Canada’s provinces and territories began postponing elective medical and surgical procedures days after COVID-19 was declared a pandemic. Patients fearful for their health say advocating for care may make a difference.

Feral pigs capable of leaving behind industrial-looking trails of destruction are posing a threat to one of the world's most significant archaeological sites.

The mother of Perth girl Denishar Woods, left with severe brain damage after a severe electric shock, has been waiting for a report into the accident, but it fails to establish who is to blame.

At least 11 homes had already been destroyed at Binna Burra.

Flames fanned by strong winds caused extensive damage to the resort site, destroying the heritage-listed wooden lodge building that had stood since the 1930s.

MORNING BRIEFING: The Rural Fire Service says it will begin assessing the full extent of the bushfire damage in northern New South Wales today, and a man is charged after a robbery in 2003.

Israel Folau claims he could have one day skippered a "trophy-winning Wallabies team", as he seeks $14 million in damages following his Rugby Australia sacking.

Catherine Hamlin was born in Sydney. She worked in Ethiopia pioneering medical treatment for young women damaged by unsuccessful childbirth. In 2000, Pauline Newman visited Catherine Hamlin and her famous hospital in Addis Ababa. Catherine Hamlin died in March 2020 at the age of 93. By way of tribute today we revisit Pauline’s program from nearly 20 years ago.

A boy who stole from a pizza delivery driver and caused $6,000 damage to a vehicle at a construction site was being given cannabis by his family at the time, a court has heard.

Canberra Grammar students discover the unexpected benefits of rebuilding damaged classrooms in Nepal, as they form special bonds with school hosts in the heart of the Himalayas.

Riverland growers assess the damage to crops after a sudden hailstorm cut through the region late last night, wiping out crops in minutes.

Internet search giant Google is ordered to pay $40,000 in damages to Melbourne lawyer George Defteros after a Supreme Court of Victoria ruling found the internet giant was a publisher, and had defamed the man.

After undergoing a multi-million dollar development, the Port Pirie smelter is once again not producing anything.

A trampoline lands on the roof of a Hobart home, piercing a bedroom ceiling, as strong winds of up to 155 kilometres per hour wreak havoc in southern Tasmania overnight.

The redevelopment of the Royal Hobart Hospital continues to be beset with problems, the latest involving $1 million in construction damage.

Bioscientists are developing 3D printed artificial tissues that may help heal bone and cartilage typically damaged in sports-related injuries.

Concerns are raised about Charles Sturt University's spending priorities and credibility after a number of conditions were attached to the facility's registration.

Authorities were warned that a teenage boy with severe cognitive impairments was deteriorating in Darwin's Don Dale youth detention centre and needed help, before he joined in on a riot for which he may now go to adult jail.

Wielding an oversized wooden spoon, this popular Darwin laksa restaurateur, prepared for battle over a median strip, has taken to social media with a comical protest video.

When director Justin Pemberton began screening his new documentary at film festivals in 2019, the movie’s warnings of another financial meltdown seemed like a far-off problem. But then the coronavirus pandemic sent the global economy into a tailspin.

The Canadian Pharmacy Spammers are at it again, or should we say still at it again.

After Hurricane Dorian savaged the northern islands of the Bahamas, damaged properties loom as a target for real estate speculators.

Some patients who have recovered from coronavirus infection are suffering lasting damage, including liver damage, heart damage and blood clotting problems.

THE CORONAVIRUS lockdown is now causing serious damage to the UK's economy, Tory MP Steve Baker has warned - stressing he was now "gravely concerned" at the situation

DONALD Trump's bid to win a second term in the White House could be damaged by coronavirus because he can no longer hold the rallies that swept him to power.

Indianapolis' nonprofit arts sector supports about 30,000 jobs. The closures forced by coronavirus are causing damage to theaters, artists and more.

Indianapolis Contemporary is closing permanently, almost a year after changing its name and a few months after hiring a new executive director.

The fire broke out on the roof of the 800 Cap Apartments, 800 N. Capitol Ave., at about 1:30 a.m. Tuesday, IFD Battalion Chief Rita Reith said.

Thousands remain without power after severe storms moved through Hamilton County. Westfield reported several transmission poles were down in the area.

A family of four was able to safely get out of their house after a fire caused $200,000 of damage.

Two new books critical of the president -- one from the left, one from the right -- imagine a path beyond our current divisions.

The following article, BREAKING: Sen Marsha Blackburn Introduces Stop COVID Act…Allowing US Citizens To Sue Communist China For Damage They’ve Inflicted On Our Nation, was first published on 100PercentFedUp.com.

Yesterday, Senator Marsha Blackburn (R-TN), along with Senator Martha McSally (R-AZ) introduced the Stop COVID Act, giving Americans the ability to sue Communist China for the damage they’ve inflicted on our nation. Senator Blackburn appeared on Fox News with host Judge Jeanine where she explained the act to Jeanine Pirro. Blackburn told the Fox News […]

Continue reading: BREAKING: Sen Marsha Blackburn Introduces Stop COVID Act…Allowing US Citizens To Sue Communist China For Damage They’ve Inflicted On Our Nation ...

Incorporation of ribonucleotides into DNA can severely diminish genome integrity. However, how ribonucleotides instigate DNA damage is poorly understood. In DNA, they can promote replication stress and genomic instability and have been implicated in several diseases. We report here the impact of the ribonucleotide rATP and of its naturally occurring damaged analog 1,N6-ethenoadenosine (1,N6-ϵrA) on translesion synthesis (TLS), mediated by human DNA polymerase η (hpol η), and on RNase H2–mediated incision. Mass spectral analysis revealed that 1,N6-ϵrA in DNA generates extensive frameshifts during TLS, which can lead to genomic instability. Moreover, steady-state kinetic analysis of the TLS process indicated that deoxypurines (i.e. dATP and dGTP) are inserted predominantly opposite 1,N6-ϵrA. We also show that hpol η acts as a reverse transcriptase in the presence of damaged ribonucleotide 1,N6-ϵrA but has poor RNA primer extension activities. Steady-state kinetic analysis of reverse transcription and RNA primer extension showed that hpol η favors the addition of dATP and dGTP opposite 1,N6-ϵrA. We also found that RNase H2 recognizes 1,N6-ϵrA but has limited incision activity across from this lesion, which can lead to the persistence of this detrimental DNA adduct. We conclude that the damaged and unrepaired ribonucleotide 1,N6-ϵrA in DNA exhibits mutagenic potential and can also alter the reading frame in an mRNA transcript because 1,N6-ϵrA is incompletely incised by RNase H2.