After postponing the eleventh hearing into the drug-related extrajudicial killings on November 11, the House Quad Committee proceeded as initially scheduled on Wednesday, November 13.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

MANILA, Philippines — Former President Rodrigo Duterte has challenged the International Criminal Court (ICC) to immediately begin its investigation into alleged crimes against humanity committed during his administration’s anti-drug campaign, saying he might die before the probe even begins. During a House quad committee hearing on Wednesday, Gabriela Party-list Rep. Arlene Brosas asked Duterte if he would cooperate with the investigation, including that of the ICC. In response, Duterte said the ICC is welcome to start its probe as soon as tomorrow (Thursday). “ICC, Ma’am?  I am asking the ICC to hurry up, and if possible, they can come here […]...

Keep on reading: Duterte dares ICC to begin probe immediately: 'Baka mamatay na ako'

MANILA, Philippines — The excess campaign funds of then-president Rodrigo Duterte were used for the reward system of police officers during his administration’s brutal war on drugs.  Duterte himself admitted this to Santa Rosa City Rep. Dan Fernandez during the House of Representatives quad committee during its 11th probe on his controversial anti-drug campaign.  “I still remember that you mentioned na yung pera galing sa donation ng inyong campaign funds will be utilized for the reward system, that’s private money,” Fernandez said.  (I still remember you mentioned that the money from the donation for your campaign funds would be utilized […]...

Keep on reading: Excess campaign funds used for drug war reward system, Duterte admits

Karapatan said that the quadcomm hearings revealed the involvement of Duterte’s people in perpetrating human rights violations against activists and human rights defenders.

Title: In Some Patients, Hypertension Meds Raise Blood Pressure
Category: Health News
Created: 8/25/2010 4:10:00 PM
Last Editorial Review: 8/26/2010 12:00:00 AM

Title: High Blood Pressure Drugs (Hypertension)
Category: Medications
Created: 8/16/2006 12:00:00 AM
Last Editorial Review: 7/1/2022 12:00:00 AM

Pulmonary hypertension (PH) is highly prevalent in patients with interstitial lung disease (ILD) and is associated with increased morbidity and mortality. Widely available noninvasive screening tools are warranted to identify patients at risk for PH, especially severe PH, that could be managed at expert centres. This review summarises current evidence on noninvasive diagnostic modalities and prediction models for the timely detection of PH in patients with ILD. It critically evaluates these approaches and discusses future perspectives in the field. A comprehensive literature search was carried out in PubMed and Scopus, identifying 39 articles that fulfilled inclusion criteria. There is currently no single noninvasive test capable of accurately detecting and diagnosing PH in ILD patients. Estimated right ventricular pressure (RVSP) on Doppler echocardiography remains the single most predictive factor of PH, with other indirect echocardiographic markers increasing its diagnostic accuracy. However, RVSP can be difficult to estimate in patients due to suboptimal views from extensive lung disease. The majority of existing composite scores, including variables obtained from chest computed tomography, pulmonary function tests and cardiopulmonary exercise tests, were derived from retrospective studies, whilst lacking validation in external cohorts. Only two available scores, one based on a stepwise echocardiographic approach and the other on functional parameters, predicted the presence of PH with sufficient accuracy and used a validation cohort. Although several methodological limitations prohibit their generalisability, their use may help physicians to detect PH earlier. Further research on the potential of artificial intelligence may guide a more tailored approach, for timely PH diagnosis.

