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Concentrations of Serum Vitamin D and the Metabolic Syndrome Among U.S. Adults

Earl S. Ford
May 1, 2005; 28:1228-1230
BR Metabolic Syndrome/Insulin Resistance Syndrome/Pre-Diabetes




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Coronary Heart Disease Incidence and Cardiovascular Mortality in Busselton with Reference to Glucose and Insulin Concentrations

T A Welborn
Mar 1, 1979; 2:154-160
Proceedings of the Kroc Foundation International Conference on Epidemiology of Diabetes and its Macrovascular Complications




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Table 1--Systeme International (SI) units for plasma, serum, or blood concentrations


Apr 1, 1994; 17:360-361
Syst[egrave]me International (SI) Units




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Table 1--Systeme International (SI) units for plasma, serum, or blood concentrations


Nov 1, 1995; 18:1524-1525
Syst[egrave]me International (SI) Units




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Effects of Coffee Consumption on Fasting Blood Glucose and Insulin Concentrations: Randomized controlled trials in healthy volunteers

Rob M. van Dam
Dec 1, 2004; 27:2990-2992
Brief Reports




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Table 1-Systeme International (SI) units for plasma, serum, or blood concentrations


Aug 1, 1995; 18:1223-1224
Syst[egrave]me International (SI) Units




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Central American Immigrants in the United States

While much attention has been paid to recent Central American arrivals at the U.S.-Mexico border, nearly half of the approximately 3.5 million Central Americans resident in the United States in 2017 arrived before 2000. About one-third are naturalized U.S. citizens, and they tend to participate in the labor force at a higher rate than foreign- and U.S.-born adults. Discover more about this population in this data-rich article.




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Inmigrantes centroamericanos en los Estados Unidos

Si bien se ha prestado mucha atención a los centroamericanos recién llegados a la frontera entre los Estados Unidos y México, casi la mitad de los aproximadamente 3.5 millones que vivían en los Estados Unidos en 2017 llegaron antes de 2000. Aproximadamente un tercio son ciudadanos estadounidenses y tienden a participar en la fuerza laboral con más frecuencia que otros extranjeros y estadounidenses. Descubra más en este artículo lleno de datos.




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Invertir en el Vecindario: Cambios en los Patrones de Migración Entre México y Estados Unidos y Oportunidades para una Cooperación Sostenible

Presentación del reporte que refleja el contenido de encuentros del grupo de estudio sobre la migración México-Estados Unidos convocado por El Colegio de México y el Migration Policy Institute (MPI).




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Promising Strategies for Reintegration of Migrants Returning to Mexico and Central America

This MPI webinar focuses on reception and reintegration services for returning migrants, along with the heightened pressure policymakers in Mexico and Central America are facing to design systems and programs that support both returnees and the communities in which they settle. Authors of a year-long study of reception and reintegration services in Mexico and the Northern Triangle discuss the findings of their fieldwork.




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Sustainable Reintegration: Strategies to Support Migrants Returning to Mexico and Central America

Reception and reintegration programs for deported and other returning migrants represent a long-term investment for migrant-origin and destination countries, holding the potential to reduce re-migration and permit communities of origin to benefit from the skills migrants learn abroad. This report offers recommendations to make reintegration programs more effective in Mexico and Central America.




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Dapagliflozin Versus Placebo on Left Ventricular Remodeling in Patients With Diabetes and Heart Failure: The REFORM Trial

OBJECTIVE

To determine the effects of dapagliflozin in patients with heart failure (HF) and type 2 diabetes mellitus (T2DM) on left ventricular (LV) remodeling using cardiac MRI.

RESEARCH DESIGN AND METHODS

We randomized 56 patients with T2DM and HF with LV systolic dysfunction to dapagliflozin 10 mg daily or placebo for 1 year, on top of usual therapy. The primary end point was difference in LV end-systolic volume (LVESV) using cardiac MRI. Key secondary end points included other measures of LV remodeling and clinical and biochemical parameters.

RESULTS

In our cohort, dapagliflozin had no effect on LVESV or any other parameter of LV remodeling. However, it reduced diastolic blood pressure and loop diuretic requirements while increasing hemoglobin, hematocrit, and ketone bodies. There was a trend toward lower weight.

CONCLUSIONS

We were unable to determine with certainty whether dapagliflozin in patients with T2DM and HF had any effect on LV remodeling. Whether the benefits of dapagliflozin in HF are due to remodeling or other mechanisms remains unknown.




