z Chatham House Prize 2018: The Committee to Protect Journalists By feedproxy.google.com Published On :: Wed, 28 Nov 2018 00:00:00 +0000 Full Article
z Undercurrents: Episode 24 - Christmas Quiz By feedproxy.google.com Published On :: Thu, 20 Dec 2018 00:00:00 +0000 Full Article
z Radical Change? New Political Paradigms in Brazil and Mexico By feedproxy.google.com Published On :: Tue, 12 Feb 2019 00:00:00 +0000 Full Article
z The Militarization of the Black Sea After the Annexation of Crimea By feedproxy.google.com Published On :: Wed, 13 Mar 2019 00:00:00 +0000 Full Article
z Citizenship and Discontent in the Middle East By feedproxy.google.com Published On :: Wed, 15 May 2019 00:00:00 +0100 Full Article
z Undercurrents: Episode 33 - Chinese Millennials, and Attacks on Infrastructure in Gaza By feedproxy.google.com Published On :: Thu, 16 May 2019 00:00:00 +0100 Full Article
z Zimbabwe’s International Engagement By feedproxy.google.com Published On :: Fri, 12 Jul 2019 00:00:00 +0100 Full Article
z Undercurrents: Summer Special - Andrés Rozental on Mexican Politics By feedproxy.google.com Published On :: Thu, 01 Aug 2019 00:00:00 +0100 Full Article
z Kazakhstan: Tested by Transition By feedproxy.google.com Published On :: Thu, 28 Nov 2019 00:00:00 +0000 Full Article
z Undercurrents: Episode 41 - Personalized Political Advertising, and Climate Justice in Chile By feedproxy.google.com Published On :: Fri, 29 Nov 2019 00:00:00 +0000 Full Article
z Angola's Business Promise: Evaluating the Progress of Privatization and Other Economic Reforms By feedproxy.google.com Published On :: Tue, 21 Jan 2020 00:00:00 +0000 Full Article
z Undercurrents: Episode 45 - Politics in Kazakhstan, and Youth Engagement in Politics By feedproxy.google.com Published On :: Mon, 10 Feb 2020 00:00:00 +0000 Full Article
z Understanding Decolonization in the 21st Century By feedproxy.google.com Published On :: Fri, 14 Feb 2020 00:00:00 +0000 Full Article
z Undercurrents: Episode 46 - Understanding Decolonization, and China’s Response to Coronavirus By feedproxy.google.com Published On :: Mon, 24 Feb 2020 00:00:00 +0000 Full Article
z Proximity Dependent Biotinylation: Key Enzymes and Adaptation to Proteomics Approaches [Reviews] By feedproxy.google.com Published On :: 2020-05-01T00:05:26-07:00 The study of protein subcellular distribution, their assembly into complexes and the set of proteins with which they interact with is essential to our understanding of fundamental biological processes. Complementary to traditional assays, proximity-dependent biotinylation (PDB) approaches coupled with mass spectrometry (such as BioID or APEX) have emerged as powerful techniques to study proximal protein interactions and the subcellular proteome in the context of living cells and organisms. Since their introduction in 2012, PDB approaches have been used in an increasing number of studies and the enzymes themselves have been subjected to intensive optimization. How these enzymes have been optimized and considerations for their use in proteomics experiments are important questions. Here, we review the structural diversity and mechanisms of the two main classes of PDB enzymes: the biotin protein ligases (BioID) and the peroxidases (APEX). We describe the engineering of these enzymes for PDB and review emerging applications, including the development of PDB for coincidence detection (split-PDB). Lastly, we briefly review enzyme selection and experimental design guidelines and reflect on the labeling chemistries and their implication for data interpretation. Full Article
z Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2 [Enzymology] By feedproxy.google.com Published On :: 2020-04-17T00:06:05-07:00 Pyruvate kinase muscle isoform 2 (PKM2) is a key glycolytic enzyme involved in ATP generation and critical for cancer metabolism. PKM2 is expressed in many human cancers and is regulated by complex mechanisms that promote tumor growth and proliferation. Therefore, it is considered an attractive therapeutic target for modulating tumor metabolism. Various stimuli allosterically regulate PKM2 by cycling it between highly active and less active states. Several small molecules activate PKM2 by binding to its intersubunit interface. Serine and cysteine serve as an activator and inhibitor of PKM2, respectively, by binding to its amino acid (AA)-binding pocket, which therefore represents a potential druggable site. Despite binding similarly to PKM2, how cysteine and serine differentially regulate this enzyme remains elusive. Using kinetic analyses, fluorescence binding, X-ray crystallography, and gel filtration experiments with asparagine, aspartate, and valine as PKM2 ligands, we examined whether the differences in the side-chain polarity of these AAs trigger distinct allosteric responses in PKM2. We found that Asn (polar) and Asp (charged) activate PKM2 and that Val (hydrophobic) inhibits it. The results also indicate that both Asn and Asp can restore the activity of Val-inhibited PKM2. AA-bound crystal structures of PKM2 displayed distinctive interactions within the binding pocket, causing unique allosteric effects in the enzyme. These structure-function analyses of AA-mediated PKM2 regulation shed light on the chemical requirements in the development of mechanism-based small-molecule modulators targeting the AA-binding pocket of PKM2 and provide broader insights into the regulatory mechanisms of complex allosteric enzymes. Full Article