Chronic hypertension leads to injury and fibrosis in major organs. Fibroblast activation protein (FAP) is one of key molecules in tissue fibrosis, and ⁶⁸Ga-labeled FAP inhibitor-46 (FAPI46) PET is a recently developed method for evaluating FAP. The aim of this study was to evaluate FAP expression and fibrosis in a hypertension model and to test the feasibility of ⁶⁸Ga-FAPI46 PET in hypertension. Methods: Hypertension was induced in mice by angiotensin II infusion for 4 wk. ⁶⁸Ga-FAPI46 biodistribution studies and PET scanning were conducted at 1, 2, and 4 wk after hypertension modeling, and uptake in the major organs was measured. The FAP expression and fibrosis formation of the heart and kidney tissues were analyzed and compared with ⁶⁸Ga-FAPI46 uptake. Subgroups of the hypertension model underwent angiotensin receptor blocker administration and high-dose FAPI46 blocking, for comparison. As a preliminary human study, ⁶⁸Ga-FAPI46 PET images of lung cancer patients were analyzed and compared between hypertension and control groups. Results: Uptake of ⁶⁸Ga-FAPI46 in the heart and kidneys was significantly higher in the hypertension group than in the sham group as early as week 1 and decreased after week 2. The uptake was specifically blocked in the high-dose blocking study. Immunohistochemistry also revealed FAP expression in both heart and kidney tissues. However, overt fibrosis was observed in the heart, whereas it was absent from the kidneys. The angiotensin receptor blocker–treated group showed lower uptake in the heart and kidneys than did the hypertension group. In the pilot human study, renal uptake of ⁶⁸Ga-FAPI46 significantly differed between the hypertension and control groups. Conclusion: In hypertension, FAP expression is increased in the heart and kidneys from the early phases and decreases over time. FAP expression appears to represent fibrosis activity preceding or underlying fibrotic tissue formation. ⁶⁸Ga-FAPI46 PET has potential as an effective imaging method for evaluating FAP expression in progressive fibrosis by hypertension.

BACKGROUND AND PURPOSE:

Vertebrobasilar artery stent placement (VBS) is potentially effective in preventing recurrent posterior circulation strokes; however, the incidences of in-stent restenosis and stented-territory ischemic events based on the location of stent placement have rarely been investigated. We aimed to investigate the characteristics and prognosis of VBS between intracranial and extracranial.

BackgroundCOVID-19 pandemic restrictions may have influenced behaviours related to weight.AimTo describe patterns of weight change among adults living in England with type 2 diabetes (T2D) and/or hypertension during the pandemic.Design and settingAn observational cohort study using the routinely collected health data of approximately 40% of adults living in England, accessed through the OpenSAFELY service inside TPP.MethodClinical and sociodemographic characteristics associated with rapid weight gain (>0.5 kg/m2/year) were investigated using multivariable logistic regression.ResultsData were extracted on adults with T2D (n = 1 231 455, 43.9% female, and 76.0% White British) or hypertension (n = 3 558 405, 49.7% female, and 84.3% White British). Adults with T2D lost weight overall (median δ = −0.1 kg/m2/year [interquartile range {IQR} −0.7–0.4]). However, rapid weight gain was common (20.7%) and associated with the following: sex (male versus female: adjusted odds ratio [aOR] 0.78 [95% confidence interval {CI} = 0.77 to 0.79]); age (older age reduced odds, for example, aged 60–69 years versus 18–29 years: aOR 0.66 [95% CI = 0.61 to 0.71]); deprivation (least deprived Index of Multiple Deprivation [IMD] quintile versus most deprived IMD quintile: aOR 0.87 [95% CI = 0.85 to 0.89]); White ethnicity (Black versus White: aOR 0.95 [95% CI = 0.92 to 0.98]); mental health conditions (for example, depression: aOR 1.13 [95% CI = 1.12 to 1.15]); and diabetes treatment (non-insulin treatment versus no pharmacological treatment: aOR 0.68 [95% CI = 0.67 to 0.69]). Adults with hypertension maintained stable weight overall (median δ = 0.0 kg/m2/year [IQR −0.6–0.5]); however, rapid weight gain was common (24.7%) and associated with similar characteristics as in T2D.ConclusionAmong adults living in England with T2D and/or hypertension, rapid pandemic weight gain was more common among females, younger adults, those living in more deprived areas, and those with mental health conditions.

PURPOSE

The impact of digital health on medically underserved patients is unclear. This study aimed to determine the early impact of a digital innovation to grow quality care through an interprofessional care team (DIG IT) on the blood pressure (BP) and 10-year atherosclerotic cardiovascular disease (ASCVD) risk score of medically underserved patients.

Apr 18, 2024

The human tragedy continuing to unfold in Gaza and Israel reminds us how important it is to get strategic forecasting right. While in no way excusing Hamas’ culpability for 7 October, we also cannot dismiss the fact that the failure to anticipate and prepare for such an attack has had grave consequences for communities on both sides of this conflict, undermined efforts to bring peace and prosperity to the region, and affected global interests through the expansion of the conflict to the Red Sea and potentially beyond. 