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Metabolic Factors, Lifestyle Habits, and Possible Polyneuropathy in Early Type 2 Diabetes: A Nationwide Study of 5,249 Patients in the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Cohort

OBJECTIVE

To investigate the association of metabolic and lifestyle factors with possible diabetic polyneuropathy (DPN) and neuropathic pain in patients with early type 2 diabetes.

RESEARCH DESIGN AND METHODS

We thoroughly characterized 6,726 patients with recently diagnosed diabetes. After a median of 2.8 years, we sent a detailed questionnaire on neuropathy, including the Michigan Neuropathy Screening Instrument questionnaire (MNSIq), to identify possible DPN (score ≥4) and the Douleur Neuropathique en 4 Questions (DN4) questionnaire for possible associated neuropathic pain (MNSIq ≥4 + pain in both feet + DN4 score ≥3).

RESULTS

Among 5,249 patients with data on both DPN and pain, 17.9% (n = 938) had possible DPN, including 7.4% (n = 386) with possible neuropathic pain. In regression analyses, central obesity (waist circumference, waist-to-hip ratio, and waist-to-height ratio) was markedly associated with DPN. Other important metabolic factors associated with DPN included hypertriglyceridemia ≥1.7 mmol/L, adjusted prevalence ratio (aPR) 1.36 (95% CI 1.17; 1.59); decreased HDL cholesterol <1.0/1.2 mmol/L (male/female), aPR 1.35 (95% CI 1.12; 1.62); hs-CRP ≥3.0 mg/L, aPR 1.66 (95% CI 1.42; 1.94); C-peptide ≥1,550 pmol/L, aPR 1.72 (95% CI 1.43; 2.07); HbA1c ≥78 mmol/mol, aPR 1.42 (95% CI 1.06; 1.88); and antihypertensive drug use, aPR 1.34 (95% CI 1.16; 1.55). Smoking, aPR 1.50 (95% CI 1.24; 1.81), and lack of physical activity (0 vs. ≥3 days/week), aPR 1.61 (95% CI 1.39; 1.85), were also associated with DPN. Smoking, high alcohol intake, and failure to increase activity after diabetes diagnosis associated with neuropathic pain.

CONCLUSIONS

Possible DPN was associated with metabolic syndrome factors, insulin resistance, inflammation, and modifiable lifestyle habits in early type 2 diabetes.




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The Canadian Express Entry System for Selecting Economic Immigrants: Progress and Persistent Challenges

Since its launch in 2015, the Express Entry system has changed how economic immigration to Canada happens and how it fits into public and political debates. And while it has proven successful in cutting through application backlogs, some challenges remain. This report looks at how and why this points-based system was introduced, what its impact has been, and how it could be further finetuned.




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Invertir en el vecindario: Cambios en los patrones de migración entre México y Estados Unidos y oportunidades para una cooperación sostenible

La migración entre México y Estados Unidos ha cambiado dramáticamente en los últimos años, pero las políticas y la retórica política en ambos países no se han actualizado a este contexto a la misma velocidad. Este reporte explora esta nueva realidad migratoria y cómo los dos gobiernos podrían trabajar juntos para abordar los desafíos de políticas públicas que tienen en común.




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La Bienvenida Se Agota para Colombianos en Ecuador Mientras Venezolanos Se Hacen Más Visibles

Aunque colombianos encontraron un refugio cálido en Ecuador después de ser desplazados de su país por una guerra civil que duro décadas, la vida se ha vuelto más difícil para ellos en los últimos años, en parte como resultado del flujo de venezolanos que buscan seguridad. Este artículo se basa en encuestas de migrantes en Quito, comparando y contrastando las experiencias de colombianos y venezolanos, y evaluando sus percepciones de discriminación, victimización y esperanzas para el futuro.




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Restorative justice : an adjunct to the current punitive justice system / presented by Leigh Garrett, CEO OARS Community Transitions, including the Centre for Restorative Justice.




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Aligning to aliveness : a simple guide to heart-centred living / Robert Beno.




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Newstart allowance : is it time to raise it? / research undertaken by The South Australian Centre for Economic Studies, University of Adelaide ; funded by the Independent Research Fund.