z Biophysical characterization of SARAH domain-mediated multimerization of Hippo pathway complexes in Drosophila [Signal Transduction] By feedproxy.google.com Published On :: 2020-05-01T00:06:09-07:00 Hippo pathway signaling limits cell growth and proliferation and maintains the stem-cell niche. These cellular events result from the coordinated activity of a core kinase cassette that is regulated, in part, by interactions involving Hippo, Salvador, and dRassF. These interactions are mediated by a conserved coiled-coil domain, termed SARAH, in each of these proteins. SARAH domain–mediated homodimerization of Hippo kinase leads to autophosphorylation and activation. Paradoxically, SARAH domain–mediated heterodimerization between Hippo and Salvador enhances Hippo kinase activity in cells, whereas complex formation with dRassF inhibits it. To better understand the mechanism by which each complex distinctly modulates Hippo kinase and pathway activity, here we biophysically characterized the entire suite of SARAH domain–mediated complexes. We purified the three SARAH domains from Drosophila melanogaster and performed an unbiased pulldown assay to identify all possible interactions, revealing that isolated SARAH domains are sufficient to recapitulate the cellular assemblies and that Hippo is a universal binding partner. Additionally, we found that the Salvador SARAH domain homodimerizes and demonstrate that this interaction is conserved in Salvador's mammalian homolog. Using native MS, we show that each of these complexes is dimeric in solution. We also measured the stability of each SARAH domain complex, finding that despite similarities at both the sequence and structural levels, SARAH domain complexes differ in stability. The identity, stoichiometry, and stability of these interactions characterized here comprehensively reveal the nature of SARAH domain–mediated complex formation and provide mechanistic insights into how SARAH domain–mediated interactions influence Hippo pathway activity. Full Article
z Atomic force microscopy-based characterization of the interaction of PriA helicase with stalled DNA replication forks [DNA and Chromosomes] By feedproxy.google.com Published On :: 2020-05-01T00:06:09-07:00 In bacteria, the restart of stalled DNA replication forks requires the DNA helicase PriA. PriA can recognize and remodel abandoned DNA replication forks, unwind DNA in the 3'-to-5' direction, and facilitate the loading of the helicase DnaB onto the DNA to restart replication. Single-stranded DNA–binding protein (SSB) is typically present at the abandoned forks, but it is unclear how SSB and PriA interact, although it has been shown that the two proteins interact both physically and functionally. Here, we used atomic force microscopy to visualize the interaction of PriA with DNA substrates with or without SSB. These experiments were done in the absence of ATP to delineate the substrate recognition pattern of PriA before its ATP-catalyzed DNA-unwinding reaction. These analyses revealed that in the absence of SSB, PriA binds preferentially to a fork substrate with a gap in the leading strand. Such a preference has not been observed for 5'- and 3'-tailed duplexes, suggesting that it is the fork structure that plays an essential role in PriA's selection of DNA substrates. Furthermore, we found that in the absence of SSB, PriA binds exclusively to the fork regions of the DNA substrates. In contrast, fork-bound SSB loads PriA onto the duplex DNA arms of forks, suggesting a remodeling of PriA by SSB. We also demonstrate that the remodeling of PriA requires a functional C-terminal domain of SSB. In summary, our atomic force microscopy analyses reveal key details in the interactions between PriA and stalled DNA replication forks with or without SSB. Full Article
