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Hydrogen bonding enhanced drug–polymer interaction for efficient drug loading and delivery

By pubs.rsc.org
Published On ::

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00003J, Communication
Xiaotian Qu, Junran Li, Yishu Yu, Jie Yang
A carrier design strategy of hydrogen bonding enhanced drug–carrier interaction is developed to prepare a polymeric nanomedicine with high drug loading content and superb loading efficiency as well as tunable nanostructures.
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Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy

By pubs.rsc.org
Published On ::

RSC Adv., 2024, 14,12796-12806
DOI: 10.1039/D4RA00610K, Paper
Open Access
Weiwei Ma, Qiufeng Zhao, Shilong Zhu, Xinyue Wang, Chuangchuang Zhang, Daming Ma, Na Li, Yanyan Yin
HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.
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Intercellular lipid-cored, hectorite nanoplatelet-armored pickering emulsions with enhanced transdermal delivery and epidermal hydration

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01610F, Paper
Boryeong Lee, Lakshmishri Prabakaran, Minkyoung Jang, Song Hua Xuan, Kyounghee Shin, Sung Ho Lee, Jin Woong Kim
An intercellular lipid-cored, hectorite nanoplatelet-armored Pickering emulsion system is proposed to enhance dermal penetration and moisture retention.
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Nanocrystalline alloy-mediated delivery of mosaic epitope peptides for universal influenza vaccine

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00742E, Paper
Hongyu Wang, Han Fu, Liyan Zhai, Jiaqing Le, Bohan Guo, Yuyang Zhou, Chenlin Ji, Dapeng Li, Yue Zhang
Mosaic influenza antimicrobial peptide-like epitopes (Ampitopes) co-crystalize with poly(I:C), a TLR3 agonist, into nanocrystalline vaccine, which boosts immunogenicity via multivalent toll like receptor 3 (TLR3) binding and immune activation.
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Multimodal layer-by-layer nanoparticles: a breakthrough in gene and drug delivery for osteosarcoma

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01541J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Eugenia Crisafulli, Annachiara Scalzone, Chiara Tonda-Turo, Joel Girón-Hernández, Piergiorgio Gentile
This study explored biodegradable nanoparticles for treating osteosarcoma. Co-delivery of miRNA-34a, doxorubicin, and resveratrol by LbL nanocoating enhanced apoptosis and cell disruption with promise to improve efficacy and reduce drug resistance.
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Drug-delivery and biological activity in colorectal cancer of a supramolecular porous material assembled from heptameric chromium-copper-adenine entities

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11156-11164
DOI: 10.1039/D4TB01521E, Paper
Sandra Mena-Gutiérrez, Ekain Maiza-Razkin, Jon Pascual-Colino, Marcos J. Araúzo-Bravo, Garikoitz Beobide, Oscar Castillo, Ainara Castellanos-Rubio, Daniela Gerovska, Antonio Luque, Sonia Pérez-Yáñez
Supramolecular metal-organic porous materials as drug delivery systems, modulation of the release kinetics using cholesterol as pore blocking agent and its impact on colorectal cancer cell cultures: cytotoxicity and RNA-seq transcriptomics studies.
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Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00599F, Review Article
Shikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. Varma
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
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Controlled therapeutic cholesterol delivery to cells for the proliferation and differentiation of keratinocytes

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, 12,11110-11122
DOI: 10.1039/D4TB01015A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Krzysztof Berniak, Ahmadreza Moradi, Agata Lichawska-Cieslar, Weronika Szukala, Jolanta Jura, Urszula Stachewicz
The research concept involves investigating how cholesterol endocytosis impacts cells using electrospun fibers as a carrier. We studied keratinocyte proliferation and evaluated gene expression levels for markers of early and late differentiation.
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Development of enzymatically crosslinked natural deep eutectogels: versatile gels for enhanced drug delivery

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01672F, Paper
Liane Meneses, Dimitra Antonia Bagaki, Ana Roda, Alexandre Paiva, Ana Rita C. Duarte
We propose a new injectable eutectogel prepared by enzymatic crosslinking, using NADES, betaine : glycerol (2 : 1), as solvent. The potential of using this material with improved rheological properties as drug delivery system, has also been evaluated.
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Start-ups cut out for meat delivery

By www.thehindubusinessline.com
Published On :: Sun, 28 Jan 2024 21:43:00 +0530

Backed by marquee investors, online delivery platforms sharpen knives to carve out a slice of India’s juicy meat business