This paper assesses whether the Newstart Allowance for unemployed people should be increased. It investigates the relationship of the Newstart Allowance to Average Weekly Earnings, the Federal Minimum Wage, and Australian poverty lines, and considers the typical the duration of unemployment and long term unemployment, duration of time on income support, overseas allowances, cost of living, and a comparison with policy makers' remuneration. It finds that the value of the allowance has eroded since it was first set and that unemployment for many is not a transitional situation, and concludes that an increase is warranted to bridge the gap to the poverty line.




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The Australian musical : from the beginning / Peter Pinne and Peter Wyllie Johnston ; foreword by John Kotzas, CEO Queensland Performing Arts Centre ; introduction by Mark Madama, Associate Professor of Musical Theatre, University of Michigan.

Lyricists -- Australia -- Biography.




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On the end of privacy : dissolving boundaries in a screen-centric world / Richard E. Miller.

Clementi, Tyler.




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Designing the John B Fairfax Learning Centre

The John B Fairfax Learning Centre is officially launched and we look forward to welcoming visitors to this fabulous new




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Des pressions centripetes (Epreuve de Gelle) etude de semeiologie auriculaire / par Le Docteur Georges Gelle.

Paris : Société d’éditions scientifiques, 1895.




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Deux ans entre senegal et niger / par Louis Lota.

Paris : Steinheil, 1887.




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Die functionen des centralnervensystems und ihre phylogenese / von J. Steiner.

Braunschweig : Druck und Verlag von Friedrich Vieweg und Sohn, 1898.




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Domestic sanitary drainage and plumbing : lectures on practical sanitation delivered to plumbers, engineers, and others in the Central Technical Institution, South Kensington, London ... / by William R. Maguire.

London : Kegan Paul, Trench, Trubner, 1890.




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Europa (right), grieving after her rape by Jupiter, is consoled by Venus and Cupid (centre); Jupiter disguised as a bull looks on from the left background. Engraving by T. Cook and R. Pollard, 1797, after B. West, 1772.

London (Braynes-Row, Spa-Fields) : Publish'd ... by R. Pollard printseller, Jany: 30th; 1797.




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On a computationally-scalable sparse formulation of the multidimensional and non-stationary maximum entropy principle. (arXiv:2005.03253v1 [stat.CO])

Data-driven modelling and computational predictions based on maximum entropy principle (MaxEnt-principle) aim at finding as-simple-as-possible - but not simpler then necessary - models that allow to avoid the data overfitting problem. We derive a multivariate non-parametric and non-stationary formulation of the MaxEnt-principle and show that its solution can be approximated through a numerical maximisation of the sparse constrained optimization problem with regularization. Application of the resulting algorithm to popular financial benchmarks reveals memoryless models allowing for simple and qualitative descriptions of the major stock market indexes data. We compare the obtained MaxEnt-models to the heteroschedastic models from the computational econometrics (GARCH, GARCH-GJR, MS-GARCH, GARCH-PML4) in terms of the model fit, complexity and prediction quality. We compare the resulting model log-likelihoods, the values of the Bayesian Information Criterion, posterior model probabilities, the quality of the data autocorrelation function fits as well as the Value-at-Risk prediction quality. We show that all of the considered seven major financial benchmark time series (DJI, SPX, FTSE, STOXX, SMI, HSI and N225) are better described by conditionally memoryless MaxEnt-models with nonstationary regime-switching than by the common econometric models with finite memory. This analysis also reveals a sparse network of statistically-significant temporal relations for the positive and negative latent variance changes among different markets. The code is provided for open access.




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Entries open for State Library’s $20,000 short film competition

Thursday 21 November 2019

The State Library of NSW is inviting entries for its short film prize Shortstacks, with a total of $20,000 on offer across two categories.




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Entries now open for the 2020 National Biography Award

Tuesday 10 December 2019

Entries are now open for the 2020 National Biography Award – Australia's richest prize for biography and memoir writing.




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Entries open for $40,000 award for female scriptwriters

Friday 6 March 2020
Nominations opened for the 2020 Mona Brand Award for Women Stage and Screen Writers.




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Add your entry to the great pandemic diary of 2020

Monday 4 May 2020
The State Library wants to capture the thoughts and feelings of the State via a new diary sharing platform launched TODAY.




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Concentration and consistency results for canonical and curved exponential-family models of random graphs

Michael Schweinberger, Jonathan Stewart.

Source: The Annals of Statistics, Volume 48, Number 1, 374--396.