z Net Zero and Beyond: What Role for Bioenergy with Carbon Capture and Storage? By feedproxy.google.com Published On :: Mon, 06 Jan 2020 13:55:01 +0000 Invitation Only Research Event 23 January 2020 - 8:30am to 10:00am Chatham House | 10 St James's Square | London | SW1Y 4LE Event participants Richard King, Senior Research Fellow, Energy, Environment and Resources Department, Chatham HouseChair: Duncan Brack, Associate Fellow, Energy, Environment and Resources Department, Chatham House In the context of the feasibility of reducing greenhouse gas emissions to net zero, policymakers are beginning to pay more attention to options for removing carbon dioxide from the atmosphere. A wide range of potential carbon dioxide removal (CDR) options are currently being discussed and modelled though the most prominent among them are bioenergy with carbon capture and storage (BECCS) and afforestation and reforestation.There are many reasons to question the reliance on BECCS assumed in the models including the carbon balances achievable, its substantial needs for land, water and other inputs and technically and economically viable carbon capture and storage technologies.This meeting will examine the potentials and challenges of BECCS in the context of other CDR and emissions abatement options. It will discuss the requisite policy and regulatory frameworks to minimize sustainability and socio-political risks of CDR approaches while also avoiding overshooting climate goals.Attendance at this event is by invitation only. Event attributes Chatham House Rule Department/project Energy, Environment and Resources Programme, Sustainable Transitions Series Chloé Prendleloup Email Full Article
z Net Zero and Beyond: What Role for Bioenergy with Carbon Capture and Storage? By feedproxy.google.com Published On :: Wed, 29 Jan 2020 11:51:45 +0000 29 January 2020 Policymakers are in danger of sleepwalking into ineffective carbon dioxide removal solutions in the quest to tackle climate change. This paper warns against overreliance on bioenergy with carbon capture and storage (BECCS). Read online Download PDF Duncan Brack Associate Fellow, Energy, Environment and Resources Programme @DuncanBrack Google Scholar Richard King Senior Research Fellow, Energy, Environment and Resources Programme LinkedIn Reaching Net Zero: Does BECCS Work? Policymakers can be influenced by ineffective carbon dioxide removal solutions in the quest to tackle climate change. This animation explores the risks of using bioenergy with carbon capture and storage (BECCS). SummaryCurrent climate efforts are not progressing quickly enough to prevent the world from overshooting the global emissions targets set in the Paris Agreement; accordingly, attention is turning increasingly to options for removing carbon dioxide from the atmosphere – ‘carbon dioxide removal’ (CDR). Alongside afforestation and reforestation, the main option under discussion is bioenergy with carbon capture and storage (BECCS): processes through which the carbon emissions from burning biomass for energy are captured before release into the atmosphere and stored in underground reservoirs.This pre-eminent status is not, however, based on a comprehensive analysis of the feasibility and impacts of BECCS. In reality, BECCS has many drawbacks.Models generally assume that biomass for energy is inherently carbon-neutral (and thus that BECCS, by capturing and storing the emissions from combustion, is carbon-negative), but in reality this is not a valid assumption.On top of this, the deployment of BECCS at the scales assumed in most models would consume land on a scale comparable to half that currently taken up by global cropland, entailing massive land-use change, potentially endangering food security and biodiversity. There is also significant doubt about the likely energy output of BECCS solutions.BECCS may still have some role to play in strategies for CDR, depending mainly on the feedstock used; but it should be evaluated on the same basis as other CDR options, such as nature-based solutions or direct air carbon capture and storage (DACCS). Analysis should take full account of carbon balances over time, the requirements of each CDR option in terms of demand for land, water and other inputs, and the consequences of that demand.There is an urgent need for policymakers to engage with these debates. The danger at the moment is that policymakers are ‘sleepwalking towards BECCS’ simply because most models incorporate it – or, almost as bad, it may be that they are simply ignoring the need for any meaningful action on CDR as a whole. Department/project Energy, Environment and Resources Programme, Bioenergy, Carbon Capture and Storage (BECCS) Full Article
z Episode 21: Zero Dark Thirty & Most Anticipated of 2013 By feedproxy.google.com Published On :: Fri, 18 Jan 2013 19:17:00 +0000 Zero Dark Thirty ReviewOur Top 10 Most Anticipated Films of 2013What We Watched: Jiro: Dreams of Sushi, Take This Waltz, Futurama, The Great Happiness Space, Indie Game: The Movie, Somewhere Between, Lincoln & Chasing GhostsYou can listen to or download our episode here. (right click to save) Next Episode: Reviews of Mama and The Last StandThanks again to Jim and Patrick from The Director's Club Podcast for their support.If you'd like to check out their podcast go here: http://directorsclubpodcast.comIf you would like to read Jim's awesome blog on why he loves movie podcasts, go here: http://instantjim.com/post/40536863106/moviepodcasts2012 Full Article
