The rainbow eucalyptus may look like a digital rendering of a kid’s drawing, but it’s 100% real. These trees (also known as rainbow gum, Mindanao gum, and Eucalyptus deglupta) have brown bark that peels away, revealing layers of color across the ROYGBIV spectrum.Rainbow eucalyptus are native to Indonesia, Papua New Guinea, and the Philippines, but you can also find them in the United States, in places including Hawaii, Florida, and San Diego. READ MORE...

Hey PotterCast fans! We're back with an all new episode, as well as an all new website! What do you think?? This episode features some of the latest in Harry Potter news, a run down of all the new features of PotterCast.com, as well as some teasers for some new Leaky features coming in the next couple of weeks!

Episode 224 — From Infinitus and Beyond!

Find the latest episode and explore PotterCast interviews, discussions and more at PotterCast.com

Visit the-leaky-cauldron.org for the latest and greatest from Harry Potter's Wizard World.

Current status: no power at home, so an early dinner out with David instead of our planned cooking. https://ift.tt/2T0Cx3j

With the the 52nd annual Idaho Potato Conference and Ag Expo in Pocatello serving as a backdrop, Idaho Congressman Mike Simpson, U.S.

I am running out of adjectives to use as every where I go is totally beautiful gorgeous and stupendous. Since leaving Milan we have based ourselves in Siena and done day trips from here. We have been to Florence and San Gimmiano as well as exploring Siena

This crustacean-like critter stalked the seas half a billion years ago.

Alex Caruso and the Lakers were enjoying a dream season until the coronavirus pandemic halted play. He's hoping to get back on the court to pursue a championship.

Connor Justus' single lifted the Angels into a tie with the Diamondbacks in Tempe, Ariz; Julio Teheran and Patrick Sandoval each worked three innings.

Major League Baseball teams agree to contribute $1 million each toward a fund that will assist ballpark workers during the suspended season.

The coronavirus slump prompts airlines to beef up their loyalty programs

If having facial hair means you're touching your face more often, an infectious disease expert says, 'That's not good.'

My immigrant parents lost their jobs because of COVID-19. The CARES Act won't help because they're in the U.S. illegally. At 22, I was the breadwinner.

MELANIA TRUMP may be in one of the most controversial families in the White House's history but her fashion and beauty style is almost always impeccable. But what's the secret to her thick, lustrous hair?

Anthony Joshua and Tyson Fury are within touching distance of fighting one another.

NBA commissioner Adam Silver said the league would be on hiatus at least 30 days and it's possible the league will not play again this season

Pacers President Kevin Pritchard discusses the health of his team and how they're staying prepared for the season to resume.

Oladipo: 'I can look at it like I was just getting my rhythm back or as an opportunity to rest and ... continue building strength in my tendon.'

REALTORS® Respond to EPA's Proposed WOTUS Revision

Cycling in Tuscany, Italy

TheAmateur Traveler talks to Mary Jo Manzanares about 4 of her favorite hill towns in southern Tuscany: Contignano , Montalcino, Montepulciano and Pienza. Experience the food, the wine and the slower pace of some of these hill towns.

Samuel Dagogo-Jack
Jan 1, 2002; 15:
Articles

(To watch the full media session with sign language interpretation, click here.)

Chief Executive Carrie Lam today said the prevailing chairwoman of the Legislative Council House Committee should have the responsibility and power to deal with the matters of the committee.

Mrs Lam made the statement ahead of the Executive Council meeting this morning, noting LegCo President Andrew Leung had sought advice from outside senior counsel on how to address the delay in electing the committee’s chairman.

She said the senior counsels have observed that many of the matters raised in the House Committee’s meetings by the presiding member in the past six months have been irrelevant to the purpose of electing the committee’s chairman and vice-chairman.

“The second point that the senior counsels have observed during their very detailed scrutiny of the deliberations is that there was at least one occasion on March 13 in the House Committee meeting that gave people a very clear impression that the delaying of the election by the presiding member of the House Committee was quite deliberate and deliberate for political reasons.

“And the third thing that I observed from the senior counsels’ advice is, having regard to all these circumstances, they are of the firm view - this is the word taken from the senior counsels’ statement - that the prevailing chairwoman of the House Committee should have the responsibility and the power to deal with the business of the House Committee.”

The Chief Executive added that she expects the committee’s prevailing chairwoman Starry Lee to exercise her power.

