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Defying all the impossibilities in politics, Revanth Reddy makes it as Telangana CM

Always willing to take the risk, he started his political career in the Legislature as an independent candidate in the Legislative Council




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Congress announces Revanth Reddy as CM of Telangana

The State party chief was named as Congress central leadership’s choice for the CLP chief on the basis of a report submitted by party observers; he will take oath as CM on December 7




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Delay in getting degree certificates leaves students of Lakshadweep worried




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Parliamentary Panel highlights significant delays in installation of telemetry systems in critical flood-prone areas

The Committee's report on the performance audit of schemes for flood control and forecasting underscores the need for urgent action to ensure timely and effective flood management




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Will be injustice to SC communities if internal reservation is delayed by Karnataka government: Basavaraj Bommai

Mr. Bommai was recently honoured by SC community leaders in Bengaluru for recommending internal reservation for SC communities back in 2023




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Tripura's connectivity project with Bangladesh may be delayed: Minister

Opening of Agartala-Akhaura rail link and Maitree bridge got further delayed due to the political turmoil and change in government in Bangladesh; this project was inaugurated by Prime Minister Narendra Modi and then Bangladesh PM Sheikh Hasina in 2023




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Harmeet clinches a double in Venezuela




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Saudi Arabia’s Army chief to visit Iran to bolster defence relations

Saudi Arabia’s top military official meets Iranian counterpart in Tehran for rare high-level talks, focusing on defence diplomacy and cooperation




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Trump picks Kristi Noem for Homeland Security Secretary: report

Noem faced widespread backlash in April when she wrote in a memoir that she shot to death an "untrainable" dog that she "hated" on her family farm




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Argument over ‘extramarital’ relationship leads to death of three men in family in Kakinada

The police registered a case and the investigation is on




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Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of L-lactate

Anal. Methods, 2024, 16,2077-2084
DOI: 10.1039/D4AY00041B, Paper
Wenjuan Wang, Danrong Chen, Yujiao Cai, Zijing Liu, Hongfen Yang, Hongbin Xie, Jinquan Liu, Shengyuan Yang
Here, we show a paper-based POCT sensor based on lactate dehydrogenase-mediated alginate gelation combined with visual distance reading and smartphone-assisted colorimetric dual-signal analysis to determine the concentration of L-lactate in yogurt samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




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​Delay and bail: On former Tamil Nadu Minister V. Senthilbalaji’s case

Senthilbalaji’s release on bail was overdue, but he should not be made a Minister




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Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer

RSC Med. Chem., 2024, 15,3433-3443
DOI: 10.1039/D4MD00468J, Research Article
Meijuan Liu, Na Li, Zhaoxue Wang, Shuo Wang, Shaoda Ren, Xiaojing Li
A synthetic celastrol derivative (Cel-N) attenuates cancer cell stemness, inhibits the STAT3 pathway, and exerts anti-ovarian cancer effects in cell and mouse models.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists

RSC Med. Chem., 2024, 15,3616-3624
DOI: 10.1039/D4MD00306C, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. Sheldrake
Cyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design, synthesis, and structure–activity relationship studies of 6H-benzo[b]indeno[1,2-d]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00537F, Research Article
Open Access
Abdelfattah Faouzi, Alexandre Arnaud, François Hallé, Jean Roussel, Mandy Aymard, Vincent Denavit, Cong Viet Do, Angélique Mularoni, Mohamed Salah, Ahmed ElHady, Thanh-Nhat Pham, Alexandre Bancet, Marc Le Borgne, Raphaël Terreux, Roland Barret, Matthias Engel, Thierry Lomberget
A series of sulfur-containing tetracycles was designed and evaluated for their ability to inhibit protein kinase DYRK1A, a target known to have several potential therapeutic applications including cancers, Down syndrome or Alzheimer's disease.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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3-Thio-3,4,5-Trisubstituted-1,2,4-Triazoles: High Affinity Somatostatin Receptor-4 Agonist Synthesis and Structure-Activity Relationships

