Online Resource

Online Resource

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Hayden Library - RG761.W65 2018

Mathematica has released positive evaluation findings from Year 2 of the Million Hearts® model, just in time for American Heart Month this February.

Dewey Library - JC599.D44 T75 2020

Dewey Library - UA23.O347 2019

Faure, Michael (Michael G.), author

Bloomberg's risk map signals where danger lurks

Lowering low-density lipoprotein cholesterol (LDL-C) levels remains a mainstay of cardiovascular disease prevention, but gaps in treatment remain, even in persons with hypercholesterolemia and greatly elevated LDL-C levels. Although well-described gene variants in the apolipoprotein B (APOB), low-density lipoprotein receptor (LDLR), and proprotein convertase subtilisin/kexin type 9 (PCSK9) genes explain small but important fractions of monogenic hypercholesterolemia, recent attention has turned to prognostication of cardiovascular disease using polygenic risk scores (PRS) that incorporate common genetic variants derived from large-scale genome-wide association studies of lipid subfractions. Earlier PRS considered only variants with genome-wide significance, and newer studies have focused on methods that better capture the variance conferred by millions of variants, suggesting an ability to identify risk equivalent to monogenic mutations. There remains a gap in evidence from prospective observational studies or treatment trials regarding the appropriate placement of PRS in risk assessment and lipid treatment decisions relative to information on rare monogenic gene variants, particularly in multiethnic populations.

This cohort study uses the UK Biobank cohort data to compare the association of monogenic vs polygenic hypercholesterolemia with the risk of atherosclerotic cardiovascular disease among individuals with comparable levels of low-density lipoprotein cholesterol.

State health officials are planning extensive tests

Briskin, Alan, 1954-

Godfrey, Paul C., author

Bhansali, Vineer

McGinn, Jeffrey

DeMarco, Tom, author

Interview with Nora Pashayan, BSc MSc MSt MD PhD FFPH, author of Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Screening for Breast Cancer: A Life-Table Model

Interview with Mollie E. Barnard, ScD, and Shelley Tworoger, PhD, authors of Association of Analgesic Use With Risk of Ovarian Cancer in the Nurses’ Health Studies, and Andrew T. Chan, MD, MPH, author of Association Between Aspirin Use and Risk of Hepatocellular Carcinoma

Interview with Caroline C. Kim, MD, author of Risk of Subsequent Cutaneous Melanoma in Moderately Dysplastic Nevi Excisionally Biopsied but With Positive Histologic Margins

Interview with Julia Baudry, PhD, author of Association of Frequency of Organic Food Consumption With Cancer Risk: Findings From the NutriNet-Santé Prospective Cohort Study, and Jorge E. Chavarro, MD, ScD, author of Organic Foods for Cancer Prevention—Worth the Investment?

Interview with Kelly Wade, MD, PhD, MSCE, and Graham Quinn, MD, MSCE, authors of Factors in Premature Infants Associated With Low Risk of Developing Retinopathy of Prematurity

Interview with Anthony D'Amico, MD, PhD, author of Surgery vs Radiotherapy in the Management of Biopsy Gleason Score 9-10 Prostate Cancer and the Risk of Mortality

Interview with Andrew J. Dannenberg, MD, author of Association of Body Fat and Risk of Breast Cancer in Postmenopausal Women With Normal Body Mass Index: A Secondary Analysis of a Randomized Clinical Trial and Observational Study

Interview with Meghan Miller, PhD, author of Sibling Recurrence Risk and Cross-aggregation of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder

Interview with Megan H. Noe, MD, MPH, MSCE, author of Development and Validation of a Risk Prediction Model for In-Hospital Mortality Among Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis—ABCD-10

Interview with David Urbach, author of The Role of Disease Label in Patient Perceptions and Treatment Decisions in the Setting of Low-Risk Malignant Neoplasms

Interview with J. Donald Easton, jdeaston, author of Risk for Major Hemorrhages in Patients Receiving Clopidogrel and Aspirin Compared With Aspirin Alone After Transient Ischemic Attack or Minor Ischemic Stroke: A Secondary Analysis of the POINT Randomized Clinical Trial

Interview with Donald A. Redelmeier, MD, FRCPC, MSHSR, FACP, author of Association Between Statin Use and Risk of Dementia After a Concussion

Interview with Andreas Heinz, Prof. , MD, PhD, author of Risk of Psychosis Among Refugees: A Systematic Review and Meta-analysis

Interview with Shelagh B. Coutts, MD, FRCPC, author of Rate and Prognosis of Brain Ischemia in Patients With Lower-Risk Transient or Persistent Minor Neurologic Events

Interview with Michael J. Reardon, MD, Martin B. Leon, MD, and Patrick T. O'Gara, MD, authors of Transcatheter Aortic Valve Replacement for Patients at Low Surgical Risk—Selective or Ubiquitous?

Interview with Amir Sariaslan, PhD, author of Risk of Subjection to Violence and Perpetration of Violence in Persons With Psychiatric Disorders in Sweden

Interview with Christina Vandenbroucke-Grauls, MD, PhD, author of Evaluation of the Association Between Gastric Acid Suppression and Risk of Intestinal Colonization With Multidrug-Resistant Microorganisms: A Systematic Review and Meta-analysis, and Todd Campbell Lee, MD MPH, author of Deprescribing Proton Pump Inhibitors: Overcoming Resistance

Interview with Sharon Saydah, PhD, MHS, author of Eye Care Among US Adults at High Risk for Vision Loss in the United States in 2002 and 2017

Aversion to debt products has contributed to renewed interest in the category

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Draft assessment confirms previous concerns about health effects of chlorinated solvent

Draft assessment confirms concerns about health effects of chlorinated solvent

US EPA finds unreasonable risks for 6 current uses, including chlor-alkali diaphragms

Inspector general finds agency hasn't reached out to those living near 9 chemical plants

Inspector general finds agency hasn't reached out to those living near 9 chemical plants

US EPA draft evaluation finds neurological effects associated with exposure to perchloroethylene

Long-lasting hair dyes are popular, and their safety has been well researched. But new epidemiology studies show their use correlates with increased risk of breast cancer

According to Dr K.J. Kiran, a top gastroenterologist, the lockdown is a dangerous environment for breeding habits that can lead to obesity

 Rating agency Moody’s said that the the negative outlook of India reflects increasing risks that economic growth will remain significantly lower than

Dhawan will assume charge from Saturday in place of Ashish Agarwal, the current chief risk officer, who will be transitioning to a new role in the bank