break Sugarbreak: An All Natural Solution for Sugar Reduction and Healthy Blood Sugar Management By www.preparedfoods.com Published On :: Fri, 11 Sep 2020 08:00:00 -0400 Sugarbreak is empowering consumers to proactively achieve better health through a comprehensive, medical community-endorsed system that uses all natural, scientifically-proven ingredients to help manage blood sugar as part of a healthy diet and lifestyle. Full Article
break Mars Breaks Ground on Global Research and Development Hub in Chicago By www.preparedfoods.com Published On :: Tue, 21 Jun 2022 05:00:00 -0400 Mars Wrigley broke ground on a new, best-in-class, global research and development hub adjacent to the company's existing Global Innovation Center on Goose Island. Leaders from Mars as well as key Chicago stakeholders, including Michael Fassnacht, CEO, World Business Chicago, and Alderman Walter Burnett Jr., gathered together to commemorate the milestone for the company. Full Article
break Alianza Team Breaks Ground on First US Facility By www.preparedfoods.com Published On :: Mon, 28 Oct 2024 13:00:00 -0400 The blending and finishing facility is strategically positioned with nearby access to railroads and interstates for efficient truck and rail delivery across the United States. Construction is set to begin immediately. Full Article
break Ice Breakers Flavor Shifters By www.preparedfoods.com Published On :: Fri, 04 Oct 2024 08:00:00 -0400 Wild Berry to Coolmint brings together the best of both fruity and minty flavors, while Wintergreen to Coolmint offers a double hit of two popular mint flavors for the ultimate refreshing taste. Full Article
break Amy's Kitchen Breakfast Classics By www.preparedfoods.com Published On :: Thu, 17 Oct 2024 08:00:00 -0400 Amy's puts an innovative twist on morning classics, swapping eggs for their signature house-made tofu: a nutritious and protein-packed egg alternative. Full Article
break Cali Launches Shorebreak Laminate Flooring By www.floortrendsmag.com Published On :: Thu, 21 Sep 2023 07:00:00 -0400 The high-performance laminate flooring offers marble and porcelain visuals in a user-friendly, click-lock tile. Full Article
break Five Graduate from Groundbreaking Alabama Flooring Installation Course at Drake State Community & Technical College By www.floortrendsmag.com Published On :: Mon, 14 Oct 2024 15:00:00 -0400 The Floor Covering Education Foundation (FCEF), in partnership with the Alabama Community College System (ACCS) Innovation Center, Drake State Community College, and the Industry Task Force, announced the completion of its first pilot cohort for the Flooring Installation Technicians course. Full Article
break CDC: Listeria Outbreak Connected to Meat Sliced at Delis By www.foodengineeringmag.com Published On :: Mon, 22 Jul 2024 17:34:00 -0400 The agency says people sickened by listeria have recently recounted eating meat that was sliced at deli counters, including ham, turkey and liverwurst. Full Article
break FDA Investigating Salmonella Outbreak Involving Cucumbers By www.foodengineeringmag.com Published On :: Thu, 15 Aug 2024 09:58:16 -0400 Bedner Growers, Inc., of Boynton Beach, Fla., and Thomas Produce Company, of Boca Raton, Fla., are the likely sources of this outbreak, however these growers do not account for all the illnesses in the outbreak. Full Article
break Louis Dreyfus Company Breaks Ground on Ohio Soybean Processing Facility By www.foodengineeringmag.com Published On :: Mon, 01 Jul 2024 10:57:00 -0400 The new facility will boost the company’s presence in growing edible oil and animal feed markets, and will create opportunities in renewable energy feedstock markets. Full Article
break Idaho Milk Products to Break Ground on Ice Cream Facility By www.foodengineeringmag.com Published On :: Thu, 26 Sep 2024 10:00:00 -0400 Idaho Milk Products will break ground on the 183,000-sq.-ft. plant on Oct. 11. The facility will be substantially complete by early 2026 with full commercial production by May 2026. Full Article
break Yakult Breaks Ground on New Facility By www.foodengineeringmag.com Published On :: Wed, 23 Oct 2024 15:08:34 -0400 This facility is expected to begin production in 2026 and, at peak capacity, will produce 2.7 million bottles per day across six production lines. Full Article
break Boar's Head to Close Plant Due to Listeria Outbreak By www.foodengineeringmag.com Published On :: Mon, 16 Sep 2024 10:45:26 -0400 The indefinite closing of the company's Jarratt, Va., facility coincides with the company's decision to discontinue liverwurst after multiple related illnesses were linked to the product produced there. Full Article
break Breaking the child labour cycle through education: issues and impacts of the COVID-19 pandemic on children of in-country seasonal migrant workers in the brick kilns of Nepal. By ezproxy.scu.edu.au Published On :: Fri, 01 Oct 2021 00:00:00 -0400 Children's Geographies; 10/01/2021(AN 152966703); ISSN: 14733285Academic Search Premier Full Article NEPAL COVID-19 pandemic CHILD labor MIGRANT labor SEASONS COVID-19 BRICKS
break Outbreak over outbreak: children living the pandemic in the aftermath of Chile's social unrest. By ezproxy.scu.edu.au Published On :: Mon, 01 Aug 2022 00:00:00 -0400 Children's Geographies; 08/01/2022(AN 158427716); ISSN: 14733285Academic Search Premier Full Article CHILE SOCIAL unrest COVID-19 pandemic POLITICAL participation PANDEMICS SOCIAL participation COVID-19
break Not being able to fool around with my friends at break – children's home-based education in space and time. By ezproxy.scu.edu.au Published On :: Sun, 01 Oct 2023 00:00:00 -0400 Children's Geographies; 10/01/2023(AN 173035629); ISSN: 14733285Academic Search Premier Full Article HOME schooling COVID-19 pandemic SPATIAL systems ONLINE education SCHOOL closings ORPHANS
break Green versus grey break: children's place experience of recess-time in primary schools' natural and built area. By ezproxy.scu.edu.au Published On :: Thu, 01 Feb 2024 00:00:00 -0500 Children's Geographies; 02/01/2024(AN 175911758); ISSN: 14733285Academic Search Premier Full Article SCHOOL children PRIMARY schools NATURE reserves CHILDREN'S drawings CHILD behavior CURIOSITY
break Breaking the barriers: the capacity to aspire for higher education of Bangladesh tea workers' children. By ezproxy.scu.edu.au Published On :: Sat, 01 Jun 2024 00:00:00 -0400 Children's Geographies; 06/01/2024(AN 178088796); ISSN: 14733285Academic Search Premier Full Article BANGLADESH APPADURAI Arjun 1949- BOURDIEU Pierre 1930-2002 HIGHER education EMPLOYEE education CULTURAL capital TEA RURAL children SOCIAL capital
break Breaking the Gender Code: Women and Urban Public Space in the Twentieth-Century United State. By Georgina Hickey By ifp.nyu.edu Published On :: Fri, 18 Oct 2024 21:03:16 +0000 The post Breaking the Gender Code: Women and Urban Public Space in the Twentieth-Century United State. By Georgina Hickey was curated by information for practice. Full Article History
