balance

The week that was: A balance of economy and public health

As heads of state, local leaders, business owners and individual citizens weighed the costs of re-opening the global economy, fears of new outbreaks grew. A central question emerged: How much infection and loss of life will emerge amid the push to restart business?




balance

Challenge to find right balance in draft budget

One of my passions as a councillor and a key commitment to my community was to simplify local government processes and clarify what as unnecessarily complex. Break the obfuscation nexus, you may say.




balance

Striving for balance: maintaining marten habitat while reducing fuels

Martens are small forest carnivores associated with dense, mature forests.




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Finding a Balance: College, Work, Family ... and Issues from TBI

Returning to school as a veteran — especially with a brain injury — can be difficult. Adam suggests strategies like starting slowly or taking a smaller course load that balances better with work and life.




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Harmony > Balance with Jason Calacanis

Today we’re going back to San Francisco with myself and Jason Calacanis on stage during my tour stop for my book Creative Calling. Jason is an investor and long time host of the This Week in Startups podcast. And, of course, Jason wastes no time in our conversation. He goes right to the heart of the matter by getting into failure, venture capitol, knowing when to quit, and when to push through. Enjoy! FOLLOW JASON: facebook | twitter | website Listen to the Podcast Subscribe   This podcast is brought to you by CreativeLive. CreativeLive is the world’s largest hub for online creative education in photo/video, art/design, music/audio, craft/maker, money/life and the ability to make a living in any of those disciplines. They are high quality, highly curated classes taught by the world’s top experts — Pulitzer, Oscar, Grammy Award winners, New York Times best selling authors and the best entrepreneurs of our times.

The post Harmony > Balance with Jason Calacanis appeared first on Chase Jarvis Photography.




balance

Extremal values of the Sackin balance index for rooted binary trees. (arXiv:1801.10418v5 [q-bio.PE] UPDATED)

Tree balance plays an important role in different research areas like theoretical computer science and mathematical phylogenetics. For example, it has long been known that under the Yule model, a pure birth process, imbalanced trees are more likely than balanced ones. Therefore, different methods to measure the balance of trees were introduced. The Sackin index is one of the most frequently used measures for this purpose. In many contexts, statements about the minimal and maximal values of this index have been discussed, but formal proofs have never been provided. Moreover, while the number of trees with maximal Sackin index as well as the number of trees with minimal Sackin index when the number of leaves is a power of 2 are relatively easy to understand, the number of trees with minimal Sackin index for all other numbers of leaves was completely unknown. In this manuscript, we fully characterize trees with minimal and maximal Sackin index and also provide formulas to explicitly calculate the number of such trees.




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Two-Stream FCNs to Balance Content and Style for Style Transfer. (arXiv:1911.08079v2 [cs.CV] UPDATED)

Style transfer is to render given image contents in given styles, and it has an important role in both computer vision fundamental research and industrial applications. Following the success of deep learning based approaches, this problem has been re-launched recently, but still remains a difficult task because of trade-off between preserving contents and faithful rendering of styles. Indeed, how well-balanced content and style are is crucial in evaluating the quality of stylized images. In this paper, we propose an end-to-end two-stream Fully Convolutional Networks (FCNs) aiming at balancing the contributions of the content and the style in rendered images. Our proposed network consists of the encoder and decoder parts. The encoder part utilizes a FCN for content and a FCN for style where the two FCNs have feature injections and are independently trained to preserve the semantic content and to learn the faithful style representation in each. The semantic content feature and the style representation feature are then concatenated adaptively and fed into the decoder to generate style-transferred (stylized) images. In order to train our proposed network, we employ a loss network, the pre-trained VGG-16, to compute content loss and style loss, both of which are efficiently used for the feature injection as well as the feature concatenation. Our intensive experiments show that our proposed model generates more balanced stylized images in content and style than state-of-the-art methods. Moreover, our proposed network achieves efficiency in speed.




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Load balancing on hetrogenous processing cluster based on exceeded load imbalance factor threshold determined by total completion time of multiple processing phases

Methods and systems for managing data loads on a cluster of processors that implement an iterative procedure through parallel processing of data for the procedure are disclosed. One method includes monitoring, for at least one iteration of the procedure, completion times of a plurality of different processing phases that are undergone by each of the processors in a given iteration. The method further includes determining whether a load imbalance factor threshold is exceeded in the given iteration based on the completion times for the given iteration. In addition, the data is repartitioned by reassigning the data to the processors based on predicted dependencies between assigned data units of the data and completion times of a plurality of the processers for at least two of the phases. Further, the parallel processing is implemented on the cluster of processors in accordance with the reassignment.




