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[ASAP] Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin–MLL Interaction with Strong <italic toggle="yes">In Vivo</italic> Antitumor Activity

By feedproxy.google.com
Published On :: Mon, 27 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00547

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[ASAP] Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies

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Published On :: Wed, 29 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00202

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[ASAP] Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1

By feedproxy.google.com
Published On :: Thu, 30 Apr 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00101

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[ASAP] Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity

By feedproxy.google.com
Published On :: Wed, 06 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00245

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[ASAP] Optimization of Potent ATAD2 and CECR2 Bromodomain Inhibitors with an Atypical Binding Mode

By feedproxy.google.com
Published On :: Wed, 06 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00021

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[ASAP] Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue

By feedproxy.google.com
Published On :: Thu, 07 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00337

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[ASAP] Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to <italic toggle="yes">In Vivo</italic> Studies

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Published On :: Thu, 07 May 2020 04:00:00 GMT

Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c00431

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[ASAP] Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies

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Published On :: Thu, 02 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00075

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[ASAP] Synthesis of Novel G Factor or Chloroquine-Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity

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Published On :: Thu, 02 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.9b00669

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[ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents

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Published On :: Wed, 08 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.9b00639

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[ASAP] Discovery of BMS-986251: A Clinically Viable, Potent, and Selective ROR?t Inverse Agonist

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Published On :: Fri, 10 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00063

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[ASAP] Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents

By feedproxy.google.com
Published On :: Fri, 10 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00129

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[ASAP] Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors

By feedproxy.google.com
Published On :: Mon, 13 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.9b00438

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[ASAP] Potential Cancer Treatment by Agonists of the Stimulator of Interferon Genes

By feedproxy.google.com
Published On :: Mon, 13 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00117

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[ASAP] Discovery of a Potent Dual Inhibitor of Wild-Type and Mutant Respiratory Syncytial Virus Fusion Proteins

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Published On :: Wed, 15 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00008

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[ASAP] Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor

By feedproxy.google.com
Published On :: Mon, 27 Apr 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00155

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[ASAP] Discovery of RO7185876, a Highly Potent ?-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer’s Disease

By feedproxy.google.com
Published On :: Fri, 01 May 2020 04:00:00 GMT

ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.0c00109

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Unlock Your Team’s Potential With Teamstack

By www.webdesignerdepot.com
Published On :: Tue, 21 Apr 2020 10:45:38 +0000

Teamstack is a password manager for your whole team. Running in the cloud it allows you to manage your tools and resources, and seamlessly scale your teams’ access, from a single, easy-to-use control panel. Teamstack is powerful, and secure with multi-factor authentication, single sign-in, SAML and form-based authentication. It works with desktop and mobile apps, […]

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2019 Hawaii Book & Music Festival: UH Press Tent and Author Events

By uhpress.wordpress.com
Published On :: Thu, 02 May 2019 19:19:58 +0000

The 14th annual Hawai‘i Book and Music Festival happens this weekend, 10 a.m. to 5 p.m. each day, and UH Press will once again be there! Come to our tent alongside Honolulu Hale, near the Kristi Yamaguchi Keiki Reading Corner, and be among the first to see our newest titles. Also attend several presentations by […]

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During a Pandemic, Behavioral Health Demands Attention and Creativity

By www.mathematica.org
Published On :: Fri, 24 Apr 2020 13:42:00 Z

For those of us who devote our lives to improving behavioral health care, the critical health care priorities of the COVID-19 pandemic raise concerns about increased unmet mental health and substance use service needs.