Abstract:
Statistical inference for exponential-family models of random graphs with dependent edges is challenging. We stress the importance of additional structure and show that additional structure facilitates statistical inference. A simple example of a random graph with additional structure is a random graph with neighborhoods and local dependence within neighborhoods. We develop the first concentration and consistency results for maximum likelihood and $M$-estimators of a wide range of canonical and curved exponential-family models of random graphs with local dependence. All results are nonasymptotic and applicable to random graphs with finite populations of nodes, although asymptotic consistency results can be obtained as well. In addition, we show that additional structure can facilitate subgraph-to-graph estimation, and present concentration results for subgraph-to-graph estimators. As an application, we consider popular curved exponential-family models of random graphs, with local dependence induced by transitivity and parameter vectors whose dimensions depend on the number of nodes.




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A smeary central limit theorem for manifolds with application to high-dimensional spheres

Benjamin Eltzner, Stephan F. Huckemann.

Source: The Annals of Statistics, Volume 47, Number 6, 3360--3381.

Abstract:
The (CLT) central limit theorems for generalized Fréchet means (data descriptors assuming values in manifolds, such as intrinsic means, geodesics, etc.) on manifolds from the literature are only valid if a certain empirical process of Hessians of the Fréchet function converges suitably, as in the proof of the prototypical BP-CLT [ Ann. Statist. 33 (2005) 1225–1259]. This is not valid in many realistic scenarios and we provide for a new very general CLT. In particular, this includes scenarios where, in a suitable chart, the sample mean fluctuates asymptotically at a scale $n^{alpha }$ with exponents $alpha <1/2$ with a nonnormal distribution. As the BP-CLT yields only fluctuations that are, rescaled with $n^{1/2}$, asymptotically normal, just as the classical CLT for random vectors, these lower rates, somewhat loosely called smeariness, had to date been observed only on the circle. We make the concept of smeariness on manifolds precise, give an example for two-smeariness on spheres of arbitrary dimension, and show that smeariness, although “almost never” occurring, may have serious statistical implications on a continuum of sample scenarios nearby. In fact, this effect increases with dimension, striking in particular in high dimension low sample size scenarios.




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Concentration of the spectral norm of Erdős–Rényi random graphs

Gábor Lugosi, Shahar Mendelson, Nikita Zhivotovskiy.

Source: Bernoulli, Volume 26, Number 3, 2253--2274.

Abstract:
We present results on the concentration properties of the spectral norm $|A_{p}|$ of the adjacency matrix $A_{p}$ of an Erdős–Rényi random graph $G(n,p)$. First, we consider the Erdős–Rényi random graph process and prove that $|A_{p}|$ is uniformly concentrated over the range $pin[Clog n/n,1]$. The analysis is based on delocalization arguments, uniform laws of large numbers, together with the entropy method to prove concentration inequalities. As an application of our techniques, we prove sharp sub-Gaussian moment inequalities for $|A_{p}|$ for all $pin[clog^{3}n/n,1]$ that improve the general bounds of Alon, Krivelevich, and Vu ( Israel J. Math. 131 (2002) 259–267) and some of the more recent results of Erdős et al. ( Ann. Probab. 41 (2013) 2279–2375). Both results are consistent with the asymptotic result of Füredi and Komlós ( Combinatorica 1 (1981) 233–241) that holds for fixed $p$ as $n oinfty$.




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Around the entropic Talagrand inequality

Giovanni Conforti, Luigia Ripani.

Source: Bernoulli, Volume 26, Number 2, 1431--1452.

Abstract:
In this article, we study generalization of the classical Talagrand transport-entropy inequality in which the Wasserstein distance is replaced by the entropic transportation cost. This class of inequalities has been introduced in the recent work ( Probab. Theory Related Fields 174 (2019) 1–47), in connection with the study of Schrödinger bridges. We provide several equivalent characterizations in terms of reverse hypercontractivity for the heat semigroup, contractivity of the Hamilton–Jacobi–Bellman semigroup and dimension-free concentration of measure. Properties such as tensorization and relations to other functional inequalities are also investigated. In particular, we show that the inequalities studied in this article are implied by a Logarithmic Sobolev inequality and imply Talagrand inequality.




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Convergence and concentration of empirical measures under Wasserstein distance in unbounded functional spaces

Jing Lei.

Source: Bernoulli, Volume 26, Number 1, 767--798.