z Episode 25: Oz: The Great and Powerful By feedproxy.google.com Published On :: Fri, 22 Mar 2013 07:56:00 +0000 Review of Oz: The Great and PowerfulMovie Homework: Network/CloserWhat We Watched: Dredd, Undefeated, Sassy Pants, Game of Thrones, Gummo, This is 40Download the episode here. (right click to save)Next Week's Main Review: Springbreakers Full Article
z Episode 38: Oldboy/Frozen By feedproxy.google.com Published On :: Thu, 05 Dec 2013 07:02:00 +0000 Oldboy ReviewFrozen ReviewWhat We Watched: Fargo, Homefront, GravityThe Walking Dead Mid-Season Spoiler DiscussionOldboy Spoiler DiscussionThor: The Dark World Acid-Indused Hypothesizing Download the episode here. Subscribe to us on iTunes here. Full Article
z Why is the U.S. joining Venezuela and Nicaragua in discrediting a system to protect human rights? By feedproxy.google.com Published On :: Tue, 21 Jan 2020 14:24:06 +0000 Source The Washington Post URL https://www.washingtonpost.com/opinions/2020/01/17/why-is-us-joining-venezuela-n... Release date 17 January 2020 Expert Dr Christopher Sabatini In the news type Op-ed Hide date on homepage Full Article
z Alles nur zum Schein By feedproxy.google.com Published On :: Mon, 10 Feb 2020 16:21:45 +0000 Source Der Freitaig URL https://www.freitag.de/autoren/der-freitag/alles-nur-zum-schein Release date 10 July 2019 Expert Hans Kundnani In the news type Op-ed Hide date on homepage Full Article
z The Democrats have set themselves up to fail in November's election — and they don't seem to realize it By feedproxy.google.com Published On :: Mon, 24 Feb 2020 14:52:24 +0000 Source The Independent URL https://www.independent.co.uk/voices/democrats-buttigieg-sanders-trump-biden-str... Release date 21 February 2020 Expert Dr Lindsay Newman In the news type Op-ed Hide date on homepage Full Article
z China already leads 4 of the 15 U.N. specialized agencies — and is aiming for a 5th By feedproxy.google.com Published On :: Thu, 05 Mar 2020 10:58:21 +0000 Source The Washington Post URL https://www.washingtonpost.com/politics/2020/03/03/china-already-leads-4-15-un-s... Release date 03 March 2020 Expert Courtney J. Fung In the news type Op-ed Hide date on homepage Full Article
z Regional politics of Kazakhstan in Central Asia By feedproxy.google.com Published On :: Wed, 06 May 2020 17:21:20 +0000 Source Central Asia Analytical Network URL https://caa-network.org/archives/18673 Release date 03 December 2019 Expert Annette Bohr In the news type Op-ed Hide date on homepage Full Article
z Kazakhstan: Reaching Out to Central Asian Neighbors By feedproxy.google.com Published On :: Wed, 06 May 2020 17:23:02 +0000 Source The Diplomat URL https://thediplomat.com/2019/12/kazakhstan-reaching-out-to-central-asian-neighbo... Release date 05 December 2019 Expert Annette Bohr In the news type Op-ed Hide date on homepage Full Article
z To Save the Amazon, Treat It Like a UNESCO World Heritage Site By feedproxy.google.com Published On :: Wed, 06 May 2020 17:35:30 +0000 Source World Politics Review URL https://www.worldpoliticsreview.com/articles/28620/the-solution-to-amazon-defore... Release date 23 March 2020 Expert Dr Christopher Sabatini In the news type Op-ed Hide date on homepage Full Article
z The insurgency in northern Mozambique has got worse. Why? By feedproxy.google.com Published On :: Wed, 06 May 2020 17:41:31 +0000 Source Mail & Guardian URL https://mg.co.za/article/2020-03-31-the-insurgency-in-northern-mozambique-has-go... Release date 31 March 2020 Expert Dr Alex Vines OBE In the news type Op-ed Hide date on homepage Full Article
z The single CCA-adding enzyme of T. brucei has distinct functions in the cytosol and in mitochondria [RNA] By feedproxy.google.com Published On :: 2020-05-01T00:06:09-07:00 tRNAs universally carry a CCA nucleotide triplet at their 3'-ends. In eukaryotes, the CCA is added post-transcriptionally by the CCA-adding enzyme (CAE). The mitochondrion of the parasitic protozoan Trypanosoma brucei lacks tRNA genes and therefore imports all of its tRNAs from the cytosol. This has generated interest in the tRNA modifications and their distribution in this organism, including how CCA is added to tRNAs. Here, using a BLAST search for genes encoding putative CAE proteins in T. brucei, we identified a single ORF, Tb927.9.8780, as a potential candidate. Knockdown of this putative protein, termed TbCAE, resulted in the accumulation of truncated tRNAs, abolished translation, and inhibited both total and mitochondrial CCA-adding activities, indicating that TbCAE is located both in the cytosol and mitochondrion. However, mitochondrially localized tRNAs were much less affected by the TbCAE ablation than the other tRNAs. Complementation assays revealed that the N-terminal 10 amino acids of TbCAE are dispensable for its activity and mitochondrial localization and that deletion of 10 further amino acids abolishes both. A growth arrest caused by the TbCAE knockdown was rescued by the expression of the cytosolic isoform of yeast CAE, even though it was not imported into mitochondria. This finding indicated that the yeast enzyme complements the essential function of TbCAE by adding CCA to the primary tRNA transcripts. Of note, ablation of the mitochondrial TbCAE activity, which likely has a repair function, only marginally affected growth. Full Article