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Endosomolytic Peptides Enable the Cellular Delivery of Peptide Nucleic Acids

By pubs.rsc.org
Published On ::

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC05214E, Communication
Open Access
JoLynn B. Giancola, Ronald T. Raines
Precision genetic medicine enlists antisense oligonucleotides (ASOs) to bind to nucleic acid targets important for human disease. Peptide nucleic acids (PNAs) have many desirable attributes as ASOs but lack cellular...
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Engineering biotin anchored-MWCNTs as a superb carrier for facile delivery of the potent Ru(II)-N^N scaffold in breast cancer cells

By pubs.rsc.org
Published On ::

Chem. Commun., 2024, 60,13376-13379
DOI: 10.1039/D4CC04276J, Communication
Lavanya Thilak Babu, Nilmadhab Roy, Tiasha Dasgupta, Sreejani Ghosh, Ramasamy Tamizhselvi, Priyankar Paira
This article portrays the construction of biotinylated-MWCNTs for SMVT-guided delivery of a potent Ru(II)-scaffold into MCF7 cells.
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Crafting porous nanoscaled architecture as a potential frontier for drug delivery

By pubs.rsc.org
Published On ::

Mol. Syst. Des. Eng., 2024, 9,1085-1106
DOI: 10.1039/D4ME00098F, Review Article
Koyeli Girigoswami, Pragya Pallavi, Agnishwar Girigoswami
Porous nanostructures exhibit remarkable nanoplatforms for payload delivery to diseased cells with high loading capacity, favorable release profiles, improved hemocompatibility, biocompatibility, and safe clearance after biodegradation.
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Preparation of UV-responsive hydrogels based on nanocellulose and their utilization in fungicide delivery

By pubs.rsc.org
Published On ::

Environ. Sci.: Nano, 2024, 11,1442-1451
DOI: 10.1039/D3EN00910F, Paper
Chaoqun You, Xinyue Ji, Hanchen Lin, Ning Ma, Wei Wei, Lingfeng Long, Like Ning, Fei Wang
A stimuli-responsive hydrogel for fungicide delivery based on UV-sensitive molecular (AZO)-conjunct CNCs is successfully prepared.
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Indian scientists develop method to create hydrogels to boost drug delivery

By www.newkerala.com
Published On :: Tue, 29 Oct 2024 22:12:02 +0530


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UST opens second delivery centre in Bengaluru 

By www.thehindubusinessline.com
Published On :: Tue, 05 Nov 2024 16:55:49 +0530

The new facility is located in Helios Business Park, Kadabeesanahalli


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Starship Robot Could Revolutionise Home Delivery in 2016 | WIRED Retail | WIRED

By www.wired.com
Published On :: Mon, 07 Dec 2015 06:27:27 +0000

The last mile of delivery is the most expensive; it is labour-intensive, slow and inefficient. But what if we used robots to help?


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How the Nuro Robotic Delivery Car Was Built

By www.wired.com
Published On :: Mon, 11 Jul 2022 16:00:00 +0000

If an automated car was only designed to transport goods, what would that look like? In theory, it wouldn't need windows, or steering wheels, or seats. Nuro is doing just that, they've engineered a vehicle that's sole purpose is delivering things. How did they do it? Nuro's Andrew Clare and Daniel Hundt break it all down. Producer/Director: Maya Dangerfield Director of Photography: Florian Pilsl Editor: Josh Pullar External Talent: Andrew Clare and Daniel Hundt Line Producer: Joseph Buscemi Associate Producer: Samantha Vélez Production Manager: Eric Martinez Camera Operator: Shreyans Zaveri Audio: Simon Gordon Post Production Supervisor: Doug Larsen Post Production Coordinator: Ian Bryant Supervising Editor: Doug Larsen Assistant Editor: Billy Ward


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The Future Of Delivery Is On Demand

By www.wired.com
Published On :: Wed, 02 Oct 2024 12:00:00 +0000

Branded Content by Uber Direct | With convenience becoming a top priority, consumers are increasingly demanding faster, more flexible delivery options. Discover how businesses are integrating rapid and customizable delivery solutions to keep pace with the evolving needs of their customers and maintain a competitive edge in today’s market. Paid partnership with Uber Direct.


