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Tuesday night’s results mean a million different things all of which will be considered ad nauseam in the coming weeks and years.  But not by me, at least not today.  No, today I only say what can – and must – happen in the immediate future: the Mainstream Media must begin reporting the news accurately […]

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Methods to shorten [¹⁸F]FDG Patlak PET imaging procedures ranging from 65–90 to 20–30 min after injection, using a population-averaged input function (PIF) scaled to patient-specific image-derived input function (IDIF) values, were recently evaluated. The aim of the present study was to explore the feasibility of ultrashort 10-min [¹⁸F]FDG Patlak imaging at 55–65 min after injection using a PIF combined with direct Patlak reconstructions to provide reliable quantitative accuracy of lung tumor uptake, compared with a full-duration 65-min acquisition using an IDIF. Methods: Patients underwent a 65-min dynamic PET acquisition on a long-axial-field-of-view (LAFOV) Biograph Vision Quadra PET/CT scanner. Subsequently, direct Patlak reconstructions and image-based (with reconstructed dynamic images) Patlak analyses were performed using both the IDIF (time to relative kinetic equilibrium between blood and tissue concentration (t*) = 30 min) and a scaled PIF at 30–60 min after injection. Next, direct Patlak reconstructions were performed on the system console using only the last 10 min of the acquisition, that is, from 55 to 65 min after injection, and a scaled PIF using maximum crystal ring difference settings of both 85 and 322. Tumor lesion and healthy-tissue uptake was quantified and compared between the differently obtained parametric images to assess quantitative accuracy. Results: Good agreement was obtained between direct- and image-based Patlak analyses using the IDIF (t* = 30 min) and scaled PIF at 30–60 min after injection, performed using the different approaches, with no more than 8.8% deviation in tumor influx rate value (K_i) (mean difference ranging from –0.0022 to 0.0018 mL/[min x g]). When direct Patlak reconstruction was performed on the system console, excellent agreement was found between the use of a scaled PIF at 30–60 min after injection versus 55–65 min after injection, with 2.4% deviation in tumor K_i (median difference, –0.0018 mL/[min x g]; range, –0.0047 to 0.0036 mL/[min x g]). For different maximum crystal ring difference settings using the scan time interval of 55–65 min after injection, only a 0.5% difference (median difference, 0.0000 mL/[min x g]; range, –0.0004 to 0.0013 mL/[min x g]) in tumor K_i was found. Conclusion: Ultrashort whole-body [¹⁸F]FDG Patlak imaging is feasible on an LAFOV Biograph Vision Quadra PET/CT system without loss of quantitative accuracy to assess lung tumor uptake compared with a full-duration 65-min acquisition. The ultrashort 10-min direct Patlak reconstruction with PIF allows for its implementation in clinical practice.

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Hi ,

  FIrst of all , I hope I have posted my query in the right place . I am expecting software support/suggestions for the below issue.

   I am working on LTE which use USB interface and the Host Controller is USB 2.0 . The BSP is from NXP which supports Cadence USB 3.0 Host controller and with USB 3.0 supported cadence driver.NXP had used the   USB 3.0 host controller for USB type C based device.

  Cadence USB 3.0 based device driver seems to be backward compatible for USB 2.0 host controller .Since basic LTE functionalities seems to be working fine I continued to use the same driver in Linux 4.14.62 

  But I am facing a kernel warning of unhandled interrupt and the crash log points to cdns_irq function as shown below  The crash/kerenel warning is very random and not occuring all the time.

.691533] irq 36: nobody cared (try booting with the "irqpoll" option)

[ 1.698242] CPU: 0 PID: 87 Comm: kworker/0:1 Not tainted 4.9.88 #24

[ 1.704509] Hardware name: Freescale i.MX8QXP MEK (DT)

[ 1.709659] Workqueue: pm pm_runtime_work

[ 1.713675] Call trace:

[ 1.716123] [<ffff0000080897d0>] dump_backtrace+0x0/0x1b0

[ 1.721523] [<ffff000008089994>] show_stack+0x14/0x20

[ 1.726582] [<ffff0000083daff0>] dump_stack+0x94/0xb4

[ 1.731638] [<ffff00000810f064>] __report_bad_irq+0x34/0xf0

[ 1.737212] [<ffff00000810f4ec>] note_interrupt+0x2e4/0x330

[ 1.742790] [<ffff00000810c594>] handle_irq_event_percpu+0x44/0x58

[ 1.748974] [<ffff00000810c5f0>] handle_irq_event+0x48/0x78

[ 1.754553] [<ffff0000081100a8>] handle_fasteoi_irq+0xc0/0x1b0

[ 1.760390] [<ffff00000810b584>] generic_handle_irq+0x24/0x38

[ 1.766141] [<ffff00000810bbe4>] __handle_domain_irq+0x5c/0xb8

[ 1.771979] [<ffff000008081798>] gic_handle_irq+0x70/0x15c

1.807416] 7a40: 00000000000002ba ffff80002645bf00 00000000fa83b2da 0000000001fe116e