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Flux balance analysis with molecular crowding

Methods are provided herein for: calculating cell growth rates in various environments and genetic backgrounds; calculating the order of substrate utilization from a defined growth medium; calculating metabolic flux reorganization in various environments and at various growth rates; and calculating the maximum metabolic rate and optimal metabolite concentrations and enzyme activities by applying a computational optimization method to a kinetic model of a metabolic pathway. The optimization methods use intracellular molecular crowding parameters and/or well as kinetic rates to assist in modeling metabolic activity.




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Balanced snap ring

A balanced snap ring and method of making a balanced snap ring is disclosed. The snap ring has a circular shape wherein the circular shape has a circumference. The snap ring has a body section and a protrusion extending axially from the body section. The protrusion is formed partially around the circumference. Additionally, a transmission with a balanced snap ring is disclosed.




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Camera module for tilt balance of lens

The present invention relates to a camera module including: a lens unit mounted with at least one or more lenses; an image sensor mounted with an image pickup device for converting a light converged through the lenses to an electric signal; a PCB (Printed Circuit Board) mounted with the image sensor; and a holder accommodated inside the lens unit for supporting the lens unit, wherein the lens unit is bonded and fixed at an inner surface of the holder, whereby the lens unit mounted with a plurality of lenses is bonded to a lateral surface of a holder to prevent generation of vertical tilting phenomenon at the lens unit caused by a conventional improper coating of epoxy, and particularly, the coating of epoxy on the lateral surface of the holder advantageously enhances adhesive power to increase a bonded area.




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Load balancer

According to one embodiment, an apparatus comprises an interface and one or more processors. The interface receives a request for a web page from a web browser. The one or more processors select a subset of web servers from a resource pool according to a load balancing determination. The one or more processors send the request to at least two of the web servers of the subset before receiving any response from the other web servers. Upon receiving one or more responses from distinct web servers, the one or more processors selects a response to communicate to the web browser.




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Apparatus and method of compensating for I/Q imbalance in direct up-conversion system

An apparatus and a method of compensating for an I/Q imbalance in a direct up-conversion system prevents the performance of the system from being deteriorated by efficiently compensating for an I/Q timing skew, an I/Q phase imbalance, and an I/Q gain imbalance by using a characteristic of an OFDM scheme in an Orthogonal Frequency Domain Multiple (Access) (OFDM(A)) system using a direct up-conversion scheme. According to the apparatus and the method of compensating for an I/Q imbalance in the direct up-conversion system of the present invention, an OFDM(A) system using a direct up-conversion scheme may efficiently compensate for I/Q timing skew, I/Q phase imbalance, and I/Q gain imbalance by using a characteristic of an OFDMA scheme, so that a performance of the system is prevented from being deteriorated.




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Method and device for retransmitting data under antenna gain imbalance

The disclosure provides a method and device for retransmitting data under antenna gain imbalance, and the method includes: determining that gains of multiple antennas at a transmission terminal are imbalanced; using a better spatial sub-channel in the multiple antennas to retransmit data when streams transmitted by the multiple antennas adopt a same Modulation and Coding Scheme; and using a better spatial sub-channel in the multiple antennas to retransmit data and/or using a single-stream approach to retransmit data when the streams transmitted by the multiple antennas adopt different Modulation and Coding Schemes. The disclosure selects a corresponding retransmission approach according to the condition of a spatial sub-channel on which streams have an error, thus improving and ensuring success rate for retransmitting a stream.




balance

Unbalanced-balanced conversion circuit element

An unbalanced-balanced conversion circuit element includes an inductor connected in series between an unbalanced terminal and a first balanced terminal. The first balanced terminal side of the inductor is grounded via a capacitor. A capacitor is connected in series between the unbalanced terminal and a second balanced terminal. An inductor is connected between the first balanced terminal side of the inductor and the second balanced terminal side of the capacitor. In a laminate defining the unbalanced-balanced conversion circuit element, the capacitor is spaced far from a mounting surface of the laminate in comparison with other circuit elements.