z Homogenization over the spatial variable in nonlinear parabolic systems By www.ams.org Published On :: Fri, 10 Apr 2020 08:09 EDT S. A. Kashchenko Trans. Moscow Math. Soc. 80 (2020), 53-71. Abstract, references and article information Full Article
z Teste de sangue para detectar Alzheimer está próximo da realidade By saudeprospera.com.br Published On :: Mon, 30 Oct 2017 21:43:50 +0000 Exame poderá detectar a doença na fase inicial. Pesquisadores da Faculdade de Medicina Osteopática da Universidade de Rowan, nos Estados Unidos, afirmam que estão perto de desenvolver um exame de sangue para detectar Alzheimer com precisão, o que dar... The post Teste de sangue para detectar Alzheimer está próximo da realidade appeared first on Saúde Próspera. Full Article Dicas de Saúde
z Cuidados com a pele – Aprenda a fazer limpeza de pele caseira By saudeprospera.com.br Published On :: Fri, 03 Nov 2017 15:25:03 +0000 Tem tomado seus cuidados com a pele? Neste artigo vamos ensinar a fazer limpeza de pele caseira. Conhecer os benefícios para limpeza de pele. Conheça o passo a passo a… The post Cuidados com a pele – Aprenda a fazer limpeza de pele caseira appeared first on Saúde Próspera. Full Article Dicas de Saúde
z Kuznetsov’s trace formula and the Hecke eigenvalues of Maass forms By www.ams.org Published On :: Wed, 01 May 2013 13:33 EDT A. Knightly and C. Li Memoirs of the AMS 224 (2012). Abstract, references and article information Full Article
z GoDaddy – “unauthorized individual” had access to login info By feedproxy.google.com Published On :: Tue, 05 May 2020 15:53:59 +0000 Web hosting behemoth GoDaddy just filed a data breach notification with the US state of California. Full Article Data loss data breach GoDaddy
z Unending Cycles of Abuse: The Practice of Bacha Bazi in Afghanistan By feedproxy.google.com Published On :: Fri, 03 Jan 2020 12:30:01 +0000 Research Event 6 February 2020 - 6:00pm to 7:00pm Chatham House | 10 St James's Square | London | SW1Y 4LE Event participants Charu Lata Hogg, Associate Fellow, Asia-Pacific Programme, Chatham HouseHameed Hakimi, Research Associate, Asia-Pacific Programme and Europe Programme, Chatham HouseChair: Champa Patel, Head of Asia-Pacific Programme, Chatham House Afghanistan has suffered decades of armed conflict resulting in a heavily armed and militarized society involving multiple armed actors and with children being disproportionately affected by the conflict. In March 2019, the Afghanistan government criminalized the harmful practice of bacha bazi, or ‘boy play’, which triggers a range of human rights violations against boys and young men. However, recent research conducted by the All Survivors Project and Youth Health and Development Organisation demonstrates that the practice is widely prevalent due to poverty, prevailing gender norms and widespread impunity. This event will look at research that was conducted in the four provinces of Balkh, Herat, Kandahar and Kabul following interviews with over 100 key informants, 24 survivors and with 13 focus group discussions. The event will be preceded by the screening of a documentary on the practice of bacha bazi in Afghanistan which includes interviews with survivors, key government officials and NGOs. The speakers will discuss how an increase in the intensity of conflict in recent years has removed protection mechanisms and increased the vulnerability of all children to conflict-related sexual violence. Event attributes Chatham House Rule Department/project Asia-Pacific Programme, Conflict, Peace and Stability Lucy Ridout Programme Administrator, Asia-Pacific Programme +44 (0) 207 314 2761 Email Full Article
z The institutionalization of the Indo-Pacific: problems and prospects By feedproxy.google.com Published On :: Wed, 08 Jan 2020 11:49:12 +0000 8 January 2020 , Volume 96, Number 1 Read online Kai He and Huiyun Feng Although the term ‘Indo-Pacific’ has become popular in the foreign policy discourse of some countries, we have yet to see any significant institution-building in the Indo-Pacific region. Borrowing insights from functional institutionalism and political leadership studies of international regimes, we introduce a ‘leadership–institution’ model to explore the problems and prospects of institutionalizing the Indo-Pacific. Through a comparative case study of the institutionalization of the Asia–Pacific vs the Indo-Pacific, we argue that two crucial factors contributed to the slow institutionalization of the Indo-Pacific as a regional system in world politics: the lack of ideational leadership from an epistemic community and the weak executive leadership from a powerful state. While ideational leaders can help states identify and expand common interests in cooperation, executive leadership will facilitate states to overcome operational obstacles in cooperation, such as the ‘collective action’ problem and the ‘relative gains’ concern. The future of institution-building in the Indo-Pacific will depend on whether and how these two leadership roles are played by scholars and states in the region. In the conclusion, we discuss the challenges of institutionalizing the Indo-Pacific and highlight China as a wild card in the future of Indo-Pacific regionalism. Full Article