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I William Zartman: a pioneer in conflict management and area studies: essays on contention and governance / I. William Zartman ; with a foreword by Francis Deng and a preface by Ellen Laipson

By library.mit.edu
Published On :: Sun, 7 Jul 2019 09:21:52 EDT

Online Resource

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Roger Sandall's films and contemporary anthropology: explorations in the aesthetic, the existential, and the possible / Lorraine Mortimer

By library.mit.edu
Published On :: Sun, 26 Jan 2020 06:46:16 EST

Dewey Library - PN1998.3.S2517 M67 2019

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Nonfiction sound and story for film and video: a practical guide for filmmakers and digital content creators / Amy DeLouise & Cheryl Ottenritter

By library.mit.edu
Published On :: Sun, 15 Mar 2020 06:46:24 EDT

Dewey Library - PN1995.9.P7 D45 2020

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An integrated approach for content extraction, word segmentation and information presentation from Thai websites / Wigrai Thanadechteemapat

By prospero.murdoch.edu.au
Published On ::

Thanadechteemapat, Wigrai

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An integrated mobile content recommendation system / Worapat Paireekreng

By prospero.murdoch.edu.au
Published On ::

Paireekreng, Worapat

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Participate : designing with user-generated content / Helen Armstrong and Zvezdana Stojmirovic

By prospero.murdoch.edu.au
Published On ::

Armstrong, Helen, 1971-

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Content strategy for the Web / Kristina Halvorson, Melissa Rach ; foreword by Sarah Cancilla, Facebook

By prospero.murdoch.edu.au
Published On ::

Halvorson, Kristina

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Ancient and medieval theories of intentionality / edited by Dominik Perler

By prospero.murdoch.edu.au
Published On ::

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Neuroexistentialism : meaning, morals, and purpose in the age of neuroscience / edited by Gregg D. Caruso and Owen Flanagan

By prospero.murdoch.edu.au
Published On ::

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Online hate and harmful content: cross-national perspectives / Teo Keipi, Matti Näsi, Atte Oksanen, and Pekka Räsänen

By library.mit.edu
Published On :: Sun, 22 Mar 2020 07:44:49 EDT

Online Resource

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Anscombe's Intention: a Guide.

By library.mit.edu
Published On :: Sun, 8 Mar 2020 06:48:05 EDT

Online Resource

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Phenomenology and Existentialism edited by Edward N. Lee and Maurice Mandelbaum

By library.mit.edu
Published On :: Sun, 8 Mar 2020 06:48:05 EDT

Online Resource

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Reasons in action: a reductionist account of intentional action / Ingmar Persson

By library.mit.edu
Published On :: Sun, 22 Mar 2020 06:38:46 EDT

Dewey Library - B105.A35 P47 2019

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Intention, character, and double effect / Lawrence Masek

By library.mit.edu
Published On :: Sun, 26 Apr 2020 07:06:33 EDT

Dewey Library - BJ1500.D68 M37 2018

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Effing the ineffable: existential mumblings at the limits of language / Wesley J. Wildman

By library.mit.edu
Published On :: Sun, 26 Apr 2020 07:06:33 EDT

Hayden Library - BD453.W55 2018

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The world-directedness of emotional feeling: on affect and intentionality / Jean Moritz Müller

By library.mit.edu
Published On :: Sun, 3 May 2020 07:23:24 EDT

Dewey Library - B815.M2 M85 2019

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Potentiating anti-cancer chemotherapeutics and antimicrobials via sugar-mediated strategies

By pubs.rsc.org
Published On ::

Mol. Syst. Des. Eng., 2020, Advance Article
DOI: 10.1039/C9ME00175A, Minireview

Sneha Sree Mullapudi, Debirupa Mitra, Min Li, En-Tang Kang, Edmund Chiong, Koon Gee Neoh
This article reviews the design considerations behind sugar-mediated strategies for potentiating the efficacy of drugs/photosensitizers in cancer treatment, and antimicrobials.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

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Discovery of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing 4-oxo-pyridazinone moiety as potential c-Met kinase inhibitors

By feeds.rsc.org
Published On ::

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00575D, Paper

Binliang Zhang, Xiaobo Liu, Hehua Xiong, Qian Zhang, Xin Sun, Zunhua Yang, Shan Xu, Pengwu Zheng, Wufu Zhu
Two series of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing 4-oxo-pyridazinone moiety (compounds 21a-l and 22a-l) were designed and evaluated for the IC50 values against three cancer cell lines (A549, MCF-7 and Hela) and...
The content of this RSS Feed (c) The Royal Society of Chemistry

