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A dozen industrial smart cities worth ₹28,602 cr get CCEA approval

Projects to be completed by 2027, attract investment of ₹1.5 lakh crore, general 10 lakh direct jobs, says Piyush Goyal




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Data | The risk of small States’ heavy reliance on the Union government

Small States must prioritise raising their own revenue to reduce their vulnerabilities in the future




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‘Dynamite’ Daniel Dubois smashes his way into the heavyweight world title scene

After destroying fan favourite Anthony Joshua’s redemption arc with a brutal hammering, the IBF champion’s future looks bright. He could await the winner of the Usyk-Fury fight, where the WBA, WBO and WBC belts are on the line, for an opportunity to become the undisputed champion




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A portable fluorescence detection device based on a smartphone employing carbon nanodots for Mn2+ sensing

Anal. Methods, 2024, 16,2101-2110
DOI: 10.1039/D4AY00027G, Paper
Pijika Mool-am-kha, Samuch Phetduang, Kessarin Ngamdee, Chayada Surawanitkun, Xiang-Kui Ren, Wittaya Ngeontae
A low-cost, portable, and low-energy consumption fluorescence reader-based smartphone device employing carbon nanodots for detection of Mn2+.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of L-lactate

Anal. Methods, 2024, 16,2077-2084
DOI: 10.1039/D4AY00041B, Paper
Wenjuan Wang, Danrong Chen, Yujiao Cai, Zijing Liu, Hongfen Yang, Hongbin Xie, Jinquan Liu, Shengyuan Yang
Here, we show a paper-based POCT sensor based on lactate dehydrogenase-mediated alginate gelation combined with visual distance reading and smartphone-assisted colorimetric dual-signal analysis to determine the concentration of L-lactate in yogurt samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Luminescent and time-resolved determination of gemifloxacin mesylate in pharmaceutical formulations and spiked blood plasma samples using a lanthanide complex as a probe

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00236A, Paper
Gasser M. Khairy, Rania M. Goda, Zeinab M. Anwar, Mohamed M. Aboelnga, Axel Duerkop
A new luminescent europium probe for the determination of the antibiotic gemifloxacin is presented. Time-resolved luminescence enables its quantitation in pharmaceutical formulations and blood samples.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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LAMP-based hydrogen ion selective electrochemical sensor for highly sensitive detection of Mycoplasma pneumoniae

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00341A, Paper
Huiqing Wang, Yang Li, Lin Tian, Xinyi Li, Qian Gao, Yaru Liu, Cuiping Ma, Qing Wang, Chao Shi
An urgent need for a concise and rapid detection method for Mycoplasma pneumoniae is required due to its severe impact on human’s health. To meet such a need, this study...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A complementary method with PFBBr-derivatization based on a GC-EI-MS platform for the simultaneous quantitation of short-, medium- and long-chain fatty acids in murine plasma and feces samples

Anal. Methods, 2024, 16,2330-2339
DOI: 10.1039/D3AY02271D, Paper
Hong-Xu Zhou, Qing Jiang, Xin He, Xian Fu, Jun-Yan Liu
Fatty acids (FAs) are essential molecules in all organisms and are involved in various physiological and pathophysiological processes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00487F, Paper
Jinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang Liu
Small extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The not-so-smart use of mobiles




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Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia

RSC Med. Chem., 2024, 15,3495-3506
DOI: 10.1039/D4MD00275J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. Russell
The optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.
The content of this RSS Feed (c) The Royal Society of Chemistry




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SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells via the AKT/mTOR signaling pathway

RSC Med. Chem., 2024, 15,3460-3468
DOI: 10.1039/D4MD00405A, Research Article
Xiaoqin Luo, Jin Wang, Ruichang Wang, Jiabing Lian, Mengnan Guo, Hongrui Zhou, Mengxue Zhang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli Bi
Schematic of proposed mechanism for the treatment of the SLL-1A-16 inhibiting the proliferation in NSCLC.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design, synthesis and biological evaluation of a novel PSMA–PI3K small molecule drug conjugate

