Used in the plastics industry, thermoplastic injection molding machines “produce molded plastic parts by converting plastic pellets into molten material, injecting the molten plastic into a mold and cooling the plastic material,” OSHA says. Industries that use these machines include toy, medical device and beverage container manufacturers.

Nail guns are helpful tools, but they also have the potential to cause injury. NIOSH notes that nail gun injuries result in an estimated 37,000 emergency department visits every year, with 68 percent of these visits involving workers.

Washington – A group of safety advocates is calling for forward collision avoidance and mitigation braking systems, or F-CAM, to be required in all trucks and buses to help prevent deadly rear-end crashes.

Severed fingers and toes are injuries commonly associated with using truck liftgates. So are crushed feet.

Anyone working outdoors is at risk of exposure to poisonous plants, including poison ivy, poison oak and poison sumac.

Outdoor workers occasionally encounter animals when they’re on the job. The Humane Society and U.S. Postal Service provide guidelines on how to avoid dog attacks and bites.

Outdoor workers are unique in that they regularly share their workspaces with wasps, bees, hornets and other stinging insects. It’s important for workers to know how to respond to and treat stings, especially because some people may be allergic.

Download a new white paper featuring valuable tips and insights from J. J. Keller’s experts to ensure your OSHA training program is effective and compliant. Learn how to identify your training needs, avoid common missteps and more.

As winter approaches, one thing outdoor workers should know about is the “cold stress equation.” According to OSHA, low temperatures plus wind speed and wetness equals injuries and illnesses.

Stockholm – Working in the cold increases the risk of developing rheumatoid arthritis, according to researchers at the Karolinska Institute.

You may not know the name for it, but if you drive at night, you’ve probably experienced situational night blindness. It can occur “when you are temporarily blinded by a bright light such as an oncoming car’s headlights,” the Texas Department of Insurance says.

Shift work may be a fact of life for many U.S. workers, but the Ohio Bureau of Workers’ Compensation warns that such work can have serious repercussions.

Opioid use disorder is defined by Johns Hopkins Medicine as a medical condition in which you’re unable to abstain from using opioids, and behaviors centered around opioid use that interfere with daily life.

From the blare of a forklift-collision warning to the wail of an ambulance siren, noise can make us aware of hazards our eyes haven’t yet seen. But not all noise is helpful.

More than 51,000 luggage-related injuries were treated in doctors’ offices, clinics and emergency rooms in 2005, according to the American Academy of Orthopaedic Surgeons

Exposure to vibration or being required to make repetitive motions can lead to significant wear and tear on the body. The resulting injuries are known as cumulative trauma disorders.

Frequently using a computer may cause ergonomics issues, warns the Rosemont, IL-based American Academy of Orthopaedic Surgeons.

Musculoskeletal disorders such as carpal tunnel syndrome, tendinitis, muscle strains and lower back injuries affect the muscles, nerves, blood vessels, ligaments and tendons, according to OSHA. But practicing good ergonomics can help prevent workers from acquiring MSDs.

Bilbao, Spain — Promoting good musculoskeletal health among remote workers and their employers is the goal of a new fact sheet from the European Agency for Safety and Health at Work, also known as EU-OSHA.

One way to prevent becoming ill with the influenza virus is to avoid crowded settings and exposure to others who may be infected.

San Diego — Opioid use related to workers’ compensation claims decreased nearly 10% in 2023, marking one of the largest drops the workers’ comp industry has seen in years, according to a new report.

Washington — Employers can help prevent opioid use disorder among mine workers through a series of strategies, the Mine Safety and Health Administration and NIOSH emphasize in a new resource guide.

Advanced is a proven telematics system to help fleet owners manage access to equipment via radio-frequency identification or a personal identification number. Only trained operators can log in to the equipment. Once logged in, a safety checklist is presented and must be completed to use the equipment.

Gums and hydrocolloids are a diverse collection of polysaccharides that create gel-like formations when in contact with moisture. They are extremely versatile, improving texture, mouthfeel, and physical appearance in foods and beverages. Gums can be used to increase viscosity levels or benefit flow. They are especially prized for increasing stability in an ingredient matrix.