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Andhra ties up with Meta Platforms for delivery of public services

By www.thehindubusinessline.com
Published On :: Tue, 22 Oct 2024 17:11:44 +0530

AP Minister Nara Lokesh said the move enhance the efficiency of public services


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Online food delivery to grow at 18 per cent y-o-y to ₹2-lakh crore segment by 2030

By www.thehindubusinessline.com
Published On :: Wed, 03 Jul 2024 20:53:27 +0530

Overall food services industry to grow at 10-12 per cent to about ₹9-10 lakh crore : report by Swiggy, Bain & Company


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After delivery in 10 min, Blinkit promises returns in 10 min 

By www.thehindubusinessline.com
Published On :: Thu, 17 Oct 2024 15:34:12 +0530

The service, which has been under testing in Delhi NCR, is now available in Mumbai, Bangalore, Hyderabad, and Pune, with plans for expansion to additional cities


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pH and glucose dual-responsive phenylboronic acid hydrogels for smart insulin delivery

By pubs.rsc.org
Published On ::

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM01004C, Paper
Keke Yang, Hou Bo, Dewei Ma, Mingwei Peng, Qinglong Liu, Ziwen Heng, Zhongwei Gu, Xuhan Liu, Siyuan Chen
Phenylboronic acid (PBA) is a widely exploited glucose-sensitive element for constructing glucose-responsive hydrogels to enable smart insulin delivery.
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Pickering emulsions for stimuli-responsive transdermal drug delivery: effect of rheology and microstructure on performance

By pubs.rsc.org
Published On ::

Soft Matter, 2024, 20,8621-8637
DOI: 10.1039/D4SM00993B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Simona Migliozzi, Yiting He, Maryam Parhizkar, Yang Lan, Panagiota Angeli
Elucidating the impact of microgels attributes on the microstructure, rheology and functionality of Pickering emulsions.
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Two Rajasthan youth who cheated Amazon delivery partner of ₹11.45 lakh in Mangaluru arrested

By www.thehindu.com
Published On :: Sun, 03 Nov 2024 22:22:23 +0530


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Synthesis of F127-GA@ZnO nanogel as a cisplatin drug delivery pH-sensitive system

By pubs.rsc.org
Published On ::

RSC Adv., 2024, 14,35005-35020
DOI: 10.1039/D4RA06514J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nguyen Ngoc Son, Vu Minh Thanh, Nguyen Thi Huong
In this study, a novel drug delivery system based on zinc oxide nanoparticles (ZnO NPs) was developed for the enhanced delivery of cisplatin (CPT) to improve cancer treatment.
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Enhancing skin delivery of tranexamic acid via esterification: synthesis and evaluation of alkyl ester derivatives

By pubs.rsc.org
Published On ::

RSC Adv., 2024, 14,34996-35004
DOI: 10.1039/D4RA06266C, Paper
Open Access
Yutong Zeng, Mengrui Ma, Yongfeng Chen, Huichao Xie, Pingtian Ding, Keda Zhang
An alkyl esterification prodrug strategy enhances skin penetration and deposition of tranexamic acid.
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Self-immolative polydisulfides and their use as nanoparticles for drug delivery systems

By pubs.rsc.org
Published On ::

RSC Adv., 2024, 14,35568-35577
DOI: 10.1039/D4RA07228F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katharina Völlmecke, Maurice Kramer, Corinna Horky, Oliver Dückmann, Dennis Mulac, Klaus Langer, Dirk Kuckling
Polydisulfide based nanoparticles can be degraded by glutathione (GSH) to deliver hydrophobic drugs.
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FSSAI asks States to issue SoPs for delivery personnel to ensure safe food to consumers

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 20:00:00 +0530

The directive was issued keeping in mind food safety, as peak tourist season in the country is underway


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An acidity-triggered aggregation nanoplatform based on degradable mesoporous organosilica nanoparticles for precise drug delivery and phototherapy of focal bacterial infection

By pubs.rsc.org
Published On ::

Dalton Trans., 2024, 53,17893-17901
DOI: 10.1039/D4DT02111H, Paper
Yunhan Huang, Wei Guo, Xinyu Wang, Jingrui Chang, Bo Lu
An acidity-triggered aggregation antibacterial nanoplatform based on biodegradable mesoporous organic silica nanoparticles, is reported. It enables precise drug release and spatial accuracy for photodynamic therapy and photothermal therapy.
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Food delivery agents and dependents find it hard to get insurance claims cleared

By www.thehindu.com
Published On :: Sat, 09 Nov 2024 20:22:43 +0530

Food delivery agent and their dependents have been finding it increasingly hard to get insurance claims for injuries or death caused by accidents or other reasons