Chronic low-grade inflammation plays a central role in the pathophysiology of gestational diabetes mellitus (GDM). In order to investigate the ability of different inflammatory blood cell parameters in predicting the development of GDM and pregnancy outcomes, 258 women with GDM and 1154 women without were included in this retrospective study. First-trimester neutrophil count outperformed white blood cell (WBC) count, and neutrophil-to-lymphocyte ratio (NLR) in the predictability for GDM. Subjects were grouped based on tertiles of neutrophil count during their first-trimester pregnancy. The results showed that as the neutrophil count increased, there was a step-wise increase in GDM incidence, as well as glucose and glycosylated hemoglobin (HbA1c) level, Homeostasis Model Assessment for Insulin Resistance (HOMA-IR), macrosomia incidence and newborn weight. Neutrophil count was positively associated with pre-pregnancy Body Mass Index (BMI), HOMA-IR and newborn weight. Additionally, neutrophil count was an independent risk factor for the development of GDM, regardless of the history of GDM. Spline regression showed that there was a significant linear association between GDM incidence and continuous neutrophil count when it exceeded 5.0 x 10⁹/L. This work suggested that first-trimester neutrophil count is closely associated with the development of GDM and adverse pregnancy outcomes.

The brain mechanisms underlying the association of hyperglycemia with depressive symptoms are unknown. We hypothesized that disrupted glutamate metabolism in pregenual anterior cingulate cortex (ACC) in type 1 diabetes (T1D) without depression affects emotional processing. Using proton magnetic resonance spectroscopy (MRS), we measured glutamate concentrations in ACC and occipital cortex (OCC) in 13 T1D without major depression (HbA1c=7.1±0.7% [54±7mmol/mol]) and 11 healthy non-diabetic controls (HbA1c=5.5±0.2% [37±3mmol/mol]) during fasting euglycemia (EU) followed by a 60-minute +5.5mmol/l hyperglycemic clamp (HG). Intrinsic neuronal activity was assessed using resting-state blood oxygen level dependent functional MRI to measure the fractional amplitude of low frequency fluctuations in slow-band 4 (fALFF4). Emotional processing and depressive symptoms were assessed using emotional tasks (Emotional-Stroop, Self-Referent-Encoding-Task SRET) and clinical ratings (HAM-D, SCL-90-R), respectively. During HG, ACC glutamate increased (1.2mmol/kg, +10%, p=0.014) while ACC fALFF4 was unchanged (-0.007, -2%, p=0.449) in T1D; in contrast, glutamate was unchanged (-0.2mmol/kg, -2%, p=0.578) while fALFF4 decreased (-0.05, -13%, p=0.002) in controls. OCC glutamate and fALFF4 were unchanged in both groups. T1D had longer SRET negative-word response-times (p=0.017) and higher depression-rating scores (HAM-D p=0.020; SCL-90-R-depression p=0.008). Higher glutamate change tended to associate with longer Emotional-Stroop response-times in T1D only. Brain glutamate must be tightly controlled during hyperglycemia due to the risk for neurotoxicity with excessive levels. Results suggest that ACC glutamate control mechanisms are disrupted in T1D, which affects glutamatergic neurotransmission related to emotional or cognitive processing. Increased prefrontal glutamate during acute hyperglycemic episodes could explain our previous findings of associations between chronic hyperglycemia, cortical thinning and depressive symptoms in T1D.

We conducted a two-sample Mendelian randomisation study to investigate the causal associations of type 2 diabetes mellitus (T2DM) with risk of overall cancer and 22 site-specific cancers. Summary-level data for cancer were extracted from the Breast Cancer Association Consortium and UK Biobank. Genetic predisposition to T2DM was associated with higher odds of pancreatic, kidney, uterine and cervical cancer, lower odds of oesophageal cancer and melanoma, but not associated with 16 other site-specific cancers or overall cancer. The odds ratios (95% confidence interval) were 1.13 (1.04, 1.22), 1.08 (1.00, 1.17), 1.08 (1.01, 1.15), 1.07 (1.01, 1.15), 0.89 (0.81, 0.98), and 0.93 (0.89, 0.97) for pancreatic, kidney, uterine, cervical, and oesophageal cancer and melanoma, respectively. The association between T2DM and pancreatic cancer was also observed in a meta-analysis of this and a previous Mendelian randomisation study (odds ratio 1.08; 1.02, 1.14; p=0.009). There was limited evidence supporting causal associations between fasting glucose and cancer. Genetically predicted fasting insulin levels were positively associated with cancers of the uterus, kidney, pancreas and lung. The present study found causal detrimental effects of T2DM on several cancers. We suggested to reinforce the cancers screening in T2DM patients to enable the early detection of cancer.

Kristian Löbner
Mar 1, 2006; 55:792-797
Pathophysiology

Ralph A. DeFronzo
Apr 1, 2009; 58:773-795
Banting Lecture

In February World Health Organization (WHO) declared the microcephaly epidemic in South America an international public health emergency. Today, the US Centers for Disease Control and Prevention, the CDC, has confirmed that it’s is Zika virus which is causing that microcephaly.  The outbreak was originally spotted in Recife, in Brazil, and it’s...

Markus Tiedge
Nov 1, 1997; 46:1733-1742
Original Article

Ralph A. DeFronzo
Apr 1, 2009; 58:773-795
Banting Lecture