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Charge-transfer inclusion complex formation of the tropylium cation with prism[6]arenes

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00423J, Communication
Guojiao Zhang, Channi Cheng, Zhengxiang Li, Dezhi Zhao, Chengyou Han
We report that charge-transfer (CT) inclusion complexes were formed between prism[6]arenes and tropylium cation. Additionally, the CT complex showed Cl/Ag+ responsiveness which can be easily monitored by the naked eye.
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Cu(OTf)2/HFIP catalyzed regioselective cycloisomerization of indole-C3-functionalized alkynols to carbazoles

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00421C, Communication
Srinivasarao Yaragorla, Tabassum Khan, Sayonika Chakroborty
We report here a simple and atom economic cycloisomerization reaction of indole-tethered alkynols for constructing diverse carbazoles via 1,2-alkly migration using Cu(OTf)2/HFIP as the excellent promoter system.
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Photoproperties of Favipiravir and their 6-Substituted Analogues: Fluorescence Controlled through Halogen Substitution and Tautomerism

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00397G, Paper
Angel H Romero, Marcos Couto, Ivan E Romero, German Fuentes, Matías N. Möller
Herein, we showed the photophysical properties of the favipiravir and their 6-substituted analogues. Also, we interpreted the origin of the fluorescence of the favipiravir and their 6-substituted analogues as function...
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Measuring local pH at interfaces from molecular tumbling: A concept for designing EPR-active pH-sensitive labels and probes

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00167B, Paper
Open Access
Maxim A. Voinov, Nicholas Nunn, Roshan Rana, Atli Davidsson, Alex I. Smirnov, Tatyana I. Smirnova
EPR-based local pH measurements based on changes in rotational dynamics of spin-bearing molecules upon protonation.
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A Highly Diastereoselective One-Pot Ugi/Radical Spirocyclization/Aza-Michael Addition Sequence

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00610K, Communication
Chandra Volla, Salman Khan, Abhradeep Chatterjee, Akshay Murali Nair
We hereby report a highly diastereoselective synthesis of chalcogenated azaspirotricycles via a one-pot Ugi/spirocyclization/ aza-Michael addition sequence. The reaction proceeded via a key visible light mediated spirocyclization step under mild,...
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N-Functionalization of beta-aminophosphonates; Cytotoxic effect of the new derivatives

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00243A, Paper
György Keglevich, Petra Regina Varga, Emőke Dinnyési, Zsuzsanna Szalai, Szilvia Bősze, Rita Oláhné Szabó, Laszlo Drahos, Konstantin Karaghiosoff
Beta-Aminophosponates obtained by the Michael addition of primary amines to the double bond of diethyl vinylphosphonate proved to be suitable starting materials (amine components) in the Kabachnik–Fields reaction with formaldehyde...
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The Hobbit Experience 2014: Adding WebRTC gameplay to the Hobbit Experience

Learn how North Kingdom built an immersive multimedia experience optimized for modern mobile browsers using Web RTC




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As the price of aviation turbine fuel soars, airlines’ finances spin out of control




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‘The challenge was in getting the aircraft’s custom clearance’

Private jet operator JetSetGo’s CEO Kanika Tekriwal describes the intricacies of directly importing and leasing an aircraft




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Walking through a new airport experience

Automation and biometrics will be the norm rather than the exception at leading airports in the pandemic world




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Breaking down airline engineering and maintenance

An aircraft has three critical phases; induction, in-service and redelivery




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Insolvency of aircraft operator: default remedies.

India should adopt Cape Town Convention as part of the domestic legal framework.




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Airlines’ performance metrics may need an overhaul

It may be time to revisit RASK, CASK metrics; benchmarking based on cost drivers can boost an airline’s performance




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Why opening the emergency door mid-flight is not possible




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Compliance with regulation: Staying ahead is key




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Zomato users can now schedule order 2 days in advance

Zomato’s order scheduling is available at more than 35,000 restaurants across 30 cities




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Sarvam AI launches Sarvam 1 for Indic languages

The custom training corpus, Sarvam-2T comprised of 20 percent datasets in Hindi as well as English and programming languages so the AI model can perform multilingual tasks




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Hong Kong unveils responsible AI framework for financial sector

Hong Kong’s responsible AI framework comes amid increasing international competition and tensions affecting access to AI technology




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Apple Intelligence launches the iPhone into the AI era

Apple has released a free software update that will inject its first dose of artificial intelligence into its iPhone 16 line-up as the trendsetting company tries to catch up with technology’s latest craze




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Meta builds AI search engine to cut Google, Bing reliance, the Information reports

The Facebook-owner currently relies on Google and Bing search engines to give users answers on news, stocks and sports




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Microsoft Teams to launch threaded conversations, combined chats and channels features

The app has also added other changes in the interface so users can organise their chats better




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OpenAI CEO Sam Altman says next big AI model launch pushed due to compute challenges

Altman also said that the next update for DALL-E was still in the works with no release date yet




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Out-of-pocket expenditure on health in Kerala is highest in country despite increased State investments

National Health Accounts figures show the per capita out-of-pocket expenditure on health in Kerala stands at ₹7,889. However, Kerala also tops the list when it comes to the per capita government spending on health, at ₹4,338




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WHO certifies Egypt as malaria-free; calls it ‘historic feat’ ending ancient scourge

Globally, 44 countries and one territory have now been certified as malaria-free




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Acute Flaccid Paralysis surveillance as a crucial defence against polio in India | Explained

India needs to continue efforts to maintain its polio-free status, and AFP surveillance has to remain a cornerstone of its strategy




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Why did the Centre sanction a 50% hike in prices of commonly-used drugs?