Although there may be a pandemic-related slowdown, there’s no stopping new product development targeted at the commercial and non-commercial foodservice sectors. To better help its readers with new product development strategy, Prepared Foods asked Jeff Miller, founder and CEO of Cutting Edge Innovation, to create a thought leadership series connecting R&D strategy to foodservice sales. Cutting Edge Innovation advises on foodservice strategy, sales, business development, and innovation and Miller also created an online course, “Turbocharge Your Foodservice Sales.” 

I am finding some of my aging family members are increasingly in need of guardrails where their Android phones and tablets are concerned as they keep downloading shady apps and falling for fake virus ads and fake shopify hosted stores that pollute...

A couple of my family members were shutout of their online banking last week when their bank dropped support Android 11 and earlier, their Moto One Action devices are stranded at Android 11. Neither are particularly demanding users and use little...

I have no Apple device and only have an Android phone; can I use an Aoole Air tag to track my checked airline luggage?

A wide variety of machines can help ensure that foreign matter doesn't slip into your product.

Proper water management can help avoid failure with the installation of tile or natural stone on an exterior roof deck or balcony.

Publication date: October 2024 Source: Journal of Contextual Behavioral Science, Volume 34 Author(s): Sunkyung Yoon, Sooyeon Kim, Sinhae Cho, Hyewon Choi Read the full article ›

The post Avoiding the unwanted: A cross-cultural comprehensive analysis of experiential avoidance and a meta-analysis was curated by information for practice.

Suchi Reddy curates an exhibition celebrating Indian embroidery at Salon Design, Crafting Topographies, in collaboration with Morii Design.

Nordic Studies on Alcohol and Drugs, Ahead of Print. Aims: Opioid addiction is a common problem among prisoners. The aim of this study was to examine differences between people who are incarcerated receiving opioid substitution treatment (OST) and those not receiving OST on addiction-related outcome variables during incarceration and after release from prison. Variables covered […]

The post Opioid substitution treatment, relapse and addiction-related outcomes in prison setting and after release: A longitudinal study was curated by information for practice.

The post Functional Connectivity Alterations in Suicidal Patients Among Opioid Users was curated by information for practice.

Scam artists often follow a large storm or disaster. The Texas Department of Insurance (TDI) has tips to help recognize and avoid common contracting scams.

Boston Dynamics presented the new robot. The company refused from the old hydraulic platform to introduce the new electric one under the same name, Atlas. The new robot is completely electronic, there are no hydraulic systems involved. The new robot will be stronger and more maneuverable as all developments of the previous generation of the robot will be improved. The company is ambitious to introduce humanoid robots and create infrastructure for them, including software.

Starting this autumn, the operating system on the handheld series from DENSO, member of the Toyota Group, will be Android 13.

Getac has introduced the AI-ready ZX80, a brand new 8-inch fully rugged tablet, powered by the versatile Android operating system.

Datalogic, the global provider of automatic data capture and industrial automation solutions, has announced that the Memor 30/35 has been officially certified as a rugged device under the prestigious Android Enterprise Recommended (AER) program, meeting and surpassing key standards set by Android.

Temu, the ultra-affordable online marketplace taking social media by storm, is having a huge moment. But while it’s become the go-to spot for incredible deals, the retail site is also a magnet for scammers looking to cash in on the buzz.

A reliable `in situ' method for wavefront sensing in the soft X-ray domain is reported, developed for the characterization of rotationally symmetric optical elements, like an ellipsoidal mirror shell. In a laboratory setup, the mirror sample is irradiated by an electron-excited (4.4 keV), micrometre-sized (∼2 µm) fluorescence source (carbon Kα, 277 eV). Substantially, the three-dimensional intensity distribution I(r) is recorded by a CCD camera (2048 × 512 pixels of 13.5 µm) at two positions along the optical axis, symmetrically displaced by ±21–25% from the focus. The transport-of-intensity equation is interpreted in a geometrical sense from plane to plane and implemented as a ray tracing code, to retrieve the phase Φ(r) from the radial intensity gradient on a sub-pixel scale. For reasons of statistical reliability, five intra-/extra-focal CCD image pairs are evaluated and averaged to an annular two-dimensional map of the wavefront error {cal W}. In units of the test wavelength (C Kα), an r.m.s. value sigma_{cal{W}} = ±10.9λ0 and a peak-to-valley amplitude of ±31.3λ0 are obtained. By means of the wavefront, the focus is first reconstructed with a result for its diameter of 38.4 µm, close to the direct experimental observation of 39.4 µm (FWHM). Secondly, figure and slope errors of the ellipsoid are characterized with an average of ±1.14 µm and ±8.8 arcsec (r.m.s.), respectively, the latter in reasonable agreement with the measured focal intensity distribution. The findings enable, amongst others, the precise alignment of axisymmetric X-ray mirrors or the design of a wavefront corrector for high-resolution X-ray science.