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Crimp-imbalanced fabrics

Crimp-imbalanced fabric systems are accomplished by varying the levels of yarn crimp within a single fabric layer and across layers of a multi-layer fabric system. The method includes developing a crimp in the yarn (utilized for producing a fabric layer) by optionally pulling the yarn through a solution that substantially coats the yarn. The optionally removable coating has a thickness that ensures a proper amount of crimp in the yarn. The tension in the yarn is controlled; the yarn is weaved; and a crimp is applied in the yarn. Once the crimp is applied, families of the crimped yarn are utilized as a single layer or multiple layer system to increase performance attributes including enhanced energy absorption.




balance

Current balance control in converter for doubly fed induction generator wind turbine system

Systems and methods for reducing current imbalance between parallel bridge circuits used in a power converter of a doubly fed induction generator (DFIG) system are provided. A control system can monitor the bridge current of each of the bridge circuits coupled in parallel and generate a feedback signal indicative of the difference in bridge current between the parallel bridge circuits. Command signals for controlling the bridge circuits can then be developed based on the feedback signal to reduce current imbalance between the bridge circuits. For instance, the pulse width modulation of switching devices (e.g. IGBTs) used in the bridge circuits can be modified to reduce current imbalance between the parallel bridge circuits.




balance

Counterbalance mechanism for bottom-hinged aircraft fuselage doors

A counterbalance mechanism for counterbalancing weight of a bottom-hinged door (such as a clamshell-type airstair door of an aircraft) includes an operator handle, a hoist rod pivotally connected at one end to the operator handle and at an opposite end thereof to the door near a bottom region thereof. A force accumulator assembly is provided which includes a force biasing member which accumulates and dissipates a bias force when opening and closing the door, respectively, to provide mechanical counterbalance to the weight of the door. A bellcrank assembly operatively connects the operator handle to the force accumulator. In such a manner, weight counterbalancing of the door is achieved.




balance

Control of balance drift in turbocharger rotating assembly

A turbocharger for an internal combustion engine includes a bearing housing with a bearing bore and a thrust wall. The bearing housing includes a journal bearing disposed within the bore. The turbocharger also includes a shaft supported by the journal bearing for rotation about an axis within the bore. The turbocharger also includes a turbine wheel fixed to the shaft and configured to be rotated about the axis by the engine's post-combustion gasses. The turbocharger additionally includes a compressor wheel fixed to the shaft and configured to pressurize an ambient airflow. Furthermore, the turbocharger includes a thrust bearing assembly pressed onto the shaft and configured to transmit thrust forces developed by the turbine wheel to the thrust wall. Pressing the thrust bearing assembly onto the shaft minimizes radial motion between the thrust bearing assembly and the shaft. An internal combustion engine employing such a turbocharger is also disclosed.




balance

BALANCE EXERCISE DEVICE

A multi-purpose balance exercise device designed to be used in multiple positions and for diverse exercises. For example, various embodiments allow for the multipurpose device to be use as an aerobic step device as well as the ability to easily adjust the device to various heights to easily decrease the level of difficulty of the device for use during various exercises. The balance exercise device can provide a polarity of handles and grab points both horizontally and vertically, which allow for an enhanced number of exercises or movements using either the top and/or bottom of the device. The balance exercise device includes a flexible bladder filled with air, other gases, or gels attached to a substantially rigid base. The base can include an interior within which features such as handles are disposed to provide a gripping or lifting exercise to which the balance exercise device can be used.




balance

Method and apparatus for redistributing an imbalance in a laundry treating appliance

An apparatus and method for detecting an imbalance in the laundry load and effecting a redistribution of the imbalance by reducing the rotational speed of the treating chamber such that part of the load may redistribute while part of the load remains satellized, without ceasing rotation, and increasing the rotational speed back to a spin speed after redistribution.




balance

Production of low sodium salt with balanced mineral content

A process is provided for preparing a salt product with reduced sodium content including the step of providing a concentrated brine, which is typically seawater, to which has been added potassium chloride. The mixture is transferred to a crystallizer unit where at least a portion of the mix is transferred to the crystallizer through a washing column. Liquid is evaporated from the crystallizer such that crystals form, crystals are passed from the crystallizer through said washing column to a separating unit such that in the passing through the washing column the crystals are rinsed with the brine portion being transferred as a counter current through the column. The inventive process is characterized by recycling of the brine from which the salt crystallizes, thus all main ingredients of the mixed input brine reach a steady equilibrium concentration in the mother liquor in the crystallizer. These will then precipitate as crystals, as more of the respective substances gets added to the mother liquor through inflow of mixed input brine. None of the liquor is purged out of the system as in conventional salt crystallizers. All the components in the feed are substantially contained in the product from the crystallizer either as crystalline material or soluble ingredients.




