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Jordan's Energy Policy Key to Its Economy

With Syria in crisis and Egypt in flux, Jordan is being forced to adopt energy policies that put the country on a path to sustainable development.




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US Candidate Amy Pope Wins Tense Contest to Run UN Migration Agency

Geneva — Former White House adviser Amy Pope won a vote in Geneva on Monday to head the U.N. migration agency, prevailing in a tense contest against a Portuguese incumbent who had the support of European countries. The International Organization for Migration (IOM) said Pope would become the first woman to lead the organization when she begins her five-year term on Oct. 1. Pope, who served as Deputy Director General for Management and Reform at IOM, took leave to campaign against her boss Antonio Vitorino, who has been in the position since 2018. Pope wrote on Twitter she was "humbled and honored" to be chosen by IOM's 175 member states as new director general. "I am ready to work with ALL our member states and global partners to unleash the opportunities provided by effective, orderly and humane migration," she wrote. In 2021, Pope served as Senior Advisor on Migration to U.S. President Joe Biden, who publicly backed her candidacy. "As IOM's largest bilateral donor, the United States strongly supports Ms. Pope's vision and looks forward to working with her to implement the critical reforms necessary to create a more effective, inclusive IOM," U.S. Secretary of State Antony Blinken said in a statement. More than 100 million people are forcibly displaced around the world and IOM seeks to ensure humane and orderly migration and intervenes where needed. Vitorino, a former European Commissioner who is close to his compatriot United Nations Secretary General Antonio Guterres, had touted an increase in the body's annual budget among his successes. Asked about the contest earlier this year, Vitorino described it as unprecedented. "We have never happened to have an incumbent director general that faces a competition with one of his deputy generals. Let's call it an innovation," Vitorino told journalists in March. He said at the time he had Portugal's backing as well as the "strong encouragement" of the European Union.




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Jeremy Berkovits: The face of Jerusalem's popular American Colony Hotel


At the table: Maintaining the massive 12,000-square-foot compound amounts to many thousands of shekels a month, and the owners are eager for a return to normalcy.



  • hotel
  • business
  • The October 7 Massacre
  • Israel-Hamas War
  • At the Table

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A plea to my fellow Christians: Now is the time to stand up for the Jewish people


Your Jewish friends, neighbors, and co-workers undoubtedly feel unsafe at this moment, and you have an opportunity to show them they are not alone.




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Trump names Musk, Ramaswamy to lead newly formed gov't department


Trump said their work would conclude by July 4, 2026, adding that a smaller government would be a "gift" to the country on the 250th anniversary of the signing of the Declaration of Independence.




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Myanmar: Transition Within Transition

The elections are over and the transition towards a democratic government in Myanmar is currently underway. However, the sailing isn't smooth.




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The Beatles, 'BRAT' summer, and other 2025 Grammy nomination snubs, surprises

NEW YORK — It looks like the 2025 Grammy Awards may be a different kind of award show. Beyoncé leads the nods with 11, bringing her career total to a record-breaking 99 nominations. There’s an incredible diversity of genres represented across the major categories, and women continue to succeed. So… who didn’t make the cut? What were the best surprises of all? Let’s take a look. Country’s cool again… and it looks a little different. Country music has bled into other prominent genres and the Recording Academy has taken note. Country hybridists — like Beyoncé, Post Malone and first-time nominee […]...

Keep on reading: The Beatles, 'BRAT' summer, and other 2025 Grammy nomination snubs, surprises





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Somalia's Cabinet Appoints Odowa Yusuf Raage to Lead National Army Against Al-Shabaab

[Shabelle] Mogadishu, Somalia -- In a decisive move to strengthen national security, Somalia's Cabinet of Ministers has officially endorsed General Odowa Yusuf Raage as the Commander of the Somali National Army, according to a statement released after an emergency meeting held on Sunday night.




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Somalia Reappoints Gen Odawaa As Army Chief Amid Push Against Al-Shabaab

[Radio Dalsan] The Somali Council of Ministers has reappointed General Odowa Yusuf Raage as Commander of the Somali Armed Forces, replacing General Ibrahim Muhyiddin, during an emergency meeting held in Mogadishu on Sunday night.