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Oral delivery of electrohydrodynamically encapsulated Lactiplantibacillus plantarum CRD7 modulates gut health, antioxidant activity, and cytokines-related inflammation and immunity in mice

By pubs.rsc.org
Published On ::

Food Funct., 2024, 15,10761-10781
DOI: 10.1039/D4FO02732A, Paper
Vinay Venkatesh Varada, Sachin Kumar, Sravani Balaga, Antony Johnson Thanippilly, Heartwin A. Pushpadass, Rashmi H. M., Babu Lal Jangir, Nitin Tyagi, Ashish Kumar Samanta
The current study aimed to evaluate the effects of L. plantarum CRD7 on performance and gut health biomarkers in a Swiss albino mouse model.
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Impact of pH on the fabrication of egg white reinforced soy protein composite microgels for gastrointestinal delivery purposes

By pubs.rsc.org
Published On ::

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03997A, Paper
Feng Liu, Yi Liu, Suyun Zhang, Gang Liu, Christos Ritzoulis, Yue Zhang
Protein molecules such as soy protein isolate (SPI) and egg white (EW) are highly promising materials for developing hydrogels (especially micro/nanogels) for the encapsulation, protection and controlled release of bioactive substances.
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The rise and rise of online food delivery market

By www.thehindubusinessline.com
Published On :: Tue, 05 Nov 2024 21:44:10 +0530

The online food delivery market in India is expected to outpace the growth of the food services market itself between 2023 and 2028


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The Plight Of Food Delivery Boys

By www.rediff.com
Published On :: Wed, 12 Apr 2023 17:05:31 +0530

<em>Zwigato</em> urges viewers to think critically about the kind of unethical behaviour that food delivery workers have to put up with on a daily basis because of insensitive customers, observes Chintan Girish Modi.


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Ultra-efficient delivery of CRISPR/Cas9 using ionic liquid conjugated polymers for genome editing-based tumor therapy

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, 12,1716-1725
DOI: 10.1039/D3BM01981K, Paper
Zhongming Huang, Tongren Yang, Jie Yu, Yijian Gao, Yuhua Weng, Yuanyu Huang, Shengliang Li
Through molecular screening, ionic liquid-conjugated polymers (IL-CPs) are developed for highly efficient delivery of CRISPR/Cas9 system, which demonstrated high-performance genome editing-based tumor therapy.
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Self-assembled nanodrug delivery systems for anti-cancer drugs from traditional Chinese medicine

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, 12,1662-1692
DOI: 10.1039/D3BM01451G, Review Article
Qiao Li, Yuan Lianghao, Gao Shijie, Wang Zhiyi, Tang Yuanting, Chen Cong, Zhao Chun-Qin, Fu Xianjun
In this review, we have summarized the common self-assembled mechanism of NSMs-based SANDDSs. Meanwhile, the potential applications for cancer treatment and future development prospects are also prospected.
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Copper(II)-based metal–organic framework delivery of calcium ascorbate for enhanced chemodynamic therapy via H2O2 self-supply and glutathione depletion

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, 12,1871-1882
DOI: 10.1039/D3BM01922E, Paper
Meng Zhang, Hongjin Xue, Jiaxin Yang, Xin Zhao, Mei Xue, Wei Sun, Jianfeng Qiu, Zhihong Zhu
A Cu/ZIF-8/Vc-Ca/HA nanosystem synchronously releases Fenton catalytic Cu2+ and Vc-Ca to achieve improved chemodynamic therapy via H2O2 self-supply and GSH depletion.
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Free drug and ROS-responsive nanoparticle delivery of synergistic doxorubicin and olaparib combinations to triple negative breast cancer models

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, 12,1822-1840
DOI: 10.1039/D3BM01931D, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Robert J. Cavanagh, Patrícia F. Monteiro, Cara Moloney, Alessandra Travanut, Fatemeh Mehradnia, Vincenzo Taresco, Ruman Rahman, Stewart G. Martin, Anna M. Grabowska, Marianne B. Ashford, Cameron Alexander
Combinations of the topoisomerase II inhibitor doxorubicin and the poly (ADP-ribose) polymerase inhibitor olaparib offer potential drug–drug synergy for treatment of triple negative breast cancers (TNBC) both in free drug form and when delivered by oxidation-responsive nanoparticles.
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Self-adjuvanted L-arginine-modified dextran-based nanogels for sustained local antigenic protein delivery to antigen-presenting cells and enhanced cellular and humoral immune responses