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Electrically and Magnetically Enhanced Ionized Physical Vapor Deposition Unbalanced Sputtering Source

An electrically and magnetically enhanced ionized physical vapor deposition (I-PVD) magnetron apparatus and method is provided for sputtering material from a cathode target on a substrate, and in particular, for sputtering ceramic and diamond-like coatings. The electrically and magnetically enhanced magnetron sputtering source has unbalanced magnetic fields that couple the cathode target and additional electrode together. The additional electrode is electrically isolated from ground and connected to a power supply that can generate positive, negative, or bipolar high frequency voltages, and is preferably a radio frequency (RF) power supply. RF discharge near the additional electrode increases plasma density and a degree of ionization of sputtered material atoms.




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How professional careers, family, farming and netball find balance among the women gracing my team

Think rural women are all farmers' wives? You need to meet my netball team.




balance

'I was always hurting myself': This children's book author is striving to turn the gender imbalance on its head

In her time as a professional skier, a research student and working at Google, Annabel Blake noticed a reoccurring theme: an alarming shortage of women, and she's on a mission to change that for the next generation.




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Athlete scores a balance between work, life and diabetes

Not much gets in the way of Tami Willey achieving her goals: after all she is a professional basketball player. What fans don't always see is what Tami's life is like off the court, juggling a career, a family and type 1 diabetes.




balance

Letters: Striking a balance (4/29/20)

Striking a balance Easing the restrictions on COVID-19 risky activities is like setting a speed limit on our roads. The higher the speed limit, the greater the freedom to drive as one pleases, and the greater the number of statistically probable deaths. There are those who would advocate for unfettered freedom notwithstanding higher death rates, and vice versa. The political and economic challenge is in finding a socially acceptable balance. Although one might differ from our elected leaders on where to set the limits, or how fast to proceed in adjusting those limits, there is going to be a trial-and-error period during which data and societal feedback will trend toward an acceptable trade-off between freedom and harm. Let’s cut our local leaders some slack as they attempt to strike a balance.




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Tamia Reveals the Secret to Her Career-Family Balance



“We live a very as-normal-as-possible life,” she said.




balance

New Theme: Rebalance

Introducing Rebalance, a free theme for photographers, artists, and graphic designers.




balance

My Three Tips for Work, Life, School, and CPA Balance

Have you ever heard of that phrase, “work-life balance?” Well try “work, life, school, CPA balance” for a little extra challenge! The thought of achieving those three little letters every accountant dreams of- “CPA“- can be quite daunting, especially if you are trying to study while you are in school. But, I am here to … Continue reading "My Three Tips for Work, Life, School, and CPA Balance"





balance

Losing jobs, saving jobs: As unemployment soars, the nation and individual states try to balance health and economic concerns

The patient, laid up in the ICU, gets sicker. Thursday, 3.2 million more people joined the ranks of the unemployed, bringing to 33.5 million the number of Americans who’ve lost jobs since mid-March. Believe it: One in five of those employed before this living, dying hell began is now seeking jobless benefits.




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Elliott: USA Hockey's Lamoureux twins balance elite competition with motherhood

Twins Monique and Jocelyne Lamoureux are among the first players to take advantage of the maternity and child-care provisions in their new labor agreement with USA Hockey.




balance

Feds tweak driverless-car guidelines, seek to balance safety and tech development

Transportation Secretary Elaine Chao says safety is the top priority for robot cars – but so is intellectual property.




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velocityconf: Free webcast from our friends at @citrix 5/29 http://t.co/IOeY4U0wUP Learn to consolidate 40 load balancers and ADCs into single platform

velocityconf: Free webcast from our friends at @citrix 5/29 http://t.co/IOeY4U0wUP Learn to consolidate 40 load balancers and ADCs into single platform




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Brain manganese and the balance between essential roles and neurotoxicity [Molecular Bases of Disease]

Manganese (Mn) is an essential micronutrient required for the normal development of many organs, including the brain. Although its roles as a cofactor in several enzymes and in maintaining optimal physiology are well-known, the overall biological functions of Mn are rather poorly understood. Alterations in body Mn status are associated with altered neuronal physiology and cognition in humans, and either overexposure or (more rarely) insufficiency can cause neurological dysfunction. The resultant balancing act can be viewed as a hormetic U-shaped relationship for biological Mn status and optimal brain health, with changes in the brain leading to physiological effects throughout the body and vice versa. This review discusses Mn homeostasis, biomarkers, molecular mechanisms of cellular transport, and neuropathological changes associated with disruptions of Mn homeostasis, especially in its excess, and identifies gaps in our understanding of the molecular and biochemical mechanisms underlying Mn homeostasis and neurotoxicity.




balance

Can the UK Strike a Balance Between Openness and Control?

