Conserving biodiverse habitats Contextual habitat intactness for biodiversity. Dark shades indicate high intactness, and colors indicate levels of human influence (Blue = wilderness, Green = low disturbance, Orange = modified, Pink = highly modified). Natural habitat loss contributes to biodiversity loss, and by some estimates nearly half a million species...

Premature infants have a higher incidence of indirect hyperbilirubinemia than term infants. Management of neonatal indirect hyperbilirubinemia in late preterm and term neonates has been well addressed by recognized, consensus-based guidelines. However, the extension of these guidelines to the preterm population has been an area of uncertainty because of limited evidence. This leads to variation in clinical practice and lack of recognition of the spectrum of bilirubin-induced neurologic dysfunction (BIND) in this population. Preterm infants are metabolically immature and at higher risk for BIND at lower bilirubin levels than their term counterparts. Early use of phototherapy to eliminate BIND and minimize the need for exchange transfusion is the goal of treatment in premature neonates. Although considered relatively safe, phototherapy does have side effects, and some NICUs tend to overuse phototherapy. In this review, we describe the epidemiology and pathophysiology of BIND in preterm neonates, and discuss our approach to standardized management of indirect hyperbilirubinemia in the vulnerable preterm population. The proposed treatment charts suggest early use of phototherapy in preterm neonates with the aim of reducing exposure to high irradiance levels, minimizing the need for exchange transfusions, and preventing BIND. The charts are pragmatic and have additional curves for stopping phototherapy and escalating its intensity. Having a standardized approach would support future research and quality improvement initiatives that examine dose and duration of phototherapy exposure with relation to outcomes.

Tobacco smoking is the primary risk factor for lung cancer, driven by the addictive nature of nicotine and the indisputable carcinogenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) as well as other compounds. The integration of lung cancer chemoprevention with smoking cessation is one potential approach to reduce this risk and mitigate lung cancer mortality. Experimental data from our group suggest that kava, commonly consumed in the South Pacific Islands as a beverage to promote relaxation, may reduce lung cancer risk by enhancing NNK detoxification and reducing NNK-derived DNA damage. Building upon these observations, we conducted a pilot clinical trial to evaluate the effects of a 7-day course of kava on NNK metabolism in active smokers. The primary objective was to compare urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL plus its glucuronides, major metabolites of NNK) before and after kava administration as an indicator of NNK detoxification. Secondary objectives included determining kava's safety, its effects on DNA damage, tobacco use, and cortisol (a biomarker of stress). Kava increased urinary excretion of total NNAL and reduced urinary 3-methyladenine in participants, suggestive of its ability to reduce the carcinogenicity of NNK. Kava also reduced urinary total nicotine equivalents, indicative of its potential to facilitate tobacco cessation. Plasma cortisol and urinary total cortisol equivalents were reduced upon kava use, which may contribute to reductions in tobacco use. These results demonstrate the potential of kava intake to reduce lung cancer risk among smokers.

Augmented, Virtual, and other mixed reality technologies are rapidly emerging and advancing, creating new and exciting opportunities for training and education. XR for Learning Weekly […]

The post XR for Learning Weekly – May 6, 2020 appeared first on e-Learning Feeds.

In light of the ongoing COVID-19 crisis, this week’s resources continue to have the dual focus of providing resources that can help us navigate this […]

The post David Kelly’s Curated L&D Content for the Week of 5/4/20 appeared first on e-Learning Feeds.

Augmented, Virtual, and other mixed reality technologies are rapidly emerging and advancing, creating new and exciting opportunities for training and education. XR for Learning Weekly […]

The post XR for Learning Weekly – April 29, 2020 appeared first on e-Learning Feeds.

In light of the ongoing COVID-19 crisis, this week’s resources continue to have the dual focus of providing resources that can help us navigate this […]

The post David Kelly’s Curated L&D Content for the Week of 4/27/20 appeared first on e-Learning Feeds.

Augmented, Virtual, and other mixed reality technologies are rapidly emerging and advancing, creating new and exciting opportunities for training and education. XR for Learning Weekly […]

The post XR for Learning Weekly – April 22, 2020 appeared first on e-Learning Feeds.

Paris Games Week 2020 organizer SELL announced it has cancelled this years event due to concerns over the ongoing coronavirus (COVID-19) pandemic. The event was set to run from October 23 to 27. 

Read the message from SELL below:

Dear players,

It is with great emotion that we have made the difficult decision to cancel Paris Games Week, initially scheduled from 23rd to 27th October and which would have marked our 10th anniversary.