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Trump says Musk, Ramaswamy will form outside group to advise White House on government efficiency

Trump says Musk, Ramaswamy will form outside group to advise White House on government efficiency




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The Myth of Christian Popularity




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The Future of Civic Freedoms: Lessons from My Time at CIVICUS

When I joined CIVICUS in 2019, I came in with two decades of work on influencing and monitoring public policies through grassroots and global activism. Joining CIVICUS as Secretary-General felt familiar, like returning home after a period of separation. My first international role in 2006 – as Campaign Director of the Global Call to Action […]




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Kathy Bates on not having reconstruction surgery after double mastectomy for breast cancer

Kathy Bates on not having reconstruction surgery after double mastectomy Kathy Bates revealed why she didn’t go for a reconstruction surgery after her double mastectomy and breast cancer diagnosis.In 2012, at age 64, the American Horror Story alum was diagnosed with breast cancer and...




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to write a paper about myself

to write a paper about myself




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Integrated Services and Livelihood for Displaced People from Myanmar and Host Communities Improvement Project

The project will continue the support of the Asian Development Bank (ADB) to Bangladesh in managing the influx of around one million displaced people from Myanmar (DPFM) since 2017. Now a protracted situation, the crisis is putting significant pressure on infrastructure and causing substantial challenges in terms of food, shelter, health, security, water, sanitation, and other services in the DPFM camps and host communities.




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Has the mystery of life’s 'handedness' finally been cracked?

All living creatures use only the left or right-handed forms of certain molecules, and now we might understand why




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Solving Stephen Hawking’s black hole paradox has raised new mysteries

Physicists finally know whether black holes destroy the information contained in infalling matter. The problem is that the answer hasn’t lit the way to a new understanding of space-time




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Particle physicists may have solved a strange mystery about the muon

A subatomic particle called the muon caused waves when its experimental behaviour didn't align with a prediction based on the standard model. A new calculation might resolve the discrepancy – but some particle physicists are sceptical




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The laws of physics appear to follow a mysterious mathematical pattern

The symbols and mathematical operations used in the laws of physics follow a pattern that could reveal something fundamental about the universe




my

Solving Stephen Hawking’s black hole paradox has raised new mysteries

Physicists finally know whether black holes destroy the information contained in infalling matter. The problem is that the answer hasn’t lit the way to a new understanding of space-time




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Siberia’s mysterious exploding craters may be caused by hot gas

Several enormous craters left by explosions have been spotted in Siberia over the past 15 years, and a new explanation links them to hot gas – and climate change




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What are the mysterious continent-sized lumps deep inside Earth?

For decades, planetary scientists have been trying to understand the origins of two colossal geological anomalies inside our planet. New insights suggest they could be leftovers from a cosmic collision




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Human brains have been mysteriously preserved for thousands of years

Intact human brains 12,000 years old or more have been found in unexpected places such as shipwrecks and waterlogged graves, but it is unclear what preserved them




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Ancient people carved mysterious symbols near dinosaur footprints

A unique site in Brazil features rock carvings closely associated with dinosaur tracks, suggesting prehistoric people saw the footprints as meaningful




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Mysterious rock art in Venezuela hints at little-known ancient culture

Pictograms and petroglyphs depicting abstract lines and shapes offer a rare glimpse into the culture of people who lived in South America thousands of years ago




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Why the amazing Altamura Man fossil remains a mystery

A Neanderthal skeleton was discovered encased in rock in an Italian cave 30 years ago, but it hasn’t been studied much due to a long-running impasse about how to safely excavate it




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Study: Acupuncture Helps Fibromyalgia

Title: Study: Acupuncture Helps Fibromyalgia
Category: Health News
Created: 8/25/2005 12:00:00 AM
Last Editorial Review: 8/25/2005 12:00:00 AM




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Health Tip: Living With Fibromyalgia

Title: Health Tip: Living With Fibromyalgia
Category: Health News
Created: 8/30/2012 8:05:00 AM
Last Editorial Review: 8/30/2012 12:00:00 AM




my

'Pretend Mommy' Program Doesn't Deter Teen Pregnancy

Title: 'Pretend Mommy' Program Doesn't Deter Teen Pregnancy
Category: Health News
Created: 8/25/2016 12:00:00 AM
Last Editorial Review: 8/26/2016 12:00:00 AM




my

Health Tip: Understanding Vasectomy

Title: Health Tip: Understanding Vasectomy
Category: Health News
Created: 8/28/2018 12:00:00 AM
Last Editorial Review: 8/28/2018 12:00:00 AM