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00597J, Research Article
Albert Michael Crider, Audrey Hospital, Karin Sandoval, William Neumann, Stephen Kukielski, Lejla Garic, Kristen Ingold, Matthew Dunahoo, Khush Srabony, Rafael Frare, Olivia Slater, Nathan Peel, Maria Kontoyianni, Ken Witt
Somatostatin receptor-4 (SST4) is a therapeutic target for several conditions, including Alzheimer’s disease, seizures, neuropsychiatric disorders, and pain. Our previous work on 1,2,4-triazole derivatives led to enhanced SST4 binding affinity,...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Tiruchi Corporation office expansion plan witnesses more delay




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Association holds protest against delay in Anna University’s staff absorption, promotions




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DGCA approves Drone Academy at Telangana Agri University

It offers six-week training to ryots, agri-graduates, rural youth in drone piloting




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A natural farm from wasteland at Andhra University in Visakhapatnam

The Andhra University Avani Organics Gardening Hub in Visakhapatnam has grown into a thriving natural farm and is building a community of urban dwellers that is transforming a wasteland into a patch of green




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UAS Dharwad to host Krishi Mela from September 21

UAS Vice-Chancellor P. L. Patil said that the main objective of this year’s Krishi Mela is to provide information on various aspects of climate change to farmers




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Delay in handover of units from Goa to Daman leaves investors in limbo




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Delay over handover of industrial estate from Goa to Daman and Diu leaves investors




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Polls to rural local bodies, due late December, may be delayed

This is because the process of re-organisation of local bodies in general and village panchayats in particular is not yet complete. An official, who handled the previous round of local bodies’ polls, says this may take three to four months




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Stress amplification and relaxation imaging around cracks in nanocomposite gels using ultrasound elastography

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00909F, Paper
H. Le Blay, T. Deffieux, L. Laiarinandrasana, M. Tanter, A. Marcellan
Stress visualization around cracks in NC gels was performed using ultrasonic elastography. Temporal and spatial mapping are performed non-invasively. Over time, the stress gradient is erased by large-scale reorganization of the polymer network.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Telephone cord blister formation in solvent swollen elastomer films

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM01035C, Paper
Open Access
James S. Sharp, Nathaniel M. Roberts, Sam Walker
Telephone cord blister formation is studied in PDMS films swollen in four different solvents. Buckling and fracture mechanics theories are developed to interpret blister morphology and growth rates. A simple surface patterning method is introduced.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Modeling nematic phase main-chain liquid crystal elastomer synthesis, mechanics, and thermal actuation via coarse-grained molecular dynamics

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00528G, Paper
Nicolas Herard, Raja Annapooranan, Todd Henry, Martin Kroger, Shengqiang Cai, Nicholas Boechler, Yelena Sliozberg
This paper presents a coarse-grained molecular dynamics simulation study of the synthesis, mechanics, and thermal actuation of nematic phase main-chain liquid crystal elastomers (LCEs), a type of soft, temperature-responsive, polymeric...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Dynamical crossovers and correlations in a harmonic chain of active particles

Soft Matter, 2024, 20,8638-8653
DOI: 10.1039/D4SM00350K, Paper
Subhajit Paul, Abhishek Dhar, Debasish Chaudhuri
We explore the dynamics of a tracer in a harmonic chain of active particles, investigating the influence of interactions. Depending upon the time-scales governed by the interaction and the persistence of activity, we explore crossovers between different scaling behaviors of its dynamics.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Enhanced chemotaxis efficiency of Escherichia coli in viscoelastic solutions

Soft Matter, 2024, 20,8675-8683
DOI: 10.1039/D4SM01094A, Paper
Shaoying Zhu, Rui He, Caijuan Yue, Rongjing Zhang, Junhua Yuan
E. coli shows enhanced chemotaxis in viscoelastic media, with faster migration and higher accumulation in attractant-rich areas compared to Newtonian conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Interfacial viscoelasticity in oscillating drops of cyclodextrin-surfactant aqueous solution: experiments and theory