2 March 2020

Hans Kundnani

Senior Research Fellow, Europe Programme
Rather than fetishizing free trade, Britain should aim to be a model for a wider recalibration of sustainable globalization.

2020-03-02-Johnson.jpg

Boris Johnson speaks at the Old Naval College in Greenwich on 3 February. Photo: Getty Images.

This week the UK will start negotiating its future relationship with the European Union. The government is trying to convince the EU that it is serious about its red lines and is prepared to walk away from negotiations if the UK’s ‘regulatory freedom’ is not accepted – a no-deal scenario that would result in tariffs between the EU and the UK. Yet at the same time the story it is telling the world is that Britain is ‘re-emerging after decades of hibernation as a campaigner for global free trade’, as Boris Johnson put it in his speech in Greenwich a few weeks ago.

The EU is understandably confused. It’s a bit odd to claim to be campaigning for free trade at the exact moment you are creating new barriers to trade. If Britain were so committed to frictionless trade, it wouldn’t have left the EU in the first place – and having decided to leave, it would have sought to maintain a close economic relationship with the EU, like that of Norway, rather than seek a basic trade deal like Canada’s. 

As well as creating confusion, the narrative also absurdly idealizes free trade. Johnson invoked Richard Cobden and the idea that free trade is ‘God’s diplomacy – the only certain way of uniting people in the bonds of peace since the more freely goods cross borders the less likely it is that troops will ever cross borders’. But the idea that free trade prevents war was shattered by the outbreak of the First World War, which brought to an end the first era of globalization.

We also know that the domestic effects of free trade are more complex and problematic than Johnson suggested. Economic liberalization increases efficiency by removing friction but also creates disruption and has huge distributional consequences – that is, it creates winners and losers. In a democracy, these consequences need to be mitigated.

In any case, the world today is not the same as the one in which Cobden lived. Tariffs are at a historically low level – and many non-tariff barriers have also been removed. In other words, most of the possible gains from trade liberalization have already been realized. Johnson talked about the dangers of a new wave of protectionism. But as the economist Dani Rodrik has argued, the big problem in the global economy is no longer a lack of openness, it is a lack of democratic legitimacy.

The UK should therefore abandon this confusing and misleading narrative and own the way it is actually creating new barriers to trade – and do a better job of explaining the legitimate reasons for doing so. Instead of simplistically talking up free trade, we should be talking about the need to balance openness and economic efficiency with democracy and a sense of control, which is ultimately what Brexit was all about. Instead of claiming to be a ‘catalyst for free trade’, as Johnson put it, the UK should be talking about how it is trying to recalibrate globalization and, in doing so, make it sustainable.

In the three decades after the end of the Cold War, globalization got out of control as barriers to the movement of capital and goods were progressively removed – what Rodrik called ‘hyper-globalization’ to distinguish it from the earlier, more moderate phase of globalization. This kind of deep integration necessitated the development of a system of rules, which have constrained the ability of states to pursue the kind of economic policy, particularly industrial policy, they want, and therefore undermined democracy.

Hyper-globalization created a sense that ‘the nation state has fundamentally lost control of its destiny, surrendering to anonymous global forces’, as the economist Barry Eichengreen put it. Throughout the West, countries are all struggling with the same dilemma – how to reconcile openness and deep integration on the one hand, and democracy, sovereignty and a sense of control on the other.

Within the EU, however, economic integration and the abolition of barriers to the movement of capital and goods went further than in the rest of the world – and the evolution of the principle of freedom of movement after the Maastricht Treaty meant that barriers to the internal movement of people were also eliminated as the EU was enlarged. What happened within the EU might be thought of as ‘hyper-regionalization’ – an extreme example, in a regional context, of a global trend.

EU member states have lost control to an even greater extent than other nation states – albeit to anonymous regional rather than global forces – and this loss of control was felt intensely within the EU. It is therefore logical that this led to an increase in Euroscepticism. Whereas the left wants to restore some barriers to the movement of capital and goods, the right wants to restore barriers to the movement of people.

However, having left the EU, the UK is uniquely well placed to find a new equilibrium. The UK has an ideological commitment to free trade that goes back to the movement to abolish the Corn Laws in the 1840s – which Johnson’s speech expressed. It is difficult to imagine the UK becoming protectionist in any meaningful sense. But at the same time, it has a well-developed sense of national and popular sovereignty, and the sense that the two go together – which is why it was so sensitive to the erosion of them through the EU. This means that Britain is unlikely to go to one extreme or the other.