Abstract:
We provide upper bounds of the expected Wasserstein distance between a probability measure and its empirical version, generalizing recent results for finite dimensional Euclidean spaces and bounded functional spaces. Such a generalization can cover Euclidean spaces with large dimensionality, with the optimal dependence on the dimensionality. Our method also covers the important case of Gaussian processes in separable Hilbert spaces, with rate-optimal upper bounds for functional data distributions whose coordinates decay geometrically or polynomially. Moreover, our bounds of the expected value can be combined with mean-concentration results to yield improved exponential tail probability bounds for the Wasserstein error of empirical measures under Bernstein-type or log Sobolev-type conditions.




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Function-Specific Mixing Times and Concentration Away from Equilibrium

Maxim Rabinovich, Aaditya Ramdas, Michael I. Jordan, Martin J. Wainwright.

Source: Bayesian Analysis, Volume 15, Number 2, 505--532.

Abstract:
Slow mixing is the central hurdle is applications of Markov chains, especially those used for Monte Carlo approximations (MCMC). In the setting of Bayesian inference, it is often only of interest to estimate the stationary expectations of a small set of functions, and so the usual definition of mixing based on total variation convergence may be too conservative. Accordingly, we introduce function-specific analogs of mixing times and spectral gaps, and use them to prove Hoeffding-like function-specific concentration inequalities. These results show that it is possible for empirical expectations of functions to concentrate long before the underlying chain has mixed in the classical sense, and we show that the concentration rates we achieve are optimal up to constants. We use our techniques to derive confidence intervals that are sharper than those implied by both classical Markov-chain Hoeffding bounds and Berry-Esseen-corrected central limit theorem (CLT) bounds. For applications that require testing, rather than point estimation, we show similar improvements over recent sequential testing results for MCMC. We conclude by applying our framework to real-data examples of MCMC, providing evidence that our theory is both accurate and relevant to practice.




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Alleviating Spatial Confounding for Areal Data Problems by Displacing the Geographical Centroids

Marcos Oliveira Prates, Renato Martins Assunção, Erica Castilho Rodrigues.

Source: Bayesian Analysis, Volume 14, Number 2, 623--647.

Abstract:
Spatial confounding between the spatial random effects and fixed effects covariates has been recently discovered and showed that it may bring misleading interpretation to the model results. Techniques to alleviate this problem are based on decomposing the spatial random effect and fitting a restricted spatial regression. In this paper, we propose a different approach: a transformation of the geographic space to ensure that the unobserved spatial random effect added to the regression is orthogonal to the fixed effects covariates. Our approach, named SPOCK, has the additional benefit of providing a fast and simple computational method to estimate the parameters. Also, it does not constrain the distribution class assumed for the spatial error term. A simulation study and real data analyses are presented to better understand the advantages of the new method in comparison with the existing ones.




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Nurture versus Nature: Long-Term Impact of Forced Right-Handedness on Structure of Pericentral Cortex and Basal Ganglia

Stefan Klöppel
Mar 3, 2010; 30:3271-3275
BRIEF COMMUNICATION




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Nasal Respiration Entrains Human Limbic Oscillations and Modulates Cognitive Function

Christina Zelano
Dec 7, 2016; 36:12448-12467
Systems/Circuits




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Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain

Fiona Doetsch
Jul 1, 1997; 17:5046-5061
Articles




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Les banques centrales et la dette : des risques émergents pour l efficacité de la politique monétaire en Afrique

French translation of BIS Papers No 99 - Central banks and debt: emerging risks to the effectiveness of monetary policy in Africa?, October 2018.




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Monedas digitales emitidas por bancos centrales

Spanish version of executive summary of report on Central bank digital currencies published by the Committee on Payments and Market Infrastructures (CPMI) and the Markets Committee, March 2018.




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Las monedas digitales de bancos centrales podrían afectar a los pagos, la política monetaria y la estabilidad financiera

Spanish version of Press release about CPMI and the Markets Committee issuing a report on "Central bank digital currencies" (12 March 2018)




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Oportunidades y riesgos de la entrada de las big tech en el sector financiero

Spanish version of BIS Press Release - Big tech in finance: opportunities and risks, 23 June 2019




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2008-04-21: Cartoon Dispatches from Central Asia




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2008-05-15: Cartoon Dispatches from Central Asia




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Academy comments on government support for entrepreneurs




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National Engineering Policy Centre to provide advice to government on reaching net zero emissions