Cosappzsearch.online redirect removal instructions

What is cosappzsearch.online?

Cosappzsearch.online is a useless, fake search engine. As a rule, such search engines are promoted through potentially unwanted applications (PUAs), browser hijackers. Apps of this type promote fake search engines by changing certain browser's settings. It is common that they gather browsing data and/or other information as well. Quite often users download and install potentially unwanted apps unknowingly, accidentally.

Boy Scouts of America (BSA) filed for Chapter 11 bankruptcy to achieve two key objectives ...

Stimați și dragi timișoreni

A University at Buffalo-led research team is studying the details of how enzymes perform their job. The focus of the project is on understanding the molecular interactions that enable enzymes to accelerate chemical reactions.

Marivi Fernandez-Serra is a professor in the Department of Physics and Astronomy at Stony Brook University.

Dear Shim Shim, I hate this month, it's so miserable and even more so cos you passed on Halloween eve. I remember it all so vividly, your loss and Zeusy's

I lost my Taz April 20th. He was my best friend and companion. He looked at me with so much love. My children and grandchildren live so far away. He

Truth Hurts Lizzo Why men great ’til they gotta be great? Woo I just took a DNA test, turns out I’m 100% that bitch Even when I’m crying crazy Yeah, I got boy problems, that’s the human in me Bling bling, then I solve ’em, that’s the goddess in me You coulda had a bad […]

Feeling isolated? Perhaps a crossword puzzle will help. Click on the image to do the crossword puzzle on line, or click here for a printable pdf. If you do the puzzle on line, you can click the “submit” button to bring up a form where you can enter your name and submit your solution. I […]

Группа Gorillaz представила песню How Far?, которая была написана вместе с барабанщиком Тони Алленом и посвящена ему.

For well over a decade we've talked about the many problems that arise when copyright is compared to "property" -- and people try to simply move over concepts from physical, tangible property into the world of digital. A key aspect of this: when you "purchase" something digital online, is it really a "purchase" or is it a "license" (especially a license that could be revoked)? If it was a true "purchase" then you should own it and the seller shouldn't be able to take it back. But in practice, over and over and over again, we've seen stories of people having things they supposedly "bought" disappear. The situation is so crazy that we've referred to it as Schrödinger's Download, in that many copyright holders and retailers would like the very same thing to be a "sale" some of the time, and a "license" some of the time (the "times" for each tend to be when it hurts the consumers the most). This has, at times, seeped into physical goods, where they've tried to add "license agreements" to physical products. Or, worse, when some copyright folks claimed that buying a DVD means you don't actually own what you bought, but rather are merely "purchasing access" to the content, and that could be revoked.

Anyway, I'm amazed that we don't see more lawsuits about this kind of thing -- but one was recently filed in California. Someone named Amanda Caudel is suing Amazon for saying that you've "purchased" a video download, which Amazon might disappear from your library whenever it wants. As the lawsuit makes clear, Amazon directly says that you are buying the movie (as opposed to renting it). From the lawsuit filing itself:

And, they point out, in your account there's a listing of "Your Video Purchases & Rentals." But, the lawsuit claims, what you purchase doesn't seem to behave like a real purchase:

Reasonable consumers will expect that the use of a “Buy” button and the representation that their Video Content is a “Purchase” means that the consumer has paid for full access to the Video Content and, like any bought product, that access cannot be revoked.

Unfortunately for consumers who chose the “Buy” option, this is deceptive and untrue. Rather, the ugly truth is that Defendant secretly reserves the right to terminate the consumers’ access and use of the Video Content at any time, and has done so on numerous occasions, leaving the consumer without the ability to enjoy their already-bought Video Content.

Defendant’s representations are misleading because they give the impression that the Video Content is purchased – i.e. the person owns it - when in fact that is not true because Defendant or others may revoke access to the Video Content at any time and for any reason.

In so representing the “Purchase” of Video Content as true ownership of the content, Defendant took advantage of the (1) cognitive shortcuts made at the point-of-sale, e.g. Rent v. Buy and (2) price of the Video Content, which is akin to an outright purchase versus a rental.

Though some consumers may get lucky and never lose access to any of their paid-for media, others may one day find that their Video Content is now completely inaccessible. Regardless, all consumers have overpaid for the Video Content because they are not in fact owners of the Video Content, despite have paid extra money to “Buy” the product.