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Smoking, Drinking a Double Whammy for Teens' Arteries: Study

Title: Smoking, Drinking a Double Whammy for Teens' Arteries: Study
Category: Health News
Created: 8/29/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM




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AHA News: Mysterious Stroke at 38 Changed How Popular Speaker Connects With a Crowd

Title: AHA News: Mysterious Stroke at 38 Changed How Popular Speaker Connects With a Crowd
Category: Health News
Created: 8/28/2019 12:00:00 AM
Last Editorial Review: 8/29/2019 12:00:00 AM




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Michigan Officials Puzzled by Mysterious Deaths of 30 Dogs

Title: Michigan Officials Puzzled by Mysterious Deaths of 30 Dogs
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM




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When Should I Be Concerned About My Sick Baby?

Title: When Should I Be Concerned About My Sick Baby?
Category: Diseases and Conditions
Created: 8/24/2021 12:00:00 AM
Last Editorial Review: 8/23/2022 12:00:00 AM




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How Do I Get My Baby to Sleep Longer at Night?

Title: How Do I Get My Baby to Sleep Longer at Night?
Category: Diseases and Conditions
Created: 8/18/2021 12:00:00 AM
Last Editorial Review: 8/23/2022 12:00:00 AM




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How Can I Keep My Baby Cool in the Car Seat?

Title: How Can I Keep My Baby Cool in the Car Seat?
Category: Health and Living
Created: 3/17/2022 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM




my

How Can I Help My Toddler With Sleep Problems?

Title: How Can I Help My Toddler With Sleep Problems?
Category: Diseases and Conditions
Created: 6/17/2021 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM




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How Do I Make My Ears Stop Ringing?

Title: How Do I Make My Ears Stop Ringing?
Category: Diseases and Conditions
Created: 5/10/2022 12:00:00 AM
Last Editorial Review: 5/10/2022 12:00:00 AM




my

How Can I Dry Up Fluid in My Inner Ear?

Title: How Can I Dry Up Fluid in My Inner Ear?
Category: Diseases and Conditions
Created: 11/8/2021 12:00:00 AM
Last Editorial Review: 6/29/2022 12:00:00 AM




my

Why is My Blood Pressure Suddenly High and Low?

Title: Why is My Blood Pressure Suddenly High and Low?
Category: Diseases and Conditions
Created: 7/6/2022 12:00:00 AM
Last Editorial Review: 7/6/2022 12:00:00 AM




my

When Should I Start Cleaning My Baby’s Mouth?

Title: When Should I Start Cleaning My Baby’s Mouth?
Category: Diseases and Conditions
Created: 11/9/2020 12:00:00 AM
Last Editorial Review: 8/11/2022 12:00:00 AM




my

Why Is My Period More Heavy Than Usual?

Title: Why Is My Period More Heavy Than Usual?
Category: Diseases and Conditions
Created: 6/28/2022 12:00:00 AM
Last Editorial Review: 6/28/2022 12:00:00 AM




my

MS (Multiple Sclerosis) vs. ALS (Amyotrophic Lateral Sclerosis)

Title: MS (Multiple Sclerosis) vs. ALS (Amyotrophic Lateral Sclerosis)
Category: Diseases and Conditions
Created: 6/16/2017 12:00:00 AM
Last Editorial Review: 8/4/2022 12:00:00 AM




my

Is Chlamydia Contagious?