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, 12,1771-1787
DOI: 10.1039/D3BM01150J, Paper
Jin Teng Chung, Mehrnoosh Rafiei, Ying Chau
Antigens are delivered in self-adjuvanted arginine-modified dextran-based nanogels to the dendritic cells in promoting antigen specific cellular immunity.
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Exosomes encapsulated in hydrogels for effective central nervous system drug delivery

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D3BM01055D, Review Article
Ziba Zakeri, Morteza Heiderzadeh, Azra Kocaarslan, Ecem Metin, Seyed Nasir Hosseini Karimi, Sepideh Saghati, Atay Vural, Göktuğ Akyoldaş, Kemal Baysal, Yusuf Yağcı, Yasemin Gürsoy-Özdemir, Savaş Taşoğlu, Reza Rahbarghazi, Emel Sokullu
The targeted delivery of pharmacologically active molecules, metabolites, and growth factors to the brain parenchyma has become one of the major challenges following the onset of neurodegeneration and pathological conditions.
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Nanotechnology-based delivery of therapeutics through the intranasal pathway and the blood–brain barrier for Alzheimer's disease treatment

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, 12,2007-2018
DOI: 10.1039/D3BM02003G, Review Article
Mark-Jefferson Buer Boyetey, Yonghyun Choi, Hee-Young Lee, Jonghoon Choi
Drugs for Alzheimer's disease (AD) fail to exhibit efficacy in clinical trials for a number of reasons, a major one being blood–brain barrier (BBB) permeability.
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Optimization of lipid assisted polymeric nanoparticles for siRNA delivery and cancer immunotherapy

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, 12,2057-2066
DOI: 10.1039/D3BM02071A, Paper
Song Lin, Houjin Jing, Xiaojiao Du, Xianzhu Yang, Jun Wang
A siRNA delivery system was developed using clinically approved mPEG-b-PLGA, cationic lipid and ionizable lipid for siRNA delivery and cancer immunotherapy.
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Beyond Nanoparticle-based Oral Drug Delivery: Transporter-mediated Absorption and Disease Targeting

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00313F, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Hana Cho, Kang Moo Huh, Hyun Ji Cho, Bogeon Kim, Min Suk Shim, Yong-Yeon Cho, Joo Young Lee, Hye Suk Lee, Young Jik Kwon, Han Chang Kang
Various strategies in the microscale/nanoscale have been developed to improve oral absorption of therapeutics. Among them, gastrointestinal (GI)-transporter/receptor-mediated nanosized drug delivery systems (NDDSs) have drawn attention due to their many...
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Lipid sulfoxide polymers as potential inhalable drug delivery platforms with differential albumin binding affinity

By pubs.rsc.org
Published On ::

Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D3BM02020G, Paper
Gayathri Ediriweera, Neville Butcher, Ashok Kothapalli, Jiacheng Zhao, Joanne Therese Blanchfield, Christopher N. Subasic, James Lynden Grace, Changkui Fu, Xiao Tan, John F. Quinn, David Ascher, Michael R Whittaker, Andrew Whittaker, Lisa Kaminskas
Inhalable nanomedicines are increasingly being developed to optimise the pharmaceutical treatment of respiratory diseases. Large lipid-based nanosystems at the forefront of the inhalable nanomedicines development pipeline, though, have a number...
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Meet the exosome, the rising star in drug delivery

By cen.acs.org
Published On :: 30 Jul 2018 05:00:13 +0000

Companies are hoping to use the vesicles to package small-molecule, protein, and RNA drugs or even use them as therapies themselves


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Thailand warns food delivery apps against overcharging amid COVID-19 outbreak

By www.dealstreetasia.com
Published On :: Wed, 01 Apr 2020 23:27:13 +0000

The anti-monopoly watchdog received complaints that food delivery platforms have increased their service fees for restaurants from 20% to up to 40%.

The post Thailand warns food delivery apps against overcharging amid COVID-19 outbreak appeared first on DealStreetAsia.


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Removal of goods and delivery of goods

By feedproxy.google.com
Published On :: Sun, 10 May 2020 21:26:10 GMT

What is the difference between removal of goods and delivery of goods?


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Gujarat: Five days to delivery, she kept working on

By timesofindia.indiatimes.com
Published On :: Sun, 10 May 2020 04:35:00 IST

Much before the pandemic mayhem and lockdown happened, Vanita Rathod, 32, a godown manager at Petlad town of Anand district, was sanctioned maternity leave. But first ‘janta curfew’ took place and then lockdown and Rathod saw things going beyond her personal discomfort.


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