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Durant tops list of Warrior trade targets

AFTER suffering an NBA Finals defeat to ruin the best regular season in history, Golden State’s owner promised to be “very aggressive”.




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Découvrez l’étrange rituel du chanteur de Coldplay

Chris Martin a intrigué les badauds lundi en embrassant le tarmac de l’aéroport de Sydney.




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Guylaine Tanguay tiendra la vedette de la mouture québécoise de la comédie musicale «Ménopause»: «J’ai besoin de me mettre en danger»

Elle tiendra la vedette de l’adaptation québécoise du succès mondial Ménopause aux côtés de Claudine Mercier, Catherine Sénart et Geneviève Charest.




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These guys are not exactly ‘dole bludgers’

DOCTORS from a top Australian university say they too were hit with erroneous Centrelink debt notices — and even a PhD can’t sort out the mess.




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The gadget for the perfect coffee

IF you buy a large cappuccino you may find it is quite cold by the time you get to the bottom. Thankfully, there is now a solution to this.




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Apple’s biggest product since the iPhone

APPLE could be set to make its biggest new product announcement since the iPhone, with the company believed to be working on a game changer.




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Baby milk price promotion ban should end, watchdog suggests

Many parents opt for more expensive baby milk, equating higher costs with better quality, the watchdog found.




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Bolt drivers win right to holiday and minimum wage

Thousands of drivers on ride-hailing and food delivery app Bolt have won a legal claim to be classed as workers.




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Homeworkers get 24 more minutes of sleep a day

Office for National Statistics data suggests homeworkers get more sleep and exercise on average.




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Legal challenge to Rosebank oil field begins

Campaigners want to stop the Rosebank oil and Jackdaw gas fields, but oil companies say they are vital.




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ALP told to ‘get better policies’

A review of Labor’s City of Sydney council campaign finds earlier preselections and better policies are needed.




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Unions’ grip strongest in admin

Those who work in public administration and defence operate in the most heavily unionised sector of the labour market.




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Passengers in safe hands

Flying has never been safer for Australians on commercial aircraft, according to a new report from the ATSB.




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Open up on US refugee deal: ALP

Labor has urged Malcolm Turnbull to be more transparent about the deal reached to resettle refugees in the US.




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Flagged carers out on full pay

Four workers red-flagged in a 2014 review of SA’s troubled child protection agency remain suspended on full pay.




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Judge anger on $10 art claim

A judge has issued a stinging rebuke to separating couples who expect the courts to decide frivolous disputes.




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Culleton lodges appeal

The ex-senator launches a last-ditch bid against a bankruptcy ruling, hoping to regain the seat he officially lost yesterday.




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Ironman legend Barry Rodgers dead at 74

LEGENDARY Ironman champion and long-serving swimming coach Barry Rodgers died yesterday aged 74 after battling cancer. He is remembered as “the embodiment of grit and determination”.




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Les fromages en portions individuelles au banc d’essai

Les fromages vendus en portions individuelles sont des plus pratiques pour l’école et le bureau.




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AIOCD urges DCGI to immediately stop partnership between Swiggy & PharmEasy for rapid drug delivery

Raising deep concern over the partnership between Swiggy Instamart and PharmEasy for a rapid drug delivery model, the All India Organization of Chemists and Druggists (AIOCD) has apprised the Drug Controller




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Indian pharma stresses for enhanced fire safety measures and improved insurance coverage for employees

The Indian pharmaceutical industry is advocating for enhanced fire safety measures and improved insurance coverage for employees working in pharmaceutical facilities.




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Asahi Kasei Medical launches Planova FG1 next-generation virus removal filter

Asahi Kasei Medical has launched the Planova FG1, a next-generation virus removal filter featuring higher flux for the manufacture of biotherapeutics, in October 2024.




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The latest trends and challenges in sterilisation

James Hicks, healthcare application development and processing engineer at Syensqo explores the latest trends, challenges and solutions in sterilisation.




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Gerresheimer wins Red Dot Award

Gerresheimer, an innovative system and solution provider, received a Red Dot Design Concept award for its Gx Inbeneo autoinjector platform.




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How the 2024 Election Could Change Access to Health Care in the U.S. and Influence Global Nuclear Policies

The outcome of the 2024 U.S. presidential election could reshape policies from health care at home to nuclear proliferation abroad




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The Virus That Causes Mpox Keeps Getting Better at Spreading in People

Analysis of a strain of the virus circulating in Central Africa shows genetic mutations indicative of sustained human-to-human spread




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How the 2024 Election Could Change Access to Education in the U.S. and Influence Global Climate Change Decisions

The outcome of the 2024 U.S. presidential election could set the climate agenda, reshape public education and shift the dynamics of global science collaboration.