break Breaking down barriers to opportunity: Where next for Labour’s childcare offer? By ifp.nyu.edu Published On :: Wed, 09 Oct 2024 12:29:31 +0000 The post Breaking down barriers to opportunity: Where next for Labour’s childcare offer? was curated by information for practice. Full Article Video
break THE TRASH REPORT: Election Week Jitters, Celebrity Breakups, and Guerrilla Marketing Campaigns and the Basic Bitches They Work On (Me!) By www.portlandmercury.com Published On :: Mon, 04 Nov 2024 11:00:00 -0800 Worried? Try putting your head deep into this garbage gossip can for a few minutes. by Elinor Jones Hello, and welcome back to the Trash Report! Like many people with mental illness, my home is a reflection of what is happening with the ol' brain—when depression is in the driver's seat, my house gets messy; when anxiety is calling the shots, the palace is pristine. And friends, being ONE DAY away from yet ANOTHER "most crucial presidential election of our time," I am literally out of things to organize! There is no more dust. I'm ironing? Your girl is not okay. I love this column for an excuse to look at something besides another very frightening poll, so let's get to the trash! Make it Stop As this election plummets to its final resting place, Kamala Harris has collected endorsements from such luminaries as Cardi B, Bad Bunny, Eminem, Jennifer Lopez, Harrison Ford, and most of the Avengers. I do believe that, despite this, she will win https://t.co/cOU7ZeWAKa — Chase Mitchell (@ChaseMit) November 3, 2024 The most recent celebrity to come out for Trump was none other than the the famously antisemitic Mel Gibson, who shared his support only after Trump's Nazi rally at Madison Square Garden, which goes to prove just how much of a Nazi rally that definitely was. Feud Reports On a recent episode of his podcast, Ted Danson apologized to Kelsey Grammer for carrying a grudge since they worked together on Cheers. Grammer graciously accepted the apology. But I am not graciously receiving this "gossip." What happened?! What was the argument about? Why do this on a podcast without giving us the tea? This is the same kind of bullshit "this is not who we are" 2016-era dignity that no longer is the vibe. We're petty now! Tell us who was mean! Danson went on to say "I feel like I missed out on the last 30 years of Kelsey Grammer." What celebrity planet was Ted Danson living on because I feel like the rest of us have seen far too much Kelsey Grammer in the past 30 years. Streaming services were basically invented to avoid reruns of Frasier. In much more interesting feuds, Martha Stewart alluded to one between her and fellow kitchen and lifestyle guru Ina Garten. Garten had claimed in her recent memoir that the women drifted apart after one of them moved to Connecticut. Stewart agrees that the rift had to do with a move, but it was Stewart moving into a federal prison. I would imagine it could feel complicated to be a public figure being friends with a felon, but I can guarantee that if one of my friends went to jail for a non-violent crime I wouldn't stop talking to them! I'd probably talk way too much to them, in fact. I just have so many questions. If Martha Stewart and I had been friends who fell out and she later reflected on it, she would be like "Elinor was there for me when I was in jail, but she was too there for me, and wouldn't leave me alone, and I was sick of talking about prison toilet wine, so that's when our feud started." Targeted Anecdotes The long-awaited sequel to The Gladiator is coming out soon and I could not have less interest in going to see it! That is, until Pedro Pascal revealed that he and Paul Mescal kissed in one take of a fight scene, and that might be the take they used in the movie, and I guess I'm going to go see Gladiator 2 now. Have the Wicked PR folks considered floating a rumor that Cynthia Erivo and Ariana Grande kiss instead of hawking a green and pink version of every product on God's green earth? (And is there a pink earth? There probably will be soon!) At this point is there a category of merchandise that doesn’t have a Wicked tie-in? I’m half expecting my gynecologist to ask whether I want a pink or green speculum. — Anika Chapin (@AnikaChapin) October 31, 2024 Love is Dead Channing Tatum and Zoe Kravitz have allegedly called off their engagement after three years together, and just days after Tatum finally ended his years-long divorce saga with ex Jenna Dewan. This makes me think that Zoe Kravitz for sure never thought that Tatum's divorce would ever be finalized when she said yes to that ring. Tatum has been spotted around New York City smoking cigarettes, but holding them in a way that makes me think he hasn't smoked before; starting smoking at 44 is hilarious, but also very hot and chic! In other rebound choices, Gisele Bunchen revealed that she is pregnant with her third child, which will be her first since getting divorced from Tom Brady, and the first with her boyfriend, who is also her longtime Jiu-Jitsu instructor. Tom Brady is reacting to it like any normal 30-year-old woman and posting Fleetwood Mac lyrics to his Instagram which is the most I've ever liked him. On Loss in the Modern Era Helen Mirren recently waxed poetically about tragic losses of beloved icons, specifically Kurt Cobain, and specifically that Kurt Cobain's early demise in the 90s meant that he never got to experience the magic that is a GPS system. Iconic music producer Quincy Jones passed away just yesterday. He would have seen GPS. Does Helen Mirren not think this is as sad of a loss, because at least he died with the immense satisfaction of having watched a little dot that represented his car being driven towards a destination, thus making it a full and worthwhile life? Helen Mirren has yet to comment. Trash Pandas In the News A Sam's Club in Maryland had to shut down last week due to a racoon breaking into their bakery. A statement from the store read "after attempts to locate the raccoon were unsuccessful, Sam's Club representatives were advised best practices to properly capture the animal." Which means that during the initial attempts to capture the animal, they had no idea what the best practices were, and it must have been so funny. Imagine that raccoon's surprise to learn that there is a way to eat croissants, pre-trash? Going back to garbage pastries after that has got to be a bummer. Anyway, as the kids say, "in da clerb we all fam," but the clerb is a Sam's Club. Sam's Clerb, as it were. Okay, I just realized there's a bookshelf in my office that I haven't yet reorganized and if I don't do that right now it will make it so college-educated women in Michigan won't turn out in numbers, which makes a lot of sense when you think about it. I hope you get through the next few days okay. If you process stress by being around people, the Mercury is going to hold an election night party hosted by the more extroverted of us. Meanwhile, we indoor kids will be live-blogging as the night goes on, so check back here if that's something you can handle. Thank you for reading and for voting and for being cherished members of the dumpster pile. Nervously, Full Article The Trash Report