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM01007H, Paper
José Roberto Romero-Arias, Alberto S. Luviano, Miguel Costas, Aurora Hernandez-Machado, Rafael A Barrio
We present experiments involving oscillating droplets in aqueous cyclodextrin-surfactant solutions. In these experiments, α-cyclodextrin (αCD) and anionic surfactants exhibit remarkable viscoelasticity at the liquid/air interface, with dilatational modulus varying across...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A dynamical system approach to relaxation in glass-forming liquids

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00976B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jack F. Douglas, Qi-Lu Yuan, Jiarui Zhang, Hao Zhang, Wen-Sheng Xu
We adapt a dynamical system approach to the practical matter of estimating relaxation times in both cooled liquids and crystals at elevated temperatures, which we identify as weakly non-integrable dynamical systems.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A long-distance relationship

S. Balaji, who has run thousands of kilometres, talks about what it takes to be a marathon runner




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Reflections on Practice : Relationship Building / directed by: Nettie Wild ; production agencies: National Film Board of Canada (Montreal), British Columbia Centre for Disease Control. Street Nurse Program (Vancouver)

Montreal : National Film Board of Canada, 2019




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Revanth Reddy’s lost opportunity in Telangana

Telangana does not need yet another committee to study SC sub-categorisation




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Maharashtra elections 2024: Six in 10 Maharashtrians relate more to the national identity than the regional

Two in 10 believe that they are Maharashtrian first, Indian later. A little over one-sixth of the respondents favoured both identities equally.




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Patrons rue regular delays in operation of Mumbai CSMT-Mangaluru Junction Superfast Express

Konkan Railway Corporation Ltd. says it was undertaking careful scheduling, including revision in timetable, to ensure punctuality in operations




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Don’t delay loan sanction and disbursal to central schemes beneficiaries, Srinivas Poojary tells banks




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Bring next sahitya sammelana to Dakshina Kannada, MLC tells parishat office-bearers




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Third Vishwa Havyaka Sammelana in Bengaluru for three days from December 27




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Air India flight from Mangaluru to Mumbai departs after over-three-hour delay

An Air India official attributed the delay to ‘technical issues’




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'Olla' review: Revelatory and enigmatic

Helmed by a striking protagonist, Ariane Labed's directorial debut short is a visually-poised study of a skewed relationship




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Brigade to develop ₹600 crore residential complex in Velachery, Chennai

The development will be situated at the former Raptakos, Brett & Company Limited facility, which has been inactive for years. 




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Lepakshi crafts mela gets under way

The exhibition was launched by Revenue Divisional Officer S. Venkata Rao and can be called as the perfect place to shop for college-going girls.




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Craft mela by Rakalai Handicrafts




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Towards the total synthesis of mandelalide B: construction of the tetrahydrofuran/α-hydroxyl lactone fragment

Org. Chem. Front., 2024, 11,6353-6357
DOI: 10.1039/D4QO01433B, Research Article
Jia-Lei Yan, Jie Yu, Yingying Cheng, Mingze Yang, Zhengshuang Xu, Tao Ye
A stereocontrolled synthesis of the tetrahydrofuran/α-hydroxy lactone fragment of mandelalide B has been accomplished. The synthesis features a Horner-Wadsworth-Emmons fragment assembly strategy and a highly stereospecific iodine-induced cyclization.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Probing Intersystem Crossing in Multi-brominated Eumelanin through Transient Absorption and Surface Hopping Dynamics

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO01832J, Research Article
Open Access
Kavya Vinod, Lukhmanul Hakeem K., Diana Thomas, Pallavi Panthakkal Das, Mahesh Hariharan
Achieving intersystem crossing (ISC) through structural tuning in biological systems is an evolving area for therapeutic and materials research. Eumelanin, a natural pigment, offers huge potential for bio-inspired material design,...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Telangana Cyber Security Bureau conducts digital awareness campaign for senior citizens




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Telangana CID arrests two involved in pan-India job fraud racket




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Telangana pharmaceutical industries logged 97 major fire accidents in past decade: Fire Services Director-General Y. Nagi Reddy

The new government would like to decentralise and set up pharma villages, in 10 clusters, Special Chief Secretary Jayesh Ranjan said




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HYDRAA created fear among encroachers and big builders and not common people: Telangana CM