DOI: 10.1021/acs.chemmater.9b02840

DOI: 10.1021/acs.oprd.9b00499

Biomater. Sci., 2020, 8,2255-2263
DOI: 10.1039/D0BM00069H, Paper

Liting Zhang, Chengtao Jiang, Fanjun Zeng, Haiyu Zhou, Dongdong Li, Xinyu He, Song Shen, Xianzhu Yang, Jun Wang
The cell-penetrating function of R₉ peptide of DA@R₉-NP_DOX was masked in the blood circulation, while reactivated in tumor tissue for enhanced tumor cellular uptake.
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Biomater. Sci., 2020, 8,2274-2282
DOI: 10.1039/C9BM02036E, Paper

Yue Cai, Zhuomin Xu, Qi Shuai, Fangtao Zhu, Jiao Xu, Xin Gao, Xuanrong Sun
PEG-PLA micelles are modified with F3 peptides, thus endowing the micelles with active-targeting ability due to the nucleolin-binding ability of the F3 peptides.
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Biomater. Sci., 2020, 8,2202-2211
DOI: 10.1039/C9BM01794A, Paper

Li Zhang, Shiyu Zhang, Huajian Chen, Yu Liang, Bingxia Zhao, Wanxian Luo, Qian Xiao, Jinheng Li, Junqiao Zhu, Chao Peng, Yaru Zhang, Zhe Hong, Ying Wang, Yingjia Li
Ultrasound-assisted fast extravasation and the following laser-triggered drug release of thermo-sensitive liposomes synergistically enhanced drug delivery in deep tumors.
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Biomater. Sci., 2020, 8,2318-2328
DOI: 10.1039/C9BM02000D, Paper

Bin Gao, Xiaoyu Wang, Meiyu Wang, Xiang-kui Ren, Jintang Guo, Shihai Xia, Wencheng Zhang, Yakai Feng
A dual-gene delivery system with coordinated expression function boosted the neovascularization.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00015A, Paper

Manisha Ahir, Priyanka Upadhyay, Avijit Ghosh, Sushmita Sarker, Saurav Bhattacharya, Payal Gupta, Swatilekha Ghosh, Sreya Chattopadhyay, Arghya Adhikary
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00331J, Communication

Yihang Wu, Yue Xiong, Ling Wang, Quanming Zhou, Linxian Li, Pavel A. Levkin, Gary Davidson, Liqian Gao, Wenbin Deng
A library of lipidoids self-assembling to liposomes exhibits excellent transfection efficiency in HEK 293T cells and mESCs with low cytotoxicity.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00076K, Paper

Jungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung Lee
Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00376J, Paper

Dawei Li, Jin Zhou, Mingming Zhang, Yuanzheng Ma, Yanyu Yang, Xue Han, Xing Wang
An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.
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Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01872G, Review Article

Ratchapol Jenjob, Treethip Phakkeeree, Daniel Crespy
Core–shell particles offer significant advantages in their use for bioimaging and biosensors.
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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00204F, Paper

Yongju He, Linjie Shao, Ibrahim Usman, Yao Hu, Anqiang Pan, Shuquan Liang, Hui Xu
The dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...
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Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper

Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
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Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper

Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
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Biomater. Sci., 2020, 8,2398-2403
DOI: 10.1039/C9BM01757G, Communication

Ewa Czuba-Wojnilowicz, Serena Viventi, Sara E. Howden, Simon Maksour, Amy E. Hulme, Christina Cortez-Jugo, Mirella Dottori, Frank Caruso
Multilayered particles in gene therapy for Friedreich's ataxia induce a 27 000-fold increase in frataxin gene expression in a patient-derived cell model.
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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper

Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
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Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00556H, Paper

Ana Baião, Flávia Sousa, Ana Oliveira, Carla Oliveira, Bruno Sarmento
Colorectal cancer (CRC) is one of the most incident and mortal cancers in the world, mainly due to its metastatic and metabolic ability. CD44 receptor isoform containing exon 6 (CD44v6)...
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Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10673A, Paper

Amit S. Yadav, N. Naga Venkata Radharani, Mahadeo Gorain, Anuradha Bulbule, Dattatrya Shetti, Gaurab Roy, Thejus Baby, Gopal C. Kundu
Peptide functionalized pH sensitive raloxifene-chitosan nanoparticles with high biocompatibility synergistically inhibit tumor growth and angiogenesis in breast cancer.
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Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper

Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
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Nanoscale, 2020, 12,9541-9556
DOI: 10.1039/D0NR00308E, Paper

Seyedmehdi Hossaini Nasr, Zahra Rashidijahanabad, Sherif Ramadan, Nate Kauffman, Narayanan Parameswaran, Kurt R. Zinn, Chunqi Qian, Ripla Arora, Dalen Agnew, Xuefei Huang
Atherosclerosis is associated with inflammation in the arteries. Hyaluronan atorvastatin nanoparticle conjugate could target CD44 overexpressed in atherosclerotic plaques and significantly reduce plaque associated inflammation.
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Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01792B, Paper

Tuhin Subhra Santra, Srabani Kar, Chih-Wei Chen, Jayant Borana, Te-Chang Chen, Ming-Chang Lee, Fan-Gang Tseng
Here, efficient intracellular delivery of molecules with high cell viability is reported using nanosecond-pulsed laser-activated plasmonic photoporation mediated by high-aspect-ratio nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles (nm-AuPNPs) at near-infrared wavelength. Upon...
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