break Breakaway Illinois church agrees to pay over $1.4 million to leave UMC By www.christianpost.com Published On :: Thu, 07 Nov 2024 12:05:58 -0500 An Illinois-based congregation has agreed to pay more than $1.4 million in order to disaffiliate from The United Methodist Church following litigation over who owned its property. Full Article
break Angola: Yellow Fever outbreak spreads out of Luanda By english.pravda.ru Published On :: Wed, 30 Mar 2016 11:31:00 +0300 459 infections and 178 deaths is the latest information coming out of Angola, where an outbreak of Yellow Fever was first reported in the capital city, Luanda, in December 2015, the first outbreak of the disease in three decades, and has now spread out to ten of the country's eighteen provinces. Worse, the outbreak is reaching neighboring countries, with cases reported in the Democratic Republic of Congo, Zambia and Namibia. Other cases in Kenya and the People's Republic of China have been described as travel-related cases with links to Angola. A massive vaccination campaign was launched by the health authorities and the National Response Plan saw 87 per cent of the targeted 6.4 million people at risk vaccinated, as 7.3 million doses of the vaccine were made available with help from countries such as Brazil, the World Health Organization and the International Coordinating Group for yellow fever vaccine provision. Full Article Health
break Drama on ice: Kamila Valieva fails, Alexandra Trusova breaks down By english.pravda.ru Published On :: Thu, 17 Feb 2022 19:44:00 +0300 Kamila Valieva, Russian figure skating phenomenon, failed her performance and was ranked fourth in the free skating program at the 2022 Olympic Games in Beijing. When Kamila finished her performance, Tutberidze asked her why she stopped fighting during the performance. "Well, why did you let go of everything? Well, explain, you let go somewhere after the axel,” said the coach to her 15-year-old athlete. Full Article Sport
break Corrupt Olympic Movement is breaking wind By english.pravda.ru Published On :: Fri, 09 Feb 2018 15:30:00 +0300 The miracle did not happen. In the morning of February 9, the Court of Arbitration for Sport (CAS) announced that it was dismissing the appeals from 47 Russian athletes against the International Olympic Committee (IOC). The athletes were in a dispute regarding the decision of the IOC not to invite them to participate in the Games in Pyeongchang. The judges decided that there was nothing to abolish because the IOC did not apply sanctions against the Russians, but distributed gifts in the form of invitations instead. A nice game of words, behind which both the IOC and WADA with their dirty deeds could hide comfortably. The IOC firmly believed that only clean Russian athletes would be able to take part in the winter Olympics in Pyeongchang. However, we will see plenty of "unclean" athletes in South Korea, albeit from other countries. Suffice it to recall German biathlonist Denise Herrmann and Polish skier Poland Justyna Kowalczyk. Both of them had been caught in doping. Christopher Del Bosco of Canada will perform in ski-cross, even though his doping test showed traces of marijuana. The position of the IOC is two-faced and cynical, and its slogans about the purity of sports are needed for something else.Elite sports have been corrupt with doping for many years, and WADA would have been set up otherwise. Big sport events always mean big money involved. How easier is it for IOC and WADA officials to make champions of the people, who had their medals supported with a nice and special thank you from sponsors? Suspending competitors appears to be a great favour to do. Russia a convenient target for WADA and IOC Russia turned out to be a very convenient target. First off, Russian athletes would always win whole baskets of medals at all Olympic competitions. Secondly, Russia remains under the sanctions of Western countries, which means that no one will stand up for Russia, and we can see it with our own eyes. This is not conspiracy - this is plain business.Most importantly, one can never find the one who bears the blame. When WADA president Craig Reedie was asked whether he would like to leave his cozy office after CAS proved the innocence of the Russians, implying that WADA had soiled itself, Reedie simply said that WADA had nothing to do with it and shifted the blame for the IOC. Why is WADA so obsessed with Russian athletes only? Why not check athletes from other countries, the Norwegians, for example? Norwegians breaking doping rules The Norwegian Broadcasting Corporation (NRK), announced without any hesitation that the national team of Norway took bags of different medications for asthma to South Korea. In particular, it goes about more than 6,000 doses! There are sick athletes in other teams, but the Swedes, the Finns and the Germans hope to get by with a considerably lower amount of doses. Interestingly, journalists of Swedish SVT television channel established that since 1992, Norwegian asthmatic athletes had won every seven out of ten Olympic medals since 1992. In Russia, children with asthma are not allowed to sports training on the level of youth sports schools. It is hard to make champions out of sick children, whose lives depend on medications. One may assume that Norway has a different approach to children's sports, implicating that the Norwegians are good at bypassing anti-doping rules.At the end of last summer, Norwegian TV channel T2 aired a report, in which former skiers of the national team said that doctors had over-medicalised them with asthma medications for prophylactic purposes. It is an open secret that regular intake of such drugs contributes to muscle growth. Famous skier Martin Sundby will apparently be the first one, who will need many doses of asthma drugs in Pyeongchang. The Olympic medalist was taking the medicine for anabolic and fat burning effects.It has been 1.5 years since January 2015 till the time when Sundby was "punished" for his rampant craving for drugs. Yet, Sundby was taking medications, collecting the money and winning the medals and that his is probably proud of. He had to return some afterwards, but the most ridiculous part of the whole story is that it took CAS a whole winter to study Sundby's addiction, but the Court of Arbitration for Sport eventually suspended the Norwegian skier for two summer (!) months. How absurd is that? Full Article Sport
