronal specification factor PTF1A necessary for generating correctly balanced neuronal circuits.

Sonos has been busy these past few months.

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Some people answer some questions. Chris tries to give us a Just Cause for why he attached that cow to that helicopter. Alice gets Fruity...

Virgin Media customers are still complaining about issues with their broadband despite the provider saying the issue has been fixed.

Pai’s “baffling” report ignores broadband gaps and high prices, Democrats say.

Small ISPs want investigation as Frontier tries to block FCC funding for rivals.

Most of us get high-speed internet via a wired connection. But not everyone has access, like in rural areas. 5G could broaden those broadband options.

Experts react to role of distributors, legislation in opioid crisis

Experts discuss recent cancellation of first-in-class drug

Kevin Howard, former chief financial officer and vice president of finance for Enron Broadband Services (EBS), Enron’s failed telecommunications business, pleaded guilty today to falsifying books and records.

Joseph Hirko, former co-chief executive officer of Enron Broadband Services (EBS), Enron’s failed telecommunications business, was sentenced today to 16 months in prison.

"As we have seen repeatedly – most clearly on September 11th and in the aftermath of Hurricane Katrina – in times of crisis and emergency, law enforcement officers and first responders must be able to communicate quickly, across all jurisdictions. And as national security and public safety threats have continued to grow and to evolve, the need to bring public safety communications into the 21st century has never been greater."

For the vast majority of us, broadband has become so commonplace in our professional, personal, and social lives that we rarely think about how much we depend on it. Yet without broadband, our lives would be radically upended: Our work days would look different, we would spend our leisure time differently, and even our personal…

The National Broadband Plan should be carefully designed so as not to reduce the investment in broadband technologies, which have averaged $30 billion per year since 2005, say Robert W. Crandall and Hal J. Singer. To do otherwise, they say, would risk a reduction in the incentives for investment in the nation’s broadband infrastructure and the hundreds of thousands of jobs that such investment supports.

"Chatangora" — that's what Simpsonville, South Carolina-based business Catty Shack Creations is calling "cat hair yarn" — used to create affordable, one-of-a-kind handbags from Persian and Angora cat hair. Professional groomer Danelle

The real life romance sparked while making a merry romp of this endangered species protection success story could be the sequel!

The easiest way to mix up an outfit is with accessories. Fortunately, Daily Candy recently highlighted 8 green fashion handbags for spring 2010. From vintage handbags with a hand-painted twist to multifunctional back-packs with

Add some pizzazz to your hairdo with these fun, colorful accessories, all made in USA.

Representational picture

While you are upgrading your wardrobe with Summer staples like floral dresses, shorts and tank tops, don’t forget to amp up your style with the perfect handbag. From carry-it-all oversized tote bags to stylish circular bags that are the rage, refresh your wardrobe with the top handbags for the season with tips from Narendra Kumar, Creative Director, Amazon Fashion!

Fringed and tasseled
Fringes and tassels are one of the key trends this season. A leather sling back with flirty fringes makes for the perfect daytime bag but be sure to incorporate just the right amount. For a bohemian look carry a fringe bag with a floral dress. Balance it out by keeping the rest of your outfit simple and straight with basic accessories.

Bucket bags
The bucket bag is an absolute must have in your wardrobe. While the structure is more casual, with minimalist designs and neutral hues, these look sophisticated and chic. Open bucket bags have a thick strap on top whereas closed bucket bags have drawstrings around the top.

Circular bags
Here is a refreshing new trend for Spring-Summer. These circular shaped bags will add a fun and distinctive touch to your whole look. Go for sleek, elegant designs in solid colors. If you are looking for something more casual, get a textured leather bag or denim with patchwork. These are quite small but come in a huge variety of styles.

Oversized tote and hobo
Oversized totes and hobos are the best bags to carry it all! These can easily transition from your work wear to a casual everyday bag. While neutrals work best with formals, a bright oversized bag is all you need for a day at the beach. However, since oversized bags tend to look bulky or slouchy, get a structured one.

Mini bags
Along with oversized bags, mini bags have also become a popular choice. Although these are very small, it can be a statement piece. Mini bags come with cute detailing like bows or buckles in boxy shapes. Pick a pastel colored mini bag with a top handle to carry your basic essentials.

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13/03/2020

Oil is doing something that is even making Market veterans shake their heads in wonder. After shedding more than 300 per cent or $56 a barrel in one single day on Monday, the West Texas Intermediate (WTI) crude for May delivery gained some ground early on Tuesday, recovering 103 per cent to come back in the positive zone at $1.35 a barrel.

But analysts expect that bloodbath in US oil market may continue well into Tuesday when May future contracts are expiring and traders still left with long positions facing actual delivery of oil may look to liquidate their stock even if they have to pay to do this. In simple terms this means that traders do not want to store crude by taking actual delivery for May and incur cost while not finding any buyers in the absence of demand that has also shrunk sharply by more than a third in Covid-19 pandemic.

"We could again see price of oil in US going into the negative zone on Tuesday. But this could be a lot less sharper than what was witnessed on Monday," said an oil sector analyst asking not to be named.

He said that lower oil prices bore good for India but how much oil companies can gain from US fall is uncertain as the Indian oil companies are not very active in the US markets and trade very small quantities in the spot market. Still some of this oil could be contracted if freight arrangements are worked out on time.

While US oil has shown significant fall, Brent has maintained a fairly steady path. The benchmark Brent oil is still hovering at $ 25 a barrel. The US WTI for June delivery is still keeping its heads up at over $ 20 a barrel. But it would be seen if Covid-19 situation improves in coming days and demand picks up. Otherwise, June oil futures can go the May way.

The decline of oil prices comes despite the recent output cut agreement between the Organisation of the Petroleum Exporting Countries (OPEC) and its allies.

There were hopes that agreement would stabilise oil prices, but with the Covid-19 pandemic continuing, there has been a large slip in demand that is not letting a pick-up in oil prices.

The current market is oversupplied on shrinking demand, creating a situation of free fall for crude.

The price of oil has now reached a point that it is increasingly becoming difficult for higher cost producers to remain in operation and rather look at declaring bankruptcy.

A lot of US shale producers are in deep trouble and analysts expect that low oil price for few more months will result in a spate of bankruptcies in the US.

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The OECD has requested stakeholders' input on the dispute resolution processes in place in Andorra, Anguilla, Bahamas, Bermuda, the British Virgin Islands, the Cayman Islands, the Faroe Islands, Macau (China), Morocco, and Tunisia.

About 60 percent of the region’s people are employed by the agricultural sector, which depends almost entirely on irrigation.

Switzerland tops for the first time the OECD fixed broadband ranking, with 39.9 subscribers per 100 inhabitants, followed closely by the Netherlands (39.1) and Denmark (37.9). The OECD average is 25.6, according to new OECD statistics.

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The OECD has today released its standardised IT-format for providing structured feedback on exchanged Common Reporting Standard information – the CRS Status Message XML Schema – as well as the related User Guide.