In other words, the UK may be the ideal country to find a new balance between openness and integration on the one hand, and a sense of control on the other. If it can find this balance – if it can make Brexit work – the UK could be a model for a wider recalibration of sustainable globalization. That, rather than fetishizing free trade, is the real contribution the UK can make.

A version of this article was originally published in the Observer.




balance

Brain manganese and the balance between essential roles and neurotoxicity [Molecular Bases of Disease]

Manganese (Mn) is an essential micronutrient required for the normal development of many organs, including the brain. Although its roles as a cofactor in several enzymes and in maintaining optimal physiology are well-known, the overall biological functions of Mn are rather poorly understood. Alterations in body Mn status are associated with altered neuronal physiology and cognition in humans, and either overexposure or (more rarely) insufficiency can cause neurological dysfunction. The resultant balancing act can be viewed as a hormetic U-shaped relationship for biological Mn status and optimal brain health, with changes in the brain leading to physiological effects throughout the body and vice versa. This review discusses Mn homeostasis, biomarkers, molecular mechanisms of cellular transport, and neuropathological changes associated with disruptions of Mn homeostasis, especially in its excess, and identifies gaps in our understanding of the molecular and biochemical mechanisms underlying Mn homeostasis and neurotoxicity.




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Unconstrained Presidency? Checks and Balances in the Trump Era




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Maintaining a Balance Part 2

Researcher: Daniel Rothman, MIT. Dan Rothman talks about how math helped understand a mass extinction.




balance

CBD News: Integral to the balance of nature, wildlife nurtures us with a sense of wonder and serves as a source of inspiration.




balance

Can the UK Strike a Balance Between Openness and Control?

2 March 2020

Hans Kundnani

Senior Research Fellow, Europe Programme
Rather than fetishizing free trade, Britain should aim to be a model for a wider recalibration of sustainable globalization.

2020-03-02-Johnson.jpg

Boris Johnson speaks at the Old Naval College in Greenwich on 3 February. Photo: Getty Images.

This week the UK will start negotiating its future relationship with the European Union. The government is trying to convince the EU that it is serious about its red lines and is prepared to walk away from negotiations if the UK’s ‘regulatory freedom’ is not accepted – a no-deal scenario that would result in tariffs between the EU and the UK. Yet at the same time the story it is telling the world is that Britain is ‘re-emerging after decades of hibernation as a campaigner for global free trade’, as Boris Johnson put it in his speech in Greenwich a few weeks ago.

The EU is understandably confused. It’s a bit odd to claim to be campaigning for free trade at the exact moment you are creating new barriers to trade. If Britain were so committed to frictionless trade, it wouldn’t have left the EU in the first place – and having decided to leave, it would have sought to maintain a close economic relationship with the EU, like that of Norway, rather than seek a basic trade deal like Canada’s. 

As well as creating confusion, the narrative also absurdly idealizes free trade. Johnson invoked Richard Cobden and the idea that free trade is ‘God’s diplomacy – the only certain way of uniting people in the bonds of peace since the more freely goods cross borders the less likely it is that troops will ever cross borders’. But the idea that free trade prevents war was shattered by the outbreak of the First World War, which brought to an end the first era of globalization.

We also know that the domestic effects of free trade are more complex and problematic than Johnson suggested. Economic liberalization increases efficiency by removing friction but also creates disruption and has huge distributional consequences – that is, it creates winners and losers. In a democracy, these consequences need to be mitigated.

In any case, the world today is not the same as the one in which Cobden lived. Tariffs are at a historically low level – and many non-tariff barriers have also been removed. In other words, most of the possible gains from trade liberalization have already been realized. Johnson talked about the dangers of a new wave of protectionism. But as the economist Dani Rodrik has argued, the big problem in the global economy is no longer a lack of openness, it is a lack of democratic legitimacy.

The UK should therefore abandon this confusing and misleading narrative and own the way it is actually creating new barriers to trade – and do a better job of explaining the legitimate reasons for doing so. Instead of simplistically talking up free trade, we should be talking about the need to balance openness and economic efficiency with democracy and a sense of control, which is ultimately what Brexit was all about. Instead of claiming to be a ‘catalyst for free trade’, as Johnson put it, the UK should be talking about how it is trying to recalibrate globalization and, in doing so, make it sustainable.