The plaintiff (or rather, her lawyers) are trying to make this a class action lawsuit, and are arguing that (among other things) this is false advertising. I am, not surprisingly, sympathetic to the plaintiff -- and remain disappointed at how copyright and similar restrictions are being used to chip away at ownership and actual property rights. That said... I'm not that optimistic the case will get very far. In the past, companies have been able to wiggle out of similar claims, and I'm pretty sure that Amazon tries to push disputes like this to binding arbitration, meaning that the lawsuit may be dead on arrival.

Still, it's yet another reminder of how copyright is chipping away at real property.

Just as in other types of victimization, victims of cybercrime can experience serious consequences, emotional or not. First of all, a repeat victim of a cyber-attack might face serious financial or emotional hardship. These victims are also more likely to require medical attention as a consequence of online fraud victimization. This means repeat victims have a … Continue reading Three Paper Thursday: Exploring the Impact of Online Crime Victimization →

This dinner recipe has become my new favorite! It's easy, fast and tastes as great as the local taqueria!

craving more? check out TasteSpotting

A family recipe for a simple, moist chocolate zucchini cake made delicious by grated zucchini, oil, buttermilk and cocoa.

craving more? check out TasteSpotting

Multinationals' UK arms pair up to take on Voda and former state-owned telco

Telcos Telefónica and Liberty Global today confirmed plans to join their O2 UK and Virgin Media subsidiaries into one combined entity in a deal analysts branded a "blockbuster merger".…

Things will change forever, nods ex-Facebooker Alex Stamos

Video conferencing software biz Zoom has bought Keybase in a surprise move just weeks after hiring Facebook's one-time CSO.…

Secarma may be next for Inflexion buyout

Cloud hosting biz UKFast's founders, Laurence and Gail Jones, have "exited the business" as a private equity firm ups its stake – all as UKFast itself starts eyeing up Jones-owned infosec biz Secarma.…

Tune in online this month to find out how to protect your business from data extortionists

Webcast It's been "the year of ransomware" for about the past three years. And while you may be tired of hearing about the trend and just getting used to the reality, you may also like to remember: instances of attacks are climbing – quickly – and we’re now reaching a level where more than half of ransomware schemes result in a business paying out.…

John Cena!* Online resources only for free and end users due to the 'unprecedented period'

Video conferencing darling of the hour, Zoom, has tightened up support rules in order to "better serve" users.…

Despite you know what, little evidence of a rush to new racks

Equinix has posted its Q1 FY2020 results for the period ending March 31st, along with some interesting insights into how the COVID-19 pandemic has impacted data centre consumption.…

Revisit what it’s like to run a PDP-10 and be eaten by a grue

Source code for seminal adventure game Zork, dating back to 1977 and recovered from MIT tapes, was published this week on GitHub.…

-Album Details- Title: The Legend of Zelda: Link’s Awakening Original Soundtrack Publisher: Nippon Columbia Catalog Number: COCX-41117~20 Release Date: March 18th, 2020 Ripped by: Razakin -Info- Soundtracks to the new Switch and the way better Game Boy versions of Link’s Awakening. Enjoy. Purchase Link(s) CDJapan

A review by SomeRandomHEFan (46). One of Humongous Entertainment's weaker attempts at conventional edutainment

Индийский инсайдер Судханшу Амбхоре (Sudhanshu Ambhore)‏ продолжает публиковать подробности о новом смартфоне Realme X3 SuperZoom.

Компания Meizu провела в Китае мероприятие, на котором анонсировала свою новую флагманскую линейку смартфонов — Meizu 17.

По словам производителя, Flyme 8.1, по сравнению с Flyme 8, получила более 300 улучшений и оптимизаций.

Компания Meizu вчера, кроме флагманских смартфонов, представила ещё свои обновлённые накладные Bluetooth-наушники Meizu HD60.

На корпусе есть небольшой дисплей, на котором отображается информация об уровне заряда аккумулятора и выходной мощности.

Power reliable ceiling followers are a wonderful method to make your home much more inviting, visually pleasing and also, as an added bonus offer, reduced your overall house power air conditioning bill if you currently have a home cooling system.… Continue Reading →

The Miami Beach danger zone for mosquitoes carrying Zika virus is expanding. This isn't just about microcephaly in developing fetuses. Since Zika attacks neural progenitor cells it might cause lasting damage in adults too. A case of acute sensory polyneuropathy in an adult caused symptoms that lasted for months. It is suspected that Zika causes inflammation of sensory nerves and possibly an auto-immune response. So Zika is bad. What should we do about it? Wipe out the mosquitoes that carry it. Totally drive them to extinction. These mosquitoes are invasive in the Western Hemisphere. If a mosquito causes major health problems for the human species we should just wipe it out. Wiping out a mosquito species could be done with...