RSC Med. Chem., 2024, 15,3485-3494
DOI: 10.1039/D4MD00246F, Research Article
Shouguo Peng, Haixia Li, Weilu Cui, Tianning Xiong, Jiaqi Hu, Haixiang Qi, Songwen Lin, Deyu Wu, Ming Ji, Heng Xu
A novel PSMA–PI3K small molecule drug conjugate has been prepared, highlighting its potential in targeted cancer therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024)

RSC Med. Chem., 2024, 15,3371-3394
DOI: 10.1039/D4MD00384E, Review Article
Debasis Das, Lingzhi Xie, Jian Hong
Prospects of novel fourth-generation EGFR-TKIs overcoming C797S-mediated resistance in non-small cell lung cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Sidechain structure–activity relationships of cyclobutane-based small molecule αvβ3 antagonists

RSC Med. Chem., 2024, 15,3616-3624
DOI: 10.1039/D4MD00306C, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Adam Throup, Manar Saleh Zraikat, Andrew Gordon, Shohreh Jafarinejad Soumehsaraei, Kathrin D. Haase, Laurence H. Patterson, Patricia A. Cooper, Katherine Hanlon, Paul M. Loadman, Mark Sutherland, Steven D. Shnyder, Helen M. Sheldrake
Cyclobutanes provide a versatile scaffold for the synthesis of small molecule integrin antagonists with good metabolic stability and in vivo tolerability.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00673A, Review Article
Juhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong Jun
Potential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00553H, Research Article
Stefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro Cosconati
Non-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Small-scale handloom park to come up at Sengunthapuram

Ministers R. Gandhi and S.S. Sivashankar inspect the 13,205 sq. ft. site belonging to the Tamil Nadu Cotton Corporation at Sengunthapuram




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Site identified for small-scale handloom park in Karur




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Design water-smart cities

We need an army of people who will ensure the protection of water bodies, and who will strive to create a water-literate community.




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Smart water solution

A bunch of Chennai students are making Paani Genie, a 90-litre water container that can be rolled along.




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How radio waves can power smart cities 

Practically omnipresent, thanks to human activity, radio frequency is the new area of focus for energy harvesting technology



  • Science and Technology

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Craft beer: Growth in small batches

A favourite with millennials and GenZ for their artisanal products, microbreweries are set to expand, backed by VCs 




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Cashing out of a business, smartly

The book draws upon diverse experiences of entrepreneurs to highlight the need for an exit strategy




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Need for climate-smart agriculture in India

Climate-smart agriculture has the potential to assure food security, empower farmers, and protect our delicate ecosystems




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How can small-scale farmers benefit from trees on farms?

The adoption of agroforestry at scale in India by smallholders is currently stymied by ecological and socio-economic factors




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Mangrove restoration in T.N. makes a small but steady progress

The Tamil Nadu Forest Department and non-governmental organisations are working to restore mangroves at various sites of the Ennore-Pulicat wetlands. In the meantime, the National Centre for Coastal Research has identified land available for restoration in Cuddalore, Tiruvarur, Thanjavur, Pudukkottai, Ramanathapuram, and Thoothukudi




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ICAR team makes tool small enough to edit plant genomes

In a genome-editing landscape low on options for plants, the new tool has scientists enthused about its applications in agriculture




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By 2021, India to have 810 m smartphone subscriptions




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‘India is a bright spot in global smartphone scene’




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Random field reconstruction of three-phase polymer structures with anisotropy from 2D-small-angle scattering data

Soft Matter, 2024, 20,8493-8504
DOI: 10.1039/D4SM00721B, Paper
Open Access
Stephen Kronenberger, Nitant Gupta, Benjamin Gould, Colin Peterson, Arthi Jayaraman
We present a computational method to analyze 2D small-angle scattering data from three-phase soft materials systems with structural anisotropy and output representative real-space structures of the three phases.
The content of this RSS Feed (c) The Royal Society of Chemistry