break Putin takes part in ceremony to launch new nuclear icebreaker By english.pravda.ru Published On :: Wed, 06 Nov 2024 17:18:00 +0300 Russian President Vladimir Putin took part in the ceremony to launch the Chukotka nuclear icebreaker built at the Baltic Shipyard in St. Petersburg. Putin participated from Moscow via video link. The footage shows the head of state giving the command "Launch cleared!" A bottle of champagne was traditionally smashed against the side of the vessel before launch. Three best workers of the Baltic Shipyard cut the detent that secured the ship to the land. The multi-ton vessel then slowly slid along the rails into the water. Full Article Russia
break The risk of breaking electronic devices rises 24% over Easter, new data reveals By www.retailtechnologyreview.com Published On :: New data has revealed that there’s a 24% rise in Brits dealing with broken laptops, tablets and phones over the Easter break each year, making it the riskiest holiday for devices. Full Article Mobile Computers Data Capture Critical Issues
break UA Little Rock Breaks $200 Million in Significant Centennial Campaign Milestone By www.newswise.com Published On :: Mon, 11 Nov 2024 10:40:39 EST The University of Arkansas at Little Rock has reached an exciting milestone in its Centennial Campaign, raising $203 million toward its overall campaign goal of $250 million by 2027. This represents the largest amount ever raised in a UA Little Rock campaign, exceeding the previous campaign by $100 million. Full Article
break Jeju City Breaks Record with 65 Tropical Nights By world.kbs.co.kr Published On :: Wed, 11 Sep 2024 13:09:56 +0900 [Science] : Jeju City experienced its 65th tropical night of the season Wednesday, setting a fresh record in an unusually hot September for the southern resort island. According to the regional office of the Korea Meteorological Administration(KMA) on Wednesday, lows for the previous night recorded 27-point-three ...[more...] Full Article Science
break Emotional Cancer Meets Free-Spirited Aquarius: Compatibility Breakdown By entertainment.howstuffworks.com Published On :: Fri, 08 Nov 2024 05:30:03 -0500 Discover the compatibility between Cancer and Aquarius in love, friendship, and relationships. Learn how their emotional and intellectual traits align or clash. Full Article
break BGS breaks ground on geothermal heating system in Keyworth HQ, UK - ThinkGeoEnergy - Geothermal Energy News By news.google.com Published On :: Tue, 05 Mar 2024 08:00:00 GMT BGS breaks ground on geothermal heating system in Keyworth HQ, UK ThinkGeoEnergy - Geothermal Energy News Full Article
break Benmont Tench - of Tom Petty and the Heartbreakers - says goodbye to John with the most Off-Rampy song ever By www.scpr.org Published On :: Wed, 28 Jun 2017 13:47:00 -0700 ; Credit: John Rabe/KPCC John Rabe | Off-Ramp®Off-Ramp fan, KPCC member (!), and Tom Petty and Heartbreakers keyboardist Benmont Tench III joined John in his old Mercedes with his large, but portable Casio. Tench has lived in the hills of Tarzana for decades, in a perfectly good house, but in the 100-degree heat, John outfitted his car with condenser mikes to record a farewell ode to Off-Ramp, Tench's "Like the Sun." The full band version of Benmont Tench III's "Like the Sun" "Like the Sun" helped Tench get back in the songwriting groove a decade ago after he burnt out on being professional songwriter in Nashville. He based the lyrics on tours of Los Angeles given to him by a friend, and takes the listener (with his Southern accent) from a restaurant called Michoacan to a hill top tent city. Tench also told John how he and his wife Alice explore Los Angeles. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
break He Inherited A Devastating Disease. A CRISPR Gene-Editing Breakthrough Stopped It By www.scpr.org Published On :: Sat, 26 Jun 2021 10:20:08 -0700 Patrick Doherty volunteered for a new medical intervention of gene-editor infusions for the treatment of genetically-based diseases.; Credit: /Patrick Doherty Rob Stein | NPRPatrick Doherty had always been very active. He trekked the Himalayas and hiked trails in Spain. But about a year and a half ago, he noticed pins and needles in his fingers and toes. His feet got cold. And then he started getting out of breath any time he walked his dog up the hills of County Donegal in Ireland where he lives. "I noticed on some of the larger hill climbs I was getting a bit breathless," says Doherty, 65. "So I realized something was wrong." Doherty found out he had a rare, but devastating inherited disease — known as transthyretin amyloidosis — that had killed his father. A misshapen protein was building up in his body, destroying important tissues, such as nerves in his hands and feet and his heart. Doherty had watched others get crippled and die difficult deaths from amyloidosis. "It's terrible prognosis," Doherty says. "This is a condition that deteriorates very rapidly. It's just dreadful." So Doherty was thrilled when he found out that doctors were testing a new way to try to treat amyloidosis. The approach used a revolutionary gene-editing technique called CRISPR, which allows scientists to make very precise changes in DNA. "I thought: Fantastic. I jumped at the opportunity," Doherty says. On Saturday, researchers reported the first data indicating that the experimental treatment worked, causing levels of the destructive protein to plummet in Doherty's body and the bodies of five other patients treated with the approach. "I feel fantastic," Doherty says. "It's just phenomenal." The advance is being hailed not just for amyloidosis patients but also as a proof-of-concept that CRISPR could be used to treat many other, much more common diseases. It's a new way of using the innovative technology. "This is a major milestone for patients," says Jennifer Doudna of the University of California, Berkeley, who shared a Nobel Prize for her work helping develop CRISPR. "While these are early data, they show us that we can overcome one of the biggest challenges with applying CRISPR clinically so far, which is being able to deliver it systemically and get it to the right place," Doudna says. CRISPR has already been shown to help patients suffering from the devastating blood disorders sickle cell disease and beta thalassemia. And doctors are trying to use it to treat cancer and to restore vision to people blinded by a rare genetic disorder. But those experiments involve taking cells out of the body, editing them in the lab, and infusing them back in or injecting CRISPR directly into cells that need fixing. The study Doherty volunteered for is the first in which doctors are simply infusing the gene-editor directly into patients and letting it find its own way to the right gene in the right cells. In this case, it's cells in the liver making the destructive protein. "This is the first example in which CRISPR-Cas9 is injected directly into the bloodstream — in other words systemic administration — where we use it as a way to reach a tissue that's far away from the site of injection and very specifically use it to edit