In an engine having a plurality of cylinders in which a plurality of fuel injection valves are provided respectively, fuel is injected at a predetermined injection ratio, and an abnormality of air-fuel ratio variation is detected. If a fuel injection amount of at least one of the plurality of the fuel injection valves is smaller than a predetermined reference value, the fuel injection amount is increased so as to become equal to or larger than the reference value.

A measurement gauge, comprising a pair of jaws biased in a closed position; a normalizing member surrounding one of the jaws when the pair of jaws is closed, the normalizing member biased in an extended position; a handle coupled to the pair of jaws and normalizing member such that movement from an extended handle position to an retracted handle position opens the pair of jaws and moves the normalizing member to an retracted position.

An abnormality detecting apparatus (10) for a rotating machine includes: a calculating part (15) which calculates a phase difference between signals respectively output from two sensors of one or more sets, the one or more sets being predetermined combinations of two sensors among the plurality of sensors, the plurality of sensors each of which detects an elastic wave generating in the rotating machine (1) having a rotor during rotation of the rotor, the sensors being arranged at predetermined different locations of the rotating machine (1); a storing part (16) which stores in advance information concerning a relationship between a phase difference and a contact position when a contact occurs during the rotation of the rotor, regarding the one or more sets; and a specifying part (17) which specifies a contact position by using a phase difference calculated by the calculating part (15) and the information stored in the storing part (16).

The diagnosis of male infertility is based predominantly on the results of standard semen analysis for concentration, total motility, progressive motility, volume, pH, viscosity and/or morphology. When sperm enter the female reproductive tract, they must undergo a series of physiological changes, known as capacitation, in order to fertilize an egg. This process involves plasma membrane changes that occur in response to stimuli within the female tract. These changes include removal of sterols and redistribution of the ganglioside GM1. Semen analysis identifies only half the cases of male infertility due to standard semen analysis providing little information on sperm functional competence. Previous data demonstrated that localization of the ganglioside, GM1, identifies sub-populations of sperm capable of undergoing the functional maturation process known as capacitation and tracks strongly with fertility.

This episode, we have a wide-ranging convo with Gene “No Malice” Thornton of Clipse. No Malice (formerly just Malice, before a religious epiphany several years back) and his brother Terrance, a.k.a. Pusha T, form one of rap’s greatest duos. Their smart, vicious raps — often about their real-life experiences dealing cocaine — first brought them to prominence with the massive hit “Grindin’” back in 2002. The group quickly became a critical and commercial favorite, thanks to the brothers’ rhymes and some production help from The Neptunes.

But after some label issues and legal problems, Clipse went on hiatus. No Malice released his solo debut and a memoir, while his brother joined forces with Kanye West. We talk to No Malice about God, going solo, the past (and future) of Clipse, which lyric he regrets most, and more.

See http://theciphershow.com/episode/78/ for full show notes and comments.

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One reader reports success with molasses for normalizing bowel movements.

As zoos are closed to visitors due to coronavirus, zookeepers trying to exercise animals by talking them for walks around the zoo.

David Kelly from the Maayu Mali Residential Rehabilitation Centre in Moree

A national fertility business attached to clinics in six Australian states and territories says its email system has been subjected to a "malicious cyber attack", with patients reporting receiving bogus messages that appear to be from the company.

A report by Human Rights Watch says new regulations to tighten the use of chemical restraints on dementia patients has actually normalised the treatment to the detriment of patients.

For the first time two overall winners have won the prestigious David Malin Awards which honours the best in Australian astrophotography.

(United States Ninth Circuit) - Revived a textile company's copyright infringement claims accusing certain competitors of illegally copying its floral lace designs. Reversed dismissals.

(United States Ninth Circuit) - Revived a textile company's copyright infringement claims accusing certain competitors of illegally copying its floral lace designs. Reversed dismissals.

Actress and left-wing activist Alyssa Milano has promoted a deceptively edited video about Vice President Mike Pence that was created by late-night talk show host Jimmy Kimmel -- even though the video has been debunked and Kimmel has publicly apologized for it.

The documentary hits Netflix tomorrow.

Get the tissues ready.

The documentary hits Netflix tomorrow.

The First Daughters are giving us all the feels.