Title: Is Chlamydia Contagious?
Category: Diseases and Conditions
Created: 5/28/2015 12:00:00 AM
Last Editorial Review: 8/1/2022 12:00:00 AM




my

tobramycin

Title: tobramycin
Category: Medications
Created: 8/2/2022 12:00:00 AM
Last Editorial Review: 8/2/2022 12:00:00 AM




my

erythromycin

Title: erythromycin
Category: Medications
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 6/17/2022 12:00:00 AM




my

How to Get Rid of Mucus in My Chest Fast

Title: How to Get Rid of Mucus in My Chest Fast
Category: Diseases and Conditions
Created: 6/22/2022 12:00:00 AM
Last Editorial Review: 6/22/2022 12:00:00 AM




my

Promoting Male Involvement in Family Planning: Insights From the No-Scalpel Vasectomy Program of Davao City, Philippines

ABSTRACTDespite global consensus on the importance of male involvement in family planning, disparities persist in low- and middle-income countries, where women continue to bear the responsibility for these initiatives. The Philippines, with a high fertility rate and unmet family planning needs, exemplifies this challenge. We present the experiences and lessons learned from implementing the no-scalpel vasectomy (NSV) program in Davao City, showcasing its potential for increasing male engagement in family planning decisions. Launched in 2008, the program aimed to address gender disparity by promoting NSV as a safe and effective contraceptive alternative to female-centric methods. Through the use of culturally sensitive information campaigns and couple-focused counseling, the program challenged traditional notions of masculinity and encouraged shared decision-making. Strong local government commitment and public-private partnerships played key roles in driving the program’s success. Results showed an average annual increase of 80% in NSV clients over the past 3 years compared to before the COVID-19 pandemic, underscoring its effectiveness. The program presents a compelling intervention model for similar initiatives, highlighting how overcoming cultural barriers, infrastructure limitations, and budgetary constraints through policy advocacy, strategic partnerships, and tailored approaches can significantly boost male involvement in family planning and improve reproductive health outcomes within communities.




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Cannabinoid 2 Receptor Activation Protects against Diabetic Cardiomyopathy through Inhibition of AGE/RAGE-Induced Oxidative Stress, Fibrosis, and Inflammasome Activation [Special Section: Cannabinoid Signaling in Human Health and Disease]

Oxidative stress, fibrosis, and inflammasome activation from advanced glycation end product (AGE)–receptor of advanced glycation end product (RAGE) interaction contribute to diabetic cardiomyopathy (DCM) formation and progression. Our study revealed the impact of β-caryophyllene (BCP) on activating cannabinoid type 2 receptors (CB2Rs) against diabetic complication, mainly cardiomyopathy and investigated the underlying cell signaling pathways in mice. The murine model of DCM was developed by feeding a high-fat diet with streptozotocin injections. After the development of diabetes, the animals received a 12-week oral BCP treatment at a dose of 50 mg/kg/body weight. BCP treatment showed significant improvement in glucose tolerance and insulin resistance and enhanced serum insulin levels in diabetic animals. BCP treatment effectively reversed the heart remodeling and restored the phosphorylated troponin I and sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2a expression. Ultrastructural examination showed reduced myocardial cell injury in DCM mice treated with BCP. The preserved myocytes were found to be associated with reduced expression of AGE/RAGE in DCM mice hearts. BCP treatment mitigated oxidative stress by inhibiting expression of NADPH oxidase 4 and activating phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/nuclear factor erythroid 2–related factor 2 (Nrf2) signaling. Also, BCP suppressed cardiac fibrosis and endothelial-to-mesenchymal transition in DCM mice by inhibiting transforming growth factor β (TGF-β)/suppressor of mothers against decapentaplegic (Smad) signaling. Further, BCP treatment suppressed nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3 (NLRP3) inflammasome activation in DCM mice and alleviated cellular injury to the pancreatic tissues evidenced by significant elevation of the number of insulin-positive cells. To demonstrate a CB2R-dependent mechanism of BCP, another group of DCM mice were pretreated with AM630, a CB2R antagonist. AM630 was observed to abrogate the beneficial effects of BCP in DCM mice. Taken together, BCP demonstrated the potential to protect the myocardium and pancreas of DCM mice mediating CB2R-dependent mechanisms.

SIGNIFICANCE STATEMENT

BCP, a CB2R agonist, shows protection against DCM. BCP attenuates oxidative stress, inflammation, and fibrosis in DCM via activating CB2Rs. BCP mediating CB2R activation favorably modulates AGE/RAGE, PI3K/AKT/Nrf2β and TGF-β/Smad and (NLRP3) inflammasome in diabetic cardiomyopathy.