disease-causing genes," says John Leonard, the CEO of Intellia Therapeutics, which is sponsoring the study. Doctors infused billions of microscopic structures known as nanoparticles carrying genetic instructions for the CRISPR gene-editor into four patients in London and two in New Zealand. The nanoparticles were absorbed by their livers, where they unleashed armies of CRISPR gene-editors. The CRISPR editor honed in on the target gene in the liver and sliced it, disabling production of the destructive protein. Within weeks, the levels of protein causing the disease plummeted. Researchers reported at the Peripheral Nerve Society Annual Meeting and in a paper published in The New England Journal of Medicine. "It really is exciting," says Dr. Julian Gillmore, who is leading the study at the University College London, Royal Free Hospital. "This has the potential to completely revolutionize the outcome for these patients who have lived with this disease in their family for many generations. It's decimated some families that I've been looking after. So this is amazing," Gillmore says. The patients will have to be followed longer, and more patients will have to be treated, to make sure the treatment's safe, and determine how much it's helping, Gillmore stresses. But the approach could help those struck by amyloidosis that isn't inherited, which is a far more common version of the disease, he says. Moreover, the promising results potentially open the door for using the same approach to treatment of many other, more common diseases for which taking cells out of the body or directly injecting CRISPR isn't realistic, including heart disease, muscular dystrophy and brain diseases such as Alzheimer's. "This is really opening a new era as we think about gene-editing where we can begin to think about accessing all kinds of different tissue in the body via systemic administration," Leonard says. Other scientists who are not involved in the research agree. "This is a wonderful day for the future of gene-editing as a medicine," agree Fyodor Urnov, a professor of genetics at the University of California, Berkeley. "We as a species are watching this remarkable new show called: our gene-edited future." Doherty says he started feeling better within weeks of the treatment and has continued to improve in the weeks since then. "I definitely feel better," he told NPR. "I'm speaking to you from upstairs in our house. I climbed stairs to get up here. I would have been feeling breathless. I'm thrilled." Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
break Silver Break Out Confirmed By www.streetwisereports.com Published On :: Tue, 22 Oct 2024 00:00:00 PST Source: Ron Struthers 10/22/2024 The silver break out is confirmed, and Ron Struthers of Struthers Resource Stock Report expects a move to $50. He explains why he believes Coeur Mining Inc. (CDE:NYSE) offers good value and shares one biotech stock he believes is currently a sell.Silver is up again today, currently $34.72 up about $0.64. This confirms yesterdays breakout and if you remember back in April or early May, I highlighted the breakout from a cup and handle formation and that would lead to a major upside move. This is not confirmed and I see $50 as the near term target. Similar to gold, investor participation is still quite low. Volumes into the silver etf SLF are up some but no where near 2020 volumes. There are all kinds of silver bullion available at the coin dealer I use. Our silver stocks are not dragging down the average performance of our gold stocks as much now, and I would like to add another one to the list. Coeur Mining Shares Outstanding - 399 million Coeur Mining Inc. (CDE:NYSE) has been a laggard in this bull rally thus far because it is not well understood. Investors seem to remember more of their legacy than who they are today. Many investors know Coeur as a silver company, but for many years now, most of their revenue and profits have come from gold. Around $7.20, the stock is well below its 2021 highs of around $11.50 and 2016 highs of $16 In Q2 2024, gold sales were $154.1 million, and silver sales were $67.9 million. This makes gold sales almost 70% of revenues. The stock should have responded more to the rising gold price, but as I said, I think investors were still viewing Coeur as mostly a silver company. That said, they do have large leverage to silver because their resource base they are almost 60% silver. The company is maintaining its full-year production guidance ranges of 310,000 - 355,000 gold ounces and 10.7 - 13.3 million silver ounces. Full-year CAS guidance at Palmarejo and Wharf has been reduced to reflect strong cost management efforts, while Rochester's second-half CAS guidance ranges have been increased to reflect the timing of ounces placed under leach. Other significant news on the silver front was just a couple of weeks ago, on October 4. Coeeur announced that they entered into a definitive agreement to acquire all of the issued and outstanding shares of SilverCrest pursuant to a court-approved plan of arrangement. Under the terms of the Agreement, SilverCrest shareholders will receive 1.6022 Coeur common shares for each SilverCrest common share. The Exchange Ratio implies a consideration of $11.34 per SilverCrest common share, based on the closing price of Coeur common shares on the New York Stock Exchange ("NYSE") on October 3, 2024. This represents an 18% premium based on 20-day volume-weighted average prices of Coeur and SilverCrest each as of October 3, 2024. It turns out, this was a very well timed acquisition ahead of the silver price rise and it will make Coeur the world's largest pure silver producer at about 21 million ounces per year. Their silver production should be neck and neck or just a little behind Pan American Silver not shown on this graphic. Another key positive fundamental is the expansion of their Rochester Mine this year. In mid-September, they announced that the new three-stage crushing circuit continues to deliver greatly enhanced levels of flexibility to accommodate the full range of mined ore in Rochester. For the month of August, approximately 2.7 million tons were placed on the new Stage VI leach pad, representing a 39% increase over July placement levels. Rochester remains on track to place 7.0 – 8.0 million tons per quarter during the second half of 2024 and to achieve its full-year 2024 production guidance of 4.8 – 6.6 million ounces of silver and 37,000 – 50,000 ounces of gold. Rochester is the largest open pit heap leach operation in North America and the largest silver reserve asset in the U.S. At the end of 2023, Coeur had 3.2 million ounces of proven and probable gold reserves and 243.9 million ounces of silver. At the long-term reference of 60 to 1 ratio, their reserves are 58% silver and 42% gold. With the significant expansion at Rochester and the acquisition of SilverCrest it will make a significant positive effect to