hem

Some dolphins cross the Pacific more easily than others. Why that matters for protecting them

Marine mammologist Matthew Leslie aims his crossbow from the bow of a moving boat at the dolphins riding the breaking waves below. A dolphin will […]

The post Some dolphins cross the Pacific more easily than others. Why that matters for protecting them appeared first on Smithsonian Insider.




hem

Mitochondrial-nuclear heme trafficking is regulated by GTPases in control of mitochondrial dynamics and ER contact sites [RESEARCH ARTICLE]

Osiris Martinez-Guzman, Mathilda M. Willoughby, Arushi Saini, Jonathan V. Dietz, Iryna Bohovych, Amy E. Medlock, Oleh Khalimonchuk, and Amit R. Reddi

Heme is a cofactor and signaling molecule that is essential for much of aerobic life. All heme-dependent processes in eukaryotes require that heme is trafficked from its site of synthesis in the mitochondria to hemoproteins located throughout the cell. However, the mechanisms governing the mobilization of heme out of the mitochondria, and the spatio-temporal dynamics of these processes, are poorly understood. Herein, using genetically encoded fluorescent heme sensors, we developed a live cell assay to monitor heme distribution dynamics between the mitochondrial inner-membrane, where heme is synthesized, and the mitochondrial matrix, cytosol, and nucleus. Surprisingly, heme trafficking to the nucleus is ~25% faster than to the cytosol or mitochondrial matrix, which are nearly identical, potentially supporting a role for heme as a mitochondrial-nuclear retrograde signal. Moreover, we discovered that the heme synthetic enzyme, 5-aminolevulinic acid synthase (ALAS), and GTPases in control of the mitochondrial dynamics machinery, Mgm1 and Dnm1, and ER contact sites, Gem1, regulate the flow of heme between the mitochondria and nucleus. Overall, our results indicate that there are parallel pathways for the distribution of bioavailable heme.





hem

Tropical forests “fix” themselves

Tropical forests speed their own recovery, capturing nitrogen and carbon faster after being logged or cleared for agriculture. Researchers working at the Smithsonian Tropical Research […]

The post Tropical forests “fix” themselves appeared first on Smithsonian Insider.




hem

Mystery solved? Ants Protect Young From Infection By Cocooning Them in Fungus

In the dark recesses of an underground fungus garden, a Panamanian leaf-cutting ant plucks a tuft of mycelia, the wispy part of the basidiomycete fungus […]

The post Mystery solved? Ants Protect Young From Infection By Cocooning Them in Fungus appeared first on Smithsonian Insider.




hem

Mongooses wiped them out. Now Nicole Angeli wants the St. Croix ground lizard home again

To catch lizards on the offshore islands close to St. Croix in the Caribbean, Smithsonian herpetologist Nicole Angeli uses a lasso of thread looped at […]

The post Mongooses wiped them out. Now Nicole Angeli wants the St. Croix ground lizard home again appeared first on Smithsonian Insider.




hem

Crape myrtle trees aren’t native to the US, but hungry native birds still find them tasty

Each year from summer into fall, ornamental crape myrtle trees in the southern and central U.S. lay out a visual feast of vibrant flowers in […]

The post Crape myrtle trees aren’t native to the US, but hungry native birds still find them tasty appeared first on Smithsonian Insider.




hem

Deciphering the hydrogen-bonding scheme in the crystal structure of tri­phenyl­methanol: a tribute to George Ferguson and co-workers

The crystal structure of tri­phenyl­methanol, C19H16O, has been redetermined using data collected at 295 and 153 K, and is compared to the model published by Ferguson et al. over 25 years ago [Ferguson et al. (1992). Acta Cryst. C48, 1272–1275] and that published by Serrano-González et al., using neutron and X-ray diffraction data [Serrano-González et al. (1999). J. Phys. Chem. B, 103, 6215–6223]. As predicted by these authors, the hy­droxy groups are involved in weak inter­molecular hydrogen bonds in the crystal, forming tetra­hedral tetra­­mers based on the two independent mol­ecules in the asymmetric unit, one of which is placed on the threefold symmetry axis of the Roverline{3} space group. However, the reliable determination of the hy­droxy H-atom positions is difficult to achieve, for two reasons. Firstly, a positional disorder affects the full asymmetric unit, which is split over two sets of positions, with occupancy factors of ca 0.74 and 0.26. Secondly, all hy­droxy H atoms are further disordered, either by symmetry, or through a positional disorder in the case of parts placed in general positions. We show that the correct description of the hydrogen-bonding scheme is possible only if diffraction data are collected at low temperature. The pro­chiral character of the hydrogen-bonded tetra­meric supra­molecular clusters leads to enanti­omorphic three-dimensional graphs in each tetra­mer. The crystal is thus a racemic mixture of supS and supR motifs, consistent with the centro­symmetric nature of the Roverline{3} space group.