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The Law Must Respond When Science Changes

What was once fair under the law may become unfair when science changes. The law must react to uphold due process




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We Need Scientific Brainstorming about Shared Global Dangers

It is difficult to disentangle Russian and Chinese scientists from international science cooperation. That is a good thing




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Let African Communities Manage Their Climate Adaptation Plans

Outside groups often offer their solutions for climate adaptation in Africa. But the best people to manage the climate crisis are the people in those communities themselves. For climate adaptation to succeed in Africa, let communities and local leaders show the way




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How Geometry Revealed Quantum Memory

The unexpected discovery of a geometric phase shows how math and physics are tightly intertwined




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A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

Charco Neurotech, a medtech company based in the United Kingdom, has developed CUE1, a non-invasive wearable that is intended to assist those with Parkinson’s disease to manage their motor symptoms. The device is typically affixed to the sternum, and provides vibratory action in a focused region of the body. The technology is based on the […]




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Hospitals Are Relying More on PBMs to Manage Manufacturers' 340B Contract Pharmacy Restrictions: DCI's 2024 Market Analysis (rerun)

This week, I’m rerunning some popular posts while we put the finishing touches on DCI’s new 2024-25 Economic Report on Pharmaceutical Wholesalers and Specialty Distributors.

Click here to see the original post from June 2024.



The 340B contract pharmacy market shows little sign of slowing down. Drug Channels Institute’s exclusive analysis of the 2024 market reveals that:
  • About 33,000 pharmacy locations—more than half of the entire U.S. pharmacy industry—act as contract pharmacies for the hospitals and federal grantees that participate in the 340B program. 
  • Five multi-billion-dollar, for-profit, publicly traded pharmacy chains and pharmacy benefit managers (PBMs)—Cigna (via Express Scripts), CVS Health, UnitedHealth Group (via OptumRx), and Walgreens, Walmart—continue to dominate the 340B contract pharmacy market.
  • Federal grantees are aligned primarily with the vertically intergated organizations' retail pharmacies, while hospitals rely on mail and specialty pharmacies.
Over the past four years, manufacturers’ restrictions on 340B contract pharmacies have led hospitals to deepen their relationships with the largest PBMs—even as those PBMs have simultaneously limited hospitals’ direct participation in specialty pharmacy networks.

For an updated look at what’s next for the 340B contract pharmacy market, join Adam J. Fein, Ph.D., on June 21 for his latest live video webinar: The 340B Drug Pricing Program: Trends, Controversies, and Outlook.
Read more »
       




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If Plan Sponsors Are So Unhappy with Their PBMs’ Transparency, Why Won’t They Change the Model?

A new survey of plan sponsors sheds light on their satisfaction with transparency at large and small pharmacy benefit managers (PBMs).

As you will see, clients remain slightly more satisfied with the perceived transparency of smaller PBMs compared with the Big Three PBMs—CVS Caremark, Express Scripts, and Optum Rx.

However, plan sponsors are dissatisfied with transparency about how both large and small PBMs make money. Smaller PBMs have an edge, but it’s narrower than you might think.

Perhaps PBMs’ clients are unable or unwilling to negotiate better deals, write more effective contracts, and switch to more satisfying relationships. Or maybe they don’t mind the current system, despite the challenges for patients. Some argue that transparency could swoop down to solve this problem. Riddle me this: Should we watch what plan sponsors say, or what they do?

Read on to see what you think of my arguments below. Then, click here to share your thoughts with the Drug Channels community.
Read more »
       




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How Field Reimbursement Services Help Overcome Coverage Barriers and Improve Patient Outcomes

Today’s guest post comes from Kimberley Chiang, Vice President of Biopharma Commercial Solutions at CoverMyMeds

Kimberley highlghts the crucial roles of field reimbursement managers in removing access and reimbursement barriers. She then identifies the keys to successful implementation of field reimbursement services.

To learn more, register for CoverMyMeds' November 13, 2024, webinar: Specialty Therapies & Field Reimbursement Services: Driving Better Outcomes for Brands and Patients.

Read on for Kimberley’s insights.
Read more »
       




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Transparency Shocker: Biosimilars Are Getting Cheaper—But Hospitals and Insurers Can Make Them Expensive

Here on Drug Channels, we have long highlighted the boom in provider-administered biosimilars. In contrast to the pharmacy market, adoption of these biosimilars is growing, prices are dropping, and formulary barriers continue to fall.

Novel transparency information reveals that this good news doesn’t always translate into savings. Below, we rely on a unique data set from Turquoise Health to examine how much four national commercial health plans—Aetna, Anthem, Cigna, and UnitedHealthcare—paid hospitals for Avastin and its two most significant biosimilar competitors.

As we demonstrate, health plans pay hospitals far above acquisition costs for biosimilars. What’s more, plans can pay hospitals more for a biosimilar than for the higher-cost reference product. The U.S. drug channel system is warping hospitals’ incentives to adopt biosimilars, while simultaneously raising costs for commercial plans.

The namesake of my alma mater once said: “Sunlight is said to be the best of disinfectants.” What would happen if we disinfected the entire channel?
Read more »
       




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Geek Bar 1

The U.S. Food and Drug Administration posted a photo:

Geek Bar e-cigarette seized during joint federal operation that resulted in the seizure of $76 million of illegal e-cigarettes.