increased profits and cash flow. According to Coeur's presentation, using Factset Street Research data, they will be the leader among peers. The Pro Forma adding SilverCrest is significant. The higher silver price is more gravy on top. The chart looks good, too. Volume is picking up, and it looks like the stock will break through the resistance area and head to $11. You can get some more leverage with Call options. Because this is a low-priced stock, I would take advantage of low premiums on long dates. The December 2025 $5.50 Call option is about $2.75 and is $1.87 in the money, so a premium of less than $1.00 for almost 14 months. Nektar Therapeutics (NKTR:NASDAQ) Nektar Therapeutics Recent Price - $1.41 Entry Price- $0.68 Opinion - Sell There is nothing wrong with Nektar Therapeutics (NKTR:NASDAQ), but I am concerned we could get a significant market correction, and I don't like the fact the stock has not done better in a bullish market. That said, I think this reflects how concentrated this bull market is and does not have good breadth. The stock is just below cash value but the stock is near resistance on the chart and besides that we have over 100% profits in about 8 months, lets take them. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures: Ron Struthers: I or members of my immediate household or family, own securities of: Couer Mining. I determined which companies would be included in this article based on my research and understanding of the sector. Statements and opinions expressed are the opinions of the author and not of Streetwise Reports, Street Smart, or their officers. The author is wholly responsible for the accuracy of the statements. Streetwise Reports was not paid by the author to publish or syndicate this article. Streetwise Reports requires contributing authors to disclose any shareholdings in, or economic relationships with, companies that they write about. Any disclosures from the author can be found below. Streetwise Reports relies upon the authors to accurately provide this information and Streetwise Reports has no means of verifying its accuracy. 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Struthers Resource Stock Report Disclosures All forecasts and recommendations are based on opinion. Markets change direction with consensus beliefs, which may change at any time and without notice. The author/publisher of this publication has taken every precaution to provide the most accurate information possible. The information & data were obtained from sources believed to be reliable, but because the information & data source are beyond the author's control, no representation or guarantee is made that it is complete or accurate. The reader accepts information on the condition that errors or omissions shall not be made the basis for any claim, demand or cause for action. Because of the ever-changing nature of information & statistics the author/publisher strongly encourages the reader to communicate directly with the company and/or with their personal investment adviser to obtain up to date information. Past results are not necessarily indicative of future results. Any statements non-factual in nature constitute only current opinions, which are subject to change. The author/publisher may or may not have a position in the securities and/or options relating thereto, & may make purchases and/or sales of these securities relating thereto from time to time in the open market or otherwise. Neither the information, nor opinions expressed, shall be construed as a solicitation to buy or sell any stock, futures or options contract mentioned herein. The author/publisher of this letter is not a qualified financial adviser & is not acting as such in this publication. ( Companies Mentioned: CDE:NYSE, NKTR:NASDAQ, ) Full Article
break 'We Need To Be Nurtured, Too': Many Teachers Say They're Reaching A Breaking Point By www.scpr.org Published On :: Mon, 19 Apr 2021 11:00:10 -0700 ; Credit: /Ryan Raphael for NPR Kavitha Cardoza | NPRTo say Leah Juelke is an award-winning teacher is a bit of an understatement. She was a top 10 finalist for the Global Teacher Prize in 2020; she was North Dakota's Teacher of the Year in 2018; and she was awarded an NEA Foundation award for teaching excellence in 2019. But Juelke, who teaches high school English learners in Fargo, N.D., says nothing prepared her for teaching during the pandemic. "The level of stress is exponentially higher. It's like nothing I've experienced before." It's a sentiment NPR heard from teachers across the country. After a year of uncertainty, long hours and juggling personal and work responsibilities, many told NPR they had reached a breaking point. Heidi Crumrine, a high school English teacher in Concord, N.H., says this has been the most challenging year she's ever encountered in her two decades of teaching. "And I say [that] as someone who started her first day of teaching on 9/11 in the Bronx in New York City." Teaching is one of the most stressful occupations in the U.S., tied only with nurses, a 2013 Gallup poll found. Jennifer Greif Green, an education professor at Boston University, says the additional stress teachers are reporting during the pandemic is worrying because it doesn't only affect educators — it also affects students. "The mental health and well-being of teachers can have a really important impact on the mental health and well-being of the children who they're spending most of their days with," Green explains. "Having teachers feel safe and supported in their school environments is essential to students learning and being successful." Lisa Sanetti, a professor of educational psychology at the University of Connecticut, says, "Chronically stressed teachers are just less effective in the classroom." All that stress can also lead to burnout, which leads to teachers leaving the profession, Sanetti says. "And we have a huge teacher turnover problem in our country." Districts are trying to help — with yoga classes, counseling sessions and webinars on mental health. Some teachers have organized trivia nights or online happy hours where colleagues can just vent. Teachers told NPR they force themselves to take breaks and go for a bike ride or call a friend. Some have started therapy. But most of the educators NPR spoke with say they're so exhausted, that even self-care feels like one additional thing to do. "The reality is, when you're living it, you're just trying to get to the end of the day successfully and try again tomorrow," Crumrine says. "It feels like we're building the plane while we're flying it" In March 2020, when schools moved online, teachers across the U.S. had to completely reimagine their approach to education, often with no training or time to prepare. For many, it was a rough transition. Teachers told NPR they've spent the past year experimenting with different methods of online and hybrid teaching, while also providing tech