The current context and the necessary anticipation of both the technical and logistical complexities of an event such as Paris Games Week have led us to cancel this edition.

This year should have been special, with a line-up full of new releases, and an anniversary edition which we were thrilled to celebrate with you.

We are going to work with all the industry players to enable us all to live our passion. We are already preparing next year’s edition and are looking forward to seeing you again.

Our Very Best Regards,

The Paris Games Week Team

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443416/paris-games-week-2020-cancelled-due-to-coronavirus-pandemic/

Season 5 of Respawn Entertainment’s hero-based battle royale kicks off next week and it looks like they’re doing more than just blowing up the map. This new Apex Legends trailer shows off what appears to be a horde mode PvE quest initiated by the newest Legend of the bunch: Loba. It looks like you’ll be […]

Get an all day breakfast on a pizza before you go on your killing spree. Only psychopaths will order this, is what I'm saying.

A South Dakota teenager has admitted to slaying a 16-year-old girl who “ran away” from home to live with him after they met on an online dating website, authorities said.

Michael Campbell, 17, pleaded guilty to first-degree manslaughter on Thursday for the death of Shayna Ritthaler, a 16-year-old from Moorcroft, Wyoming, who was reported missing from a local coffee shop on Oct. 3. Less than a week later, her body was found in the basement bedroom of Campbell’s home.

“We got into an argument and then I shot her,” Campbell said during a change-of-plea hearing on Thursday, before referring to the teenager as his girlfriend, according to the Associated Press. “I shot her in the head.”

Read more at The Daily Beast.

STATE pension age is continually being reviewed and altered by the government. The latest change occurred earlier this week.

Skybot F-850 will spend a week on the ISS charming astronauts with its sense of humor

Not every actor is Linney-caliber.

Anna Marie loses her mind as well as control of her mouth. Chris investigates the impacts of bringing Diet Coke into Mementos. Peter buys more games. Nathan finishes Final Fanatasy VIII just in time to start playing Final Fantasy VIII. And Kelley just tries to survive Bloodstained's framerate on the Switch.

Many countries are focusing coronavirus testing on people who have covid-19 symptoms. But regularly testing all essential workers would have more of an impact

ESPN+ subscribers can get a great deal on the Saturday PPV event.

The Simpsons officials have yet to respond to The Weeknd's public proposal.

The real house from ‘The Conjuring’ movie set to be...

The post The Real House From ‘The Conjuring’ To Be Live-Streamed For A Week appeared first on Man's World India.

A roundup of some of the most popular but completely untrue stories and visuals of the week. None of these are legit, even though they were shared widely on social media. The Associated Press checked them out. Here are the facts:

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CLAIM: Photo shows Joe Biden posing with former ...

Apple Inc said Friday it will reopen a handful of stores in four U.S. states starting next week, in the first resumption of physical retail operations since the iPhone maker shuttered all U.S. stores in mid-March.

The Men's Milan Fashion Week set for June will be postponed to mid-July and presented in purely digital format with photos and video to avoid the risk of coronavirus contagion, Italy's national fashion chamber said on Wednesday.

Paris will hold a men's fashion week in virtual format from July 9 to July 13 for the Men Spring/Summer collections 2021, organisers said on Wednesday.

Equity markets rallied on Friday, hitting weekly highs, and oil prices gained as more governments around the world began gradually reopening their economies and Sino-American trade tensions eased.

A week packed with U.S. economic data is likely to provide investors with more evidence of the extent to which the coronavirus pandemic has hit growth, sharpening the debate on whether a rebound in stocks has been justified amid an unprecedented slowdown.

Read our live coronavirus updates HERE Coronavirus: The symptoms

The PM was moved out of intensive care on Thursday evening

Temperatures in parts of Britain are likely to soar to 24C over the Easter Bank Holiday weekend, but the sunshine could be interrupted by some April showers.

Follow our live Covid-19 updates HERE Coronavirus: The symptoms

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Read our live coronavirus updates HERE Coronavirus: the symptoms

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Follow our live coronavirus updates HERE Coronavirus: the symptoms

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Britain is set to enjoy yet more sunshine as the mercury soars to highs of 23C in some areas later this week.

Coronavirus: the symptoms Follow our live updates here

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Hospital consultant and ward housekeeper are among latest NHS victims in London Follow our live coronavirus updates here Coronavirus: the symptoms

The winning Lotto numbers on Wednesday were 38, 57, 54, 43, 25, 37 and the bonus number was 17.

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Follow our live coronavirus updates HERE Coronavirus: the symptoms

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Coronavirus: The symptoms