Broll

Quéjate fuerte

Chef Giorgio Rapicavoli de Eating House Miami nos invita participar en el concurso de milk life Somos Fuertes

Jorge Narvaez habla sobre la unión y la fuerza de la familia

Anuncio de servicio público para TV :30

Arroz Con Caf� Con Leche

“Why is it that the issues that most of the public agrees with — healthcare, living wages, voting rights, democracy — why is it that those issues weren’t more up front?” We speak to Bishop William Barber about Joe Biden and Kamala Harris’s failed election campaigns, Donald Trump’s election as president and the urgent need to unite the poor and working class. Barber is the national co-chair of the Poor People’s Campaign, president and senior lecturer at Repairers of the Breach and a co-author of the book White Poverty: How Exposing Myths About Race and Class Can Reconstruct American Democracy. He urges the Democratic Party to recenter economic security and poverty alleviation in its platform and draws on historical setbacks for U.S. progressive policies to encourage voters to “get back up” and “continue to fight.”

whether it is compulsory to submit CA Certificate for refund claim exceeding Rs 200000 /- in case of GST refund due to inverted duty structure ??

Highlights: A shocking survey reveals that 101 million Indians have diabetes and 315 million suffer from hypertensi

Highlights: Five minutes of daily exercise can lower blood pressure Replacing sitting with 20-27 minutes of exer

Africa's food waste issue persists with up to 30% loss due to poor handling. IWMI's Dr. Enokenwa's works on gender-inclusive solutions for smallholders and households to reduce waste.

The post IWMI Calls for Concerted Effort to Combat Food Wastage first appeared on International Water Management Institute (IWMI).

Researchers have developed a non-invasive method to identify a possible cause of high blood pressure by drastically reducing radiation exposure, as suggested by a recent study.

Arterial stiffness increases blood pressure via an update in insulin resistance but not via an increase in body fat, a paper published in Frontiers in Cardiovascular Medicine concludes.

In mice, high blood pressure/hypertension was linked to bone loss and osteoporosis-related bone damage, according to new research presented at the American

A new study has found that 1 in 8 people aged 40 to 75 years had increased blood pressure (hypertension) in the evening that would be missed by a daytime GP appointment.

Macrophages and microglia, the immune cells of the brain were found to increase hypertension, say researchers. The immune cells encounter the endothelium,

Being overweight and obese can put kids at higher risk for high blood pressure (hypertension), reveals a new study. A Kaiser Permanente study of more

Reducing salt intake to moderate levels may lower high blood pressure (medlinkhypertension/medlink) naturally, reveals a new study. Results from

In youth and adolescents, medlinkunhealthy lifestyle habits/medlink, including obesity, lack of sleep, and the consumption of junk and processed food,

medlinkHypertension/medlink once considered a health issue mainly affecting older adults, has now emerged as a significant concern among the medlinkyounger population/medlink.

Group of international experts advocates for a crucial change in medlinkhypertension/medlink treatment guidelines, urging the inclusion of recommendations

medlinkSystolic blood pressure/medlink, representing arterial pressure during heartbeats, emerged as a pivotal predictor of medlinkstroke risk/medlink

More than 30% of adults globally suffer from hypertension, a major controllable risk factor for medlinkcardiovascular disease/medlink and mortality.

Health experts at All India Institute of Medical Sciences (AIIMS) find the early onset of medlinkhypertension/medlink among young children (!--ref1--)

Recent advancements in artificial intelligence (AI) have led to the development of a promising algorithm by Anumana, in collaboration with Janssen Research

medlinkPulmonary hypertension/medlink is a critical condition that often results in heart failure and death for many patients. In search of innovative

The risk of developing high blood pressure (medlinkhypertension/medlink) rises with increased levels of tellurium, a contaminant that enters foods through mining and manufacturing activities.

Every individual born in the country has the right to choose his religion. A person might have followed a religion by birth, but nothing can stop the person from embracing a new religion.

Berlin ; Boston : De Gruyter, [2023]

[s.l.] : Mohr Siebeck GmbH & Co. KG, 2023.

[s.l.] : Mohr Siebeck GmbH & Co. KG, 2023.

[s.l.] : Franz Steiner Verlag, 2023.

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