[ 1.815252] 7a60: ffff000088bf7c47 ffffffffffffffff 00000000000003f8 ffff0000085c47b8

[ 1.823088] 7a80: 0000000000000010 ffff800026484600 0000000000000001 ffff8000266e9718

[ 1.830925] 7aa0: ffff00000b8b0008 ffff800026784280 ffff00000b8b000c ffff00000b8d8018

[ 1.838760] 7ac0: 0000000000000001 ffff000008b76000 0000000000000000 ffff800026497b20

[ 1.846596] 7ae0: ffff00000810bd24 ffff800026497b20 ffff000008851d18 0000000000000145

[ 1.854433] 7b00: ffff000008b8d6c0 ffff0000081102d8 ffffffffffffffff ffff00000810dda8

[ 1.862268] [<ffff000008082eec>] el1_irq+0xac/0x120

[ 1.867155] [<ffff000008851d18>] _raw_spin_unlock_irqrestore+0x18/0x48

[ 1.873684] [<ffff00000810bd24>] __irq_put_desc_unlock+0x1c/0x48

[ 1.879695] [<ffff00000810de10>] enable_irq+0x48/0x70

[ 1.884756] [<ffff0000085ba8f8>] cdns3_enter_suspend+0x1f0/0x440

[ 1.890764] [<ffff0000085baca0>] cdns3_runtime_suspend+0x48/0x88

[ 1.896776] [<ffff0000084cf398>] pm_generic_runtime_suspend+0x28/0x40

[ 1.903223] [<ffff0000084dc3e8>] genpd_runtime_suspend+0x88/0x1d8

[ 1.909320] [<ffff0000084d0e08>] __rpm_callback+0x70/0x98

[ 1.914724] [<ffff0000084d0e50>] rpm_callback+0x20/0x88

[ 1.919954] [<ffff0000084d1b2c>] rpm_suspend+0xf4/0x4c8

[ 1.925184] [<ffff0000084d20fc>] rpm_idle+0x124/0x168

[ 1.930240] [<ffff0000084d26c0>] pm_runtime_work+0xa0/0xb8

[ 1.935732] [<ffff0000080dc1dc>] process_one_work+0x1dc/0x380

[ 1.941481] [<ffff0000080dc3c8>] worker_thread+0x48/0x4d0

[ 1.946885] [<ffff0000080e2408>] kthread+0xf8/0x100
[ 1.957080] handlers:

[ 1.959350] [<ffff0000085ba668>] cdns3_irq

[ 1.963449] Disabling IRQ #36

 Kindly provide a solution to solve this issue.

Thanks & Regards,

Anjali

When analyzing multiple sessions simultaneously Verisium Manager crashed and reported below error messages:

# A fatal error has been detected by the Java Runtime Environment:
#
#  SIGSEGV (0xb) at pc=0x00007efc52861b74, pid=14182, tid=18380
#
# JRE version: OpenJDK Runtime Environment Temurin-17.0.3+7 (17.0.3+7) (build 17.0.3+7)
# Java VM: OpenJDK 64-Bit Server VM Temurin-17.0.3+7 (17.0.3+7, mixed mode, sharing, tiered, compressed oops, compressed class ptrs, g1 gc, linux-amd64)
# Problematic frame:
# C  [libucis.so+0x238b74]

......

For more details please refer to the attached log file "hs_err_pid21143.log".

Two approaches were tried to solve this problem but neither has worked.
Method.1:

Setting larger heap size of Java process by "-memlimit" options.For example "vmanager -memlimit 8G".

Method.2:

Enlarging stack memory size limit of the Coverage engine by setting "IMC_NATIVE_STACKSIZE" environment variable to a larger value. For example "setenv IMC_NATIVE_STACKSIZE 1024000"

According to "hs_err_pid*.log" it is almost certain that the memory overflow triggered Java's CrashOnOutOfMemoryError and caused Verisium Manager to crash. There are some arguments about memory management of Java like "Xms, Xmx, ThreadStackSize, Xss5048k etc" and maybe this problem can be fixed by setting these arguments during analysis. However, how exactly does Verisium Manager specify these arguments during analysis? I tried to set them by the form of setting environment variables before analysis but it didn't work in analysis and their values didn't change.

Is there something wrong with my operation or is there a better solution?

Thank you very much.