According to the government the recent 50% hike in prices of eight drugs was sanctioned keeping in mind the larger public interest and to ensure continued availability of drugs




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What is stereotactic radiation therapy for prostate cancer? How does it compare to other treatments?

Stereotactic radiotherapy uses high doses of radiation to target and kill cancer cells; it uses newer machines that can deliver very focused radiation beams




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Bridging the gap in mental healthcare services: NGOs launch dementia clinics in Hyderabad’s slums

India continues to grapple with a dearth of mental healthcare services, even as the number of persons with dementia is expected to rise over the next two decades




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National Pharmaceutical Pricing Authority directs firms to cut prices of three anti-cancer drugs

Govt. had earlier scrapped customs duty on Trastuzumab, Osimertinib and Durvalumab and also reduced GST rates on them




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World Stroke Day: NIMHANS study finds that part of sleep apnoea burden is a consequence of stroke

Most patients with stroke are not evaluated for sleep apnea; this is an issue that needs to be addressed by the scientific community, doctors at NIMHANS, Bengaluru said




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As breast cancer incidence rises, doctors raise importance of early detection, need for women to be breast aware

Chennai accounts for highest crude incidence rate of breast cancer in T.N., data shows; a number of factors have led to this, say doctors




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What is breast density and how is it associated with cancer? Explained

Breast density matters because of two main reasons: it may make it harder to detect signs of cancer on a mammogram, and it is linked with an increased risk of breast cancer




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How to overcome your device dependency and manage a successful digital detox

There are four key strategies that are key to helping you achieve a healthier digital balance: replacement practices, social bonds, mindfulness and viewing digital well-being as a journey




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ICMR announces ‘First in the World Challenge’ to encourage scientists to find innovative ideas to tackle health issues

The Council said that the scheme proposes to foster novel, out of the box, futuristic ideas, new knowledge generation, discovery / development of breakthrough health technologies




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Glioblastoma: why immunotherapy may offer hope for brain cancer patients

Recent trials have shown that immunotherapy can safely be delivered through injections into the cerebrospinal fluid; scientists are now exploring how to adapt these methods to penetrate the tumour more effectively




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Bengaluru start-up strives to bridge India’s genomics data gap to aid precision oncology

The company, 4baseCare, has come up with a gene panel for the Indian population after extensive research. This, according to the founders, will allow doctors to provide more evidence-based and data-backed treatment for cancer patients in the country




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'Once in a blue moon you get a lottery like Animal'

'It has never happened that all Top 5 songs on Spotify are from one film. On the Ormax list, the Top 9 are from Animal.''The music is good, sure. But everything has taken off with Animal the film.'




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'I have danced with Sushmita Sen!'

'She got really close, and I was like, oh Miss Universe and me dancing!'




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'Women don't have to only sing and dance'

'When you are new, you don't know how the industry works'. 'But when you know where you are headed, the possibilities of being conned or facing unpleasant instances is reduced.'




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'I can feel Irrfan's presence'

'My respect for Irrfan has grown 100 times now when he is no longer with us.'




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Making Prabhas And Diljit Dance

'Diljit and Prabhas are so similar -- very humble, down-to-earth, extremely shy introverts and at the same time, extremely talented guys.'




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The Difference Between Fawad And SRK

'I think because India is a bigger country and Bollywood is such a well-oiled machine, the star thing has become so much bigger than the actor thing.'




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'Happy Performances Are Usually Ignored'

'If people think that films that are happy or light, or comedy or romance are not substantial, that's not true.''I was really happy when this award was given for Thiruchitrambalam because it highlights that.'




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'The Audience Can't Be Tricked'

'In the audience's mind there is no urgency to go see a film in the theatre.''If you pay for social media buzz it does not convert into bums on seats.'




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'The Appetite For Horror Has Increased'

'How to hold people's attention is challenging.'





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A follow up to obtaining 60fps scrolling performance

60fps scrolling article got quite a few people excited but also a few smart people to point out some flaws in the approach. I was planning to just update the original article but I’ve compiled so much info about this topic that I thought it would be better to do a follow up article and … Continue reading "A follow up to obtaining 60fps scrolling performance"




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OnePlus 13 launched with Snapdragon 8 Gen 4 SoC: Price details, battery and other specifications

While the OnePlus 13 has only been revealed in China so far, speculations are that it will arrive on the global market in the coming months. In India, the phone is expected to be launched in January 2025.




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Sustainability Meets Innovation via uPVC: Industry expert shares experience

The rise of uPVC in the Indian construction sector can be attributed to several factors. Unlike traditional materials such as wood and aluminum, uPVC offers excellent thermal insulation, reducing energy consumption for heating and cooling.




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The Role of Artificial Intelligence in Enhancing Software Performance and Security

Sachin Samrat Medavarapu, a recognized leader in AI-enhanced security and performance optimization, has built an impressive career marked by a series of significant achievements.