z Centralization is Hobbling China’s Response to the Coronavirus By feedproxy.google.com Published On :: Thu, 06 Feb 2020 11:10:49 +0000 6 February 2020 Dr Yu Jie Senior Research Fellow on China, Asia-Pacific Programme @yu_jiec LinkedIn The sluggish early reaction by officials should not have come as a surprise. 2020-02-06-CVT.jpg Chinese police officers wearing masks stand in front of the Tiananmen Gate on 26 January. Photo: Getty Images. The coronavirus outbreak in China poses a tremendous test for Beijing. Beyond the immediate public health crisis, the Chinese Communist Party faces a stuttering economy, growing public anger and distrust, and a potentially heavy blow to its global reputation.The hesitant early response to the outbreak sheds light on the way the Chinese bureaucracy approaches crises at a time when the party leadership is tightening control at almost all levels of society. At first, officials in Wuhan attempted to censor online discussions of the virus. This changed only after President Xi Jinping’s call for a much more robust approach was followed by a sudden increase in the state media coverage of the outbreak. There is no doubt that Xi’s intervention will greatly speed up the response to the crisis, which should be welcomed.Despite China’s experience with the SARS epidemic between 2002 and 2004, the sluggish reaction by officials in Wuhan should not have come as a surprise. The tendency among bureaucrats to play down crises is deeply entrenched. And, ironically, the party leadership’s recent push for greater bureaucratic accountability and its promise of stiffer punishment for those who take a 'do little' approach have also contributed to the habit of covering up disasters.Xi has launched an ambitious programme to reform the governance of the Communist Party and re-centralize political control. This has reinforced the tendency of officials to avoid making important decisions and instead to wait for instructions from the party leadership.For decades, local governments have made things happen in China. But with tighter regulation of lower-level bureaucrats, civil servants across the system now seem less ready, and able, to provide their input, making ineffective and even mistaken policy more likely. Explainer: Coronavirus - What You Need to Know World-renowned global health expert Professor David Heymann CBE explains the key facts and work being done on the coronavirus outbreak. Moreover, the coronavirus outbreak could not have happened at a worse time. Last year was tumultuous and saw China fighting an economic slowdown while also dealing with an increasingly hostile international environment. Now, as the authorities take steps to contain the disease, economic activity has come to a near standstill, with public transport curbed and restaurants and entertainment venues shuttered.This contrasts with SARS, when double-digit growth in gross domestic product enabled Beijing to raise government expenditure to tackle the outbreak. Today, the Chinese economy is running into some of the most difficult challenges it has faced since the global financial crisis.In response to the slowdown in growth, Beijing has adopted loose fiscal policy, with an emphasis on public investment. It also continues to push big banks to cut interest rates for individual borrowers and small businesses which were already suffering from the effects of the trade war with the US before the coronavirus struck.The outbreak should give new impetus to governments, not least those that have close economic ties with China. Being a great power with ambitions for global leadership, as well as domestic reform, is not easy. Even without multi-party elections, it involves increasing, and often uncomfortable, scrutiny. As President Xi himself has put it: the road is long and the task is weighty.This article was originally published in the Financial Times. Full Article