Mevalonate kinase is central to the isoprenoid biosynthesis pathway. Here, high-resolution X-ray crystal structures of two mevalonate kinases are presented: a eukaryotic protein from Ramazzottius varieornatus and an archaeal protein from Methanococcoides burtonii. Both enzymes possess the highly conserved motifs of the GHMP enzyme superfamily, with notable differences between the two enzymes in the N-terminal part of the structures. Biochemical characterization of the two enzymes revealed major differences in their sensitivity to geranyl pyrophosphate and farnesyl pyrophosphate, and in their thermal stabilities. This work adds to the understanding of the structural basis of enzyme inhibition and thermostability in mevalonate kinases.

Radiation damage remains one of the major impediments to accurate structure solution in macromolecular crystallography. The artefacts of radiation damage can manifest as structural changes that result in incorrect biological interpretations being drawn from a model, they can reduce the resolution to which data can be collected and they can even prevent structure solution entirely. In this article, we discuss how to identify and mitigate against the effects of radiation damage at each stage in the macromolecular crystal structure-solution pipeline.

An X-ray absorption spectroscopy (XAS) electrochemical cell was used to collect high-quality XAS measurements of N-truncated Cu:amyloid-β (Cu:Aβ) samples under near-physiological conditions. N-truncated Cu:Aβ peptide complexes contribute to oxidative stress and neurotoxicity in Alzheimer's patients' brains. However, the redox properties of copper in different Aβ peptide sequences are inconsistent. Therefore, the geometry of binding sites for the copper binding in Aβ4–8/12/16 was determined using novel advanced extended X-ray absorption fine structure (EXAFS) analysis. This enables these peptides to perform redox cycles in a manner that might produce toxicity in human brains. Fluorescence XAS measurements were corrected for systematic errors including defective-pixel data, monochromator glitches and dispersion of pixel spectra. Experimental uncertainties at each data point were measured explicitly from the point-wise variance of corrected pixel measurements. The copper-binding environments of Aβ4–8/12/16 were precisely determined by fitting XAS measurements with propagated experimental uncertainties, advanced analysis and hypothesis testing, providing a mechanism to pursue many similarly complex questions in bioscience. The low-temperature XAS measurements here determine that CuII is bound to the first amino acids in the high-affinity amino-terminal copper and nickel (ATCUN) binding motif with an oxygen in a tetragonal pyramid geometry in the Aβ4–8/12/16 peptides. Room-temperature XAS electrochemical-cell measurements observe metal reduction in the Aβ4–16 peptide. Robust investigations of XAS provide structural details of CuII binding with a very different bis-His motif and a water oxygen in a quasi-tetrahedral geometry. Oxidized XAS measurements of Aβ4–12/16 imply that both CuII and CuIII are accommodated in an ATCUN-like binding site. Hypotheses for these CuI, CuII and CuIII geometries were proven and disproven using the novel data and statistical analysis including F tests. Structural parameters were determined with an accuracy some tenfold better than literature claims of past work. A new protocol was also developed using EXAFS data analysis for monitoring radiation damage. This gives a template for advanced analysis of complex biosystems.

The title compound, C16H17N3O3, is racemic as it crystallizes in a centrosymmetric space group (Poverline{1}), although the trans disposition of substituents about the central C—C bond is established. The five- and six-membered rings are oriented at a dihedral angle of 75.88 (8)°. In the crystal, N—H⋯N hydrogen bonds form chains of mol­ecules extending along the c-axis direction that are connected by inversion-related pairs of O—H⋯N into ribbons. The ribbons are linked by C—H⋯π(ring) inter­actions, forming layers parallel to the ab plane. A Hirshfeld surface analysis indicates that the most important contributions for the crystal packing are from H⋯H (45.9%), H⋯N/N⋯H (23.3%), H⋯C/C⋯H (16.2%) and H⋯O/O⋯H (12.3%) inter­actions. Hydrogen bonding and van der Waals inter­actions are the dominant inter­actions in the crystal packing. The volume of the crystal voids and the percentage of free space were calculated to be 100.94 Å3 and 13.20%, showing that there is no large cavity in the crystal packing. Evaluation of the electrostatic, dispersion and total energy frameworks indicates that the stabilization is dominated by the electrostatic energy contributions in the title compound. Moreover, the DFT-optimized structure at the B3LYP/6–311 G(d,p) level is compared with the experimentally determined mol­ecular structure in the solid state. The HOMO–LUMO behaviour was elucidated to determine the energy gap.

