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Punjab's first school ready for 1,000-bed isolation centre




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Punjab Cong to raise national flag to protest Centre's bias




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Raise tricolour on May 1 to protest against Centre's discrimination: Punjab Cong asks people




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Two hostels of Panjab University to be converted into quarantine centres




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Shopping centres body seeks reopening of malls




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Ban on entry of unregistered Keralites through Talapady

Surge in number of returnees without registration




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COVID-19 | Madurai colleges, hostels turn isolation centres

This has been done to tackle any explosion of COVID-19 cases, says Collector T. G. Vinay




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The Centre will need to nurse the Constitution and India back to good health




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Location of Cu2+ in CHA zeolite investigated by X-ray diffraction using the Rietveld/maximum entropy method

Rietveld/MEM analysis applied to synchrotron powder X-ray diffraction data of dehydrated CHA zeolites with catalytically active Cu2+ reveals Cu2+ in both the six- and eight-membered rings in the CHA framework, providing the first complete structural model that accounts for all Cu2+. Density functional theory calculations are used to corroborate the experimental structure and to discuss the Cu2+ coordination in terms of the Al distribution in the framework.






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New species of bat named from central coastal Ecuador

A diminutive bat with cinnamon-brown coloring collected in 1979 in Ecuador by mammalogist Don Wilson of the Smithsonian’s National Museum of Natural History represents a new species a recent paper in the journal “Mammalian Biology” has revealed.

The post New species of bat named from central coastal Ecuador appeared first on Smithsonian Insider.




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Green-headed Tanager (Tangara seledon) of east-central South America

A description and photos of the green-headed tanager (Tangara seledon), a bird native to east-central South America, can be found in the Species of the […]

The post Green-headed Tanager (Tangara seledon) of east-central South America appeared first on Smithsonian Insider.




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Deadly amphibian disease detected in the last disease-free region of Central America

Smithsonian scientists have confirmed that chytridiomycosis, a rapidly spreading amphibian disease, has reached a site near Panama’s Darien region. This was the last area in the entire mountainous neotropics to be free of the disease. This is troubling news for the Panama Amphibian Rescue and Conservation Project, a consortium of nine U.S. and Panamanian institutions that aims to rescue 20 species of frogs in imminent danger of extinction.

The post Deadly amphibian disease detected in the last disease-free region of Central America appeared first on Smithsonian Insider.




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Event Horizon Telescope Reveals Magnetic Fields at Milky Way’s Central Black Hole

Most people think of black holes as giant vacuum cleaners sucking in everything that gets too close. But the supermassive black holes at the centers […]

The post Event Horizon Telescope Reveals Magnetic Fields at Milky Way’s Central Black Hole appeared first on Smithsonian Insider.




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Screwed up DNS entry




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Actin waves transport RanGTP to the neurite tip to regulate non-centrosomal microtubules in neurons [RESEARCH ARTICLE]

Yung-An Huang, Chih-Hsuan Hsu, Ho-Chieh Chiu, Pei-Yu Hsi, Chris T. Ho, Wei-Lun Lo, and Eric Hwang

Microtubule (MT) is the most abundant cytoskeleton in neurons and controls multiple facets of their development. While the MT-organizing center (MTOC) in mitotic cells is typically located at the centrosome, MTOC in neurons switches to non-centrosomal sites. A handful of cellular components have been shown to promote non-centrosomal MT (ncMT) formation in neurons, yet the regulation mechanism remains unknown. Here we demonstrate that the small GTPase Ran is a key regulator of ncMTs in neurons. Using an optogenetic tool that enables light-induced local production of RanGTP, we demonstrate that RanGTP promotes ncMT plus-end growth along the neurite. Additionally, we discovered that actin waves drive the anterograde transport of RanGTP. Pharmacological disruption of actin waves abolishes the enrichment of RanGTP and reduces growing ncMT plus-ends at the neurite tip. These observations identify a novel regulation mechanism of ncMTs and pinpoint an indirect connection between the actin and MT cytoskeletons in neurons.




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Chondrosarcoma-associated gene 1 (CSAG1) maintains the integrity of the mitotic centrosome in cells with defective p53 [RESEARCH ARTICLE]

Hem Sapkota, Jonathan D. Wren, and Gary J. Gorbsky

Centrosomes focus microtubules to promote mitotic spindle bipolarity, a critical requirement for balanced chromosome segregation. Comprehensive understanding of centrosome function and regulation requires a complete inventory of components. While many centrosome components have been identified, others may yet remain undiscovered. We have used a bioinformatics approach, based on "guilt by association" expression to identify novel mitotic components among the large group of predicted human proteins that have yet to be functionally characterized. Here we identify Chondrosarcoma-Associated Gene 1 (CSAG1) in maintaining centrosome integrity during mitosis. Depletion of CSAG1 disrupts centrosomes and leads to multipolar spindles more effectively in cells with compromised p53 function. Thus, CSAG1 may reflect a class of "mitotic addiction" genes whose expression is more essential in transformed cells.