hem

LaTe1.82(1): modulated crystal structure and chemical bonding of a chalcogen-deficient rare earth metal polytelluride

Crystals of the rare earth metal polytelluride LaTe1.82(1), namely, lanthanum telluride (1/1.8), have been grown by molten alkali halide flux reactions and vapour-assisted crystallization with iodine. The two-dimensionally incommensurately modulated crystal structure has been investigated by X-ray diffraction experiments. In contrast to the tetra­gonal average structure with unit-cell dimensions of a = 4.4996 (5) and c = 9.179 (1) Å at 296 (1) K, which was solved and refined in the space group P4/nmm (No. 129), the satellite reflections are not compatible with a tetra­gonal symmetry but enforce a symmetry reduction. Possible space groups have been derived by group–subgroup relationships and by consideration of previous reports on similar rare earth metal polychalcogenide structures. Two structural models in the ortho­rhom­bic superspace group, i.e. Pmmn(α,β,1 over 2)000(−α,β,1 over 2)000 (No. 59.2.51.39) and Pm21n(α,β,1 over 2)000(−α,β,1 over 2)000 (No. 31.2.51.35), with modulation wave vectors q1 = αa* + βb* + 1 over 2c* and q2 = −αa* + βb* + 1 over 2c* [α = 0.272 (1) and β = 0.314 (1)], have been established and evaluated against each other. The modulation describes the distribution of defects in the planar [Te] layer, coupled to a displacive modulation due to the formation of different Te anions. The bonding situation in the planar [Te] layer and the different Te anion species have been investigated by density functional theory (DFT) methods and an electron localizability indicator (ELI-D)-based bonding analysis on three different approximants. The temperature-dependent electrical resistance revealed a semiconducting behaviour with an estimated band gap of 0.17 eV.




hem

#Chemsafety at #ACSSanDiego

Here’s what’s planned for chemical and laboratory safety at the ACS National Meeting in San Diego, which starts on Sunday. You can also take advantage of the Division of Chemical Health & Safety’s printer-friendly CHAS-At-A-Glance. Sunday, Aug. 25 Committee on Chemical Safety Open and Executive Subcommittee Meeting, 7:00–10:00 am, Marriott Marquis San Diego Marina, Marina […]

The post #Chemsafety at #ACSSanDiego appeared first on CENtral Science.




hem

New UK bank scheme leads to 100,000 loan applications on first day

UK-based banks have received around 100,000 applications in a single day after The Bounce Back Loans scheme for small businesses was released.




hem

Theme selector




hem

[GUIDE] How To Make Your Own Customized Theme For PSP ?




hem

Cold War Chemical Tests Over American Cities Were Far Below Dangerous Levels

A series of secret tests conducted by the U.S. Army in the 1950s and 1960s did not expose residents of the United States and Canada to chemical levels considered harmful, according to a new report from a committee of the National Research Council.




hem

Need Still Exists for Chemical Pesticides While Alternatives Are Sought

No justification currently exists for completely abandoning chemical pesticides, says a new report from the National Academies National Research Council.




hem

Adding It Up - Helping Children Learn Mathematics

American students progress toward proficiency in mathematics requires major changes in instruction, curricula, and assessment in the nations schools, says a new report from the National Research Council of the National Academies.




hem

Limited Data Suggest Possible Association Between Agent Orange Exposure And Ischemic Heart Disease And Parkinsons Disease In Vietnam Veterans

A new report from the Institute of Medicine finds suggestive but limited evidence that exposure to Agent Orange and other herbicides used during the Vietnam War is associated with an increased chance of developing ischemic heart disease and Parkinsons disease for Vietnam veterans.




