"Betty," the new series from "Skate Kitchen" and "The Wolfpack" director Crystal Moselle, premieres Friday on HBO.

In 'Upload,' a new Amazon comedy from 'The Office' and 'Parks and Recreation' whiz Greg Daniels, Robbie Amell stars as a man in a (digital) afterlife.

In HBO documentary "Natalie Wood: What Remains Behind," the star's daughter Natasha Gregson Wagner offers a personal counterpoint to true crime gossip.

SAMSUNG has refreshed its Galaxy Buds with a new Plus model offering something that Apple AirPods simply can't match. Here's our full Galaxy Buds+ review.

For a reasonable and fair review of our latest release, be sure to check out Jesse Smith’s review on Distro Watch here.

Ontario’s minister of long-term care has announced that the provincial government will conduct a review of the long-term care system once the COVID-19 pandemic settles.

Simon Pagenaud and Team Penske will be the featured honorees at Tuesday night's IndyCar Series awards ceremony at the Hilbert Circle Theatre (streamed on IndyCar.com beginning at 6:45 p.m.

He showed enough as a freshman to suggest IU has a bonafide Big Ten shooting guard in Armaan Franklin, waiting to be developed.

We are now quite familiar with customer-written hotel reviews; we also know about the trendy use of video reviews of hotels but what about reviews of flights?! Yesterday I stumbled upon an incredible amateur video that made it to the top #20 of the most watched video of Youtube. The statistics speak for themselves: Views: 76,062 Comments: 468 Favorited: [...]

Moving into the bigger leagues of fishing, where your hobbies are more professional and catching the biggest fish is key to improving your professional career. In such cases, you’re going to want to consider buying a product that really steps your game, without you having to worry about the price. A sport that necessarily was […]

The post Garmin echoMAP CHIRP 74Cv Review appeared first on Patriot Outdoor News.

A beachgoers favorite item must be the canopy tent. You can relax under it, watch the sea, and save yourself from the sun; all at the same time! Many of us even use these sheds in other places like parks, camps, mountains, and even backyards. When it comes to canopies, there’s actually no definite site. […]

The post CORE Instant Pop-Up Canopy Review appeared first on Patriot Outdoor News.

“Death Stranding” is one of the oddest, and one of the best, games of 2019.

The game ably emulates the manic tempo of being young, smart (and stupid) and having a wild night out.

The ways in which the game uses forced perspective and illusion to evoke the subconscious is thrilling.

Here’s how the NHL season is projected to end — with a look at some key stats that could make all the difference.

But they should make the playoffs!

Come aboard the Paul Gauguin cruise ship as I discuss the ship and the 7 things I think you need to know, and the 5 important watch-outs you need to consider before cruising on this luxury cruise ship. The Paul Gauguin cruises out of Tahiti on cruise vacations around the French Polynesia islands on cruising vacations from 7 to 14 nights. I show you the facilities on the ship.

Note: I travelled as a guest of Paul Gauguin before making this video. They had no input on the opinions or content of this video.

** Buy my Cruise T-shirts: http://bit.ly/TFTStore
** USA cruisers get great cruise deals CRUISEDIRECT.COM: http://bit.ly/TFTBookCruise
** UK Cruisers get great cruise deals with CRUISE.CO.UK: http://bit.ly/BookCruiseUK

Gary Bembridge's Tips For Travellers aims to help you make more of your precious travel time and money on land and when cruising the oceans or rivers of the world. To help you, in every video I draw on my first-hand tips and advice from travelling every month for over 20 years and 60+ cruises.

Follow Tips For Travellers on:
- Instagram: http://www.instagram.com/garybembridge
- Facebook: http://www.facebook.com/tipsfortravellers
- Twitter: http://www.twitter.com/garybembridge

Discover what it is like to fly Air Tahiti Nui Boeing Dreamliner in Poerava Business Class. I discuss and review the aircraft, layout, seats, food, drink, service and facilities on board. Find out of this airline and business class is a thumbs up or thumbs down from me.

Note: I received a discount off the full fare price of my Air Tahiti Business class flight from Paris to Papeete Tahiti. The airline had no input of the content or opinions expressed in my video.

** Subscribe to my channel: http://bit.ly/TFT_YouTube2
** Buy one of my unique Cruise T-shirts: http://bit.ly/TFTStore
** Get great cruise deals via CRUISEDIRECT.COM: http://bit.ly/TFTBookCruise

Gary Bembridge's Tips For Travellers aims to help you make more of your precious travel time and money on land and when cruising the oceans or rivers of the world. To help you, in every video I draw on my first-hand tips and advice from travelling every month for over 20 years and 60+ cruises.