z How Polarized India Erupted Into Violence By feedproxy.google.com Published On :: Thu, 27 Feb 2020 13:52:32 +0000 27 February 2020 Dr Gareth Price Senior Research Fellow, Asia-Pacific Programme @DrGarethPrice Google Scholar Growing social divisions, stoked by the BJP-led government, have mixed dangerously with a slowing economy. 2020-02-27-Delhi.jpg A woman sits on the terrace of a damaged building following clashes between people supporting and opposing the amendment to India's citizenship law, in New Delhi on 27 February. Photo: Getty Images. The outbreak of communal violence in Delhi this week is the worst in India’s capital for decades. It both reflects and will reinforce India’s polarization.That polarization is between the view that India represents homogeneity, grounded on the fact that its citizens are overwhelmingly (around four-fifths) Hindu (the view of the ruling Bharatiya Janata Party [BJP] of Narendra Modi), and the alternative that India represents diversity – its population includes hundreds of millions of non-Hindus and speakers of dozens if not hundreds of different languages.India’s polarization is reflected in the reaction to the three days of violence in northeast Delhi, which left hundreds injured and, at the time of writing, 34 dead. The government and its supporters portray the protesters as almost exclusively Muslim fifth-columnists, their actions facilitated by Islamist extremists or Pakistan or even the opposition Congress Party.The alternative view is that violence has been initiated by state-supported thugs, with the police turning a blind eye. In this view the protesters reflect a broader spectrum of Indian society, with a shared aversion to communalism and a commitment to India’s secular ideals.Delhi recently held a state election, and while the BJP lost, some of the rhetoric used by its politicians was vitriolic. One compared protesters to rapists and murderers. Another led his supporters in chants of ‘shoot the nation's traitors’, referring to the protestors.In such an environment, in which Hindu vigilantes feel empowered and India’s Muslims feel defenceless, Delhi’s worst communal violence for decades erupted.Some have drawn parallels between events in Delhi with the violence in Gujarat in 2002 when at least 1,000 people – the majority Muslim – were killed. There, the accusation against Modi, then chief minister of the state, was that the state turned a blind eye to violence.In general, past outbreaks of communal violence in India have been dampened by the rapid imposition of a curfew and deployment of substantial security forces to enforce it. Such an approach was notably absent in both Gujarat and, thus far, Delhi.The BJP, emboldenedThe violence takes place in the wake of two controversial actions the BJP has taken since its re-election in 2019.First, the BJP-led government revoked the special status of the state of Jammu and Kashmir. To the BJP, the special status accorded to Jammu and Kashmir, India’s only Muslim-majority state, was simply the most egregious example of their long-held view that other parties pandered to the Muslim community.While the move gained some international criticism, the general response in India to the crackdown that followed – including the restriction of internet access and arrest of a number of politicians – was muted.Then, the government put forward the Citizenship Amendment Act (CAA).In 2013, a year before the BJP’s first term in office, India’s Supreme Court ordered that the National Register of Citizens (NRC) be updated in the northeast Indian state of Assam.Migration from what is now Bangladesh has been a contentious issue in northeast India region since colonial times and was the cause of widespread agitation, and conflict, in the region from the late 1970s.While militancy continued thereafter, tension was partly resolved by the 1985 Assam Accord, which stated that people who had moved into Assam after 1971 (after the creation of Bangladesh) should be deported. However, this provision was not acted upon until the 2013 order.In August 2019, the final NRC was published. Just under 2 million people were found to be non-citizens. A substantial proportion of these, however, appear to have been Hindus, a dilemma for the BJP.To solve this, the government put forward the CAA, under which Hindus (along with followers of several other religions) could become Indian citizens. Muslims, however, were excluded. The BJP argued that the act was a generous gesture to illegal immigrants who faced persecution in neighbouring countries, and not a discriminatory gesture.Unlike moves in Kashmir, the CAA sparked nationwide protests across India. While Assam is something of a special case, concern over the possible nationwide rollout of the CAA caused alarm. The government has recently been ambiguous over its intentions, though had earlier directed states to establish at least one detention centre.The economy, creakingThat this is all taking place during an economic slowdown provides additional cause for concern. Many of India’s long-running internal conflicts subsided in recent years as the economy grew rapidly. But for the past year and a half, growth has slowed each quarter, to just 4.5% year on year.The common assumption has been that India needs to grow at 8% to stand still, given the need to create millions of jobs. Unemployment currently stands at a 45-year high. Among 20 to 24-year olds, unemployment stands at 37%. India’s demographic dividend is being wasted.For now, India seems trapped in a self-created vicious circle. The more it focuses on social and religious division, the more its economy will suffer. And while its economy worsens, the need to double-down on division as a distraction for its underemployed young men will intensify. Full Article