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pH and glucose dual-responsive phenylboronic acid hydrogels for smart insulin delivery

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM01004C, Paper
Keke Yang, Hou Bo, Dewei Ma, Mingwei Peng, Qinglong Liu, Ziwen Heng, Zhongwei Gu, Xuhan Liu, Siyuan Chen
Phenylboronic acid (PBA) is a widely exploited glucose-sensitive element for constructing glucose-responsive hydrogels to enable smart insulin delivery.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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For the mismatched fashionista




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A smart guide to fitness

If you get it right, getting fit is that much easier




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Editorial. Small-scale commercial nuclear reactors, the way forward

It is increasingly being realised that achieving net-zero is not possible without nuclear energy




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Suryoday Small Finance Bank’s net profit dips 10% in Q2FY25 to ₹45 cr

Net interest margin rose to 9.7 per cent in Q2FY25 against 9.4 per cent in Q2FY24



  • Money & Banking

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Delhi Insurance Ombudsman Office clears all complaints of 2023-24

All 3,443 complaints received in 2023-24 have been disposed, says Sunita Sharma, Insurance Ombudsman 



  • Money & Banking

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Functional equations and how to solve them [electronic resource] / Christopher G. Small

New York, N.Y. : Springer Science, 2007




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Putting the smartphone in its place

A mathematics teacher turned counsellor is on a mission to promote digital well-being across classrooms and homes




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Positive response to Small and Medium REITs: SEBI Chief

There is an imbalance of power between large institutions and small investors, and regulations have helped foster trust in the system, Says Madhabi Puri Buch




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EFC gets SEBI nod for India’s first small & medium REIT IPO 

With plans for a ₹500 crore IPO through its subsidiary, EFC REIT, the company aims to enhance its investment management and commercial real estate operations.




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Art in small packages

Watch A Short Film Festival on September 5




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I am…Padmakumar – Metal craftsman




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Retraction: Fabrication of novel quantum dots for the estimation of COVID-19 antiviral drug using green chemistry: application to real human plasma

RSC Adv., 2024, 14,35696-35696
DOI: 10.1039/D4RA90133A, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Baher I. Salman, Adel Ehab Ibrahim, Sami El Deeb, Roshdy E. Saraya
The content of this RSS Feed (c) The Royal Society of Chemistry




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Retraction: Highly sensitive cadmium sulphide quantum dots as a fluorescent probe for estimation of doripenem in real human plasma: application to pharmacokinetic study

RSC Adv., 2024, 14,35992-35992
DOI: 10.1039/D4RA90134G, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Marwa F. B. Ali, Baher I. Salman, Samiha A. Hussein, Mostafa A. Marzouq
The content of this RSS Feed (c) The Royal Society of Chemistry




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Nana Patole hints on more BJP leaders to join Congress, small parties to go solo

Shishupal Patle’s entry ahead of the Assembly election is being seen as a way to strengthen Congress’s influence in the constituency, which falls under the Vidharbha region of Maharashtra




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Teenage boy stabbed by classmate in Udaipur succumbs to injuries

Tension prevails after crowd gathered outside hospital and other areas; police resort to lathi charge; more force sent to maintain law and order; prohibitory orders remain




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PIX: Root, Brook smash tons; England pile on the runs

Joe Root and Harry Brook's centuries powered England's strong reply on Day 3 of the first Test in Multan.




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2nd T20 PIX: Buttler smashes England to thumping win!

England skipper Jos Buttler hammered a superb 83 off 45 balls to steer his side to a seven-wicket victory in the second Twenty20 international against West Indies.




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Trump wants to be 'dictator', won't be good for ties with India: Congressman Shri Thanedar on US polls

He further underscored the importance of the Indian-American vote in the upcoming US Presidential elections, while noting the growing support for Kamala Harris in the crucial swing state of Michigan