hem

Research Priorities for the Field of Atmospheric Chemistry – New Report

Increasing energy demands and expanding industrial and agricultural activities worldwide are changing the composition of the atmosphere and contributing to major global challenges like climate change and air pollution. The study of atmospheric chemistry plays a key role in understanding and responding to these challenges, and research in this field has been successful in guiding policies to improve air quality in urban areas and reduce acid rain and stratospheric ozone depletion.




hem

New Report Lays Out Strategy to Evaluate Evidence of Adverse Human Health Effects From Endocrine-Disrupting Chemicals at Low Doses

A new report by the National Academies of Sciences, Engineering, and Medicine proposes a strategy that the U.S. Environmental Protection Agency (EPA) should use to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system.




hem

New Report Calls for Greater Oversight of Precursor Chemicals Sold At the Retail Level to Reduce Threats from Improvised Explosive Devices

Policymakers’ efforts to reduce threats from improvised explosive devices (IEDs) should include greater oversight of precursor chemicals sold at the retail level – especially over the Internet – that terrorists, violent extremists, or criminals use to make homemade explosives, says a new report from the National Academies of Sciences, Engineering, and Medicine.




hem

FAA Should Change Its Safety Risk Assessment Approach for Drones to Effectively Integrate Them Into the Nation’s Airspace

Introducing drone operations into the nation’s airspace can provide substantial benefits to society, such as preventing derailments, inspecting cell phone towers, delivering medical devices to patients in cardiac distress, and assisting firefighters, says a new congressionally mandated report by the National Academies of Sciences, Engineering, and Medicine.




hem

How to Enable Dark Mode Theme in Windows 10




hem

New Ransomware as a Service (RaaS) site powers affiliate ransomware scheme




hem

Where to download laptop motherboard schematics?




hem

Ebury authorised to provide SME funding under Italian Government's coronavirus guarantee scheme

Ebury is the first non-bank financial institution to be granted...





hem

First steps to eliminate hazardous chemicals in plastic

By ranking the ???hazard potential??? of a wide range of chemicals used to make common plastics, Swedish researchers have highlighted which plastic polymers are made from the most hazardous chemicals. These should be prioritised for assessing the risk of causing human or environmental harm.




hem

Evidence for effects of chemical pollution on riverbed invertebrates

To date, it has been difficult to collect data that are robust enough to demonstrate specific effects of chemical pollution in rivers on aquatic wildlife. However, a recent study combining detailed chemical, toxicological and ecological data in three European river basins now provides evidence linking cause and effect by revealing significant differences in the effects of differently polluted sediments on the organisms living in the river basins and the riverbed biodiversity.




hem

Twitter warns of legacy site theme shutting down on June 1

Twitter is warning users impersonating unsupported browsers to enable the original site theme that the legacy version will be shut down on June 1st, 2020. [...]




hem

Antimicrobial chemicals found with antibiotic-resistance genes in indoor dust

University of Oregon researchers have found links between the levels of antimicrobial chemicals and antibiotic-resistance genes in the dust of an aging building used for athletics and academics.

read more



  • Health & Medicine

hem

Agri-environment schemes are based more on 'common sense'

New research has indicated that the design of a high proportion of agri-environmental policy measures in seven EU countries was based on common sense judgments about their possible impact. Only a sixth of the measures studied were based on well-tested quantitative models of their relationship to the environment.




hem

Influences on uptake of agri-environmental schemes in Spain

New research in southern Spain has studied what influences participation in agri-environmental schemes (AES). It indicated that the uptake of schemes that involve a major change in farm practices depends on the farm structure, whereas for schemes with minor changes, individual farmer characteristics play a greater role.




hem

Combination Effects of Chemicals

Outside the laboratory, living organisms are never subject to single stressors at set doses. In the real world, they face an intricate array of physical, chemical and biological environmental stressors that vary in space and time. The problem of assessing these complex risks for human health and the environment is a great challenge for scientists and regulators alike. For example, even if Maximum Permissible Concentrations (MPCs) for individual contaminants are not exceeded in water, in combination they can still be potentially hazardous to wildlife. This thematic issue reports on scientific research which can help us overcome some of the challenges associated with assessing the combination effects of chemicals.




hem

How bridging organisations aid design and uptake of EU agri-environment schemes

Managing landscapes effectively requires the involvement of a wide variety of stakeholders. The views and interests of these different groups can be effectively integrated by agri-environment 'collaboratives' — a type of bridging organisation which can be found in varying forms in Europe. Using data from Germany and the Netherlands, a study concludes that these groups make important contributions to landscape management, ranging from implementing policy to generating income.




hem

EU's eco-management scheme shows positive long-term impacts

Standards for environmental management, such as EMAS and ISO 14001, aim to help organisations become more sustainable, but they have received little evaluation. A new Italian study is the first to quantitatively compare the impacts of these two standards. Its results suggest that EMAS's stipulation that organisations must report their ongoing performance may bring sustained environmental benefits in the longer term.




hem

Can loans scheme encourage green refurbishment of homes?