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POM-based dyes featured rigidified bithiophene π linkers: Potential high-efficient dyes for dye-sensitized solar cells

By feeds.rsc.org
Published On ::

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01150A, Paper

Yu Gao, Li-Kai Yan, Wei Guan, Yanhong Xu
A series of POM-based dyes with triphenylamine electron donor group, cyanoacrylic acid electron acceptor group and different π linkers of thiophene derivatives are systematically investigated to analyze the influence of...
The content of this RSS Feed (c) The Royal Society of Chemistry

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Securing persistent environment variables using ZEIT Now

By feedproxy.google.com
Published On :: Tue, 03 Sep 2019 00:00:00 +0000

I’m a big fan of ZEIT Now1 as an application hosting provider. The way the service abstracts all of the cloud computing details and allows teams to focus on building and deploying web applications is fantastic. That said, I had a lot of trouble setting up secure environment variables for my first application to use....

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[ASAP] Potentiation of Antibiotics against Gram-Negative Bacteria by Polymyxin B Analogue SPR741 from Unique Perturbation of the Outer Membrane

By dx.doi.org
Published On :: Wed, 23 Oct 2019 04:00:00 GMT

ACS Infectious Diseases

DOI: 10.1021/acsinfecdis.9b00159

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[ASAP] Dilipid Ultrashort Tetrabasic Peptidomimetics Potentiate Novobiocin and Rifampicin Against Multidrug-Resistant Gram-Negative Bacteria

By dx.doi.org
Published On :: Thu, 07 May 2020 04:00:00 GMT

ACS Infectious Diseases

DOI: 10.1021/acsinfecdis.0c00017

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Attracting attention : promotion and marketing for tourism attractions / Andi Stein

By prospero.murdoch.edu.au
Published On ::

Stein, Andi, 1960-

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The contentious and advisory jurisdiction of the International Tribunal for the Law of the Sea / by Miguel García García-Revillo ; foreword by Tullio Treves, Rafael Casado

By prospero.murdoch.edu.au
Published On ::

García-Revillo, Miguel García, author

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Patent law in Australia / Colin Bodkin

By prospero.murdoch.edu.au
Published On ::

Bodkin, Colin (Colin Lewis), 1947-

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Integrating water systems: proceedings of the tenth international conference on computing and control in the water industry 2009 / edited by Joby Boxall and?edo Maksimovi?

By library.mit.edu
Published On :: Sun, 22 Dec 2019 07:46:07 EST

Online Resource

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Petroleum basins and hydrocarbon potential of the Andes of Peru and Bolivia / edited by G. Zamora, K. R. McClay, and V. A. Ramos

By library.mit.edu
Published On :: Sun, 12 Jan 2020 08:09:51 EST

Hayden Library - TN873.P4 P48 2018

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Kin of other victims flock to village to catch VIP attention

By indianexpress.com
Published On :: Mon, 02 Jun 2014 20:02:02 +0000

DO NOT USE Uttar Pradesh
India

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Potentiation of polycyclic aromatic hydrocarbon uptake in zebrafish embryos by nanoplastics

By pubs.rsc.org
Published On ::

Environ. Sci.: Nano, 2020, Advance Article
DOI: 10.1039/D0EN00163E, Paper

Yueyang Zhang, Greg G. Goss
The presence of microplastics in the environment and their potential effects on the health of organisms are a subject of great concern.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

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The effect of deuteration-levels in solution and temperature on the segregation coefficient of deuterium content in rapid-grown K(DxH1-x)2PO4 crystals using Raman spectroscopy

By feeds.rsc.org
Published On ::

CrystEngComm, 2020, Accepted Manuscript
DOI: 10.1039/D0CE00386G, Paper

Jinxin Huang, Zongqi Wang, Bing Teng, Hong Liu, Xixi Zheng, Shaohua Ji
A series of K(D_xH_1-x)₂PO₄ (DKDP) crystals with different saturating temperature and deuteration levels were grown by point-seed rapid growth method. The correlation between deuterium segregation coefficient and temperature and deuterium...
The content of this RSS Feed (c) The Royal Society of Chemistry