z Webinar: Is It All Over For Globalization? By feedproxy.google.com Published On :: Wed, 08 Apr 2020 12:55:01 +0000 Research Event 15 April 2020 - 1:00pm to 2:00pm Event participants James Crabtree, Associate Fellow, Asia-Pacific ProgrammeWill Hutton, Political Economist; Principal, Hertford College Oxford Chair: Champa Patel, Director, Asia-Pacific Programme, Chatham House The coronavirus pandemic has led many to predict the end of globalization. Confronted with unprecedented social and economic challenges, countries are prioritizing their own citizens. Now, more than ever, international cooperation is necessary but, amidst the rise of nationalist-populist governments, global partnerships are absent or faltering. And as economies grind to a halt, so does international commerce — particularly in trade-dependent Asia, a region whose rise drove the period of 'hyper-globalization' which preceded the global financial crisis. Yet there are other possible futures too. The level of scientific collaboration and information-sharing now underway in search of a vaccine is unprecedented, and after a hesitant beginning the major powers have woken up to the importance of concerted economic stimuli. The virus may in some ways have the paradoxical result of bringing countries together, not driving them apart. Rather than causing its demise, it could help begin a new period in which globalization is not as deep, but at least is better managed and more equitable? Could this be the catalyst for a new coming together at home and abroad?In this webinar, speakers debate what impact the COVID-19 pandemic will have on the future of globalization, both in Asia and around the world. Department/project Asia-Pacific Programme, Geopolitics and Governance, Sustainable and Inclusive Growth, Technology and Society, Trade, Investment and Economics Lucy Ridout Programme Administrator, Asia-Pacific Programme +44 (0) 207 314 2761 Email Full Article
z Revolutionizing and Industry By www.ams.org Published On :: Mon, 17 Sep 2018 14:03:51 -0400 Researchers: Christopher Brinton, Zoomi, Inc. and Princeton University, and Mung Chiang, Purdue University Moment: http://www.ams.org/samplings/mathmoments/mm139-netflix.pdf Description: Christopher Brinton and Mung Chiang talk about the Netflix Prize competition. Full Article
z euromicron involved in modernizing the campus of Kiel University By www.euromicron.de Published On :: Wed, 18 Sep 2019 10:03:00 +0200 ssm euromicron GmbH, a system house subsidiary of euromicron AG, is involved in a project to provide the technical equipment for the new building for the Institute of Geosciences at Kiel’s Christian Albrechts University. The seven-story new building is part of a campus-wide modernization initiative that is one of the largest public high-rise projects in the federal state of Schleswig-Holstein. Full Article
z Citizen science project aims to reveal secret life of bees By www.edp24.co.uk Published On :: Thu, 30 Apr 2020 00:00:00 GMT In these unprecedented times, we are all spending much more time at home and in our gardens. And, now that spring has well and truly arrived, it's the perfect time to get reacquainted with one of our country's busiest workers - the bee. Full Article
z 'Sweet City': the Costa Rica suburb that gave citizenship to bees, plants and trees By www.theguardian.com Published On :: Thu, 30 Apr 2020 00:00:00 GMT "Pollinators were the key," says Edgar Mora, reflecting on the decision to recognise every bee, bat, hummingbird and butterfly as a citizen of Curridabat during his 12-year spell as mayor. Full Article
z Internationalizing the Crisis By www8.gsb.columbia.edu Published On :: Mon, 06 Apr 2020 00:00:00 -0400 Global action is also a matter of self-interest for developed economies. Full Article
z My Domain is not being recognized by website By forums.digitalpoint.com Published On :: Fri, 08 May 2020 18:41:46 +0000 Full Article
z Press Release: Largest international gathering on Biosafety meets in Bonn to finalize arrangements for the Cartagena Protocol. By www.cbd.int Published On :: Wed, 18 Jun 2008 00:00:00 GMT Full Article
z Report of the Fifth Coordination Meeting for Governments and Organizations Implementing or Funding Biosafety Capacity-building Activities. By www.cbd.int Published On :: Wed, 07 Oct 2009 00:00:00 GMT Full Article