In the three decades after the end of the Cold War, globalization got out of control as barriers to the movement of capital and goods were progressively removed – what Rodrik called ‘hyper-globalization’ to distinguish it from the earlier, more moderate phase of globalization. This kind of deep integration necessitated the development of a system of rules, which have constrained the ability of states to pursue the kind of economic policy, particularly industrial policy, they want, and therefore undermined democracy.

Hyper-globalization created a sense that ‘the nation state has fundamentally lost control of its destiny, surrendering to anonymous global forces’, as the economist Barry Eichengreen put it. Throughout the West, countries are all struggling with the same dilemma – how to reconcile openness and deep integration on the one hand, and democracy, sovereignty and a sense of control on the other.

Within the EU, however, economic integration and the abolition of barriers to the movement of capital and goods went further than in the rest of the world – and the evolution of the principle of freedom of movement after the Maastricht Treaty meant that barriers to the internal movement of people were also eliminated as the EU was enlarged. What happened within the EU might be thought of as ‘hyper-regionalization’ – an extreme example, in a regional context, of a global trend.

EU member states have lost control to an even greater extent than other nation states – albeit to anonymous regional rather than global forces – and this loss of control was felt intensely within the EU. It is therefore logical that this led to an increase in Euroscepticism. Whereas the left wants to restore some barriers to the movement of capital and goods, the right wants to restore barriers to the movement of people.

However, having left the EU, the UK is uniquely well placed to find a new equilibrium. The UK has an ideological commitment to free trade that goes back to the movement to abolish the Corn Laws in the 1840s – which Johnson’s speech expressed. It is difficult to imagine the UK becoming protectionist in any meaningful sense. But at the same time, it has a well-developed sense of national and popular sovereignty, and the sense that the two go together – which is why it was so sensitive to the erosion of them through the EU. This means that Britain is unlikely to go to one extreme or the other.

In other words, the UK may be the ideal country to find a new balance between openness and integration on the one hand, and a sense of control on the other. If it can find this balance – if it can make Brexit work – the UK could be a model for a wider recalibration of sustainable globalization. That, rather than fetishizing free trade, is the real contribution the UK can make.

A version of this article was originally published in the Observer.




balance

Lipid sensing tips the balance for a key cholesterol synthesis enzyme [Images in Lipid Research]




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Amylin/Calcitonin Receptor-Mediated Signaling in POMC Neurons Influences Energy Balance and Locomotor Activity in Chow-Fed Male Mice

Amylin, a pancreatic hormone and neuropeptide, acts principally in the hindbrain to decrease food intake and has been recently shown to act as a neurotrophic factor to control the development of AP->NTS and ARC->PVN axonal fiber outgrowth. Amylin is also able to activate ERK signaling specifically in POMC neurons independently of leptin. To investigate the physiological role of amylin signaling in POMC neurons, the core component of the amylin receptor, calcitonin receptor (CTR) was depleted from POMC neurons using an inducible mouse model. The loss of CTR in POMC neurons leads to increased body weight gain, increased adiposity, and glucose intolerance in male knockout mice, characterized by decreased energy expenditure (EE) and decreased expression of uncoupling protein 1 (UCP1) in brown adipose tissue (BAT). Furthermore, a decreased spontaneous locomotor activity and absent thermogenic reaction to the application of the amylin receptor agonist were observed in male and female mice. Together, these results show a significant physiological impact of amylin/calcitonin signaling in CTR-POMC neurons on energy metabolism and demonstrate the need for sex-specific approaches in obesity research and potentially treatment.




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Has the balance of screening for AAA tipped towards harm?

Abdominal aortic aneurysms (AAA) are usually asymptomatic until they rupture, which is fatal in more than 80% of cases. Screening aims to detect the aneurysm before it ruptures, enabling preventive surgery and hence reducing morbidity and mortality. However, preventive surgery has a mortality of 3.9-4.5%. As the prevalence of risk factors, ie...




balance

Britain Must Balance a Transatlantic Heart With a European Head

19 December 2019

Robin Niblett

Director and Chief Executive, Chatham House
Returning from an EU-rooted foreign and economic policy to one which is more international in outlook will be difficult, take time, and be more costly than the new UK government currently envisages.

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Boris Johnson chairs the first cabinet meeting after winning a majority of 80 seats in the 2019 UK general election. Photo by Matt Dunham – WPA Pool/Getty Images.

The convincing general election win for the Conservative Party and Boris Johnson opens a new chapter in British history. On 31 January 2020, Britain will withdraw from the EU and return to its historical position as a separate European power.

Recognising the strategic significance of this change, the Queen’s speech opening the new parliament stated that 'the government will undertake the deepest review of Britain's security, defence, and foreign policy since the end of the Cold War'. But in what context?