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C3G localizes to mother centriole dependent on cenexin, and regulates centrosome duplication and primary cilia length [RESEARCH ARTICLE]

Sanjeev Chavan Nayak and Vegesna Radha

C3G (RapGEF1) plays a role in cell differentiation and is essential for early embryonic development in mice. In this study, we identify C3G as a centrosomal protein colocalizing with cenexin at the mother centriole in interphase cells. C3G interacts through its catalytic domain with cenexin, and they show interdependence for localization to the centrosome. C3G depletion caused a decrease in cellular cenexin levels. Centrosomal localization is lost as myocytes differentiate to form myotubes. Stable clone of cells depleted of C3G by CRISPR/Cas9 showed the presence of supernumerary centrioles. Overexpression of C3G, or a catalytically active deletion construct inhibited centrosome duplication. Cilia length is longer in C3G knockout cells, and the phenotype could be reverted upon reintroduction of C3G or its catalytic domain. Association of C3G with the basal body is dynamic, decreasing upon serum starvation, and increasing upon reentry into the cell cycle. C3G inhibits cilia formation and length dependent on its catalytic activity. We conclude that C3G inhibits centrosome duplication and maintains ciliary homeostasis, properties that may be important for its role in embryonic development.




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Salamander DNA reveals evidence of older land connection between Central and South America

The humble salamander may provide evidence to support a controversial claim that North and South America were joined together much earlier than previously thought. The […]

The post Salamander DNA reveals evidence of older land connection between Central and South America appeared first on Smithsonian Insider.




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Distinguishing space groups by electron channelling: centrosymmetric full-Heusler or non-centrosymmetric half-Heusler?

X-ray emission under electron-channelling conditions is used to distinguish between a non-centrosymmetric half-Heusler and a centrosymmetric full-Heusler crystal. For TiCo1.5+xSn the space-group determination based on a Rietveld refinement procedure became challenging for increasing Co content (x > 0.2), while electron channelling proved successful for higher Co content (x = 0.35). This technique can be used on crystals as small as (10 nm)3.




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How to Backup Contacts and Autocomplete Entries in Outlook




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Feathered diplomats unite pupils in North and Central America

By now, most of the United States has started to feel the first cool caresses of winter. Everything is pumpkin spiced, and the last crickets […]

The post Feathered diplomats unite pupils in North and Central America appeared first on Smithsonian Insider.




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Study dates corn as staple crop in Central America beginning 4,300 years ago

Corn, known also as maize, is a vital crop in the U.S. and throughout the Americas. First domesticated in Mexico some 9,000 years ago, scientists […]

The post Study dates corn as staple crop in Central America beginning 4,300 years ago appeared first on Smithsonian Insider.




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Doubt about Upgrading a lenovo ideacentre 300-20ish and GPU and CPU temeperature




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Sopra Banking, Centric to deliver core banking platform and could solutions to FIs

Sopra Banking Software (SBS), a global digital banking...




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Statement Regarding National Academies Study on Potential Health Risks of Living in Proximity to Surface Coal Mining Sites in Central Appalachia

In an August 18 letter, the U.S. Department of the Interior’s Office of Surface Mining Reclamation and Enforcement informed the National Academies of Sciences, Engineering, and Medicine that it should cease all work on a study of the potential health risks for people living near surface coal mine sites in Central Appalachia.




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New Report Calls for Lowering Blood Alcohol Concentration Levels for Driving, Increasing Federal and State Alcohol Taxes, Increasing Enforcement, Among Other Recommendations

Despite progress in recent decades, more than 10,000 alcohol-impaired driving fatalities occur each year in the U.S. To address this persistent problem, stakeholders -- from transportation systems to alcohol retailers to law enforcement -- should work together to implement policies and systems to eliminate these preventable deaths, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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The central role of NGOs in sustainable fisheries

The growing influence of non-governmental organisations (NGOs) in the seafood industry means that they now play a central role in setting standards for sustainable fisheries. In a new study, researchers used the Dutch Good Fish Guide to illustrate how NGOs can efficiently engage consumers, industry, fishermen and government.




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The European Soil Data Centre: a one-stop-shop for soil science

Since the arrival of the European Soil Data Centre in 2006, assessing the state of soils at European level has never been easier, more efficient or more reliable, according to a new report by its designers. The database, which contains state-of-the-art scientific information for a range of key environmental concerns, was accessed 26,000 times in the first 11 months of operation.




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Abandoned farmland widespread in central and eastern Europe

A new study suggests that abandoned farmland is widespread in Europe and that not all land that has been abandoned is unsuitable for farming. Understanding how abandoned farmland is distributed may be important for making land management decisions – for instance, recultivation versus reversion to forest.




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Concentrating Solar Power’s potential for Europe

A recent study has highlighted the potential of one form of solar power, Concentrating Solar Power (CSP), to make a significant contribution to meeting future electricity demands from renewable sources in Europe.