Follow Tips For Travellers on:
- Instagram: http://www.instagram.com/garybembridge
- Facebook: http://www.facebook.com/tipsfortravellers
- Twitter: http://www.twitter.com/garybembridge

Discover the 7 essential things you need to know about Seabourn Cruises Entire cruise ship. Things you really need to know if you are interested in cruising on this luxury cruise ship. I tour all aspects of the ship and share my views on what os good and works less well. I explore many aspects of the ship including dining options, bars and lounges, fitness, entertainment, facilities and experience. Seabourn Cruises is one of the ultra-luxury cruise lines and Seabourn Encore was the first of a new class of ships for the cruise line. The sister ship is called Seabourn Ovation, and os basically the same ship.

Note: I travelled as a guest of the Seabourn Cruises before making this video. They had no input on the opinions or content of this video.

** Buy my Cruise T-shirts: http://bit.ly/TFTStore
** USA cruisers get great cruise deals CRUISEDIRECT.COM: http://bit.ly/TFTBookCruise
** UK Cruisers get great cruise deals with CRUISE.CO.UK: http://bit.ly/BookCruiseUK

Gary Bembridge's Tips For Travellers aims to help you make more of your precious travel time and money on land and when cruising the oceans or rivers of the world. To help you, in every video I draw on my first-hand tips and advice from travelling every month for over 20 years and 60+ cruises.

Follow Tips For Travellers on:
- Instagram: http://www.instagram.com/garybembridge
- Facebook: http://www.facebook.com/tipsfortravellers
- Twitter: http://www.twitter.com/garybembridge

#SeabournCruises #SeabournEncore #CruiseShipTour

Princess Cruises were the first cruise line to introduce the Ocean Medallion smart wearable device that is supposed to change the way you cruise. It helps you board the ship faster, find your way around the ship, order food and drink to wherever you are on the ship, gamble and play games , locate your friends and more. But how does it really work? What are the pros and cons? Find out my thoughts, take and review of the Princess Cruises Ocean Medallion.

TelcoTV released a preview of results from the annual Heavy Reading State of the Video Consumer Survey. Complete findings from the 2012 survey will be presented at the TelcoTV Conference and Expo taking place October 24 to 26, 2012 at the Las Vegas Hotel, Nevada. Aditya Kishore, Senior Analyst, Heavy Reading will present the findings during his keynote address on Wednesday, October 24, 2012.

Heavy Reading’s highly anticipated State of the Video Consumer Survey, now in its fifth year, is an annual report that reveals consumer opinions about video consumption across device platforms, provider perceptions and satisfaction levels with video services. In years past, it has proven to be a valuable planning tool for any organization serving the video distribution marketplace.

China says it supports a World Health Organisation-led review into the global response to the coronavirus outbreak, but only "after the pandemic is over".

This morning I took (early) delivery of Amazon’s new Kindle 3 – I opted for the WiFi only version – a device that claims 50% better contrast than any other e-reader, a 21% smaller body while keeping the same 6″ size reading area, and a 20% increase in the speed of page turns. These are, [...]

Announced back in July, Nokia’s new flagship N8 smartphone began shipping on the last day of September to those that had pre-ordered the device (it’s now available on most UK networks). As did the first review units sent out with almost military provision to chosen technology bloggers, this writer included. Having already declared “Nokia is [...]

On paper at least, Nokia’s E6 smartphone could have been designed just for me. It keeps most of the design cues and form-factor first seen on the E71 and its successor the E72 – easy one handed operation, great physical QWERTY keyboard, rock solid build (well, the E71 at least), superb call quality, free turn-by-turn [...]

I’m not entirely sure who the Samsung Galaxy Note is aimed at, but as somebody who gets to observe from the sidelines, this is one fun, functional and loveable device — although it comes at an out of contract price of around £450-500 upwards, give or take. The biggest talking point of the Galaxy Note is its [...]

velocityconf: New #velocityconf CA program preview is up: http://t.co/rKjf91RXdD @ariyahidayat on End-to-End JS Quality Analysis.

This past year, I predicted the fall of both Zuck and Trump, not to mention the triumph of cannabis and rationale markets. But in 2019, the sociopaths won – bigly. Damn, was I wrong. One year ago this week, I sat down to write my annual list of ten or so predictions for the coming … Continue reading "Predictions Review: Trump, Zuck Crush My Optimism In 2019"

Part of the They've got the look promo for the BBC UK Homepage

12 March 2015 , Volume 91, Number 2

Research Event

Event participants

Tim Jinks, Head of Drug-Resistant Infections Programme, Wellcome
Jim O’Neill, Chair, Review on Antimicrobial Resistance; Chair, Chatham House
Haileyesus Getahun, Director of Global Coordination and Partnership on Antimicrobial Resistance, World Health Organization 
Juan Lubroth, Chief Veterinary Officer, Food and Agriculture Organization (Videolink)
Jyoti Joshi, Head, South Asia, Center for Disease Dynamics, Economics & Policy
Estelle Mbadiwe, Coordinator-Nigeria, Global Antibiotic Resistance Partnership
Charles Clift, Senior Consulting Fellow, Chatham House; Report Author

8 January 2020 , Volume 96, Number 1

3 June 2013 , Volume 69, Number 3

Dark creations of European authors tell us much about our own world

3 June 2013 , Volume 69, Number 3

You’ve read Mankell and Larsson, but here are others to look out for:

This article is by L. James Rice.