support for their students and families. Many say they routinely work 12-hour days and on weekends, yet struggle to form relationships with children virtually. Answering emails can take two hours a day. Rashon Briggs, who teaches high school special education in Los Angeles, spent a lot of time worrying about his students during remote learning (his district only recently started offering in-person options). "One of the biggest challenges is knowing that the kids were not getting the same level of service that they were getting in person," he says. Teachers in districts that opened earlier for in-person learning say they have additional responsibilities now, such as sanitizing desks between classes, making sure children follow school safety protocols and keeping track of students who have had to quarantine. "I have a calendar and it says who's quarantined, who is cleared to return on what day, who was absent," explains Rosamund Looney, who teaches first grade in Jefferson Parish, La. "Then I follow up with those families to see: 'Are you OK?' So there's just so much space taken up by that monitoring." Looney also worries about her students' learning. Everyone in her district has to wear masks in class, which she says she completely agrees with. But those masks mean she can't see her first graders' mouths as they learn phonics. "You are watching your teacher sound out words and then figuring out how to do that. And it's really hard for me to gauge what they are and aren't able to say." She says she's especially concerned about students who are more at risk of falling behind academically, like English learners. In New Hampshire, Crumrine says quarantines and positive cases among school staff have led to a constant shifting between fully online and hybrid classes. The fluctuations have been exhausting for her. "We started the year remote. Then we went back to school in October, then we were remote again in November, December. We went back to hybrid [in early February]," she says. New Hampshire's governor has now ordered all schools reopen for full-time, in-person classes by this week. "It feels like we're building the plane while we're flying it and the destination keeps changing on us," Crumrine says. Balancing work and home life In addition to worrying about their students, many teachers are also concerned about their own children. Crumrine, whose husband is also a teacher, has three children and says she feels pulled by competing demands. "I feel this sense of guilt that I'm not a good enough teacher for my students and I'm not a good mother for my own kids. It just feels like a constant wave of never feeling like I can do what I know I'm good at." Juelke, in North Dakota, is a single mom with a 9- and 3-year-old. "I'm juggling the children and making sure my daughter is in her class and my 3-year-old is entertained. And that is definitely taking a toll." Many teachers say they are eating and drinking more, and exercising and sleeping less. Briggs, in L.A., says his sleeping patterns are completely off. "Being awake all hours of the night, going to bed at 2, 3 a.m., drinking coffee late at night and try to finish work so I can be more prepared the next day." He's stressed, in part, because there are no clear work-life boundaries anymore. "When you're waking up in the same space that you're on Zoom, that you're grading papers, that you're watching Netflix, those lines are blurred very easily." Others say they're not as active at home, and they're eating more junk food and putting on weight. The tight schedules means they don't always move between classes, or even remember to drink water. "There are a lot of dehydrated teachers out there," says Looney. Many, like Juelke, say they miss having personal time. "That time where I could sit in the car and drive to work and just kind of relax a little, or my prep time at school alone. That's gone now. And so I feel like my mental health has struggled in that way." She says even though it breaks her heart, she's started looking for another profession. Leonda Archer, a middle school math teacher in Arlington, Va., says she's usually a very upbeat person, but the pandemic — coupled with the racial turmoil in the country — has taken a toll. She's African American, and says reports of Black men and women being killed by police makes her fear for her husband's safety. "There were some points of lowness that I hadn't experienced before. There are some days where I feel like it's hard to keep going." Archer says she has had difficulty sleeping, and doesn't have an appetite. "And right when I get into a groove, another traumatic experience happens." Briggs says it was hard not being able to process events like George Floyd's death and the Black Lives Matter protests with his colleagues. In the past, those conversations informed what he would say in the classroom to help his own students make sense of the news. "The teachers were not able to talk to each other about 'How do you talk about this? How do you present that?' " he says. "There was a lack of ability for us to communicate a message about social justice and rights and the wrongs." Crumrine says she misses the social aspect of being with her students, and other teachers. "We're not eating lunch together. We're not popping into each other's classrooms. We're all in our little silos." The school reopening divide Teachers told NPR they feel a growing chasm in their communities: Parents want schools to open, but teachers first want to make sure it's safe. Many feel they are not being included in these conversations, and their concerns aren't being taken seriously. Crumrine says it's been devastating hearing elected officials and parents criticize teachers, insisting that schools need to open, even though teachers are concerned about their own health. She says some community members acted like online classes meant teachers weren't working at all. In fact, she says, they were working harder than ever. "It just makes it feel so much worse when you read these horrible things that people say about us or these assumptions that they make about what we are or are not doing." She says many states, including her own, didn't prioritize vaccines for teachers, which to her revealed just "how deep that lack of value of educators is." Sarahi Monterrey, who teaches English learners in Waukesha, Wisc., says she's felt a "huge divide" in the community. "It almost seems like us against them." She was in a Zoom school board meeting where parents and students were present, and a teacher testified that her husband had COVID-19. "And a parent in the room said, 'Who cares?' And I was blown away. Just blown away." In Virginia, Archer says, at the beginning of the pandemic, "We were seen as angels. Like, 'Oh my God, I've been home with my child for two months, how do teachers do it?' And now the narrative has totally flip-flopped." She says she also misses "the vibe of school, the energy, all of that. But I don't want people to be sick." Archer works 12-hour days, and says people need to remember that teachers are people too. "Our profession is a nurturing one, but we also are humans that need to be poured into. We need to be nurtured, too." Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