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FDA Funding: Agency Mission “At Risk”, Says Alliance President

FDA’s mission is “at risk” because of inadequate funding. So says Alliance for a Stronger FDA President Diane Dorman, testifying before the FDA Science Board. Her remarks come 5 years after the Science Board made a similar declaration, concluding that decades of underfunding had left FDA without the resources to fulfill its mandate and make science-based decisions. Congress responded with more monies for the agency, but since then the FDA’s workload has increased even faster. The current threat to FDA comes from two sources: four major new laws to implement since 2009; and changes in the environment in which FDA operates, notably acceleration of globalization and increasing scientific complexity. Ms. Dorman’s remarks are reprinted below. If you care about FDA, FDA Matters urges you to read her testimony, go to the Alliance’s site (www.StrengthenFDA.org) and join.




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More Columns Coming; The Alliance for a Stronger FDA

FDA Matters appreciates your patience. New columns will be coming in June, with fresh insights into FDA and the FDA-regulated world.  Meantime, I write a weekly column in the Friday Update, published by the Alliance for a Stronger FDA. If you want to receive the Friday Update when it's published each week, you can sign […]




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The Defense of Science in the Age of Fake News

Fake news didn’t just become a problem because of Trump, or the pandemic. It’s been around for a long while. The problem can’t begin to be solved unless the medical and scientific community accepts that it has an absolute responsibility to aggressively debunk fake news and defend and support scientific principles. Click here to read...

Click here to continue reading...




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Bio-Thera and Gedeon Richter partner to commercialize Stelara biosimilar BAT2206

<p>In October 2024, China based Bio-Thera Solutions&nbsp;(Bio-Thera)&nbsp;and Hungary’s Gedeon Richter announced they have reached an exclusive commercialization and license agreement for BAT2206, a biosimilar candidate to&nbsp;Johnson &amp; Johnson’s Stelara (ustekinumab).</p>




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Transforming healthcare: CinnaGen’s leadership in follow-on biologicals/ biosimilars development and market expansion

<p> <b>Abstract</b><br />CinnaGen, the largest biopharmaceutical company in the MENA region, is a leader in developing follow-on biologicals/biosimilars. Dr&nbsp;Haleh Hamedifar, Chairperson of CinnaGen, spoke to GaBI<i>&nbsp;</i>(Generics and Biosimilars Initiative) about the company’s strategic focus, which includes expanding its product portfolio, entering highly regulated global markets, and advancing affordable treatments for conditions such as multiple sclerosis and&nbsp;immunological diseases—transforming healthcare in underserved regions.</p><p><b>Keywords</b>: Biosimilars, clinical development, commercialization, MENA</p>




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Semaglutide effective for weight loss in non-diabetic adults, research suggests

The type 2 diabetes mellitus drug semaglutide is effective for weight loss in non-diabetic overweight or obese adults, when taken alongside a reduced-calorie diet and exercise, researchers have found.




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MHRA to consult on making two progestogen-only contraceptives available without a prescription

Consultations on the reclassification of two progestogen-only contraceptive pills from prescription-only to pharmacy medicines have been launched.




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New drug cuts the risk of death in bladder cancer by 30% compared with chemotherapy, study suggests

A new type of drug that targets chemotherapy directly to cancer cells reduces the risk of death from the most common type of bladder cancer by 30%, a phase III trial in the New England Journal of Medicine has suggested.




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Deconstructing the Diligence Process: An Approach to Vetting New Product Theses

By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Ever wondered what goes into diligencing a new idea, program, company, or platform? While each diligence is unique and every investor will have

The post Deconstructing the Diligence Process: An Approach to Vetting New Product Theses appeared first on LifeSciVC.




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Pharmacology: The Anchor for Nearly Every Diligence

By Haojing Rong and Aimee Raleigh, as part of the From The Trenches feature of LifeSciVC This blog post is the second in a series on key diligence concepts and questions. If you missed the intro blog post yesterday, click

The post Pharmacology: The Anchor for Nearly Every Diligence appeared first on LifeSciVC.




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Neuro-Immunology: The Promise Of A Differentiated Approach To Neurodegenerative Disease

By Ivana Magovčević-Liebisch, CEO of Vigil Neuroscience, as part of the From The Trenches feature of LifeSciVC In the last decade, our industry has made great strides in combating cancer by harnessing the body’s own immune system. As it was

The post Neuro-Immunology: The Promise Of A Differentiated Approach To Neurodegenerative Disease appeared first on LifeSciVC.




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A Primer on Early-Stage Biotech VC

By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC From the outside, one might assume all biotech venture capital (VC) firms are more similar than different. However, once you look under the

The post A Primer on Early-Stage Biotech VC appeared first on LifeSciVC.



  • Biotech startup advice
  • From The Trenches
  • Talent

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Medicinal Chemistry In The Age Of Artificial Intelligence

By Peter Tummino, CSO of Nimbus Therapeutics, as part of the From The Trenches feature of LifeSciVC  “Over the next five to 10 years, our goal is to become a company that’s leading the world in personalized medicines, a company

The post Medicinal Chemistry In The Age Of Artificial Intelligence appeared first on LifeSciVC.