Campfire Pro is a program that aims to be a comprehensive tool for worldbuilders, ranging from authors to game designers to TTRPG Gamemasters, which means it’s got many features to explore. With that in mind, it’s probably best to give a little overview of the product before delving into its details.

First off, between gaming, screenwriting, and writing in general, I’ve seen a lot of these sorts of programs over the years and been disappointed by them more often than not. Campfire’s user interface harkens back to many older programs, keeping things relatively simple, and if you’re looking flashy bells and whistles, they aren’t here. You can, however, beautify the background with a variety of themes as well as create your own. Where this program excels is in its most important aspect, functionality, while for me at least, the biggest downfall is a less than intuitive interface. This could just be my brain, results will vary, but don’t be surprised by a tiny learning curve and the occasional “good grief, did I really just do that?” This is more about little irritants than deal breakers, however, and a little tinkering tends to find answers.

Continue reading Review of Campfire Pro Writing Software at Mythic Scribes.

David A. Mitchell
Jun 1, 2006; 47:1118-1127
Thematic Reviews

Chi-Liang Eric Yen
Nov 1, 2008; 49:2283-2301
Thematic Reviews

Mohamad Navab
Jun 1, 2004; 45:993-1007
Thematic Reviews

WS Harris
Jun 1, 1989; 30:785-807
Reviews

John M. Dietschy
Aug 1, 2004; 45:1375-1397
Thematic Reviews

Weerapan Khovidhunkit
Jul 1, 2004; 45:1169-1196
Thematic Reviews

Dawn L. Brasaemle
Dec 1, 2007; 48:2547-2559
Thematic Reviews

JP Segrest
Feb 1, 1992; 33:141-166
Reviews

The study of protein subcellular distribution, their assembly into complexes and the set of proteins with which they interact with is essential to our understanding of fundamental biological processes. Complementary to traditional assays, proximity-dependent biotinylation (PDB) approaches coupled with mass spectrometry (such as BioID or APEX) have emerged as powerful techniques to study proximal protein interactions and the subcellular proteome in the context of living cells and organisms. Since their introduction in 2012, PDB approaches have been used in an increasing number of studies and the enzymes themselves have been subjected to intensive optimization. How these enzymes have been optimized and considerations for their use in proteomics experiments are important questions. Here, we review the structural diversity and mechanisms of the two main classes of PDB enzymes: the biotin protein ligases (BioID) and the peroxidases (APEX). We describe the engineering of these enzymes for PDB and review emerging applications, including the development of PDB for coincidence detection (split-PDB). Lastly, we briefly review enzyme selection and experimental design guidelines and reflect on the labeling chemistries and their implication for data interpretation.

Signaling networks process intra- and extracellular information to modulate the functions of a cell. Deregulation of signaling networks results in abnormal cellular physiological states and often drives diseases. Network responses to a stimulus or a drug treatment can be highly heterogeneous across cells in a tissue because of many sources of cellular genetic and non-genetic variance. Signaling network heterogeneity is the key to many biological processes, such as cell differentiation and drug resistance. Only recently, the emergence of multiplexed single-cell measurement technologies has made it possible to evaluate this heterogeneity. In this review, we categorize currently established single-cell signaling network profiling approaches by their methodology, coverage, and application, and we discuss the advantages and limitations of each type of technology. We also describe the available computational tools for network characterization using single-cell data and discuss potential confounding factors that need to be considered in single-cell signaling network analyses.

8 January 2020 , Volume 96, Number 1

• The Hobbit Review
• Christmas Movies
• What We Watched: Sunshine/Silver Lining's Playbook/The Grey/Argo

Research Event

Event participants

Tim Jinks, Head of Drug-Resistant Infections Programme, Wellcome
Jim O’Neill, Chair, Review on Antimicrobial Resistance; Chair, Chatham House
Haileyesus Getahun, Director of Global Coordination and Partnership on Antimicrobial Resistance, World Health Organization 
Juan Lubroth, Chief Veterinary Officer, Food and Agriculture Organization (Videolink)
Jyoti Joshi, Head, South Asia, Center for Disease Dynamics, Economics & Policy
Estelle Mbadiwe, Coordinator-Nigeria, Global Antibiotic Resistance Partnership
Charles Clift, Senior Consulting Fellow, Chatham House; Report Author

8 October 2019

A startling lack of progress on critical recommendations to tackle antimicrobial resistance is highlighted in this new global progress report, as well as opportunities for further action and key obstacles that need to be overcome.

Use the Download button to choose either the Research Paper, or the Background and Analysis Paper.