The message is Zoom and gloom!

Contes de fées aux enfants - Au zoo avec Sam et Lucca.

On accorde "The World of Art Award" (WAA) aux artistes, aux galeries et aux musées qui poursuivent les "meilleures pratiques" dans l'art et la culture. Cette concurrence cherche à attirer dies artistes, galeries, les musées qui redéfinissent des normes de l'excellence d'art. Ceux qui défie des trends et des tendances existantes dans l'art et la culture.

Alterations in calcium signaling in pancreatic acinar cells can result in pancreatitis. Although pressure changes in the pancreas can elevate cytosolic calcium (Ca2+) levels, it is not known how transient pressure-activated elevations in calcium can cause prolonged calcium changes and consequent pancreatitis. In this issue of the JCI, Swain et al. describe roles for the mechanically activated plasma membrane calcium channels Piezo1 and transient receptor potential vanilloid subfamily 4 (TRPV4) in acinar cells. The authors used genetic deletion models and cell culture systems to investigate calcium signaling. Notably, activation of the Piezo1-dependent TRPV4 pathway was independent of the cholecystokinin (CCK) stimulation pathway. These results elegantly resolve an apparent discrepancy in calcium signaling and the pathogenesis of pancreatitis in pancreatic acinar cells.

Elevated pressure in the pancreatic gland is the central cause of pancreatitis following abdominal trauma, surgery, endoscopic retrograde cholangiopancreatography, and gallstones. In the pancreas, excessive intracellular calcium causes mitochondrial dysfunction, premature zymogen activation, and necrosis, ultimately leading to pancreatitis. Although stimulation of the mechanically activated, calcium-permeable ion channel Piezo1 in the pancreatic acinar cell is the initial step in pressure-induced pancreatitis, activation of Piezo1 produces only transient elevation in intracellular calcium that is insufficient to cause pancreatitis. Therefore, how pressure produces a prolonged calcium elevation necessary to induce pancreatitis is unknown. We demonstrate that Piezo1 activation in pancreatic acinar cells caused a prolonged elevation in intracellular calcium levels, mitochondrial depolarization, intracellular trypsin activation, and cell death. Notably, these effects were dependent on the degree and duration of force applied to the cell. Low or transient force was insufficient to activate these pathological changes, whereas higher and prolonged application of force triggered sustained elevation in intracellular calcium, leading to enzyme activation and cell death. All of these pathological events were rescued in acinar cells treated with a Piezo1 antagonist and in acinar cells from mice with genetic deletion of Piezo1. We discovered that Piezo1 stimulation triggered transient receptor potential vanilloid subfamily 4 (TRPV4) channel opening, which was responsible for the sustained elevation in intracellular calcium that caused intracellular organelle dysfunction. Moreover, TRPV4 gene–KO mice were protected from Piezo1 agonist– and pressure-induced pancreatitis. These studies unveil a calcium signaling pathway in which a Piezo1-induced TRPV4 channel opening causes pancreatitis.

Curing HIV infection will require the elimination of a reservoir of infected CD4+ T cells that persists despite HIV-specific cytotoxic T cell (CTL) responses. Although viral latency is a critical factor in this persistence, recent evidence also suggests a role for intrinsic resistance of reservoir-harboring cells to CTL killing. This resistance may have contributed to negative outcomes of clinical trials, where pharmacologic latency reversal has thus far failed to drive reductions in HIV reservoirs. Through transcriptional profiling, we herein identified overexpression of the prosurvival factor B cell lymphoma 2 (BCL-2) as a distinguishing feature of CD4+ T cells that survived CTL killing. We show that the inducible HIV reservoir was disproportionately present in BCL-2hi subsets in ex vivo CD4+ T cells. Treatment with the BCL-2 antagonist ABT-199 was not sufficient to drive reductions in ex vivo viral reservoirs when tested either alone or with a latency-reversing agent (LRA). However, the triple combination of strong LRAs, HIV-specific T cells, and a BCL-2 antagonist uniquely enabled the depletion of ex vivo viral reservoirs. Our results provide rationale for novel therapeutic approaches targeting HIV cure and, more generally, suggest consideration of BCL-2 antagonism as a means of enhancing CTL immunotherapy in other settings, such as cancer.