break Global Commissions That Reflected on Ebola Outbreak Highlight Overlapping Conclusions in New PLOS Medicine Piece By Published On :: Thu, 19 May 2016 05:00:00 GMT To make the world safer against future infectious disease threats, national health systems should be strengthened, the World Health Organization’s emergency and outbreak response activities should be consolidated and bolstered, and research and development should be enhanced, says a new Policy Forum article that appears in the May 19 edition of PLOS Medicine. Full Article
break New Report Recommends Construction of Four New Polar Icebreakers of the Same Design as the Lowest-Cost Strategy for Protecting U.S. Interests in Arctic and Antarctic By Published On :: Tue, 11 Jul 2017 05:00:00 GMT The U.S. lacks icebreaking capability in the Arctic and Antarctic and should build four polar icebreakers with heavy icebreaking capability to help minimize the life-cycle costs of icebreaker acquisition and operations, says a new congressionally mandated letter report from the National Academies of Sciences, Engineering, and Medicine. Full Article
break Single Breakthrough Discovery for Citrus Greening Disease in Florida Unlikely, Says New Report By Published On :: Tue, 10 Apr 2018 05:00:00 GMT A single breakthrough discovery for managing citrus greening in Florida in the future is unlikely, says a new report by the National Academies of Sciences, Engineering, and Medicine. Full Article
break New Report Identifies Five Breakthroughs to Address Urgent Challenges and Advance Food and Agricultural Sciences by 2030 By Published On :: Wed, 18 Jul 2018 05:00:00 GMT A new report from the National Academies of Sciences, Engineering, and Medicine identifies the most promising scientific breakthroughs that are possible to achieve in the next decade to increase the U.S. food and agriculture system’s sustainability, competitiveness, and resilience. Full Article
break Breakthrough Solutions and Technologies Needed to Speed Cleanup of U.S. Nuclear Weapons Sites By Published On :: Mon, 04 Mar 2019 06:00:00 GMT A new report from the National Academies of Sciences, Engineering, and Medicine recommends changes in the way that the U.S. Department of Energy manages science and technology (S&T) development in order to accelerate the cleanup of radioactive waste and contaminated soil, groundwater, and facilities at U.S. nuclear weapons sites. Full Article
break NAS, NAE, and NAM Presidents Highlight Facts on Vaccine Safety in Light of Measles Outbreaks By Published On :: Fri, 08 Mar 2019 06:00:00 GMT The current measles outbreaks in the United States and elsewhere are being fueled by misinformation about the safety of vaccines. Full Article
break DOD Biological Threat Reduction Program Should Be Part of a New Interagency Mechanism to Coordinate Efforts to Prevent Biological Threats, Including Natural Disease Outbreaks - Report Offers Five-Year Strategy for BTRP By Published On :: Tue, 14 Apr 2020 04:00:00 GMT Over the next five years, the U.S. Department of Defense’s Biological Threat Reduction Program (BTRP) should encourage and be among co-leaders in the federal government’s development of an enduring interagency mechanism to address an array of biological threats – including natural disease outbreaks, accidental releases, and intentional attacks -- to deployed U.S. forces and to the nation itself, says a new report from the National Academies of Sciences, Engineering, and Medicine Full Article
break Protecting Human Health through Biotechnology Breakthroughs and Platforms By Published On :: Tue, 25 May 2021 04:00:00 GMT On November 15, 2020, after 4 months in large-scale Phase 3 clinical testing, Moderna received resounding proof that its new class of medicines based on messenger RNA encased in lipid nanoparticles could be safely deployed as a highly effective vaccine to combat the COVID-19 pandemic. Full Article
break Breaking Down Barriers to Entrepreneurship for Women By Published On :: Wed, 21 Jul 2021 04:00:00 GMT Although the number of women among new inventors is edging upward, women still make up only about 13 percent of inventors in the economy overall. What keeps more women from engaging in invention and entrepreneurship? A recent workshop explored that question and how to remove the obstacles. Full Article
break Breakthrough Prize Foundation Partners with U.S. National Academy of Sciences to Support Scientists Forced to Flee Ukraine By Published On :: Tue, 29 Mar 2022 04:00:00 GMT With a $1 million donation, the Breakthrough Prize Foundation joins a growing number of individuals and institutions that are supporting an NAS effort to help displaced Ukrainian researchers relocate, continue their work, and stay connected to the international scientific community. Full Article
break Scientific Organizations Form International Group to Advance Ukrainian Science and Support Researchers - Breakthrough Prize Foundation Provides $3 Million By Published On :: Mon, 24 Oct 2022 04:00:00 GMT With a $3 million donation from the Breakthrough Prize Foundation, a high-level, international coordinating group of scientific organizations has been established to take concrete steps to support Ukraine’s scientists and research community with the aim of rebuilding a successful global science and innovation system in Ukraine. Full Article
break Google’s ad tech in peril as EU joins US’s breakup bandwagon By cio.economictimes.indiatimes.com Published On :: Fri, 23 Jun 2023 09:42:21 +0530 The European Commission last week joined the Department of Justice in touting a breakup as a viable remedy for the California-based tech giant’s alleged monopoly abuses. A selloff order would strike at the heart of one of Google’s biggest money spinners, although it could still be years away due to the legal processes being played out. Full Article
break Dunkin' Donuts breakfast sandwich By www.snackandbakery.com Published On :: Mon, 29 Aug 2016 15:00:00 -0400 Dunkin' Donuts recently introduced a new breakfast sandwich. Full Article
break Geefree gluten-free sausage, egg, and cheese breakfast pocket By www.snackandbakery.com Published On :: Thu, 06 Apr 2017 09:00:00 -0400 Geefree's gluten-free puff pastry wraps around a combination of sausage, scrambled eggs, and cheddar cheese - all of the flavor, and none of the gluten. Full Article
break Johnsonville Premium Breakfast Sandwich collection By www.snackandbakery.com Published On :: Wed, 25 Oct 2017 09:00:00 -0400 Johnsonville has introduced its Premium Breakfast Sandwich Collection, which features five new signature hand-held breakfast options. Full Article