Zero-click remote-code exec hole found by Googler, updates emitted

Samsung has patched a serious security hole in its smartphones that can be exploited by maliciously crafted text messages to hijack devices.…

Familial dysautonomia (FD) is the most prevalent form of hereditary sensory and autonomic neuropathy (HSAN). In FD, a germline mutation in the Elp1 gene leads to Elp1 protein decrease that causes sympathetic neuron death and sympathetic nervous system dysfunction (dysautonomia). Elp1 is best known as a scaffolding protein within the nuclear hetero-hexameric transcriptional Elongator protein complex, but how it functions in sympathetic neuron survival is very poorly understood. Here, we identified a cytoplasmic function for Elp1 in sympathetic neurons that was essential for retrograde nerve growth factor (NGF) signaling and neuron target tissue innervation and survival. Elp1 was found to bind to internalized TrkA receptors in an NGF-dependent manner, where it was essential for maintaining TrkA receptor phosphorylation (activation) by regulating PTPN6 (Shp1) phosphatase activity within the signaling complex. In the absence of Elp1, Shp1 was hyperactivated, leading to premature TrkA receptor dephosphorylation, which resulted in retrograde signaling failure and neuron death. Inhibiting Shp1 phosphatase activity in the absence of Elp1 rescued NGF-dependent retrograde signaling, and in an animal model of FD it rescued abnormal sympathetic target tissue innervation. These results suggest that regulation of retrograde NGF signaling in sympathetic neurons by Elp1 may explain sympathetic neuron loss and physiologic dysautonomia in patients with FD.

Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there is no consensus on the implications of PAE on metabolic disease risk in adults. Here, we describe a cohort of adults with FASDs that had an increased incidence of metabolic abnormalities, including type 2 diabetes, low HDL, high triglycerides, and female-specific overweight and obesity. Using a zebrafish model for PAE, we performed population studies to elucidate the metabolic disease seen in the clinical cohort. Embryonic alcohol exposure (EAE) in male zebrafish increased the propensity for diet-induced obesity and fasting hyperglycemia in adulthood. We identified several consequences of EAE that may contribute to these phenotypes, including a reduction in adult locomotor activity, alterations in visceral adipose tissue and hepatic development, and persistent diet-responsive transcriptional changes. Taken together, our findings define metabolic vulnerabilities due to EAE and provide evidence that behavioral changes and primary organ dysfunction contribute to resultant metabolic abnormalities.

Advancements in assistive image analytics and deep learning technology could in the future help doctors in the fight against preventable blindness.

The growls from the caged hyena reverberate through the room as Mohamed Sheikh Yakub slumps silently in a chair nearby, hoping the animal will frighten away the evil spirits he says have troubled him since his divorce.

As Thailand's capital cautiously reopens many restaurants shuttered over coronavirus fears, the feline "employees" of the Caturday Cafe are back at work.

Cybersecurity researchers from ESET on Thursday said they took down a portion of a malware botnet comprising at least 35,000 compromised Windows systems that attackers were secretly using to mine Monero cryptocurrency. The botnet, named "VictoryGate," has been active since May 2019, with infections mainly reported in Latin America, particularly Peru accounting for 90% of the compromised

Twelve weeks after the outbreak of the coronavirus epidemic in China, leaders in Beijing are gradually reopening the country. But how can they be sure their decision won't backfire?

Malik Thomas of La Verne Damien committed to USC on Friday as the Trojans' 2021 class landed another highly rated shooting guard within the same week.

A new outfitter brings all-inclusive camping to the 67-mile Backbone Trail.

Malibu has long been associated with cars full of beachgoers and staggering cliffside mansions — but there's much more to these "21 miles of scenic beauty."

A Malibu beach house designed by noted moderist architect Jerrold Lomax gets a makeover from Lomax's onetime protégé Zoltan E. Pali.

The schools are closing Friday and Monday for deep cleaning and staff meetings after "a community member with children in our schools" was exposed to the virus, the district said.

"Hair Love" filmmakers Matthew A. Cherry and Karen Rupert Toliver discuss their animated short, which is nominated for a 2020 Oscar.

Malibu's offbeat pyramid house has sold to a former Warner Bros. executive for $2.02 million.

The oceanfront home of billionaire philanthropist Eli Broad is for sale in Malibu at $75 million.

The site of French singer-composer Sébastien Izambard's Malibu home, which was destroyed in the 2018 Woolsey fire, is for sale at $4.5 million.

Neptune's Net, the most-beloved hangout in Malibu, is a roadhouse that is equal parts good grub and floor show. Neptune's Net tastes like that wave that just broke your board.

Gigi Hadid officially confirms to Jimmy Fallon she and Zayn Malik are expecting a baby.

After his name popped up in trade rumors the Colts spent a third-round pick on a safety. Are the Colts preparing for a future without Malik Hooker?

Safety Malik Hooker now only under contract with the Colts through 2020 season

Heavy rains across the region have also destroyed homes, crops and some infrastructure.

A chronology of key events

A chronology of key events

An overview of Somaliland, including key facts, political leaders and notes on the media

Key facts, figures and dates

Key facts, figures and dates

If you’re not put off by its low-key, text-centered nature you're likely to fall for this thoughtful, serene game.

Former defence minister says cargo plane shot down as it tried to land in the southern town of Bardale.