A UK Government scheme, designed to help finance energy efficiency improvements in the home, has been assessed in a recent study. The researchers advise that better information for homeowners is needed to encourage uptake of the ‘Green Deal’ initiative, and point to Germany’s Passivhaus standard as an aspirational model for green retrofitting.




hem

Rising CO2’s impacts on marine ecosystems and the people that rely on them

The world’s ocean ecosystems will suffer warming, increased acidity, low oxygen and reduced primary food supply as a result of rising CO2 and this is likely to have dramatic environmental and social impacts, a new study concludes. It predicts that the most vulnerable low-income countries, where 870 million people are dependent on marine ecosystems, would be affected if CO2 emissions are not tackled.




hem

‘Chemical footprint’ in development

A measure of ‘chemical footprint’ is being developed by researchers to assess the environmental impacts of the toxic chemicals released by the production and consumption of goods. The methodology, based on life cycle and risk assessment, is also designed to be linked to the resilience of ecosystems to chemical exposure.




hem

Magellan gps how to save address and access them




hem

Solar geoengineering schemes impacts differ across regions

Injecting light-reflecting particles into the atmosphere to counteract rising levels of greenhouse gas emissions cannot stabilise both temperatures and rainfall in all regions of the world at the same time, according to recent research. This raises serious questions about how such a process could be managed.




hem

NASA's THEMIS sees Auroras move to the rhythm of Earth's magnetic field

The majestic auroras have captivated humans for thousands of years, but their nature -- the fact that the lights are electromagnetic and respond to solar activity -- was only realized in the last 150 years. Thanks to coordinated multi-satellite observations and a worldwide network of magnetic sensors and cameras, close study of auroras has become possible over recent decades. Yet, auroras continue to mystify, dancing far above the ground to some, thus far, undetected rhythm.

read more



  • Astronomy & Space

hem

Learning from Ecuador’s national conservation incentive scheme

Payments for Ecosystem Services (PES) schemes offer direct payments for communities and individuals in exchange for conserving areas of land reserved for conservation for their environmental qualities. The results of an Ecuadorian study highlight key aspects for designing successful PES schemes and demonstrate how investments associated with PES can also benefit poor communities.




hem

Neighbours can influence farmer participation in PES schemes

Understanding the role of neighbourhood networks in encouraging farmers to participate in Payments for Ecosystem Services (PES) schemes is important as this can help to create local patterns of high and coordinated uptake of PES schemes, and thus an impact on ecosystem protection at a wider, landscape level. This is the outcome of a recent UK study, which found that neighbourhood networks were particularly important for small, remote communities.




hem

Agri-environmental schemes need co-ordinating across landscapes

According to a recent viewpoint article, future agri-environmental schemes (AES) can more effectively pay for the provision of ecosystem services at a landscape level if they are prepared, designed and implemented in a collaborative and coordinated manner.




hem

Kerbside waste-collection schemes may need optimisation, highlights Portuguese study

A new analysis of waste recycling systems in Portugal highlights where kerbside (edge of pavement) collection systems could be optimised, to decrease their environmental impact. In this case, researchers found that the kerbside system was less favourable economically and environmentally due to more packaging and more fuel consumption per tonne of waste, compared to a system where recyclable materials are deposited by residents in large containers. But the researchers suggest that measures such as re-usable boxes and efficient collection routes could help to mitigate the impact of kerbside collection. While there is an environmental impact from waste collection, processing and disposal, this study only focused on the collection phase.




hem

Posting personal experiences on social media may help you remember them in the future

A new study -- the first to look at social media's effect on memory -- suggests posting personal experiences on social media makes those events much easier to recall.

read more



  • Psychology & Sociology