The in­do­line portion of the title mol­ecule, C16H13NO2, is planar. In the crystal, a layer structure is generated by C—H⋯O hydrogen bonds and C—H⋯π(ring), π-stacking and C=O⋯π(ring) inter­actions. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions for the crystal packing are from H⋯H (43.0%), H⋯C/C⋯H (25.0%) and H⋯O/O⋯H (22.8%) inter­actions. Hydrogen bonding and van der Waals inter­actions are the dominant inter­actions in the crystal packing. The volume of the crystal voids and the percentage of free space were calculated to be 120.52 Å3 and 9.64%, respectively, showing that there is no large cavity in the crystal packing. Evaluation of the electrostatic, dispersion and total energy frameworks indicate that the stabilization is dominated by the dispersion energy contributions in the title compound. Moreover, the DFT-optimized structure at the B3LYP/6-311G(d,p) level is compared with the experimentally determined mol­ecular structure in the solid state.

The crystal structure of the tetra­ethyl­ammonium salt of the non-steroidal anti-inflammatory drug nimesulide (polymorph II) (systematic name: tetra­ethyl­ammonium N-methane­sulfonyl-4-nitro-2-phen­oxy­anilinide), C8H20N+·C13H11N2O5S−, was determined using single-crystal X-ray diffraction. The title compound crystallizes in the monoclinic space group P21/c with one tetra­ethyl­ammonium cation and one nimesulide anion in the asymmetric unit. In the crystal, the ions are linked by C—H⋯N and C—H⋯O hydrogen bonds and C—H⋯π inter­actions. There are differences in the geometry of both the nimesulide anion and the tetra­ethyl­ammonium cation in polymorphs I [Rybczyńska & Sikorski (2023). Sci. Rep. 13, 17268] and II of the title compound.

In the title mol­ecule, C21H23N3O3, the imidazolidine ring slightly deviates from planarity and the morpholine ring exhibits the chair conformation. In the crystal, N—H⋯O and C—H⋯O hydrogen bonds form helical chains of mol­ecules extending parallel to the c axis that are connected by C—H⋯π(ring) inter­actions. A Hirshfeld surface analysis reveals that the most important contributions for the crystal packing are from H⋯H (55.2%), H⋯C/C⋯H (22.6%) and H⋯O/O⋯H (20.5%) inter­actions. The volume of the crystal voids and the percentage of free space were calculated to be 236.78 Å3 and 12.71%, respectively. Evaluation of the electrostatic, dispersion and total energy frameworks indicates that the stabilization is dominated by the nearly equal electrostatic and dispersion energy contributions. The DFT-optimized mol­ecular structure at the B3LYP/6-311 G(d,p) level is compared with the experimentally determined mol­ecular structure in the solid state. Moreover, the HOMO–LUMO behaviour was elucidated to determine the energy gap.

This title compound, C20H26O2, was isolated from the benzene fraction of the stem bark of Staudtia kamerunensis Warb. (Myristicaceae) using column chromatography techniques over silica gel. The compound was fully characterized by single-crystal X-ray diffraction, one and two-dimensional NMR spectroscopy, IR and MS spectrometry. The compound has two fused cyclo­hexane rings attached to a benzene ring, with a carb­oxy­lic acid on C-4. This cyclo­hexene ring has a chair conformation while the other adopts a half-chair conformation. The benzene ring is substituted with a propenyl moiety. The structure is characterized by inter­molecular O—H⋯O hydrogen bonds, two C—H⋯O intra­molecular hydrogen bonds and two C—H⋯π inter­actions. The mol­ecular structure confirms previous studies carried out by spectroscopic techniques.