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Plastics can concentrate toxic pollutants, endangering marine ecosystems

Plastic debris is a serious environmental concern, as a physical pollutant as well as a chemical pollutant when it breaks down in the marine environment. A new study has now shown that plastics can also concentrate other pollutants, with significantly higher concentrations of toxic pollutants adhering to soft, rubbery plastics, rather than hard, glassy plastics.




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Energy-efficient data centres? How recovered waste heat could be sold to district heating networks, Finland

Concern is growing around the issue of energy efficiency in data centres (DC) as more and more data are saved, processed, and transferred to facilitate myriad digital services worldwide. Utilising waste heat from DCs as heating for nearby districts may be a potential solution if technical and knowledge barriers are overcome, suggests this Finnish study, which identified key obstacles to this concept and possible methods of implementation.




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The impacts of large-scale Concentrated Solar Power on the local environment

Construction of Concentrated Solar Power (CSP) plants – electricity generation which concentrates sunlight to generate heat – can have a range of negative effects on wildlife, but these effects are short lived, new research has found. Once in use, CSP plants can even have some positive effects, reducing soil erosion, for instance.




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Wetland management needs a ‘human-centric’ approach

Wetland management needs to consider the role wetlands play in supporting livelihoods and wellbeing as well as more traditional conservation goals, according to UK researchers. Such a ‘human-centric’ approach, would link hydrological conservation to societal benefits, including clean water, food production, flood protection and improved human health.




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Trade-offs in ecosystem services in Central and Eastern Europe

Researchers have developed a new approach for identifying regions that are most suitable for expanding ecosystem services. This could be used to help inform spatial planning decisions. By modelling ecosystem services’ opportunity costs in relation to agricultural revenue, the study provides a map of suitable areas of ecosystem service expansion in Eastern Europe.




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Mobile-centric approach driving growth: MakeMyTrip

A mobile-centric approach and the emergence of new digital platforms fuelling greater adoption of e-commerce has driven reach and growth of MakeMyTrip, the online travel company said in a presentation to investors.




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Cloud contact centres

BT Cloud Contact Offers customers a complete contact center solution including in built omni-channel, embedded IVR, and an inbuilt customer relationship system as standard.




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The contact centre of the future

Contact centres may have poor reputations but they should be seen as a strategic resource, says Nicola Millard, BT’s in-house futurist




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Entrepreneurship key to successful Local Agenda 21 strategy

There has been a mixed response to Local Agenda 21 (LA21) across Europe, but a new study from the Basque Country in Spain has identified factors that contribute to a successful LA21 strategy. These are a local entrepreneurial presence, joint problem-solving and joint decision-making by local government members.




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Decentralised Flood Protection: key step to natural flood management

Scientists have modelled the potential benefits of decentralised flood protection (DFP) in Central Europe and conclude that it could be a significant step towards natural flood management in the EU.




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Degrowth aided by decentralised water supply

A new study from Spain has explored economic degrowth (the scaling back of economic models based on growth) in the water sector and indicates that rainwater harvesting and reclaimed water use are most aligned to degrowth principles.




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Polycentric governance could encourage effective river basin management

A new study has compared the water governance and management systems of nearly 30 river basins around the world. Results indicated that governance systems with distributed political power and good co-ordination help to implement the principles of good governance in water management practice, and to adopt more advanced climate change adaptation policies.




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Decentralised supply of recycled water may save energy and reduce greenhouse gas emissions

Reusing waste water for non-drinking uses in decentralised plumbing networks may improve the efficiency of water supply in urban areas, a new study has found. Modelling this approach in San Francisco, researchers found that, depending on the local geography, a decentralised water supply could lead to energy savings and reductions in greenhouse gas emissions from water treatment of around 30%. Improvements in emerging water-treatment technologies are likely to lead to further savings, which could help increase the efficiency of urban water supply.




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Don’t forward work emails to a personal a/c, separate work & life: Centre

“Create a separate user profile with minimal privileges for work-only use. Close all work-related windows, applications, files, and documents when not in use. Do not use work email addresses to sign up for unauthorised, free tools. Grant access to your employees to corporate network only though a company-approved VPN with multi-factor authentication,” the advisory states.




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With 7.45 lakh followers, RBI most popular among central banks on Twitter

With the microblogging site emerging as a key platform for information dissemination, many central banks are active on Twitter, especially in these times of economic uncertainties amid the coronavirus pandemic.




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Modular data centres eliminate the need for specialised support skillsets: Opinion

Modular data centres are attractive options to power next-gen applications such as Internet of Things (IoT), industrial process control and smart cities. Radical edge computing possibilities are on offer.




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Nutanix sets up second customer support centre in India

The new center takes the total number of Customer Support Centres of Excellence to ten, five of which are based in Asia.




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Amazon beefs up cloud business, data centre infrastructure in India

Amazon is beefing up its data centre infrastructure and cloud services business in India as the clamour around data localisation grows louder everyday.