Prime Minister Boris Johnson and other Brexit supporters have yearned for Britain to return to its exceptional trajectory. In their view, Britain can once again become a trading nation - more global in outlook and ambition than its European neighbours, freed from the shackles of an ageing and fractured European continent and its deadening regulatory hand.

This imagery makes good copy. But the 21st century does not offer Britain the same opportunities as did the 18th, 19th or early 20th centuries. This is a different world, and Britain’s position in it needs to be crafted with a sharp eye to what is possible.

Geopolitics undergoing wrenching change

This is not declinism. The UK remains an economically strong and politically influential country by relative global standards – it is currently the fifth or sixth largest economy in the world, and the second largest donor of official development assistance. It has ubiquitous cultural brands from fashion and music to the royal family, and an eminent diplomatic and security position at the heart of all of the world’s major international institutions and alliances, from NATO and the UN security council to the IMF, G7, G20 and Commonwealth. 

But Britain leaves the EU just as the geopolitical landscape is undergoing wrenching change. The United States has turned inwards, closer to its own historic norm, and is undermining the international institutions which it created alongside Britain in the 1940s. China’s international influence is on the rise alongside its vast and still growing economy, challenging traditional norms of individual freedom and public transparency.

Russia is navigating the cracks and crevices of the fracturing rules-based international order with ruthless efficiency. Sensing the change in the wind, many governments are now back-tracking on their post-Cold War transitions to more open and democratic societies.

The implications of this new context have yet to be fully internalised by those who look forward to Britain’s future outside the EU. Britain will be negotiating new trade deals in an increasingly transactional, fragmented and protectionist international economic environment. It will be trying to sell its world-class services into markets where national control over finance, law, technology and media is increasingly prized.

Making new diplomatic inroads will be no easier. The government will face strong internal and external criticism if it lends security assistance to states that are simultaneously clamping down on their citizens’ rights. With the number of military personnel in decline and investment in new equipment stretched across multiple expensive platforms, the UK could struggle to project meaningful defence cooperation to new security partners in Asia at the same time as upholding its NATO commitments and its deployments in conflict zones around the world.

Britain also opens its new global chapter at a time when it is changing domestically. There is no over-riding reason for a missionary British foreign policy – neither the economic returns or image of national glory that drove Empire, nor the existential defence of its land, interests and freedom that drove it during the Cold War.

Stretching liberal interventionism to Iraq, as Tony Blair did when he was prime minister, and to Libya as David Cameron did in 2011, has injected a deep dose of popular scepticism to the idea that Britain - with or without allies - can or should help make the world in its own image.

This more defensive mindset – epitomised by parliament’s refusal to use military force to punish President Bashar al Assad’s regime for using chemical weapons against its citizens in 2013 – will not abate soon. Especially when the new government’s political bandwidth will be stretched by fiendishly complex trade-offs between its financial promises to support domestic renewal, the imperatives of striking and implementing a new free trade agreement with the EU, and the economic consequences of leaving the single market.

All this points to the fact that the most important step for Britain at the beginning of this new national chapter will be to establish an effective partnership with the EU and its member states. They face the same international risks as Britain and have as much to gain from the preservation of rules-based international behaviour. Recognising the continued interdependence between Britain and the EU will offer both sides greater leverage in a more competitive and hostile world.

A new transatlantic relationship

Once it has agreed its new relationship with the EU, Britain can turn to crafting its new relationship with the mighty United States. US-UK economic interdependence and close security ties should help discipline the bilateral economic relationship. The more difficult challenge will be for the UK to avoid falling into fissures between the US and the EU over how to manage bilateral relations with China and Russia, particularly if President Trump wins a second term.

Britain will have to get used to this difficult balancing act between its transatlantic heart and European head after Brexit. This makes it all the more important for the UK to develop new diplomatic and commercial initiatives with countries that are also struggling to cope with the current uncertain, transactional international environment.

Canada, Japan, South Korea, Australia and New Zealand can grow as bilateral economic partners and as allies in international institutions, such as the G7, OECD and WTO. They may even open a door to British engagement in regional trade arrangements such as the Comprehensive and Progressive Agreement for Trans-Pacific Partnership (CP-TPP), which do not require the same political commitments as EU membership.

Turning from an EU-rooted foreign and economic policy to one that is once again more international in outlook will be difficult, take time and be more costly than the government currently envisages. The irony is that for this to be successful requires sustained political investment by the Johnson government to build a strong relationship with the EU that it is focused on leaving.




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